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Author : Emilia Mayo
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (783 download)
Download or read book The Physiological Relevance of Endogenous Mono-ADP-ribosylation in Signal Transduction written by Emilia Mayo and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alexander Bürkle
Publisher : Springer Science & Business Media
ISBN 13 : 0387360050
Total Pages : 260 pages
Book Rating : 4.3/5 (873 download)
Download or read book Poly(ADP-Ribosyl)ation written by Alexander Bürkle and published by Springer Science & Business Media. This book was released on 2008-01-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenance of genomic stability, transcriptional regulation, cell death and a variety of other cellular phenomena as well as with a variety of pathophysiological conditions, including ischemia-reperfusion damage, Parkinson’s disease, Type I diabetes mellitus, hemorrhagic and septic shock and other inflammatory conditions. Richly illustrated, it offers 19 chapters written by international experts.
Author : Edward A. Dennis
Publisher : Academic Press
ISBN 13 : 0123838622
Total Pages : 604 pages
Book Rating : 4.1/5 (238 download)
Download or read book Transduction Mechanisms in Cellular Signaling written by Edward A. Dennis and published by Academic Press. This book was released on 2011-04-12 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
Author : Bastien D. Gomperts
Publisher : Academic Press
ISBN 13 : 0080919057
Total Pages : 839 pages
Book Rating : 4.0/5 (89 download)
Download or read book Signal Transduction written by Bastien D. Gomperts and published by Academic Press. This book was released on 2009-09-22 with total page 839 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction, 2e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium Extensive conceptual color artwork to assist with comprehension of key topics Instrumental margin notes highlight milestones in signaling mechanisms
Author : Johannes Lukas Bos
Publisher : IOS Press
ISBN 13 : 9781586030162
Total Pages : 298 pages
Book Rating : 4.0/5 (31 download)
Download or read book Molecular Mechanisms of Signal Transduction written by Johannes Lukas Bos and published by IOS Press. This book was released on 2000 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains overviews of topics that have been discussed. It includes contributions from leading experts in the field on small GTPases, protein kinesis, receptors and transcription factors. A particular focus was the influence of oxygen radicals on signalling processes. It also contains the contributions of scientists early in their career, who have made an excellent contribution to the institute.
Author : N. Patrick Higgins
Publisher : Amer Society for Microbiology
ISBN 13 : 9781555812324
Total Pages : 559 pages
Book Rating : 4.8/5 (123 download)
Download or read book The Bacterial Chromosome written by N. Patrick Higgins and published by Amer Society for Microbiology. This book was released on 2005 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the mechanisms governing genetic inheritance. - Provides a link between classical experiments in chromosome physiology and new developments in genetic research. - Covers the fundamental systems required for all bacterial cells to replicate chromosomes and organize genetic information. - Presents complex biochemical reactions, including DNA replication, genetic recombination, and RNA transcription, from both genetic and physical perspectives. - Incorporates the implications of the DNA sequence database with information on horizontal gene transfer and the impact of phage genes on bacterial genomes.
