Trajectories Of Genetics

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Trajectories of Genetics

Author : Bernard Dujon
Publisher : John Wiley & Sons
ISBN 13 : 178630533X
Total Pages : 266 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Trajectories of Genetics by : Bernard Dujon

Download or read book Trajectories of Genetics written by Bernard Dujon and published by John Wiley & Sons. This book was released on 2020-06-03 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: As genetics becomes increasingly important in our everyday environment, misinterpretation of its scientific foundation leads to mixed feelings of hope and fear about the potential of its applications. Trajectories of Genetics uncovers the many facets of genetics - from humans to animals, plants, and the microscopic world through more than a century of scientific progress. It summarizes the evolution of ideas as the organization and functioning of genetic material has become clearer. The book analyzes how genetic information – transmitted from generation to generation in nucleic acids – enables the fulfillment of biological functions and the evolution of the living world. It illustrates current developments in many areas: the improvement of species of agronomic interest, an increased understanding of microbial worlds, the management of genetic pathologies and the synthesis of new forms of life.

Trajectories of Genetics

Author : Bernard Dujon
Publisher : John Wiley & Sons
ISBN 13 : 1119720397
Total Pages : 218 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Trajectories of Genetics by : Bernard Dujon

Download or read book Trajectories of Genetics written by Bernard Dujon and published by John Wiley & Sons. This book was released on 2020-04-09 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: As genetics becomes increasingly important in our everyday environment, misinterpretation of its scientific foundation leads to mixed feelings of hope and fear about the potential of its applications. Trajectories of Genetics uncovers the many facets of genetics - from humans to animals, plants, and the microscopic world through more than a century of scientific progress. It summarizes the evolution of ideas as the organization and functioning of genetic material has become clearer. The book analyzes how genetic information transmitted from generation to generation in nucleic acids enables the fulfillment of biological functions and the evolution of the living world. It illustrates current developments in many areas: the improvement of species of agronomic interest, an increased understanding of microbial worlds, the management of genetic pathologies and the synthesis of new forms of life.

Cold-Adapted Organisms

Author : Rosa Margesin
Publisher : Springer Science & Business Media
ISBN 13 : 9783540649731
Total Pages : 432 pages
Book Rating : 4.6/5 (497 download)

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Book Synopsis Cold-Adapted Organisms by : Rosa Margesin

Download or read book Cold-Adapted Organisms written by Rosa Margesin and published by Springer Science & Business Media. This book was released on 1999-05-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major parts of the oceans and lands of our planet are permanently, or temporarily, exposed to temperatures below 10 C. Microorganisms, plants and animals living under these conditions have adapted to their environments in such a way that metabolic processes, reproduction and survival strategies are optimal for their natural biotopes. This book presents the most recent knowledge of the ecology and the physiology of cold-adapted microorganisms, plants and animals, and explains the mechanisms of cold-adaptation on the enzymatic and molecular level, including results from the first crystal structures of enzymes of cold-adapted organisms.

Oedipus Rex in the Genomic Era

Author : Yulia Kovas
Publisher : Springer Nature
ISBN 13 : 1349960489
Total Pages : 241 pages
Book Rating : 4.3/5 (499 download)

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Book Synopsis Oedipus Rex in the Genomic Era by : Yulia Kovas

Download or read book Oedipus Rex in the Genomic Era written by Yulia Kovas and published by Springer Nature. This book was released on 2021-10-30 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the answers to fundamental questions about the human mind and human behaviour with the help of two ancient texts. The first is Oedipus Rex (Oedipus Tyrannus) by Sophocles, written in the 5th century BCE. The second is human DNA, with its origins around 4 billion years ago, and continuously revised by chance and evolution. With Sophocles as a guide, the authors take a journey into the Genomic era, an age marked by ever-expanding insights into the human genome. Over the course of this journey, the book explores themes of free will, fate, and chance; prediction, misinterpretation, and the burden that comes with knowledge of the future; self-fulfilling and self-defeating prophecies; the forces that contribute to similarities and differences among people; roots and lineage; and the judgement of oneself and others. Using Oedipus Rex as its lens, this novel work provides an engaging overview of behavioural genetics that demonstrates its relevance across the humanities and the social and life sciences. It will appeal in particular to students and scholars of genetics, education, psychology, sociology, and law.

A Novel Computational Method for Inferring Dynamic Genetic Regulatory Trajectories

Author : Christopher Campbell Reeder
Publisher :
ISBN 13 :
Total Pages : 77 pages
Book Rating : 4.:/5 (32 download)

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Book Synopsis A Novel Computational Method for Inferring Dynamic Genetic Regulatory Trajectories by : Christopher Campbell Reeder

Download or read book A Novel Computational Method for Inferring Dynamic Genetic Regulatory Trajectories written by Christopher Campbell Reeder and published by . This book was released on 2008 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present a novel method called Time Series Affinity Propagation (TSAP) for inferring regulatory states and trajectories from time series genomic data. This method builds on the Affinity Propagation method of Frey and Dueck [10]. TSAP incorporates temporal constraints to more accurately model the dynamic nature of underlying biological mechanisms. We first apply TSAP to synthetic data and demonstrate its ability to recover underlying structure that is obscured by noise. We then apply TSAP to real data and demonstrate that it provides insight into the relationship between gene expression and histone posttranslational modifications during motor neuron development. In particular, the trajectories taken by the Hox genes through the space of regulatory states are characterized. Understanding the dynamics of Hox regulation is important because the Hox genes play a fundamental role in the establishment of motor neuron sub-type identity during development [6].

Genes, Behavior, and the Social Environment

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101964
Total Pages : 385 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genes, Behavior, and the Social Environment by : Institute of Medicine

Download or read book Genes, Behavior, and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-12-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.

Genetics of Adaptation

Author : Rodney Mauricio
Publisher : Springer Science & Business Media
ISBN 13 : 1402038364
Total Pages : 207 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Genetics of Adaptation by : Rodney Mauricio

Download or read book Genetics of Adaptation written by Rodney Mauricio and published by Springer Science & Business Media. This book was released on 2005-07-20 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.

New Horizons in Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309072964
Total Pages : 225 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis New Horizons in Health by : National Research Council

Download or read book New Horizons in Health written by National Research Council and published by National Academies Press. This book was released on 2001-03-09 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Horizons in Health discusses how the National Institutes of Health (NIH) can integrate research in the social, behavioral, and biomedical sciences to better understand the causes of disease as well as interventions that promote health. It outlines a set of research priorities for consideration by the Office of Behavioral and Social Sciences Research (OBSSR), with particular attention to research that can support and complement the work of the National Institutes of Health. By addressing the range of interactions among social settings, behavioral patterns, and important health concerns, it highlights areas of scientific opportunity where significant investment is most likely to improve nationalâ€"and globalâ€"health outcomes. These opportunities will apply the knowledge and methods of the behavioral and social sciences to contemporary health needs, and give attention to the chief health concerns of the general public.

A Genetic Algorithm for Optimising Inter-planetary Trajectories

Author : Stephen Richardson
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis A Genetic Algorithm for Optimising Inter-planetary Trajectories by : Stephen Richardson

Download or read book A Genetic Algorithm for Optimising Inter-planetary Trajectories written by Stephen Richardson and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

A History of Genetics

Author : Alfred Henry Sturtevant
Publisher : CSHL Press
ISBN 13 : 9780879696078
Total Pages : 190 pages
Book Rating : 4.6/5 (96 download)

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Book Synopsis A History of Genetics by : Alfred Henry Sturtevant

Download or read book A History of Genetics written by Alfred Henry Sturtevant and published by CSHL Press. This book was released on 2001 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the small â€œFly Roomâ€ at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.

Comparable Deployment of Regulatory Genes Across Nematostella Vectensis Developmental Trajectories

Author : Patrick Michael Burton
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.:/5 (297 download)

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Book Synopsis Comparable Deployment of Regulatory Genes Across Nematostella Vectensis Developmental Trajectories by : Patrick Michael Burton

Download or read book Comparable Deployment of Regulatory Genes Across Nematostella Vectensis Developmental Trajectories written by Patrick Michael Burton and published by . This book was released on 2005 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: he starlet sea anemone Nematostella vectensis differs from major developmental models (e.g., zebrafish, fruitfly) in that its adult body plan may arise via four distinct developmental trajectories, (1) embryogenesis, (2) regeneration, (3) polarity reversal and (4) physal pinching. Each trajectory begins with a distinct phenotype and leads to an identical adult morphology. The evolution of multiple reproductive strategies has profound consequences for the ecology and evolution of populations. Asexual reproductive strategies preserve favorable genetic combinations, allowing immediate exploitation of current environments. Sexual reproduction generates new genetic combinations, providing an avenue for adaptation and additional niche exploitation. Based on embryonic expression, Nv-fox and Nv-otx were selected as markers for oral and aboral development, respectively. Five Hox genes were selected as markers for primary axis development. The regulatory genes are expressed in comparable manners (i.e., the same body region and tissue layer) across trajectories. Nv-otx is expressed in the developing physa, Nv-fox in the invaginating mouth, and Hox genes along the primary axis. During embryogenesis, Hox genes are also expressed asymmetrically along the secondary axis, suggesting a role in patterning this axis. This potential alternate role for Hox genes is not observed during alternate trajectories, supporting the discrete and separable nature of these gene networks. Given that identical structures result from expression of identical genes in similar contexts, it is likely that these genes are participating in conserved genetic pathways across trajectories.

