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Tuberculosis Research And Development
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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes
Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Book Synopsis Tuberculosis Research and Development by : Cindra Feuer
Download or read book Tuberculosis Research and Development written by Cindra Feuer and published by . This book was released on 2007-01-01 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This report is the product of an effort by the Treatment Action Group (TAG) to ascertain the major funders of tuberculosis (TB) research and development (R&D) in 2005, what kinds of research activity they funded, and how much research activity is already taking place. This assessment will help policymakers, funders, researchers, and advocates understand the current state of research on TB, and it provides a baseline for understanding how much TB research funding will need to increase in order to bring TB under control over the next decade. " - p. 6
Book Synopsis Tuberculosis Research and Development by : Cindra Feuer
Download or read book Tuberculosis Research and Development written by Cindra Feuer and published by . This book was released on 2006-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This report is the product of an effort by the Treatment Action Group (TAG) to ascertain the major funders of tuberculosis (TB) research and development (R & D) in 2005, what kinds of research activity they funded, and how much research activity is already taking place. This assessment will help policymakers, funders, researchers, and advocates understand the current state of research on TB, and it provides a baseline for understanding how much TB research funding will need to increase in order to bring TB under control over the next decade."--Page 6.
Book Synopsis Tuberculosis Research and Development by :
Download or read book Tuberculosis Research and Development written by and published by . This book was released on 2008-07 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A global strategy for tuberculosis research and innovation by :
Download or read book A global strategy for tuberculosis research and innovation written by and published by World Health Organization. This book was released on 2020-08-21 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis (TB) is the leading cause of death from a single infectious agent, and one of the leading causes of death from antimicrobial resistance. To reach the milestones of the End TB Strategy, rapid progress must be made towards universal access to existing TB tools and services in the context of universal health coverage and socioeconomic development. At the same time, new technologies must be developed and introduced to make meaningful progress. The Global Strategy for Tuberculosis Research and Innovation will support the efforts of governments and other stakeholders to accelerate TB research and innovation, and improve equitable access to the benefits of research. This document is aimed primarily at Member States, particularly ministries of health, science and technology, finance and education.
Book Synopsis Evidence and research gaps identified during development of policy guidelines for tuberculosis by :
Download or read book Evidence and research gaps identified during development of policy guidelines for tuberculosis written by and published by World Health Organization. This book was released on 2021-12-13 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving the goals and targets of the WHO End TB Strategy requires innovative tools and strategies as well as rapid progress towards universal access. This document summarizes evidence gaps articulated in various WHO tuberculosis TB policy guidance to help steer innovation towards sustainable, desirable, acceptable, and feasible public health interventions required to end TB. It aims to serve as a reference for research policy-makers, funders, civil society and other relevant actors on the urgent TB research priorities for policy guidance.
Book Synopsis Tuberculosis Research and Development by :
Download or read book Tuberculosis Research and Development written by and published by . This book was released on 2009-03 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Disease Control Priorities in Developing Countries by : Dean T. Jamison
Download or read book Disease Control Priorities in Developing Countries written by Dean T. Jamison and published by World Bank Publications. This book was released on 2006-04-02 with total page 1449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.
Author :Russian Academy of Medical Sciences Publisher :National Academies Press ISBN 13 :0309225051 Total Pages :158 pages Book Rating :4.3/5 (92 download)
Book Synopsis The New Profile of Drug-Resistant Tuberculosis in Russia by : Russian Academy of Medical Sciences
Download or read book The New Profile of Drug-Resistant Tuberculosis in Russia written by Russian Academy of Medical Sciences and published by National Academies Press. This book was released on 2011-07-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty--the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. The New Profile of Drug-Resistant Tuberculosis in Russia: A Global and Local Perspective: Summary of a Joint Workshop presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.
Book Synopsis Tuberculosis and the Tubercle Bacillus by : William R. Jacobs, Jr.
