The Vascular System

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Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman
Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Pathology: A Modern Case Study

Author : Howard Reisner
Publisher : McGraw Hill Professional
ISBN 13 : 0071821236
Total Pages : 622 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Pathology: A Modern Case Study by : Howard Reisner

Download or read book Pathology: A Modern Case Study written by Howard Reisner and published by McGraw Hill Professional. This book was released on 2014-09-22 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.

Regulation of Coronary Blood Flow

Author : Michitoshi Inoue
Publisher : Springer Science & Business Media
ISBN 13 : 4431683674
Total Pages : 330 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Regulation of Coronary Blood Flow by : Michitoshi Inoue

Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Angiogenesis Assays

Author : Carolyn A. Staton
Publisher : John Wiley & Sons
ISBN 13 : 047002934X
Total Pages : 410 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Angiogenesis Assays by : Carolyn A. Staton

Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.

Anatomy and Physiology

Author : J. Gordon Betts
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
ISBN 13 : 1615047239
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Dynamics Of The Vascular System: Interaction With The Heart (Second Edition)

Author : John K-j Li
Publisher : World Scientific
ISBN 13 : 9814723762
Total Pages : 296 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Dynamics Of The Vascular System: Interaction With The Heart (Second Edition) by : John K-j Li

Download or read book Dynamics Of The Vascular System: Interaction With The Heart (Second Edition) written by John K-j Li and published by World Scientific. This book was released on 2018-09-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of the book was written employing mathematical techniques to formulate the physical principles involved in the structural and functional correlates of the underlying physiology.This current and self-contained second edition updates many of the new findings since its first edition a decade ago. It also includes a new chapter on the 'Interaction with the Heart'. The dynamics of the arterial system, the venous system, the microcirculation and their interaction with the heart are quantitatively described in terms of their structures and functions. Clinical measurements, applications to the cardiovascular field and physiological mechanisms are clearly identified throughout the text. Most importantly, worked examples are provided, such that the readers can appreciate the application aspects of the underlying formulation.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Brief History of Blood and Lymphatic Vessels

Author : Andreas Bikfalvi
Publisher : Springer
ISBN 13 : 3319743767
Total Pages : 188 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis A Brief History of Blood and Lymphatic Vessels by : Andreas Bikfalvi

Download or read book A Brief History of Blood and Lymphatic Vessels written by Andreas Bikfalvi and published by Springer. This book was released on 2018-04-13 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it ́s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.

Control of Cardiac Output

Author : David Young
Publisher : Biota Publishing
ISBN 13 : 1615040226
Total Pages : 110 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Control of Cardiac Output by : David Young

Download or read book Control of Cardiac Output written by David Young and published by Biota Publishing. This book was released on 2010-01-01 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the heart itself. The heart’s rate of output cannot exceed the rate of venous return to it, and therefore, the factors governing venous return are primarily responsible for control of output from the heart. Venous return is affected by its pressure gradient and resistance to flow throughout the vascular system. The pressure gradient for venous return is a function of several factors including the blood volume flowing through the system, the unstressed vascular volume of the circulatory system, its capacitance, mean systemic pressure, and right atrial pressure. Resistance to venous return is the sum of total vascular resistance from the aortic valve to the right atrium. The sympathetic nervous system and vasoactive circulating hormones affect short-term resistance, whereas local tissue blood flow autoregulatory mechanisms are the dominant determinants of long-term resistance to venous return. The strength of contraction of the heart responds to changes in atrial pressure driven by changes in venous return, with small changes in atrial pressure eliciting large changes in strength of contraction, as described by the Frank–Starling mechanism. In addition, the autonomic nervous system input to the heart alters myocardial pumping ability in response to cardiovascular challenges. The function of the cardiovascular system is strongly affected by the operation of the renal sodium excretion–body fluid volume–arterial pressure negative feedback system that maintains arterial blood pressure at a controlled value over long periods. The intent of this volume is to integrate the basic knowledge of these cardiovascular system components into an understanding of cardiac output regulation. Table of Contents: Introduction / Venous Return / Cardiac Function / Integrated Analysis of Cardiac Output Control / Analysis of Cardiac Output Regulation by Computer Simulation / Analysis of Cardiac Output Control in Response to Challenges / Conclusion / References / Author Biography

The Primo Vascular System

Author : Kwang-Sup Soh
Publisher : Springer Science & Business Media
ISBN 13 : 1461406013
Total Pages : 327 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis The Primo Vascular System by : Kwang-Sup Soh

Download or read book The Primo Vascular System written by Kwang-Sup Soh and published by Springer Science & Business Media. This book was released on 2011-11-03 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings from the first International Symposium on Primo Vascular System 2010 (ISPS 2010) with special topics on cancer and regeneration was held in Jecheon, Korea during September 17-18, 2010. Includes coverage of new study results that have better revealed the functional aspects of PVS, including its roles in the areas of regenerative medicine and cancer.

