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Towards Solid Phase Nucleic Acid Hybridization Assays On A Paper Based Platform And Within Channel Microfluidics Using Quantum Dots As Donors In Fluorescence Resonance Energy Transfer
Download Towards Solid Phase Nucleic Acid Hybridization Assays On A Paper Based Platform And Within Channel Microfluidics Using Quantum Dots As Donors In Fluorescence Resonance Energy Transfer full books in PDF, epub, and Kindle. Read online Towards Solid Phase Nucleic Acid Hybridization Assays On A Paper Based Platform And Within Channel Microfluidics Using Quantum Dots As Donors In Fluorescence Resonance Energy Transfer ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Introduction to Biosensors by : Jeong-Yeol Yoon
Download or read book Introduction to Biosensors written by Jeong-Yeol Yoon and published by Springer Science & Business Media. This book was released on 2012-10-28 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors: From Electric Circuits to Immunosensors discusses underlying circuitry of sensors for biomedical and biological engineers as well as biomedical sensing modalities for electrical engineers while providing an applications-based approach to the study of biosensors with over 13 extensive, hands-on labs. The material is presented using a building-block approach, beginning with the fundamentals of sensor design and temperature sensors and ending with more complicated biosensors.
Book Synopsis Electrogenerated Chemiluminescence by : Allen J. Bard
Download or read book Electrogenerated Chemiluminescence written by Allen J. Bard and published by CRC Press. This book was released on 2004-07-20 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first source on this expanding analytical science, this reference explores advances in the instrumentation, design, and application of techniques with electrogenerated chemiluminescence (ECL), examining the use and impact of ECL-based assays in clinical diagnostics, life science research, environmental testing, food and water evaluation, and th
Book Synopsis Nanomaterials for Biosensors by : Bansi D. Malhotra
Download or read book Nanomaterials for Biosensors written by Bansi D. Malhotra and published by William Andrew. This book was released on 2017-10-26 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included. - Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors - Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing - Arranged in a material-by-material way, making it clear how each nanomaterial should be used
Book Synopsis Cadmium Telluride Quantum Dots by : John Donegan
Download or read book Cadmium Telluride Quantum Dots written by John Donegan and published by CRC Press. This book was released on 2013-12-03 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last two decades, semiconductor quantum dots—small colloidal nanoparticles—have garnered a great deal of scientific interest because of their unique properties. Among nanomaterials, CdTe holds special technological importance as the only known II–VI material that can form conventional p–n junctions. This makes CdTe very important for the development of novel optoelectronic devices such as light-emitting diodes, solar cells, and lasers. Moreover, the demand for water-compatible light emitters and the most common biological buffers give CdTe quantum dots fields a veritable edge in biolabeling and bioimaging. Cadmium Telluride Quantum Dots: Advances and Applications focuses on CdTe quantum dots and addresses their synthesis, assembly, optical properties, and applications in biology and medicine. It makes for a very informative reading for anyone involved in nanotechnology and will also benefit those scientists who are looking for a comprehensive account on the current state of quantum dot–related research.
Book Synopsis Angiogenesis Assays by : Carolyn A. Staton
Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Download or read book Paper Based Sensors written by and published by Elsevier. This book was released on 2020-06-11 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paper Based Sensors, Volume 89, the latest release in this comprehensive series that gathers the most important issues relating to the design and application of these cost-effective devices used in many industries, including health and environment diagnostics, safety and security, chemistry, optics, electrochemistry, nanoscience and nanotechnologies, presents the latest updates in the field. Chapters in this new release include Exploring paper as a substrate for electrochemical micro-devices, Paper-based sensors for application in biological compound detection, Printed paper-based (bio)sensors: design, fabrication and applications, Paper-based electrochemical sensing devices, Multifarious aspects of electrochemical paper-based (bio)sensors, Paper Based Biosensors for Clinical and Biomedical Applications, and more.
Book Synopsis Nanomaterials Design for Sensing Applications by : Olena V. Zenkina
Download or read book Nanomaterials Design for Sensing Applications written by Olena V. Zenkina and published by Elsevier. This book was released on 2019-03-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials Design for Sensing Applications examines chemosensors, beginning with molecules that are able to respond to certain stimuli and then showing their assembly and incorporation into sensing materials. The mechanisms of their action for the detection of ions, specific molecules and biostructures, are also covered. A major theme is the affordability of sensors, with particular attention paid to inexpensive and reliable colorimetric sensors that can be read by the naked eye. The book also delves into the development of sensors that utilize existing RFID infrastructure and introduces a novel strategy for the development of self-healing sensing platforms. This book will help readers develop a better understanding of the types of materials used for sensing at the nano level, while also providing an insightful overview on recent advances in this important area. - Demonstrates how the use of nanomaterials allows for the creation of cheaper, more reliable sensors - Shows how metal oxide nanostructures are used as both sensors and supports for embedded organic and organometallic sensing molecules - Explores a novel sensing methodology resulting from the integration of nanostructured sensors into radio frequency identification tags
Book Synopsis Advanced Healthcare Materials by : Ashutosh Tiwari
Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers
Book Synopsis Handbook of Surface Plasmon Resonance by : Richard B. M. Schasfoort
Download or read book Handbook of Surface Plasmon Resonance written by Richard B. M. Schasfoort and published by Royal Society of Chemistry. This book was released on 2017-05-30 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.
Book Synopsis Detection of Non-Amplified Genomic DNA by : Giuseppe Spoto
Download or read book Detection of Non-Amplified Genomic DNA written by Giuseppe Spoto and published by Springer Science & Business Media. This book was released on 2012-07-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.
Book Synopsis Medical Biosensors for Point of Care (POC) Applications by : Roger Narayan
Download or read book Medical Biosensors for Point of Care (POC) Applications written by Roger Narayan and published by Woodhead Publishing. This book was released on 2016-08-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. - Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications - Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications - Includes contributions from leading international researchers with extensive experience in developing medical biosensors - Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care
Book Synopsis Frontiers in Chemical Sensors by : Guillermo Orellana
Download or read book Frontiers in Chemical Sensors written by Guillermo Orellana and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: With their similarity to the organs of the most advanced creatures that inhabit the Earth, sensors are regarded as being the “senses of electronics”: arti?cial eyes and ears that are capable of seeing and hearing beyond the range of - man perception; electronic noses and tongues that can recognise odours and ?avours without a lifetime training; touch that is able not only to feel the texture and temperature of the materials but even to discern their chemical compo- tion. Among the world of chemical sensors, optical devices (sometimes termed “optodes”, from the Greek “the optical way”) have reached a prominent place in those areas where the features of light and of the light-matter interaction show their advantage: contactless or long-distance interrogation, detection sensitivity, analyte selectivity, absence of electrical interference or risks, and lack of analyte consumption, to name just a few. The introduction of optical ?bres and integrated optics has added more value to such sensing since now light can be con?ned and readily carried to dif?cult-to-reach locations, higher information density can be transported, indicator dyes can be immobilised at the distal end or the evanescent ?eld for unique chemical and biochemical sensing (including multiplexed and distributed measurements), optical s- sors can now be subject to mass production and novel sensing schemes have been established (interferometric, surface plasmon resonance, ?uorescence energy transfer, supramolecular recognition . . . ).
Book Synopsis Introduction to Single Cell Omics by : Xinghua Pan
Download or read book Introduction to Single Cell Omics written by Xinghua Pan and published by Frontiers Media SA. This book was released on 2019-09-19 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-cell omics is a progressing frontier that stems from the sequencing of the human genome and the development of omics technologies, particularly genomics, transcriptomics, epigenomics and proteomics, but the sensitivity is now improved to single-cell level. The new generation of methodologies, especially the next generation sequencing (NGS) technology, plays a leading role in genomics related fields; however, the conventional techniques of omics require number of cells to be large, usually on the order of millions of cells, which is hardly accessible in some cases. More importantly, harnessing the power of omics technologies and applying those at the single-cell level are crucial since every cell is specific and unique, and almost every cell population in every systems, derived in either vivo or in vitro, is heterogeneous. Deciphering the heterogeneity of the cell population hence becomes critical for recognizing the mechanism and significance of the system. However, without an extensive examination of individual cells, a massive analysis of cell population would only give an average output of the cells, but neglect the differences among cells. Single-cell omics seeks to study a number of individual cells in parallel for their different dimensions of molecular profile on genome-wide scale, providing unprecedented resolution for the interpretation of both the structure and function of an organ, tissue or other system, as well as the interaction (and communication) and dynamics of single cells or subpopulations of cells and their lineages. Importantly single-cell omics enables the identification of a minor subpopulation of cells that may play a critical role in biological process over a dominant subpolulation such as a cancer and a developing organ. It provides an ultra-sensitive tool for us to clarify specific molecular mechanisms and pathways and reveal the nature of cell heterogeneity. Besides, it also empowers the clinical investigation of patients when facing a very low quantity of cell available for analysis, such as noninvasive cancer screening with circulating tumor cells (CTC), noninvasive prenatal diagnostics (NIPD) and preimplantation genetic test (PGT) for in vitro fertilization. Single-cell omics greatly promotes the understanding of life at a more fundamental level, bring vast applications in medicine. Accordingly, single-cell omics is also called as single-cell analysis or single-cell biology. Within only a couple of years, single-cell omics, especially transcriptomic sequencing (scRNA-seq), whole genome and exome sequencing (scWGS, scWES), has become robust and broadly accessible. Besides the existing technologies, recently, multiplexing barcode design and combinatorial indexing technology, in combination with microfluidic platform exampled by Drop-seq, or even being independent of microfluidic platform but using a regular PCR-plate, enable us a greater capacity of single cell analysis, switching from one single cell to thousands of single cells in a single test. The unique molecular identifiers (UMIs) allow the amplification bias among the original molecules to be corrected faithfully, resulting in a reliable quantitative measurement of omics in single cells. Of late, a variety of single-cell epigenomics analyses are becoming sophisticated, particularly single cell chromatin accessibility (scATAC-seq) and CpG methylation profiling (scBS-seq, scRRBS-seq). High resolution