The Toxicology Of Essential And Nonessential Metals

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Fish Physiology: Homeostasis and Toxicology of Essential Metals

Author :
Publisher : Academic Press
ISBN 13 : 9780123786364
Total Pages : 520 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Fish Physiology: Homeostasis and Toxicology of Essential Metals by :

Download or read book Fish Physiology: Homeostasis and Toxicology of Essential Metals written by and published by Academic Press. This book was released on 2011-08-11 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses. The companion volume, Homeostasis and Toxicology of Non-Essential Metals, Volume 31B, covers metals that have no known nutritive function in fish at present, but which are toxic at fairly low levels, such as Ag, Al, Cd, Pb, Hg, As, Sr, and U. In addition, three chapters in Volumes 31A and 31B on Basic Principles (Chapter 1, 31A), Field Studies and Ecological Integration (Chapter 9, 31A) and Modeling the Physiology and Toxicology of Metals (Chapter 9, 31B) act as integrative summaries and make these two volumes a vital set for readers. All major essential metals of interest are covered in metal-specific chapters Each metal-specific chapter is written by fish physiologists/toxicologists who are recognized authorities for that metal A common format is featured throughout this two volume edition

Essential and Non-essential Metals

Author : Anuradha Mudipalli
Publisher : Springer
ISBN 13 : 3319554484
Total Pages : 235 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Essential and Non-essential Metals by : Anuradha Mudipalli

Download or read book Essential and Non-essential Metals written by Anuradha Mudipalli and published by Springer. This book was released on 2017-07-14 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of action for different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do.

The Toxicology of Essential and Nonessential Metals

Author : Nichole Coleman, PhD
Publisher : Lulu.com
ISBN 13 : 1483469085
Total Pages : 198 pages
Book Rating : 4.4/5 (834 download)

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Book Synopsis The Toxicology of Essential and Nonessential Metals by : Nichole Coleman, PhD

Download or read book The Toxicology of Essential and Nonessential Metals written by Nichole Coleman, PhD and published by Lulu.com. This book was released on 2017-05-11 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: No matter how careful we are at using metals in industrial processes, some level of human exposure is unavoidable. Countless metals are obtained through mining and smelting activities that amplify their distribution throughout the environment. Applications of metals in industry, medicine, and agriculture have increased our exposure. These metals are not merely an occupational hazard for those working with them-they affect consumers and anyone exposed through environmental contamination. Even worse, they cannot be destroyed and are thus non-biodegradable. The blades we use, the pots and pans we cook with, children's face paint, and facial makeup contain toxic metals. Toxic heavy metals are also found in cigarettes, gourmet foods such as seasonings, fish, and chocolates. When you sprinkle a dish with Himalayan sea salt, you may end up ingesting toxic metals such as arsenic, cadmium and lead.

Metal Chelation in Medicine

Author : Robert R Crichton
Publisher : Royal Society of Chemistry
ISBN 13 : 1782623892
Total Pages : 336 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Metal Chelation in Medicine by : Robert R Crichton

Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Handbook on the Toxicology of Metals: Volume II: Specific Metals

Author : Gunnar F. Nordberg
Publisher : Academic Press
ISBN 13 : 0128231386
Total Pages : 1054 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Handbook on the Toxicology of Metals: Volume II: Specific Metals by : Gunnar F. Nordberg

Download or read book Handbook on the Toxicology of Metals: Volume II: Specific Metals written by Gunnar F. Nordberg and published by Academic Press. This book was released on 2021-12-01 with total page 1054 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides complete coverage of 38 individual metals and their compounds. This volume is the second volume of a two-volume work which emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. - Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems with a focus on human health effects - Includes information on sources, transport, and the transformation of metals in the environment - Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment, and prevention of 38 metallic elements and their compounds

Chelation Therapy in the Treatment of Metal Intoxication

Author : Jan Aaseth
Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chelation Therapy in the Treatment of Metal Intoxication by : Jan Aaseth

