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Author : Chiok Ling Tan
Publisher :
ISBN 13 :
Total Pages : 374 pages
Book Rating : 4.:/5 (222 download)
Download or read book Transcriptional Regulation of the Mouse Interleukin-5 Gene in T-Lymphocytes written by Chiok Ling Tan and published by . This book was released on 1998 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Peter Francis Bourke
Publisher :
ISBN 13 :
Total Pages : 314 pages
Book Rating : 4.:/5 (223 download)
Download or read book Transcriptional Regulation of the Mouse Interleukin-5 Gene in T Lymphocytes written by Peter Francis Bourke and published by . This book was released on 1993 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jun Wang
Publisher :
ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.:/5 (223 download)
Download or read book Transcriptional Regulation of the Mouse and Human Interleukin-5 Genes in T-lymphocytes written by Jun Wang and published by . This book was released on 2001 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anish D. Singh
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (155 download)
Download or read book Studies on the Transcriptional Regulation of Human Interleukin 5 written by Anish D. Singh and published by . This book was released on 2000 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Cameron Stuart Osborne
Publisher :
ISBN 13 :
Total Pages : 218 pages
Book Rating : 4.:/5 (222 download)
Download or read book Transcriptional Regulation of the GM-CSF Gene in T Lymphocytes written by Cameron Stuart Osborne and published by . This book was released on 1996 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the investigation as to whether the mouse granulocyte-macrophage colony-stimulating factor and interleukin-3 genes are regulated in a similar manner as those of the human, focussing on regulation through an enhancer.
Author : Marc Andrew Thomas
Publisher :
ISBN 13 :
Total Pages : 358 pages
Book Rating : 4.:/5 (222 download)
Download or read book Regulation Studies of the Interleukin-5 Gene in T-lymphocytes written by Marc Andrew Thomas and published by . This book was released on 1999 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fiona Rolfe
Publisher :
ISBN 13 :
Total Pages : 458 pages
Book Rating : 4.:/5 (222 download)
Download or read book Transcriptional and Post-transcriptional Regulation of Human Interleukin 5 Gene Expression written by Fiona Rolfe and published by . This book was released on 1996 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ivana Djuretic
Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.:/5 (542 download)
Download or read book Regulation of Gene Expression in T Lymphocytes by the Transcription Factor Runx3 written by Ivana Djuretic and published by . This book was released on 2009 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: T lymphocytes have served as a model system for studying gene regulation and cell fate decisions in many laboratories over the last two decades. In particular, the differentiation of antigen-inexperienced (naïve) T helper cells upon encounter of antigen has received the most attention, as this process can be very efficiently and accurately recapitulated in vitro. T helper (T H) differentiation results in the acquisition of specialized effector functions (i.e. secretion of cytokines) that enable T helper cells to direct appropriate and effective immune responses against a great diversity of pathogens. Thus, dramatic changes in transcriptional profiles occur during this process resulting in selective activation and silencing of the transcriptional potential of cytokine genes (e.g. activation of interferon-gamma [IFN-[gamma]] and silencing of interleukin-4 [IL-4] during T helper-1 differentiation). In an effort to study the mechanism of silencing of one essential T helper cytokine, IL-4, we discovered a role for the Runx family of transcription factors in T H differentiation.
Author : Jonathan Soboloff
Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Author : James J. Lee
Publisher : Academic Press
ISBN 13 : 012394385X
Total Pages : 679 pages
Book Rating : 4.1/5 (239 download)
Download or read book Eosinophils in Health and Disease written by James J. Lee and published by Academic Press. This book was released on 2012-11-02 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.
Author : Robert A. Stockley
Publisher : Springer Science & Business Media
ISBN 13 : 9783764359683
Total Pages : 220 pages
Book Rating : 4.3/5 (596 download)
Download or read book Molecular Biology of the Lung written by Robert A. Stockley and published by Springer Science & Business Media. This book was released on 1998 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this two-volume work is to provide an update on the use of this powerful technology. As such, the books provide an insight in to the techniques for the non-specialist. Scientists embarking upon st udies in chronic lung disease will find a review of the current status of research. At the same time, the books are useful to clinicians, bo th specialist and academic, and to scientists already involved in the basic aspects of the pathogenesis of lung disease. Both volumes deal w ith basic mechanisms of cell biology, receptors and cellactivation and provide an insight as to how the technology influences our concepts o f pathogenesis and viceversa.
Author : Robert Stockley
Publisher : Birkhäuser
ISBN 13 : 3034887841
Total Pages : 209 pages
Book Rating : 4.0/5 (348 download)
Download or read book Molecular Biology of the Lung written by Robert Stockley and published by Birkhäuser. This book was released on 2013-12-01 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Simon Fillatreau
Publisher : Springer
ISBN 13 : 366243492X
Total Pages : 244 pages
Book Rating : 4.6/5 (624 download)
Download or read book Interleukin-10 in Health and Disease written by Simon Fillatreau and published by Springer. This book was released on 2014-07-08 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.
Author : B. Kyewski
Publisher : Springer Science & Business Media
ISBN 13 : 3540277021
Total Pages : 331 pages
Book Rating : 4.5/5 (42 download)
Download or read book CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential written by B. Kyewski and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-reactive T cells via negative selection in the thymus dominant tolerance exerted by regulatory T cells plays a major role in tolerance imposition and maintenance. Among the various regulatory/suppressive cells hitherto described, CD4+CD25+ regulatory T cells (Treg) and interleukin-10 producing T regulatory 1 (Tr1) cells have been studied in most detail and are the subject of most articles in this issue. Treg, also called "natural" regulatory T cells, will be traced from their intra-thymic origin to the site of their action in peripheral lymphoid organs and tissues. The repertoire of Treg is clearly biased towards recognition of self-antigens, thereby potentially preventing autoimmune diseases such as gastritis and oophoritis. Regulatory T cells, however also control infections, allergies and tolerance to transplanted tissues and this requires their induction in the periphery under conditions which are not yet fully understood. The concept of dominant tolerance, by far not novel, will offer new insights and hopefully tools for the successful treatment of autoimmune diseases, improved cancer immunotherapy and transplant survival. The fulfillment of these high expectations will, however, require their unambiguous identification and a better understanding of their mode of action.
Author :
Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gerard Socie
Publisher : Academic Press
ISBN 13 : 0128134399
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)
Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications
Author : Constantin A. Bona
Publisher : CRC Press
ISBN 13 : 0203305132
Total Pages : 864 pages
Book Rating : 4.2/5 (33 download)
Download or read book Cytokines and Cytokine Receptors written by Constantin A. Bona and published by CRC Press. This book was released on 2003-09-02 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic
