Therapeutic Applications Of Cell Microencapsulation

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Therapeutic Applications of Cell Microencapsulation

Author : Jose Luis Pedraz
Publisher : Springer Science & Business Media
ISBN 13 : 1441957863
Total Pages : 167 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Therapeutic Applications of Cell Microencapsulation by : Jose Luis Pedraz

Download or read book Therapeutic Applications of Cell Microencapsulation written by Jose Luis Pedraz and published by Springer Science & Business Media. This book was released on 2010-12-31 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advancement of science is ever more contingent upon the interaction of experts vast amount of scientific information being gathered every day that exceeds the ability of any one scientist to acquire. As an illustration of the frantic pace of scientific disc- more acute in the case of scientific fields at the interface of different and seemingly distant areas of study. Amidst these, the field of cell encapsulation brings together an array of diverse disciplines such as molecular biology and biopolymers, gene therapy and inorganic membranes, stem cell biology and physicochemistry, immunology and nanotechnology. Clearly, such range of topics is too broad for any individual scientist the state-of-the-art in the field of cell encapsulation. At the core of this technology, there is an interaction of physicochemical and biological elements forming three distinct layers of complexity. First, the chemistry of the biopolymer dictates the degree of protein adsorption, vascularization, tox- ity and biocompatibility of the microcapsules. Advances in biopolymer science are providing solutions to overcome existing challenges and to improve microcapsules as delivery vehicles. Second, the choice of cells, and more precisely the plethora of in determining the immune response elicited by the host to implanted microcapsules.

Cell Microencapsulation

Author : Emmanuel C. Opara
Publisher : Humana
ISBN 13 : 9781493963621
Total Pages : 0 pages
Book Rating : 4.9/5 (636 download)

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Book Synopsis Cell Microencapsulation by : Emmanuel C. Opara

Download or read book Cell Microencapsulation written by Emmanuel C. Opara and published by Humana. This book was released on 2016-10-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a unique forum to review cell microencapsulation in a broad sense by exploring various cell types that have been encapsulated for different purposes, different approaches and devices used for microencapsulation, the biomaterials used in cell microencapsulation, the challenges to the technology, and the current status of its application in different clinical situations. This book is divided in five sections: Section I is an introductory part that discusses historical developments of the technology and its current challenges, as well as the various applications of cell microencapsulation; Section II discusses the main approaches and devices currently used in cell microencapsulation; Section III presents an overview of the various polymeric materials currently in use for cell microencapsulation and the enabling technologies to either monitor or enhance encapsulated cell function; Section IV gives specific examples of the methods used to encapsulate various cell types; and Section V provides an overview of the different clinical situations in which cell microencapsulation has been applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Cell Microencapsulation: Methods and Protocols is a valuable reference for researchers, engineers, clinicians, and other healthcare professionals, as well as food technologists who will find detailed descriptions of methods for the microencapsulation of specific cell types and their current of potential clinical and industrial applications. This volume also includes detailed information about the design and manufacture of different devices including large-scale production devices for use in cell microencapsulation.

Nano- and Microencapsulation

Author : Nedal Abu-Thabit
Publisher : BoD – Books on Demand
ISBN 13 : 1839683481
Total Pages : 292 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Nano- and Microencapsulation by : Nedal Abu-Thabit

Download or read book Nano- and Microencapsulation written by Nedal Abu-Thabit and published by BoD – Books on Demand. This book was released on 2021-01-27 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano- or micro-encapsulation is used in many different fields and industries, including pharmaceuticals, cosmetics, food, and agrochemicals. It offers advantages for various applications, especially drug delivery. Nano-encapsulation can help extend and control the release of drugs as well as increase drug bioavailability and efficacy. It improves the precision of targeted drug delivery and allows for fabricating nano-encapsulated drugs for diagnostic and theranaostic applications. This book covers recent advances in fabricating nano-/micro-capsules using natural carriers for therapeutic and diagnostic drug delivery applications as well as rheology and formulations of micro-emulsions for diverse applications. This book is essential for scientists and researchers with diverse backgrounds in chemistry, engineering, material sciences, pharmaceuticals, and drug delivery.