single molecular Fluorescence in situ hybridization (smFISH) and its revolutionary versions (ex. seqFISH, MERFISH, and so on), in addition to the spatial transcriptome sequencing, make the native relationship of the individual cells of a tissue to be in 3D or 4D format visually and quantitatively clarified. On the other hand, CRISPR/cas9 editing-based In vivo lineage tracing methods enable dynamic profile of a whole developmental process to be accurately displayed. Multi-omics analysis facilitates the study of multi-dimensional regulation and relationship of different elements of the central dogma in a single cell, as well as permitting a clear dissection of the complicated omics heterogeneity of a system. Last but not the least, the technology, biological noise, sequence dropout, and batch effect bring a huge challenge to the bioinformatics of single cell omics. While significant progress in the data analysis has been made since then, revolutionary theory and algorithm logics for single cell omics are expected. Indeed, single-cell analysis exert considerable impacts on the fields of biological studies, particularly cancers, neuron and neural system, stem cells, embryo development and immune system; other than that, it also tremendously motivates pharmaceutic RD, clinical diagnosis and monitoring, as well as precision medicine. This book hereby summarizes the recent developments and general considerations of single-cell analysis, with a detailed presentation on selected technologies and applications. Starting with the experimental design on single-cell omics, the book then emphasizes the consideration on heterogeneity of cancer and other systems. It also gives an introduction of the basic methods and key facts for bioinformatics analysis. Secondary, this book provides a summary of two types of popular technologies, the fundamental tools on single-cell isolation, and the developments of single cell multi-omics, followed by descriptions of FISH technologies, though other popular technologies are not covered here due to the fact that they are intensively described here and there recently. Finally, the book illustrates an elastomer-based integrated fluidic circuit that allows a connection between single cell functional studies combining stimulation, response, imaging and measurement, and corresponding single cell sequencing. This is a model system for single cell functional genomics. In addition, it reports a pipeline for single-cell proteomics with an analysis of the early development of Xenopus embryo, a single-cell qRT-PCR application that defined the subpopulations related to cell cycling, and a new method for synergistic assembly of single cell genome with sequencing of amplification product by phi29 DNA polymerase. Due to the tremendous progresses of single-cell omics in recent years, the topics covered here are incomplete, but each individual topic is excellently addressed, significantly interesting and beneficial to scientists working in or affiliated with this field.
Book Synopsis Aptamers for Analytical Applications by : Yiyang Dong
Download or read book Aptamers for Analytical Applications written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2019-02-11 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide that puts the focus on method developments and applications in aptamers In recent years, aptamer-based systems have been developed for a wide-range of analytical and medical applications. Aptamers for Analytical Applications offers an introduction to the topic, outlines the common protocols for aptamer synthesis, as well as providing information on the different optimization strategies that can obtain higher affinities to target molecules. The contributors?noted experts on the topic?provide an in-depth review of the characterization of aptamer-target molecule interaction and immobilization strategies and discuss the developments of methods for all the relevant applications. The book outlines different schemes to efficiently immobilize aptamers on substrates as well as summarizing the characterization methods for aptamer-ligand complexes. In addition, aptamer-based colorimetric, enzyme-linked, fluorescent, electrochemical, lateral flow and non-labeling analytical methods are presented. The book also reflects state-of-the-art and emerging applications of aptamer-based methods. This important resource: -Provides a guide to aptamers which provide highly specific and sensitive molecular recognition, with affinities in the range of antibodies and are much cheaper to produce -Offers a discussion of the analytical method developments and improvements with established systems and beyond -Offers a comprehensive guide to all the relevant application areas -Presents an authoritative book from contributors who are noted experts in the field Written for analytical chemists, biochemists, analytical researchers, Aptamers for Analytical Applications is a comprehensive book that adopts a methodological point of view to the important aspects of aptamer generation and modification with a strong emphasis on method developments for relevant applications.
Book Synopsis Smart Biosensor Technology by : George K. Knopf
Download or read book Smart Biosensor Technology written by George K. Knopf and published by CRC Press. This book was released on 2020-06-30 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition covers the fundamentals of smart biosensor technology, issues related to material design and selection, enabling methods of biosensor fabrication, bioelectronics and neuronal network micro-arrays, and applications that include pathogen detection, toxicity monitoring and lab-on-chip (LoC) technologies.
Book Synopsis FRET and FLIM Techniques by : Theodorus W. J. Gadella
Download or read book FRET and FLIM Techniques written by Theodorus W. J. Gadella and published by Elsevier. This book was released on 2011-07-29 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the techniques Förster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.
Book Synopsis Semiconductor Nanomaterials by : Challa S. S. R. Kumar
Download or read book Semiconductor Nanomaterials written by Challa S. S. R. Kumar and published by John Wiley & Sons. This book was released on 2010-04-05 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 6 - Semiconductor Nanomaterials