Genetics and Genomics of Populus

Author : Stefan Jansson
Publisher : Springer
ISBN 13 : 1441915419
Total Pages : 384 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Genetics and Genomics of Populus by : Stefan Jansson

Download or read book Genetics and Genomics of Populus written by Stefan Jansson and published by Springer. This book was released on 2010-03-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Genomics of Populus provides an indepth description of the genetic and genomic tools and approaches for Populus, examines the biology that has been elucidated using genomics, and looks to the future of this unique model plant. This volume is designed to serve both experienced Populus researchers and newcomers to the field. Contributors to the volume are a blend of researchers, some who have spent most of their research career on Populus and others that have moved to Populus from other model systems. Research on Populus forms a useful complement to research on Arabidopsis. In fact, many plant species found in nature are – in terms of the life history and genetics – more similar to Populus than to Arabidopsis. Thus, the genetic and genomic strategies and tools developed by the Populus community, and showcased in this volume, will hopefully provide inspiration for researchers working in other, less well developed, systems.

A Life Course Perspective on Health Trajectories and Transitions

Author : Claudine Burton-Jeangros
Publisher : Springer
ISBN 13 : 331920484X
Total Pages : 215 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis A Life Course Perspective on Health Trajectories and Transitions by : Claudine Burton-Jeangros

Download or read book A Life Course Perspective on Health Trajectories and Transitions written by Claudine Burton-Jeangros and published by Springer. This book was released on 2015-08-11 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book examines health trajectories and health transitions at different stages of the life course, including childhood, adulthood and later life. It provides findings that assess the role of biological and social transitions on health status over time. The essays examine a wide range of health issues, including the consequences of military service on body mass index, childhood obesity and cardiovascular health, socio-economic inequalities in preventive health care use, depression and anxiety during the child rearing period, health trajectories and transitions in people with cystic fibrosis and oral health over the life course. The book addresses theoretical, empirical and methodological issues as well as examines different national contexts, which help to identify factors of vulnerability and potential resources that support resilience available for specific groups and/or populations. Health reflects the ability of individuals to adapt to their social environment. This book analyzes health as a dynamic experience. It examines how different aspects of individual health unfold over time as a result of aging but also in relation to changing socioeconomic conditions. It also offers readers potential insights into public policies that affect the health status of a population.

The Genetic Lottery

Author : Kathryn Paige Harden
Publisher : Princeton University Press
ISBN 13 : 0691242100
Total Pages : 320 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis The Genetic Lottery by : Kathryn Paige Harden

Download or read book The Genetic Lottery written by Kathryn Paige Harden and published by Princeton University Press. This book was released on 2022-10-11 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative and timely case for how the science of genetics can help create a more just and equal society In recent years, scientists like Kathryn Paige Harden have shown that DNA makes us different, in our personalities and in our health—and in ways that matter for educational and economic success in our current society. In The Genetic Lottery, Harden introduces readers to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society. Reclaiming genetic science from the legacy of eugenics, this groundbreaking book offers a bold new vision of society where everyone thrives, regardless of how one fares in the genetic lottery.

In the Light of Evolution

Author : National Academy of Sciences
Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis In the Light of Evolution by : National Academy of Sciences

Download or read book In the Light of Evolution written by National Academy of Sciences and published by . This book was released on 2007 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.

Behavior Genetics of Temperament and Personality

Author : Kimberly J. Saudino
Publisher : Springer Nature
ISBN 13 : 1071609335
Total Pages : 353 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Behavior Genetics of Temperament and Personality by : Kimberly J. Saudino

Download or read book Behavior Genetics of Temperament and Personality written by Kimberly J. Saudino and published by Springer Nature. This book was released on 2021-03-17 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines behavioral genetic research on temperament and personality from a number of perspectives. It takes a developmental perspective on a number of issues across the lifespan, focusing on personality and temperament. The first section focuses on the development of temperament and personality. Typically this has involved exploring genetic and environmental contributions to phenotypic stability and instability, but more recently there has been research that examines the etiology of intra-individual change/growth trajectories. The second section examines genetic and environmental contributions to the association between temperament and personality and other behaviors. The third and fourth sections discuss genotype-environment correlations and interactions, and introduces the reader to molecular genetics research on temperament and personality. Chapter 11 will discuss the significance of this type of research and Chapter 12 will provide an example of specific line of research exploring genes associated with temperament.

Epigenetic Epidemiology

Author : Karin B. Michels
Publisher : Springer Science & Business Media
ISBN 13 : 9400724942
Total Pages : 450 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Epigenetic Epidemiology by : Karin B. Michels

Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer Science & Business Media. This book was released on 2012-01-03 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!