Bioencapsulation of Living Cells for Diverse Medical Applications

Author : Eva Maria Brandtner
Publisher : Bentham Science Publishers
ISBN 13 : 1608057208
Total Pages : 195 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Bioencapsulation of Living Cells for Diverse Medical Applications by : Eva Maria Brandtner

Download or read book Bioencapsulation of Living Cells for Diverse Medical Applications written by Eva Maria Brandtner and published by Bentham Science Publishers. This book was released on 2013-05-31 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioencapsulation (or microencapsulation) of cells and their implantation into a body of immunoprotected cells allows researchers to revive a missing or defective function in the cells. Microencapsulated cells have reached the clinic where they have been shown to be safe and efficacious in numerous clinical trials. Cell types that have been encapsulated for therapeutic purposes include hybridomas, islet cells, "platform" cell lines e.g. HEK293 and CHO cells as well as an increasing focus on the encapsulation of stem cells. This e-book explains the different methods used for achieving cell bioencapsulation based on different polymers e.g. alginate, cellulose sulphate and agarose. Other chapters in this book subsequently describe the use of cell encapsulation in cancer therapy to improve on existing chemotherapies by reducing doses and thus side effects while increasing efficacy for long term in vivo production of (i) tumoricidal or virus neutralising antibodies, (ii) insulin to achieve a self regulating treatment for diabetes and (iii) neuron nurturing factors to treat CNS diseases such as epilepsy, disorders like Parkinson's disease, Alzheimer, Amyotrophic lateral sclerosis, Huntington's disease and pathologies caused by trauma and/or ischemic processes. The book also includes a chapter reviewing the genetic engineering of cells to allow controlled production of biotherapeutics from encapsulated cells. This is a unique and timely book which brings together contributions from some of the leading researchers in the field of cell encapsulation. Interested readers are provided an overview of the exciting developments and clinical experiences of researchers with cell bioencapsulation.

Cell Microencapsulation

Author : Emmanuel C. Opara
Publisher : Humana
ISBN 13 : 9781493981779
Total Pages : 366 pages
Book Rating : 4.9/5 (817 download)

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Book Synopsis Cell Microencapsulation by : Emmanuel C. Opara

Download or read book Cell Microencapsulation written by Emmanuel C. Opara and published by Humana. This book was released on 2018-06-08 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a unique forum to review cell microencapsulation in a broad sense by exploring various cell types that have been encapsulated for different purposes, different approaches and devices used for microencapsulation, the biomaterials used in cell microencapsulation, the challenges to the technology, and the current status of its application in different clinical situations. This book is divided in five sections: Section I is an introductory part that discusses historical developments of the technology and its current challenges, as well as the various applications of cell microencapsulation; Section II discusses the main approaches and devices currently used in cell microencapsulation; Section III presents an overview of the various polymeric materials currently in use for cell microencapsulation and the enabling technologies to either monitor or enhance encapsulated cell function; Section IV gives specific examples of the methods used to encapsulate various cell types; and Section V provides an overview of the different clinical situations in which cell microencapsulation has been applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Cell Microencapsulation: Methods and Protocols is a valuable reference for researchers, engineers, clinicians, and other healthcare professionals, as well as food technologists who will find detailed descriptions of methods for the microencapsulation of specific cell types and their current of potential clinical and industrial applications. This volume also includes detailed information about the design and manufacture of different devices including large-scale production devices for use in cell microencapsulation.

Cell Encapsulation Technology and Therapeutics

Author : Willem_M. Kühtreiber
Publisher : Springer Science & Business Media
ISBN 13 : 1461215862
Total Pages : 457 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Cell Encapsulation Technology and Therapeutics by : Willem_M. Kühtreiber

Download or read book Cell Encapsulation Technology and Therapeutics written by Willem_M. Kühtreiber and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept into practice. In 1980, Lim and Sun from Connaught Laboratories reported on the successful implantation of poly-I-Iysine-alginate encapsu lated rat islets into a foreign host. [Lim and Sun, Science 210:908-909, 1980]. Now many groups around the world are making tremendous progress in the encapsulation of a multitude of cell types. Kiihtreiber, Lanza, and Chick have invited many cell encapsulation groups from around the world to contribute to this book. The result is a very useful reference book in this rapidly growing area. With so many excellent au thors describing in detail the different areas of cell encapsulation, my role here will be to briefly discuss a few points.