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic

Author : Peggy L. Carver
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110526980
Total Pages : 640 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic by : Peggy L. Carver

Download or read book Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic written by Peggy L. Carver and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-01-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 19, entitled Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic of the series Metal Ions in Life Sciences centers on the role of metal ions in clinical medicine. Metal ions are tightly regulated in human health: while essential to life, they can be toxic as well. Following an introductory chapter briefly discussing several important metal-related drugs and diseases and a chapter about drug development, the focus is fi rst on iron: its essentiality for pathogens and humans as well as its toxicity. Chelation therapy is addressed in the context of thalassemia, its relationship to neurodegenerative diseases and also the risks connected with iron administration are pointed out. A subject of intense debate is the essentiality of chromium and vanadium. For example, chromium(III) compounds are taken as a nutritional supplement by athletes and bodybuilders; in contrast, chromate, Cr(VI), is toxic and a carcinogen for humans. The benefi cial and toxic effects of manganese, cobalt, and copper on humans are discussed. The need for antiparasitic agents is emphasized as well as the clinical aspects of metal-containing antidotes for cyanide poisoning. In addition to the essential and possibly essential ones, also other metal ions play important roles in human health, causing harm (like the metalloid arsenic, lead or cadmium) or being used in diagnosis or treatment of human diseases, like gadolinium, gallium, lithium, gold, silver or platinum. The impact of this vibrant research area on metals in the clinic is provided in 14 stimulating chapters, written by internationally recognized experts from the Americas, Europe and China, and is manifested by approximately 2000 references, and about 90 illustrations and tables. Essential Metals in Medicine: Therapeutic Use and Toxicity of Metal Ions in the Clinic is an essential resource for scientists working in the wide range from pharmacology, enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine ... not forgetting that it also provides excellent information for teaching.

Handbook of Human Toxicology

Author : Edward J. Massaro
Publisher : CRC Press
ISBN 13 : 9781439805756
Total Pages : 1198 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Handbook of Human Toxicology by : Edward J. Massaro

Download or read book Handbook of Human Toxicology written by Edward J. Massaro and published by CRC Press. This book was released on 1997-07-09 with total page 1198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human to

Diet and Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Binding, Transport and Storage of Metal Ions in Biological Cells

Author : Wolfgang Maret
Publisher : Royal Society of Chemistry
ISBN 13 : 1782622829
Total Pages : 990 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Binding, Transport and Storage of Metal Ions in Biological Cells by : Wolfgang Maret

Download or read book Binding, Transport and Storage of Metal Ions in Biological Cells written by Wolfgang Maret and published by Royal Society of Chemistry. This book was released on 2014-07-09 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

Ecotoxicology of Metals in Invertebrates

Author : Reinhard Dallinger
Publisher : CRC Press
ISBN 13 : 9780873717342
Total Pages : 486 pages
Book Rating : 4.7/5 (173 download)

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Book Synopsis Ecotoxicology of Metals in Invertebrates by : Reinhard Dallinger

Download or read book Ecotoxicology of Metals in Invertebrates written by Reinhard Dallinger and published by CRC Press. This book was released on 1993-01-25 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecotoxicology of Metals in Invertebrates reviews the state of the art in research concerning metal exposure of marine, freshwater, and terrestrial invertebrates. The book focuses on the uptake and accumulation of essential and non-essential trace metals by invertebrates, metal detoxification and involved mechanisms, adaptations to metal stress, metal regulation and elimination, distribution and speciation of metals in different organs and tissues, and interaction of metals with biotic and abiotic factors. Toxicological studies involve histopathological, electron microscopic, physiological, and biochemical methods. The book emphasizes the ecological and ecotoxicological implications that can be derived from metal exposure of invertebrates in the field. The significance of background concentrations, the evaluation of critical concentrations, and the establishment of environmental quality criteria are discussed as well. Ecotoxicology of Metals in Invertebrates is an excellent reference for ecologists, ecotoxicologists, environmental scientists, ecophysiologists, and students.

