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Tumours Of The Mouse
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Book Synopsis International Classification of Rodent Tumors. The Mouse by : Ulrich Mohr
Download or read book International Classification of Rodent Tumors. The Mouse written by Ulrich Mohr and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists from both academia and industry in many countries have closely cooperated to arrive at a consensus on the descriptions of all the types of tumour and preneoplastic lesions encountered in laboratory mice. The series of fascicles should provide information and guidelines especially adapted for international use in practical toxicologic pathology. Images showing the typical appearance of the discussed lesions and references to the most recently published papers complete the information presented here.
Book Synopsis Patient-Derived Mouse Models of Cancer by : Robert M. Hoffman
Download or read book Patient-Derived Mouse Models of Cancer written by Robert M. Hoffman and published by Springer. This book was released on 2017-08-01 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems
Book Synopsis Tumours of the Mouse by : Vladimir Stanislavovich Turusov
Download or read book Tumours of the Mouse written by Vladimir Stanislavovich Turusov and published by . This book was released on 1994 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Pathology of Tumours in Laboratory Animals was initiated by the International Agency for Research on Cancer 25 years ago, to provide experimental pathologists with a comprehensive, coherent source of reference information, for use in chronic toxicology research. The first edition of the volume describing tumors of the mouse was issued in 1979. Since then many papers describing new models, new methods of induction, immunohistochemical methods, or important new details of old models have been published and efforts have been made to incorporate these data wherever possible. Each chapter deals with tumors of a particular organ or system and describes all neoplasms that have been reported to occur in the organ concerned, using the terminology proposed by WHO for human tumors. The structure adopted for each chapter in the first edition (normal structure of the organ in question, classification, morphology and histology of tumors, incidence of spontaneous tumors, methods of inductions, comparative aspects, illustrations and references) is retained in the new edition. Separate chapters are included in the second edition of this volume on tumors of the nasal cavities and tumors of the salivary and lacrimal glands; in the first edition these were described in one chapter. Likewise, the chapter on tumors of hematopoietic organs is now divided into two independent chapters, one on tumors of the lymphohematopoietic tissue and the other describing histolytic sarcoma. A brief chapter on gallbladder tumors has been added.
Book Synopsis Tumors of the Harderian Gland of Mice, 31 Microslides by :
Download or read book Tumors of the Harderian Gland of Mice, 31 Microslides written by and published by . This book was released on 1984 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Nude Mouse in Oncology Research by : Epie Boven
Download or read book The Nude Mouse in Oncology Research written by Epie Boven and published by CRC Press. This book was released on 2018-01-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Book Synopsis Mouse Models of Human Cancer by : Eric C. Holland
Download or read book Mouse Models of Human Cancer written by Eric C. Holland and published by John Wiley & Sons. This book was released on 2004-08-27 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mice have become the species of choice for modeling the complex interactions between tumor cells and the host environment. Mouse genetics are easily manipulated, and a growing array of technology exists for this purpose. Mouse models allow investigators to better understand causal relationships between specific genetic alterations and tumors, utilize new imaging techniques, and test novel therapies. Recent developments along these lines show great promise for the development of new anti-cancer treatments. Mouse Models of Human Cancer provides researchers and students with a complete resource on the subject, systematically presenting the principles, methodologies, applications, and challenges associated with this exciting field. Offering a survey of the latest research and a description of future areas of interest, this text: Presents real experimental data Describes organ site-specific mouse models Clearly identifies suitable models for further drug testing Critically analyzes current methodologies and their limitations Features numerous recognizable expert contributors Lists key Web sites, reagents, and companies From mouse handling and genetic engineering to preclinical trials, Mouse Models of Human Cancer is a comprehensive guide to using these models and relating them to human disease. Its uniform presentation describes organ-specific models in clinical, imaging, and molecular terms, and lays out the relevant genetics, experimental approaches, histological comparisons with human disease, and conclusions. Combining stellar chapter authors, rich illustrations, and clear, up-to-date coverage, Mouse Models of Human Cancer is an invaluable resource for advanced students and cutting-edge researchers.