Applications of Cell Immobilisation Biotechnology

Author : Viktor Nedovic
Publisher : Springer Science & Business Media
ISBN 13 : 140203363X
Total Pages : 556 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Applications of Cell Immobilisation Biotechnology by : Viktor Nedovic

Download or read book Applications of Cell Immobilisation Biotechnology written by Viktor Nedovic and published by Springer Science & Business Media. This book was released on 2006-04-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell immobilisation biotechnology is a multidisciplinary area, shown to have an important impact on many scientific subdisciplines – including biomedicine, pharmacology, cosmetology, food and agricultural sciences, beverage production, industrial waste treatment, analytical applications, biologics production. "Cell Immobilisation Biotechnology" is an outcome of the editors’ intention to collate the extensive and widespread information on fundamental aspects and applications of immobilisation/encapsulation biotechnology into a comprehensive reference work and to provide an overview of the most recent results and developments in this domain. "Cell Immobilisation Biotechnology" is divided into the two book volumes, FOBI 8A and FOBI 8B. The FOBI 8A volume, Fundamentals of Cell Immobilisation Biotechnology, is dedicated to fundamental aspects of cell immobilisation while the present volume, FOBI 8B, Applications of Cell Immobilisation Biotechnology, deals with diverse applications of this technology.

Stem Cell Bioengineering And Tissue Engineering Microenvironment

Author : Satya Prakash
Publisher : World Scientific
ISBN 13 : 9814468967
Total Pages : 569 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Stem Cell Bioengineering And Tissue Engineering Microenvironment by : Satya Prakash

Download or read book Stem Cell Bioengineering And Tissue Engineering Microenvironment written by Satya Prakash and published by World Scientific. This book was released on 2011-07-19 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.

Cellular Transplantation

Author : Craig Halberstadt
Publisher : Elsevier
ISBN 13 : 0080469043
Total Pages : 699 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Cellular Transplantation by : Craig Halberstadt

Download or read book Cellular Transplantation written by Craig Halberstadt and published by Elsevier. This book was released on 2011-10-10 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. Provides detailed description of clinical trials in cell transplantation Review of current therapeutic approaches Coverage of the broad range of diseases addressed by cell therapeutics Discussion of stem cell biology and its role in transplantation

Hepatocyte Transplantation

Author : Anil Dhawan
Publisher : Humana Press
ISBN 13 : 9781588298836
Total Pages : 0 pages
Book Rating : 4.2/5 (988 download)

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Book Synopsis Hepatocyte Transplantation by : Anil Dhawan

Download or read book Hepatocyte Transplantation written by Anil Dhawan and published by Humana Press. This book was released on 2009-01-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its efficacy in animal models, cellular therapy using human hepatocytes is being evaluated worldwide as an alternative to organ transplantation in patients with liver-based metabolic disease and acute liver failure. In Hepatocyte Transplantation: Methods and Protocols, an international panel of experts provide up-to-date laboratory and clinical techniques covering the many key areas necessary for successful transplantation, such as cryopreservation, quality assurance, detection of cell engraftment, and the future of the field with the development of foetal hepatoblasts and stem cell derived hepatocytes. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters in this volume present brief introductions to the material, lists of the necessary materials and reagents, readily reproducible, step-by-step laboratory protocols, and Notes sections which highlight tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Hepatocyte Transplantation: Methods and Protocols is an ideal guide for researchers setting out in the rapidly progressing field of hepatocyte transplantation, as well as those who already have experience with this new therapy for liver disease.

Cell Encapsulation Technology and Therapeutics

Author : Willem M. Kühtreiber
Publisher :
ISBN 13 : 9783764340100
Total Pages : 450 pages
Book Rating : 4.3/5 (41 download)

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Book Synopsis Cell Encapsulation Technology and Therapeutics by : Willem M. Kühtreiber

Download or read book Cell Encapsulation Technology and Therapeutics written by Willem M. Kühtreiber and published by . This book was released on 1999 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encapsulated cells offer enormous potential for the treatment of human disease. This work includes detailed descriptions of chemical properties of encapsulation materials, purification, biocompatibility issues and experimental protocols.

Encapsulation Technologies for Active Food Ingredients and Food Processing

Author : N.J. Zuidam
Publisher : Springer Science & Business Media
ISBN 13 : 1441910085
Total Pages : 402 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Encapsulation Technologies for Active Food Ingredients and Food Processing by : N.J. Zuidam

