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Tissue Barriers In Disease Injury And Regeneration
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Book Synopsis Tissue Barriers in Disease, Injury and Regeneration by : Nikolai V. Gorbunov
Download or read book Tissue Barriers in Disease, Injury and Regeneration written by Nikolai V. Gorbunov and published by Elsevier. This book was released on 2021-06-23 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium
Book Synopsis Tissue Barriers in Disease, Injury and Regeneration by : Nikolai V. Gorbunov
Download or read book Tissue Barriers in Disease, Injury and Regeneration written by Nikolai V. Gorbunov and published by Elsevier. This book was released on 2021-06-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium
Book Synopsis Pathologic Basis of Veterinary Disease by : M. Donald McGavin
Download or read book Pathologic Basis of Veterinary Disease written by M. Donald McGavin and published by Mosby. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th edition of this textbook, now in full color, presents both general pathology and special pathology in one comprehensive resource. Coverage includes a brief review of basic principles related to anatomy, structure and function, followed by congenital and functional abnormalities and discussions of viral, bacterial, and parasitic infections and neoplasia. Logically organized chapters discuss normal functions of the body system, followed by pathologic conditions found in domestic and companion animals. While focusing primarily on diseases in North America, the text also includes pathologic conditions found in other parts of the world, as well as those being brought into this country, such as West Nile virus, through the importation of cattle, sheep, and other animals. Contributors are recognized in their area of expertise and are well known in research and education. Now in full color throughout with vivid new illustrations that clarify difficult concepts. Includes six new chapters covering general pathology that discuss topics such as cellular and tissue responses to injury, vascular disorders, inflammation, and tumor biology. All chapters emphasize mechanisms of disease (organ, tissue, cell, and molecular injury). Features sequential presentations of disease processes (portal of entry * target cells * cellular injury * visual appearance of injury * resolution of injury * clinical outcomes). Emphasizes portals of entry for microbes and injurious agents. Focuses on defense mechanisms against microbes and injurious agents.
Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger
Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Book Synopsis Muscle Regeneration by : Alexander Mauro
Download or read book Muscle Regeneration written by Alexander Mauro and published by Raven Press (ID). This book was released on 1979 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis In Situ Tissue Regeneration by : Sang Jin Lee
Download or read book In Situ Tissue Regeneration written by Sang Jin Lee and published by Academic Press. This book was released on 2016-07-17 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry
Book Synopsis Indwelling Neural Implants by : William M. Reichert
Download or read book Indwelling Neural Implants written by William M. Reichert and published by CRC Press. This book was released on 2007-12-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.
Book Synopsis Textbook of Neural Repair and Rehabilitation by : Michael E. Selzer
Download or read book Textbook of Neural Repair and Rehabilitation written by Michael E. Selzer and published by Cambridge University Press. This book was released on 2014 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.
Book Synopsis Regenerative Pharmacology by : George J. Christ
Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.
Book Synopsis Frontiers in Tissue Engineering by : C.W. Patrick
Download or read book Frontiers in Tissue Engineering written by C.W. Patrick and published by Elsevier. This book was released on 1998-02-20 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.
Book Synopsis Ontogeny and Phylogeny of Brain Barrier Mechanisms by : Norman R Saunders
Download or read book Ontogeny and Phylogeny of Brain Barrier Mechanisms written by Norman R Saunders and published by Frontiers Media SA. This book was released on 2016-04-15 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain functions within an internal environment that is determined and controlled by morphological structures and cellular mechanisms present at interfaces between the brain and the rest of the body. In vertebrates these interfaces are across cerebral blood vessels (blood-brain barrier) choroid plexuses (blood-cerebrospinal fluid barrier) and pia-arachnoid. There is a CSF-brain barrier in the neuroepithelium lining the ventricular system that is only present in embryos. There is now substantial evidence that many brain barrier mechanisms develop early and that in some cases they are functionally more active and even more specialized compared to adult barriers. Therefore barriers in developing brain should be viewed as adapted appropriately for the growing brain and not, as is still widely believed, immature. Considerable advances in our understanding of these barrier mechanisms have come from studies of the developing brain and invertebrates. A striking aspect, to be highlighted in this special edition, is that many of the molecular mechanisms in these very diverse species are similar despite differences in the cellular composition of the interfaces. This Frontiers Topic comprises articles in three sections: Original studies, Reviews and Myths & Misconceptions. Original articles provide new information on molecular and cellular barrier mechanisms in developing brains of primates, including human embryos (Brøchner et al., Ek et al., Errede et al.), rodents (Bauer et al., Liddelow, Strazielle & Ghersi-Egea, Saunders et al., Whish et al.), chick (Bueno et al.) and zebrafish (Henson et al.) as well as studies in drosophila (Hindle & Bainton, De Salvo et al., Limmer et al.). The Reviews section includes evolutionary perspectives of the blood-brain and blood-CSF barriers (Bueno et al., Bill & Korzh). There are also detailed reviews of the current state of understanding of different interfaces and their functional mechanisms in developing brain (Bauer et al., Strazielle & Gjersi-Egea, Liddelow, Richardson et al., Errede et al., Henson et al., Brøchner et al) and in invertebrates (Hindle & Bainton, De Salvo et al., Limmer et al). Different aspects of the relationship between properties of the internal environment of the brain and its development are discussed. (Stolp & Molnar, Johansson, Prasongchean et al.). A neglected area, namely barriers over the surface of the brain during development is also covered (Brøchner et al.). Clinically related perspectives on barrier disruption in neonatal stroke are provided by Kratzer et al. and other aspects of dysfunction by Morretti et al. and by Palmeta et al. on the continuing problem of bilirubin toxicity. Progress in this field is hampered by many prevailing myths about barrier function, combined with methodologies that are not always appropriately selected or interpreted. These is covered in the Misconceptions, Myths and Methods section, including historical aspects and discussion of the paracellular pathway, a central dogma of epithelial and endothelial biology (Saunders et al.) and a review of markers used to define brain barrier integrity in development and in pathological conditions (Saunders et al.). Use of inappropriate markers has caused considerable confusion and unreliable interpretation in many published studies. Torbett et al deal with the complexities of the new field of applying proteomics to understanding blood-brain barrier properties as do Huntley at al with respect to applying modern high throughput gene expression methods (Huntley et al.). The Editorial summarizes the contributions from all authors. This includes mention of some the main unanswered but answerable questions in the field and what the impediments to progress may be.
Book Synopsis Regenerative Medicine and Plastic Surgery by : Dominik Duscher
Download or read book Regenerative Medicine and Plastic Surgery written by Dominik Duscher and published by Springer Nature. This book was released on 2019-11-26 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the current research concepts and the emerging technologies in the field of stem cells and tissue engineering. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner. Divided into five parts, the book opens with a description of the elements of regenerative medicine including definitions, basic principles of soft and bone tissue regeneration, biomaterials and scaffolds. Current research concepts are explored in the second part of this book, for example mechanotransduction and the utility of extracellular vesicles. In the third part, the editors present the emerging technologies and highlight the novel perspectives on bionic reconstruction and biomimetics in surgery and regenerative medicine. Part four deals with translational aspects including practical information on moving scientific findings from bench to bedside. The final part then describes in detail applications in clinical plastic surgery. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "In your hands is a comprehensive encyclopedia of two rapidly converging fields. Drs Duscher and Shiffman have done an outstanding job of highlighting the interdependent relationship between plastic surgery and regenerative medicine. Ultimately, this is to the benefit of both fields." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Book Synopsis Biomaterials in Tissue Engineering and Regenerative Medicine by : Birru Bhaskar
Download or read book Biomaterials in Tissue Engineering and Regenerative Medicine written by Birru Bhaskar and published by Springer Nature. This book was released on 2021-04-29 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
Book Synopsis Fundamentals of Tissue Engineering and Regenerative Medicine by : Ulrich Meyer
Download or read book Fundamentals of Tissue Engineering and Regenerative Medicine written by Ulrich Meyer and published by Springer Science & Business Media. This book was released on 2009-02-11 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.
Book Synopsis Degeneration and Regeneration in the Nervous System by : Norman Saunders
Download or read book Degeneration and Regeneration in the Nervous System written by Norman Saunders and published by CRC Press. This book was released on 2003-09-02 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.
Download or read book Epigenetics and Regeneration written by and published by Academic Press. This book was released on 2019-05-24 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. Provides a foundational overview of epigenetics in regenerative medicine Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine
