The Usage Of Genomic Selection Strategy In Plant Breeding

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Genomic Selection in Plants

Author : Ani A. Elias
Publisher : CRC Press
ISBN 13 : 1000655997
Total Pages : 265 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Genomic Selection in Plants by : Ani A. Elias

Download or read book Genomic Selection in Plants written by Ani A. Elias and published by CRC Press. This book was released on 2022-08-18 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic selection (GS) is a promising tool in the field of breeding especially in the era where genomic data is becoming cheaper. The potential of this tool has not been realized due to its limited adaptation in various crops. Marker Assisted Selection (MAS) has been the method of choice for plant breeders while using the genomic information in the breeding pipeline. MAS, however, fails to capture vital minor gene effects while focusing only on the major genes, which is not ideal for breeding advancement especially for quantitative traits such as yield. The main aim of statistical methodologies coming under the umbrella of GS on using the whole genome information is to predict potential candidates for breeding advancement while optimizing the use of resources such as land, manpower, and most importantly time. Lack of proper understanding of the methods and their applications is one of the reasons why breeders shy away from this tool. The book is meant for biologists, especially breeders, and provides a comprehensive idea of the statistical methodologies used in GS, guidance on the choice of models, and design of datasets. The book also encourages the readers to adopt GS by demonstrating the current scenarios of these models in some of the important crops among oilseeds, vegetables, legumes, tuber crops, and cereals. For ease of implementation of GS, the book also provides hands-on scripts on GS data design and modeling in a popular open-source statistical program. Additionally, prospective in GS model development and thereby enhancement in crop improvement programs is discussed.

Genomic Selection for Crop Improvement

Author : Rajeev K. Varshney
Publisher : Springer
ISBN 13 : 3319631705
Total Pages : 265 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Genomic Selection for Crop Improvement by : Rajeev K. Varshney

Download or read book Genomic Selection for Crop Improvement written by Rajeev K. Varshney and published by Springer. This book was released on 2017-12-05 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Selection for Crop Improvement serves as handbook for users by providing basic as well as advanced understandings of genomic selection. This useful review explains germplasm use, phenotyping evaluation, marker genotyping methods, and statistical models involved in genomic selection. It also includes examples of ongoing activities of genomic selection for crop improvement and efforts initiated to deploy the genomic selection in some important crops. In order to understand the potential of GS breeding, it is high time to bring complete information in the form of a book that can serve as a ready reference for geneticist and plant breeders.

Handbook of Near-Infrared Analysis

Author : Emil W. Ciurczak
Publisher : CRC Press
ISBN 13 : 1351269860
Total Pages : 1308 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Handbook of Near-Infrared Analysis by : Emil W. Ciurczak

Download or read book Handbook of Near-Infrared Analysis written by Emil W. Ciurczak and published by CRC Press. This book was released on 2021-05-20 with total page 1308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid, inexpensive, and easy-to-deploy, near-infrared (NIR) spectroscopy can be used to analyze samples of virtually any composition, origin, and condition. The Handbook of Near Infrared Analysis, Fourth Edition, explores the factors necessary to perform accurate and time- and cost-effective analyses across a growing spectrum of disciplines. This updated and expanded edition incorporates the latest advances in instrumentation, computerization, chemometrics applied to NIR spectroscopy, and method development in NIR spectroscopy, and underscores current trends in sample preparation, calibration transfer, process control, data analysis, instrument performance testing, and commercial NIR instrumentation. This work offers readers an unparalleled combination of theoretical foundations, cutting-edge applications, and practical experience. Additional features include the following: Explains how to perform accurate as well as time- and cost-effective analyses. Reviews software-enabled chemometric methods and other trends in data analysis. Highlights novel applications in pharmaceuticals, polymers, plastics, petrochemicals, textiles, foods and beverages, baked products, agricultural products, biomedicine, nutraceuticals, and counterfeit detection. Underscores current trends in sample preparation, calibration transfer, process control, data analysis, and multiple aspects of commercial NIR instrumentation. Offering the most complete single-source guide of its kind, the Handbook of Near Infrared Analysis, Fourth Edition, continues to offer practicing chemists and spectroscopists an unparalleled combination of theoretical foundations, cutting-edge applications, and detailed practical experience provided firsthand by more than 50 experts in the field.