Download or read book Encapsulation Technologies for Active Food Ingredients and Food Processing written by N.J. Zuidam and published by Springer Science & Business Media. This book was released on 2009-10-30 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumers prefer food products that are tasty, healthy, and convenient. Encapsulation is an important way to meet these demands by delivering food ingredients at the right time and right place. For example, encapsulates may allow flavor retention, mask bad tasting or bad smelling components, stabilize food ingredients, and increase their bioavailability. Encapsulation may also be used to immobilize cells or enzymes in the production of food materials or products, such as fermentation or metabolite production. This book provides a detailed overview of the encapsulation technologies available for use in food products, food processing, and food production. The book aims to inform those who work in academia or R&D about both the delivery of food compounds via encapsulation and food processing using immobilized cells or enzymes. The structure of the book is according to the use of encapsulates for a specific application. Emphasis is placed on strategy, since encapsulation technologies may change. Most chapters include application possibilities of the encapsulation technologies in specific food products or processes. The first part of the book reviews general technologies, food-grade materials, and characterization methods for encapsulates. The second part discusses encapsulates of active ingredients (e.g., aroma, fish oil, minerals, vitamins, peptides, proteins, probiotics) for specific food applications. The last part describes immobilization technologies of cells and enzymes for use within food fermentation processes (e.g., beer, wine, dairy, meat), and food production (e.g., sugar conversion, production of organic acids or amino acids, hydrolysis of triglycerides). Edited by two leading experts in the field, Encapsulation Technologies for Food Active Ingredients and Food Processing will be a valuable reference source for those working in the academia or food industry. The editors work in both industry or academia, and they have brought together in this book contributions from both fields.

Fundamentals of Cell Immobilisation Biotechnology

Author : Viktor Nedovic
Publisher : Springer Science & Business Media
ISBN 13 : 9401716382
Total Pages : 542 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Fundamentals of Cell Immobilisation Biotechnology by : Viktor Nedovic

Download or read book Fundamentals of Cell Immobilisation Biotechnology written by Viktor Nedovic and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Immobilisation Biotechnology Biotechnology is divided into two volumes. The first volume is dedicated to fundamental aspects of cell immobilisation while the second volume deals with the diverse applications of this technology. The first volume, Fundamentals of Cell Immobilisation Biotechnology, comprises 26 chapters arranged into four parts: Materials for cell immobilisation/encapsulation, Methods and technologies for cell immobilisation/encapsulation, Carrier characterisation and bioreactor design, and Physiology of immobilised cells: techniques and mathematical modelling.

Microencapsulation for Therapeutic Applications

Author : Nikhil Dhoot
Publisher :
ISBN 13 :
Total Pages : 446 pages
Book Rating : 4.:/5 (52 download)

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Book Synopsis Microencapsulation for Therapeutic Applications by : Nikhil Dhoot

Download or read book Microencapsulation for Therapeutic Applications written by Nikhil Dhoot and published by . This book was released on 2002 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immobilization of Enzymes and Cells

Author : Jose M. Guisan
Publisher : Humana
ISBN 13 : 9781071602171
Total Pages : 495 pages
Book Rating : 4.6/5 (21 download)

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Book Synopsis Immobilization of Enzymes and Cells by : Jose M. Guisan

Download or read book Immobilization of Enzymes and Cells written by Jose M. Guisan and published by Humana. This book was released on 2021-01-29 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition volume expands on the previous editions with new insights on important aspects to take into accounting when immobilizing enzymes and cells, illustrating outstanding examples that support those aspects, and exploring ways to fabricate and characterize heterogeneous biocatalysts including both immobilized enzymes and cells. The transformation of soluble and usually instable enzymes into heterogeneous and highly stable biocatalysts is strongly emphasized. The chapters in this book cover topics such as the importance of enzyme orientation on the support surface; application and characterization of immobilized enzymes; different functionalization chemistries for the modulation of the immobilized enzyme properties; co-immobilization of multi-enzyme systems; new analytical techniques for the characterization of heterogeneous biocatalysts; protocols for cell entrapment in alginate; preparation and characterization of biofilms; and cell encapsulation technologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Immobilization of Enzymes and Cells: Methods and Protocols, Fourth Edition is a valuable resource for researchers interested in expanding their knowledge of this developing field.

Silk-based Drug Delivery Systems

Author : Elia Bari
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017722
Total Pages : 243 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Silk-based Drug Delivery Systems by : Elia Bari

Download or read book Silk-based Drug Delivery Systems written by Elia Bari and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Biomaterials from Nature for Advanced Devices and Therapies

Author : Nuno M. Neves
Publisher : John Wiley & Sons
ISBN 13 : 1118478053
Total Pages : 724 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Biomaterials from Nature for Advanced Devices and Therapies by : Nuno M. Neves

Download or read book Biomaterials from Nature for Advanced Devices and Therapies written by Nuno M. Neves and published by John Wiley & Sons. This book was released on 2016-10-24 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: In-depth information on natural biomaterials and their applications for translational medicine! Undiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world A must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work Link to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used