Download or read book Tuberculosis and the Tubercle Bacillus written by William R. Jacobs, Jr. and published by John Wiley & Sons. This book was released on 2020-07-15 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can today's innovative practices and molecular tools tame this ancient disease? One third of the world's population is infected with tuberculosis (TB), with about 10 million new cases annually. To combat TB and its agent, Mycobacterium tuberculosis, the World Health Organization launched The End TB Strategy, which aims to slash the suffering and cost of TB by 2035. This makes the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme, an extremely valuable resource for scientists and clinicians. The editors have gathered their colleagues from around the world to present the latest on the molecular biology of M. tuberculosis and related species, the host-pathogen interactions that enable invasion, and the host's immune response to M. tuberculosis infection. The basic, clinical, and translational research presented in this book supports the goals of WHO's End TB Strategy by driving toward the development of effective vaccines, rapid molecular diagnostics, and anti-TB drugs. Creating an effective tuberculosis vaccine. Understand the innate and adaptive immune response to M. tuberculosis infection, its study in established animal models, and how this information is being used to develop new vaccines against TB. Formulating new antituberculosis drugs. Learn the challenges and methods for evaluating new drugs in preclinical trials with a focus on drugs that work against "persisters" and those that act on the electron transport complex and ATP synthase of M. tuberculosis. Overcoming the challenges of diagnosing tuberculosis. Review new diagnostic tools that are simple, rapid, affordable, specific, sensitive, and safe, including molecular-based diagnostic methods such as GeneXpert MTB/RIF. Using molecular, genomic, and bioinformatics tools to understand the biology and evolution of Mycobacterium. Explore current research on the molecular mechanisms that M. tuberculosis uses to evade the immune system, enter a state of nonreplicating persistence, and become reactivated. The second edition of Tuberculosis and the Tubercle Bacillus presents the latest research on a microorganism that is exquisitely well adapted to its human host. This pathogen continues to confound scientists, clinicians, and public health specialists, who will all find much valuable information in this comprehensive set of reviews.
Book Synopsis Nanotechnology Based Approaches for Tuberculosis Treatment by : Prashant Kesharwani
Download or read book Nanotechnology Based Approaches for Tuberculosis Treatment written by Prashant Kesharwani and published by Academic Press. This book was released on 2020-06-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers
Book Synopsis Facing the Reality of Drug-Resistant Tuberculosis in India by : Institute of Medicine
Download or read book Facing the Reality of Drug-Resistant Tuberculosis in India written by Institute of Medicine and published by National Academies Press. This book was released on 2012-08-20 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 8.8 million people fell ill with tuberculosis (TB) in 2010 and 1.4 million died from the disease. Although antibiotics to treat TB were developed in the 1950s and are effective against a majority of TB cases, resistance to these antibiotics has emerged over the years, resulting in the growing spread of multidrug-resistant (MDR) TB. Due to challenges in timely and accurate diagnosis of drug-resistant TB, length and tolerability of treatment regimens, and expense of second-line anti-TB drugs, effectively controlling the disease requires complex public health interventions. The IOM Forum on Drug Discovery, Development, and Translation held three international workshops to gather information from local experts around the world on the threat of drug resistant TB and how the challenges it presents can be met. Workshops were held in South Africa and Russia in 2010. The third workshop was held April 18-19, 2011, in New Delhi, India, in collaboration with the Indian National Science Academy and the Indian Council of Medical Research. The aim of the workshop was to highlight key challenges to controlling the spread of drug-resistant strains of TB in India and to discuss strategies for advancing and integrating local and international efforts to prevent and treat drug-resistant TB. This document summarizes the workshop.
Book Synopsis Situational assessment checklist to guide implementation of the global strategy for tuberculosis research and innovation by :
Download or read book Situational assessment checklist to guide implementation of the global strategy for tuberculosis research and innovation written by and published by World Health Organization. This book was released on 2021-03-23 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research along its full spectrum is critical for developing new tools and strategies for better tuberculosis (TB) prevention, diagnosis, treatment and care and to provide scientific evidence for programmes, practitioners and policy-makers working to alleviate morbidity and mortality from TB. Under the leadership of WHO, a global strategy for TB research and innovation was developed and adopted by Member States in 2020 to advance research and innovation, by translating political commitments made in the Moscow Declaration to End TB (2017) and the political declaration at the United Nations high-level meeting on TB (2018) into concrete actions. The present document is a checklist that allows for a robust analysis of the current situation at country level, to build an evidence base for prioritizing the implementations of the recommendations made in the global strategy through changes in policies, programmes and interventions. It is designed as a reference for ministries of health and other entities responsible for overseeing the implementation of the global strategy.