Book Synopsis Pathology of Tumours in Laboratory Animals - V.2 - Tumours of the Mouse by : International Agency for Research on Cancer
Download or read book Pathology of Tumours in Laboratory Animals - V.2 - Tumours of the Mouse written by International Agency for Research on Cancer and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tumor Models in Cancer Research by : Beverly A. Teicher
Download or read book Tumor Models in Cancer Research written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2001-11-07 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in animal tumor model research. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene knockout models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.
Book Synopsis Pathology of Tumours in Laboratory Animals: Tumours of the mouse by : International Agency for Research on Cancer
Download or read book Pathology of Tumours in Laboratory Animals: Tumours of the mouse written by International Agency for Research on Cancer and published by . This book was released on 1973 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transgenic Mouse Methods and Protocols by : Marten H. Hofker
Download or read book Transgenic Mouse Methods and Protocols written by Marten H. Hofker and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marten Hofker and Jan van Deursen have assembled a multidisciplinary collection of readily reproducible methods for working with mice, and particularlyfor generating mouse models that will enable us to better understand gene function. Described in step-by-step detail by highly experienced investigators, these proven techniques include new methods for conditional, induced knockout, and transgenic mice, as well as for working with mice in such important research areas as immunology, cancer, and atherosclerosis. Such alternative strategies as random mutagenesis and viral gene transduction for studying gene function in the mouse are also presented.
Book Synopsis Pathology of Tumours in Laboratory Animals by : V. S. Turusov
Download or read book Pathology of Tumours in Laboratory Animals written by V. S. Turusov and published by Oxford University Press, USA. This book was released on 1984-08-01 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Genetically Engineered Mice for Cancer Research by : Jeffrey E. Green
Download or read book Genetically Engineered Mice for Cancer Research written by Jeffrey E. Green and published by Springer Science & Business Media. This book was released on 2011-12-09 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.
Book Synopsis A Symposium on Mammary Tumors in Mice ... by : National Cancer Institute (U.S.)
Download or read book A Symposium on Mammary Tumors in Mice ... written by National Cancer Institute (U.S.) and published by . This book was released on 1945 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transplanted Tumours of Rats and Mice by : D. C. Roberts
Download or read book Transplanted Tumours of Rats and Mice written by D. C. Roberts and published by . This book was released on 1969 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Patient Derived Tumor Xenograft Models by : Rajesh Uthamanthil
Download or read book Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil and published by Academic Press. This book was released on 2016-10-13 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. - Offers guidance on data interpretation and regulatory aspects - Provides useful techniques and strategies for working with PDX models - Includes practical tools and potential pitfalls for best practices - Compiles all knowledge of PDX models research in one resource - Presents the results of first ever global survey on standards of PDX development and usage in academia and industry
Book Synopsis Mouse Models of Cancer by : Robert Eferl
Download or read book Mouse Models of Cancer written by Robert Eferl and published by Humana Press. This book was released on 2015-01-31 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice for research on cancer and other human disorders. The chapters of this book will support scientists in choosing the most suitable mouse models for their research questions. The book provides detailed methodological information for genetic or chemical induction of different types of cancer, histomorphometric cancer analysis, and in vivo imaging, as well as protocols to investigate oncogene addiction, immune surveillance, and hallmarks of cancer such as angiogenesis or metastasis. Four review-like articles provide background information on mouse technologies and histopathologic differences between mouse and human cancers. The mouse models described in individual chapters will fuel the understanding of cancer initiation, immune system roles, tumor angiogenesis, invasion, metastasis, and the relevance of molecular diversity observed among human cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and resourceful, Mouse Models of Cancers: Methods and Protocols, is a valuable laboratory resource for all researchers, from the graduate level upwards, who study cancer and new possibilities for its treatment.
Book Synopsis Pathology of Tumours in Laboratory Animals: Tumours of the mouse by : Vladimir Stanislavovich Turusov
Download or read book Pathology of Tumours in Laboratory Animals: Tumours of the mouse written by Vladimir Stanislavovich Turusov and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