The Usage of Genomic Selection Strategy in Plant Breeding

Author : Mohd Shamshad
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)

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Book Synopsis The Usage of Genomic Selection Strategy in Plant Breeding by : Mohd Shamshad

Download or read book The Usage of Genomic Selection Strategy in Plant Breeding written by Mohd Shamshad and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Major paradigm shift in plant breeding since the availability of molecular marker technology is that mapping and characterizing the genetic loci that control a trait will lead to improved breeding. Often, one of the rationales for cloning of QTL is to develop the "perfect marker" for MAS, perhaps based on a functional polymorphism. In contrast, an advantage of genomic selection is precisely its black box approach to exploiting genotyping technology to expedite genetic progress. This is an advantage in our view because it does not rely on a "breeding by design" engineering approach to cultivar development requiring knowledge of biological function before the creation of phenotypes. Breeders can therefore use genomic selection without the large upfront cost of obtaining that knowledge. In addition, genomic selection can maintain the creative nature of phenotypic selection which couple's random mutation and recombination to sometimes arrive at solutions outside the engineer's scope. Currently, the lion's share of research on genomic selection has been performed in livestock breeding, where effective population size, extent of LD, breeding objectives, experimental design, and other characteristics of populations and breeding programs are quite different from those of crop species. Nevertheless, a great number of findings within this literature are very illuminating for genomic selection in crops and should be studied and built upon by crop geneticists and breeders. The application of powerful, relatively new statistical methods to the problem of high dimensional marker data for genomic selection has been nearly as important to the development of genomic selection as the creation of high-density marker platforms and greater computing power. The methods can be classified by what type of genetic architecture they try to capture.

Quantitative Genetics and Selection in Plant Breeding

Author : Günter Wricke
Publisher : Walter de Gruyter
ISBN 13 : 3110837528
Total Pages : 421 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Quantitative Genetics and Selection in Plant Breeding by : Günter Wricke

Download or read book Quantitative Genetics and Selection in Plant Breeding written by Günter Wricke and published by Walter de Gruyter. This book was released on 2010-10-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Genetics and Selection in Plant Breeding.

Plant Breeding: Past, Present and Future

Author : John E. Bradshaw
Publisher : Springer
ISBN 13 : 3319232851
Total Pages : 710 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Plant Breeding: Past, Present and Future by : John E. Bradshaw

Download or read book Plant Breeding: Past, Present and Future written by John E. Bradshaw and published by Springer. This book was released on 2016-03-08 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to help plant breeders by reviewing past achievements, currently successful practices, and emerging methods and techniques. Theoretical considerations are also presented to strike the right balance between being as simple as possible but as complex as necessary. The United Nations predicts that the global human population will continue rising to 9.0 billion by 2050. World food production will need to increase between 70-100 per cent in just 40 years. First generation bio-fuels are also using crops and cropland to produce energy rather than food. In addition, land area used for agriculture may remain static or even decrease as a result of degradation and climate change, despite more land being theoretically available, unless crops can be bred which tolerate associated abiotic stresses. Lastly, it is unlikely that steps can be taken to mitigate all of the climate change predicted to occur by 2050, and beyond, and hence adaptation of farming systems and crop production will be required to reduce predicted negative effects on yields that will occur without crop adaptation. Substantial progress will therefore be required in bridging the yield gap between what is currently achieved per unit of land and what should be possible in future, with the best farming methods and best storage and transportation of food, given the availability of suitably adapted cultivars, including adaptation to climate change. My book is divided into four parts: Part I is an historical introduction; Part II deals with the origin of genetic variation by mutation and recombination of DNA; Part III explains how the mating system of a crop species determines the genetic structure of its landraces; Part IV considers the three complementary options for future progress: use of sexual reproduction in further conventional breeding, base broadening and introgression; mutation breeding; and genetically modified crops.

Plant Breeding Reviews, Volume 45

Author : Irwin Goldman
Publisher : John Wiley & Sons
ISBN 13 : 1119828228
Total Pages : 477 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Plant Breeding Reviews, Volume 45 by : Irwin Goldman

Download or read book Plant Breeding Reviews, Volume 45 written by Irwin Goldman and published by John Wiley & Sons. This book was released on 2021-10-21 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Breeding Reviews presents state-of-the-art reviews on plant genetics and the breeding of all types of crops by both traditional means and molecular methods. Many of the crops widely grown today stem from a very narrow genetic base; understanding and preserving crop genetic resources is vital to the security of food systems worldwide. The emphasis of the series is on methodology, a fundamental understanding of crop genetics, and applications to major crops.

The Maize Genome

Author : Jeffrey Bennetzen
Publisher : Springer
ISBN 13 : 3319974270
Total Pages : 390 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis The Maize Genome by : Jeffrey Bennetzen

Download or read book The Maize Genome written by Jeffrey Bennetzen and published by Springer. This book was released on 2018-11-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world’s human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.

Molecular Plant Breeding

Author : Yunbi Xu
Publisher : CABI
ISBN 13 : 1845936248
Total Pages : 756 pages
Book Rating : 4.8/5 (459 download)

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Book Synopsis Molecular Plant Breeding by : Yunbi Xu

Download or read book Molecular Plant Breeding written by Yunbi Xu and published by CABI. This book was released on 2010 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in plant genomics and molecular biology have revolutionized our understanding of plant genetics, providing new opportunities for more efficient and controllable plant breeding. Successful techniques require a solid understanding of the underlying molecular biology as well as experience in applied plant breeding. Bridging the gap between developments in biotechnology and its applications in plant improvement, Molecular Plant Breeding provides an integrative overview of issues from basic theories to their applications to crop improvement including molecular marker technology, gene mapping, genetic transformation, quantitative genetics, and breeding methodology.

Genetic Data Analysis for Plant and Animal Breeding

Author : Fikret Isik
Publisher : Springer
ISBN 13 : 3319551779
Total Pages : 409 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Genetic Data Analysis for Plant and Animal Breeding by : Fikret Isik

Download or read book Genetic Data Analysis for Plant and Animal Breeding written by Fikret Isik and published by Springer. This book was released on 2017-09-09 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the gap between textbooks of quantitative genetic theory, and software manuals that provide details on analytical methods but little context or perspective on which methods may be most appropriate for a particular application. Accordingly this book is composed of two sections. The first section (Chapters 1 to 8) covers topics of classical phenotypic data analysis for prediction of breeding values in animal and plant breeding programs. In the second section (Chapters 9 to 13) we provide the concept and overall review of available tools for using DNA markers for predictions of genetic merits in breeding populations. With advances in DNA sequencing technologies, genomic data, especially single nucleotide polymorphism (SNP) markers, have become available for animal and plant breeding programs in recent years. Analysis of DNA markers for prediction of genetic merit is a relatively new and active research area. The algorithms and software to implement these algorithms are changing rapidly. This section represents state-of-the-art knowledge on the tools and technologies available for genetic analysis of plants and animals. However, readers should be aware that the methods or statistical packages covered here may not be available or they might be out of date in a few years. Ultimately the book is intended for professional breeders interested in utilizing these tools and approaches in their breeding programs. Lastly, we anticipate the usage of this volume for advanced level graduate courses in agricultural and breeding courses.

Multivariate Statistical Machine Learning Methods for Genomic Prediction

Author : Osval Antonio Montesinos López
Publisher : Springer Nature
ISBN 13 : 3030890104
Total Pages : 707 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Multivariate Statistical Machine Learning Methods for Genomic Prediction by : Osval Antonio Montesinos López

Download or read book Multivariate Statistical Machine Learning Methods for Genomic Prediction written by Osval Antonio Montesinos López and published by Springer Nature. This book was released on 2022-02-14 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

Genomic Selection: Lessons Learned and Perspectives

Author : Johannes W. R. Martini
Publisher : Frontiers Media SA
ISBN 13 : 2889746747
Total Pages : 261 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Genomic Selection: Lessons Learned and Perspectives by : Johannes W. R. Martini

