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Author : David William Lupton
Publisher :
ISBN 13 :
Total Pages : 227 pages
Book Rating : 4.:/5 (271 download)
Download or read book Studies Directed Towards the Assembly of the Binary Vinca Alkaloids written by David William Lupton and published by . This book was released on 2005 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael John Harvey
Publisher :
ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.:/5 (845 download)
Download or read book Towards the Assembly of the Binary Vinca Alkaloids written by Michael John Harvey and published by . This book was released on 2006 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinically important alkaloids (+)-vinblastine (1) and (+)-vincristine (2) both exhibit extraordinary potency as anti-mitotic agents and act by destabilising polymerised tubulin. While the development of a structure-activity-relationship (SAR) profile around these natural products should allow for the identification of the relevant pharmacophore, this task is especially daunting because of the structural complexity of these compounds. Indeed, most analogues of the Vinca alkaloids are obtained through modifications of the natural products rather than being generated de-novo by 'total synthesis'...
Author : Gordon M. Cragg
Publisher : CRC Press
ISBN 13 : 1420039652
Total Pages : 610 pages
Book Rating : 4.4/5 (2 download)
Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen
Author : William I. Taylor
Publisher :
ISBN 13 :
Total Pages : 386 pages
Book Rating : 4.:/5 (319 download)
Download or read book The Vinca Alkaloids written by William I. Taylor and published by . This book was released on 1973 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arnold Brossi
Publisher : Academic Press
ISBN 13 : 0080865615
Total Pages : 261 pages
Book Rating : 4.0/5 (88 download)
Download or read book The Alkaloids: Antitumor Bisindole Alkaloids from Catharanthus roseus (L.) written by Arnold Brossi and published by Academic Press. This book was released on 1990-03-20 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Alkaloids: Antitumor Bisindole Alkaloids from Catharanthus roseus (L.)
Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1681080761
Total Pages : 818 pages
Book Rating : 4.6/5 (81 download)
Download or read book Topics in Anti-Cancer Research written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2015-10-21 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fourth volume of the eBook Series entitled Topics in Anti-Cancer Research. This volume covers new research as well as updated chapters on topics relevant to modern cancer research published in the journal Recent Patents on Anti-Cancer Drug Discovery. Interesting diverse methods, new technologies and fast developing areas in the field of anti-cancer research are presented. The topics included in the present volume will be of great value to clinicians, scientists and R&D experts aiming to learn more about the latest developments and new alternatives for different types of cancer treatment. The use of gold macro rods and ultrasound for cancer treatment with hyperthermia, obesity associated breast cancer, and the role of cytokines and chemokines pathways in studying cancer immunotherapy are discussed. The mechanism of antibody-drug and antibody-toxin conjugates alongwith clinical trials research, significance of transforming growth factor-beta and urokinase type plasminogen activator in tumorigenesis and reverstol studies in oncohematological disorders are also presented. Other important areas covered include the discovery of novel compounds, drugs and chemotherapeutics in the treatment of lung cancer, biological functions of cell surface nucleolin in cancer, polymeric nanosystems and nanosystem applications used for anticancer drug therapy. Recent advances in development of new potent tubulin inhibitors and structures of molecular hybrids and their actions in different cell lines have also been discussed. All these studies focused are supported by recent associated patents The topics covered in this fourth volume will be of immense interest for those researchers and scientists looking for new techniques, targets, drugs, compounds and drug delivery methods for various types of cancer and its control.
Author : Kirsi-Marja Oksman-Caldentey
Publisher : CRC Press
ISBN 13 : 1135562954
Total Pages : 731 pages
Book Rating : 4.1/5 (355 download)
Download or read book Plant Biotechnology and Transgenic Plants written by Kirsi-Marja Oksman-Caldentey and published by CRC Press. This book was released on 2002-08-14 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains case studies illustrating the cell culture production of pigments, flavors, and antineoplastic compounds Plant Biotechnology and Transgenic Plants covers topics that range from food to fragrances to fuel. It includes discussions of technologies and research on the engineering, synthesis, utilization, and control of primary and secondary pl
Author :
Publisher :
ISBN 13 :
Total Pages : 1024 pages
Book Rating : 4.3/5 (555 download)
Download or read book Anticancer Research written by and published by . This book was released on 1990 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sumita Jha
Publisher :
ISBN 13 : 9783319274904
Total Pages : pages
Book Rating : 4.2/5 (749 download)
Download or read book Transgenesis and Secondary Metabolism /. written by Sumita Jha and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Goutam Brahmachari
Publisher : Elsevier
ISBN 13 : 0128212780
Total Pages : 386 pages
Book Rating : 4.1/5 (282 download)
Download or read book Discovery and Development of Anti-Breast Cancer Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-06-24 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area. - Highlights active agents from natural sources for development as novel anti-cancer agents - Features contributions from active researchers and leading experts working in the field - Includes foundational background information on both breast cancer mechanisms and natural product structures to support researchers from different disciplines
Author :
Publisher :
ISBN 13 :
Total Pages : 2668 pages
Book Rating : 4.3/5 (91 download)
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marc Damelin
Publisher : Springer
ISBN 13 : 3319781545
Total Pages : 358 pages
Book Rating : 4.3/5 (197 download)
Download or read book Innovations for Next-Generation Antibody-Drug Conjugates written by Marc Damelin and published by Springer. This book was released on 2018-05-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Author : Se-Kwon Kim
Publisher : Springer
ISBN 13 : 3319071459
Total Pages : 801 pages
Book Rating : 4.3/5 (19 download)
Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Author :
Publisher :
ISBN 13 :
Total Pages : 674 pages
Book Rating : 4.3/5 (555 download)
Download or read book Cancer Research written by and published by . This book was released on 1988 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heinz Lüllmann
Publisher :
ISBN 13 : 9783137817024
Total Pages : 404 pages
Book Rating : 4.8/5 (17 download)
Download or read book Color Atlas of Pharmacology written by Heinz Lüllmann and published by . This book was released on 2000 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : S. William Pelletier
Publisher :
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.E/5 ( download)
Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1983 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Margaret F. Roberts
Publisher : Springer Science & Business Media
ISBN 13 : 1475729057
Total Pages : 492 pages
Book Rating : 4.4/5 (757 download)
Download or read book Alkaloids written by Margaret F. Roberts and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since the late 1970s has a single work presented the biology of this heterogenous group of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the field, presents both the historical use of alkaloids and the latest discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and current medicinal use . Highlights include chapters on the chemical ecology of alkaloids in host-predator interactions, and on the compartmentation of alkaloids synthesis, transport, and storage. Extensive cross-referencing in tabular format makes this volume an excellent reference.