Vascular Biology of the Placenta

Author : Yuping Wang
Publisher : Biota Publishing
ISBN 13 : 1615047514
Total Pages : 126 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Vascular Biology of the Placenta by : Yuping Wang

Download or read book Vascular Biology of the Placenta written by Yuping Wang and published by Biota Publishing. This book was released on 2017-06-23 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

The Endothelium

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

The ESC Textbook of Vascular Biology

Author : Rob Krams
Publisher : Oxford University Press
ISBN 13 : 0198755775
Total Pages : 347 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The ESC Textbook of Vascular Biology by : Rob Krams

Download or read book The ESC Textbook of Vascular Biology written by Rob Krams and published by Oxford University Press. This book was released on 2017 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research.

Compendium of Histology

Author : Anders Rehfeld
Publisher : Springer
ISBN 13 : 3319418734
Total Pages : 670 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Compendium of Histology by : Anders Rehfeld

Download or read book Compendium of Histology written by Anders Rehfeld and published by Springer. This book was released on 2017-09-07 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been designed to help medical students succeed with their histology classes, while using less time on studying the curriculum. The book can both be used on its own or as a supplement to the classical full-curriculum textbooks normally used by the students for their histology classes. Covering the same curriculum as the classical textbooks, from basic tissue histology to the histology of specific organs, this book is formatted and organized in a much simpler and intuitive way. Almost all text is formatted in bullets or put into structured tables. This makes it quick and easy to digest, helping the student get a good overview of the curriculum. It is easy to locate specific information in the text, such as the size of cellular structures etc. Additionally, each chapter includes simplified illustrations of various histological features. The aim of the book is to be used to quickly brush up on the curriculum, e.g. before a class or an exam. Additionally, the book includes guides to distinguish between the different histological tissues and organs that can be presented to students microscopically, e.g. during a histology spot test. This guide lists the specific characteristics of the different histological specimens and also describes how to distinguish a specimen from other similar specimens. For each histological specimen, a simplified drawing and a photomicrograph of the specimen, is presented to help the student recognize the important characteristics in the microscope. Lastly, the book contains multiple “memo boxes” in which parts of the curriculum are presented as easy-to-remember mnemonics.

Vascular Access

Author : Samuel E. Wilson
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1605472034
Total Pages : 328 pages
Book Rating : 4.6/5 (54 download)

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Book Synopsis Vascular Access by : Samuel E. Wilson

Download or read book Vascular Access written by Samuel E. Wilson and published by Lippincott Williams & Wilkins. This book was released on 2010 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical and comprehensive book provides "how-to" information on all aspects of access to the vascular system for hemodialysis, parenteral nutrition, chemotherapy, and resuscitation. Preoperative evaluation, operations, noninvasive procedures, complications, and other aspects are detailed. This edition provides increased coverage of non-interventional techniques and includes new chapters on management of thrombophilia in hemodialysis patients; modulation of the immune system to prevent myointimal hyperplasia; synthetic grafts; venous outflow stenting for salvage of vascular access procedures; and ultrasound in vascular access procedures. This book is essential for all clinicians treating patients who require vascular access, including vascular surgeons, general surgeons, nephrologists, dialysis technicians and nurses, radiologists, and cardiologists.

Fundamentals of Vascular Biology

Author : Margarethe Geiger
Publisher : Springer
ISBN 13 : 3030122700
Total Pages : 400 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Fundamentals of Vascular Biology by : Margarethe Geiger

Download or read book Fundamentals of Vascular Biology written by Margarethe Geiger and published by Springer. This book was released on 2019-05-08 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-structured textbook offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms and development of the different parts of the vascular system (including the heart), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, in animal models, and ex vivo. This book is based on a PhD Course for students from various bioscientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master ́s Students in vascular biology and biomedicine in general and a helpful tool for young researchers world-wide wishing to gain or refresh their knowledge in this field.