Download or read book Genomic Selection: Lessons Learned and Perspectives written by Johannes W. R. Martini and published by Frontiers Media SA. This book was released on 2022-09-15 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic selection (GS) has been the most prominent topic in breeding science in the last two decades. The continued interest is promoted by its huge potential impact on the efficiency of breeding. Predicting a breeding value based on molecular markers and phenotypic values of relatives may be used to manipulate three parameters of the breeder's equation. First, the accuracy of the selection may be improved by predicting the genetic value more reliably when considering the records of relatives and the realized genomic relationship. Secondly, genotyping and predicting may be more cost effective than comprehensive phenotyping. Resources can instead be allocated to increasing population sizes and selection intensity. The third, probably most important factor, is time. As shown in dairy cattle breeding, reducing cycle time by crossing selection candidates earlier may have the strongest impact on selection gain. Many different prediction models have been used, and different ways of using predicted values in a breeding program have been explored. We would like to address the questions: i. How did GS change breeding schemes of different crops in the last 20 years? ii. What was the impact on realized selection gain? iii. What would be the best structure of a crop-specific breeding scheme to exploit the full potential of GS? iv. What is the potential of hybrid prediction, epistasis effect models, deep learning methods and other extensions of the standard prediction of additive effects? v. What are the long-term effects of GS? vi. Can predictive breeding approaches also be used to harness genetic resources from germplasm banks in a more efficient way to adapt current germplasm to new environmental challenges? This Research Topic welcomes submissions of Original Research papers, Opinions, Perspectives, Reviews, and Mini-Reviews related to these themes: 1. Genomic selection: statistical methodology 2. The (optimal) use of GS in breeding schemes 3. Practical experiences with GS (selection gain, long-term effects, negative side effects) 4. Predictive approaches to harness genetic resources Concerning point 1): If an original research paper compares different methods empirically without theoretical considerations on when one or the other method should be better, the methods should be compared with at least five different data sets. The data sets should differ either in crop, genotyping method or its source, for instance from a breeding program or gene bank accessions. Concerning point 2): Manuscripts addressing the use of GS in breeding schemes should illustrate breeding schemes that are run in practice. General ideas about schemes that may be run in the future may be considered as 'Perspective' articles. Conflict of Interest statements: - Topic Editor Valentin Wimmer is affiliated to KWS SAAT SE & Co. KGaA, Germany. - Topic Editor Brian Gardunia is affiliated to Bayer Crop Sciences and has a collaboration with AbacusBio, and is an author on patents with Bayer Crop Sciences. The other Topic Editors did not disclose any conflicts of interest. Image credit: CIMMYT, reproduced under the CC BY-NC-SA 2.0 license

Integrating Genomic Selection and Genome Editing Strategies to Accelerate Potato Breeding

Author : Felix Eugenio Enciso Rodriguez
Publisher :
ISBN 13 : 9781392078624
Total Pages : 167 pages
Book Rating : 4.0/5 (786 download)

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Book Synopsis Integrating Genomic Selection and Genome Editing Strategies to Accelerate Potato Breeding by : Felix Eugenio Enciso Rodriguez