Book Synopsis Ending Neglect by : Institute of Medicine
Download or read book Ending Neglect written by Institute of Medicine and published by National Academies Press. This book was released on 2000-08-31 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tuberculosis emerged as an epidemic in the 1600s, began to decline as sanitation improved in the 19th century, and retreated further when effective therapy was developed in the 1950s. TB was virtually forgotten until a recent resurgence in the U.S. and around the worldâ€"ominously, in forms resistant to commonly used medicines. What must the nation do to eliminate TB? The distinguished committee from the Institute of Medicine offers recommendations in the key areas of epidemiology and prevention, diagnosis and treatment, funding and organization of public initiatives, and the U.S. role worldwide. The panel also focuses on how to mobilize policy makers and the public to effective action. The book provides important background on the pathology of tuberculosis, its history and status in the U.S., and the public and private response. The committee explains how the U.S. can act with both self-interest and humanitarianism in addressing the worldwide incidence of TB.
Download or read book Tuberculosis written by Wellman Ribón and published by BoD – Books on Demand. This book was released on 2015-07-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress obtained by mycobacteriology in recent years is undeniable with regards to preventing, detecting, and treating cases of tuberculosis, millennial disease that is still present as public health issue worldwide. We present here high-impact research and interest topics related to the application of new methodologies, especially molecular methods for rapid diagnostic such as rapid DST, application of high performance liquid chromatography, molecular epidemiology and molecular diagnostic testing on post mortem. Currently, the constant search for vaccines that prevent the disease is promising through research of the immune response generated by the host towards the bacterium, and the effectiveness that may be achieved from developed vaccines. Another high-impact factor is the one generated by considering tuberculosis as a social disease with an infectious component reflected in research about tuberculosis and human rights. Finally, we present important issues of the pathogen interaction with different hosts. The constant knowledge generation that expands the frontiers of understanding is a key factor for finding solutions and successful activities for public health.
Book Synopsis WHO consolidated guidelines on tuberculosis. Module 4 by : World Health Organization
Download or read book WHO consolidated guidelines on tuberculosis. Module 4 written by World Health Organization and published by World Health Organization. This book was released on 2022-04-30 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 2011 and 2019, WHO has developed and issued evidence-based policy recommendations on the treatment and care of patients with DR-TB. These policy recommendations have been presented in several WHO documents and their associated annexes, including the WHO Consolidated Guidelines on Drug Resistant Tuberculosis Treatment, issued by WHO in March 2019. The policy recommendations in each of these guidelines have been developed by WHO-convened Guideline Development Groups, using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach to summarize the evidence, and formulate policy recommendations and accompanying remarks. The present WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment - Drug-Resistant Tuberculosis Treatment includes a comprehensive set of WHO recommendations for the treatment and care of DR-TB. The document includes two new recommendations, one on the composition of shorter regimens and one on the use of the BPaL regimen (i.e. bedaquiline, pretomanid and linezolid). In addition, the consolidated guidelines include existing recommendations on treatment regimens for isoniazid-resistant TB and MDR/RR-TB, including longer regimens, culture monitoring of patients on treatment, the timing of antiretroviral therapy (ART) in MDR/RR-TB patients infected with the human immunodeficiency virus (HIV), the use of surgery for patients receiving MDR-TB treatment, and optimal models of patient support and care. The guidelines are to be used primarily in national TB programmes, or their equivalents in Ministries of Health, and for other policy-makers and technical organizations working on TB and infectious diseases in public and private sectors and in the community.
Book Synopsis Disease and Mortality in Sub-Saharan Africa by : Dean T. Jamison
Download or read book Disease and Mortality in Sub-Saharan Africa written by Dean T. Jamison and published by World Bank Publications. This book was released on 2006-01-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.