The Biological Chemistry of Nickel

Author : Deborah Zamble
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010582
Total Pages : 396 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis The Biological Chemistry of Nickel by : Deborah Zamble

Download or read book The Biological Chemistry of Nickel written by Deborah Zamble and published by Royal Society of Chemistry. This book was released on 2017-03-24 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

Herbs, Spices and Medicinal Plants

Author : Mohammad B. Hossain
Publisher : John Wiley & Sons
ISBN 13 : 1119036615
Total Pages : 400 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Herbs, Spices and Medicinal Plants by : Mohammad B. Hossain

Download or read book Herbs, Spices and Medicinal Plants written by Mohammad B. Hossain and published by John Wiley & Sons. This book was released on 2020-10-05 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest research on the health benefits and optimal processing technologies of herbs and spices This book provides a comprehensive overview of the health benefits, analytical techniques used, and effects of processing upon the physicochemical properties of herbs and spices. Presented in three parts, it opens with a section on the technological and health benefits of herbs and spices. The second part reviews the effect of classical and novel processing techniques on the properties of herbs/spices. The third section examines extraction techniques and analytical methodologies used for herbs and spices. Filled with contributions from experts in academia and industry, Herbs, Spices and Medicinal Plants: Processing, Health Benefits and Safety offers chapters covering thermal and non-thermal processing of herbs and spices, recent developments in high-quality drying of herbs and spices, conventional and novel techniques for extracting bioactive compounds from herbs and spices, and approaches to analytical techniques. It also examines purification and isolation techniques for enriching bioactive phytochemicals, medicinal properties of herbs and spices, synergy in whole-plant medicine, potential applications of polyphenols from herbs and spices in dairy products, biotic and abiotic safety concerns, and adverse human health effects and regulation of metal contaminants in terrestrial plant-derived food and phytopharmaceuticals. Covers the emerging health benefits of herbs and spices, including their use as anti-diabetics, anti-inflammatories, and anti-oxidants Reviews the effect of classical and novel processing techniques on the properties of herbs and spices Features informed perspectives from noted academics and professionals in the industry Part of Wiley's new IFST Advances in Food Science series Herbs, Spices and Medicinal Plants is an important book for companies, research institutions, and universities active in the areas of food processing and the agri-food environment. It will appeal to food scientists and engineers, environmentalists, and food regulatory agencies.

Toxicology of Marine Mammals

Author : Joseph G. Vos
Publisher : CRC Press
ISBN 13 : 0203165578
Total Pages : 656 pages
Book Rating : 4.2/5 (31 download)

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Book Synopsis Toxicology of Marine Mammals by : Joseph G. Vos

Download or read book Toxicology of Marine Mammals written by Joseph G. Vos and published by CRC Press. This book was released on 2002-12-05 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The activities of modern society have unleashed a range of toxic chemicals into the global environment. Many of these toxicants are now being detected in increasing quantities in the tissues of marine mammals, most notably in top predators who acquire relatively large amounts of toxic chemicals by ingesting contaminated prey. Toxicology of M

A Textbook of Modern Toxicology

Author : Ernest Hodgson
Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 518 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Textbook of Modern Toxicology by : Ernest Hodgson

Download or read book A Textbook of Modern Toxicology written by Ernest Hodgson and published by McGraw-Hill Medical Publishing. This book was released on 1997 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

Handbook on the Toxicology of Metals

Author : Monica Nordberg
Publisher : Elsevier
ISBN 13 : 0080546102
Total Pages : 1024 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook on the Toxicology of Metals by : Monica Nordberg

Download or read book Handbook on the Toxicology of Metals written by Monica Nordberg and published by Elsevier. This book was released on 2011-04-28 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds. * Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more

Handbook on the Toxicology of Metals: Specific metals

Author : Lars Friberg
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 758 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook on the Toxicology of Metals: Specific metals by : Lars Friberg

Download or read book Handbook on the Toxicology of Metals: Specific metals written by Lars Friberg and published by Elsevier Science & Technology. This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.