Download or read book Integrating Genomic Selection and Genome Editing Strategies to Accelerate Potato Breeding written by Felix Eugenio Enciso Rodriguez and published by . This book was released on 2019 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a staple food, the potato (Solanum tuberosum L.) plays an important role in human nutrition and it is currently the third most important food crop after rice and wheat. However, the potato crop faces high production losses caused mainly by biotic factors. With the advent of cutting-edge technologies suitable for potatoes, there is an increasing possibility to accelerate genetic progress and variety generation. To contribute to the implementation of genomic strategies to accelerate potato breeding, three different approaches were used. First, whole genome regressions were conducted using additive and dominant allele dosage models for late blight and common scab resistance in tetraploid potatoes. Multiple Single Nucleotide Polymorphisms (SNPs), contribute to late blight resistance, uncovering the introgression history for this trait whereas an unreported locus with a sizable contribution to common scab resistance was detected. Prediction accuracy assessments demonstrated that 90% of the genetic variance could be captured with an additive model, demonstrating the applicability of genomic prediction for tetraploid potato breeding. Second, a genome editing approach was implemented to breakdown the S-RNase -based self incompatibly in diploid potatoes. New S-RNase allelic variants, with flower-restricted expression, were identified in two self-incompatible (SI) diploid potatoes and mapped to chromosome I in a low recombination region. A dual single-guide RNA strategy was used to generate S-RNase knock-out lines producing premature stop codons on each targeted S-RNase allele. Self-compatibility was achieved in T0 knock-outs and stable transmitted to T1 lines. Additionally, Cas-9 free plants were also obtained. Plasticity in the self-compatible response was also observed in wild-type lines, presumably associated with non-stylar and environmental factors. Third, validation of the IPI-O4 -mediated suppression of the RB-based late blight resistance was conducted using in vivo and in vitro approaches. The hypersensitive response (HR) was confirmed when IPI-O1 was co-infiltrated with the RB gene from Solanum bulbocastanum using a heterologous system. However, HR was observed when IPI-O1 and IPI-O4 were infiltrated in transgenic potato lines carrying a synthetic RB gene containing a Coiled-Coil (CC) domain from S. pinnatisectum. Further work should be conducted to confirm this un-reported interaction. Similarly, we could not validate CC-dimerization using yeast-two hybrid assays and therefore more extensive experiments should be conducted to confirm this result. Ultimately, these genomic approaches open a new window to accelerate the generation of new potato varieties. Genomic selection strategies along with targeted mutagenesis will expand the boundaries of both approaches, reducing the potato breeding cycle considerably while maintaining genetic diversity, and providing access to genomic regions with low or null recombination in potatoes.

Advances in Wheat Genetics: From Genome to Field

Author : Yasunari Ogihara
Publisher : Springer
ISBN 13 : 4431556753
Total Pages : 421 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Advances in Wheat Genetics: From Genome to Field by : Yasunari Ogihara

Download or read book Advances in Wheat Genetics: From Genome to Field written by Yasunari Ogihara and published by Springer. This book was released on 2015-09-15 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings is a collection of 46 selected papers that were presented at the 12th International Wheat Genetics Symposium (IWGS). Since the launch of the wheat genome sequencing project in 2005, the arrival of draft genome sequences has marked a new era in wheat genetics and genomics, catalyzing rapid advancement in the field. This book provides a comprehensive review of the forefront of wheat research, across various important topics such as germplasm and genetic diversity, cytogenetics and allopolyploid evolution, genome sequencing, structural and functional genomics, gene function and molecular biology, biotic stress, abiotic stress, grain quality, and classical and molecular breeding. Following an introduction, 9 parts of the book are dedicated to each of these topics. A final, 11th part entitled “Toward Sustainable Wheat Production” contains 7 excellent papers that were presented in the 12th IWGS Special Session supported by the OECD. With rapid population growth and radical climate changes, the world faces a global food crisis and is in need of another Green Revolution to boost yields of wheat and other widely grown staple crops. Although this book focuses on wheat, many of the newly developed techniques and results presented here can be applied to other plant species with large and complex genomes. As such, this volume is highly recommended for all students and researchers in wheat sciences and related plant sciences and for those who are interested in stable food production and food security.

The Alfalfa Genome

Author : Long-Xi Yu
Publisher : Springer Nature
ISBN 13 : 3030744663
Total Pages : 296 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis The Alfalfa Genome by : Long-Xi Yu

Download or read book The Alfalfa Genome written by Long-Xi Yu and published by Springer Nature. This book was released on 2021-07-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.

Rice Genomics, Genetics and Breeding

Author : Takuji Sasaki
Publisher : Springer
ISBN 13 : 9811074615
Total Pages : 556 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Rice Genomics, Genetics and Breeding by : Takuji Sasaki

Download or read book Rice Genomics, Genetics and Breeding written by Takuji Sasaki and published by Springer. This book was released on 2018-02-14 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest advances in rice genomics, genetics and breeding, with a special focus on their importance for rice biology and how they are breathing new life into traditional genetics. Rice is the main staple food for more than half of the world’s population. Accordingly, sustainable rice production is a crucial issue, particularly in Asia and Africa, where the population continues to grow at an alarming rate. The book’s respective chapters offer new and timely perspectives on the synergistic effects of genomics and genetics in novel rice breeding approaches, which can help address the urgent issue of providing enough food for a global population that is expected to reach 9 billion by 2050.

Handbook of Statistical Genomics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 1119429250
Total Pages : 1828 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.