Author : Myron K. Jacobson
Publisher : Springer Science & Business Media
ISBN 13 : 1461585074
Total Pages : 543 pages
Book Rating : 4.4/5 (615 download)
Download or read book ADP-Ribose Transfer Reactions written by Myron K. Jacobson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current interest in NAD (Nicotinamide adenine dinucleotide) in biological systems focuses on its role in ADP-ribose transfer reactions. These appear to be fundamentally involved in the regulation of many physiological processes. The contributions in this monograph thus represent the range of research in the very active investigation of niacin metabolism. The major topics covered are: ??? - Enzymology of ADP-Ribosylation - ADP-Ribosylation and Chromatin Function - Carcinogenesis and Differentiation - NAD Metabolism and Chemotherapy - ADP-Ribosylation and Signal Transduction - Molecular Genetic Approaches to ADP-Ribosylation
Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Author :
Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.:/5 ( download)
Download or read book Zentralblatt Fu R Bakteriologie written by and published by . This book was released on 1989 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sushil K. Sarna
Publisher : Biota Publishing
ISBN 13 : 1615041516
Total Pages : 159 pages
Book Rating : 4.6/5 (15 download)
Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Author :
Publisher : Academic Press
ISBN 13 : 0081026218
Total Pages : 386 pages
Book Rating : 4.0/5 (81 download)
Download or read book Abscisic Acid in Plants written by and published by Academic Press. This book was released on 2019-11-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abscisic Acid in Plants, Volume 92, the latest release in the Advances in Botanical Research series, is a compilation of the current state-of-the-art on the topic. Chapters in this new release comprehensively describe latest knowledge on how ABA functions as a plant hormone. They cover topics related to molecular mechanisms as well as the biochemical and chemical aspects of ABA action: hormone biosynthesis, catabolism, transport, perception, signaling in plants, seeds and in response to biotic and abiotic stresses, hormone evolution and chemical biology, and much more. Presents the latest release in the Advances in Botanical Research series Provides an Ideal resource for post-graduates and researchers in the plant sciences, including plant physiology, plant genetics, plant biochemistry, plant pathology, and plant evolution Contains contributions from internationally recognized authorities in their respective fields
Author : J. Robin Harris
Publisher : Springer
ISBN 13 : 9811336814
Total Pages : 499 pages
Book Rating : 4.8/5 (113 download)
Download or read book Biochemistry and Cell Biology of Ageing: Part II Clinical Science written by J. Robin Harris and published by Springer. This book was released on 2019-03-19 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Author : Byung Hong Kim
Publisher : Cambridge University Press
ISBN 13 : 1107171733
Total Pages : 509 pages
Book Rating : 4.1/5 (71 download)
Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
Author : S.K. Sopory
Publisher : Springer Science & Business Media
ISBN 13 : 1461513650
Total Pages : 328 pages
Book Rating : 4.4/5 (615 download)
Download or read book Signal Transduction in Plants written by S.K. Sopory and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of the mechanisms by which plants perceive environmental cues, both physical and chemical, and transduce the signals that influence specific expression of genes, is an area of intensive scientific research. With the completion of the genome sequence of Arabidopsis it is understood now that a larger number of genes encode for proteins involved in signalling cascades and transcription factors. In this volume, different chapters deal with plant receptors, second messengers like calcium ions, phosphoinositides, salicylic acid and nitrous oxide, calcium binding proteins and kinases. In addition to dealing with the response of plants to light, hormones, pathogens, heat, etc. on cellular activity, work currently going on in apoptosis, cell division, and plastid gene expression is also covered in this book.
Author : Vivian I. Teichberg
Publisher : Springer Science & Business Media
ISBN 13 : 3662226669
Total Pages : 242 pages
Book Rating : 4.6/5 (622 download)
Download or read book Excitatory Amino Acids and Second Messenger Systems written by Vivian I. Teichberg and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the mechanisms through which glutamate, the principal excitatory neurotransmitter in the mammalian central nervous system, modifies neuronal membrane functions and intraneuronal functions. Discussed are the hypothesis that the glutamate receptor signal may be processed by archidonic acid, nitric oxide, Ca 2+ and protein kinases. A key routefor glutamate receptors in synaptic plasticity and neuronal degeneration is beeing increasingly recognized. This is one of the most important new areas of endeavor by neurobiologists. The book, written by some of the most wellknown scientists in this field, provides a comprehensive reviewof conceptual approaches along with experiments showing a link between excitation mediated by glutamate and second messenger systems.
Author : Amitabha Chattopadhyay
Publisher : CRC Press
ISBN 13 : 1420005758
Total Pages : 230 pages
Book Rating : 4.4/5 (2 download)
Download or read book Serotonin Receptors in Neurobiology written by Amitabha Chattopadhyay and published by CRC Press. This book was released on 2007-05-17 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from l
Author : Jonathan Soboloff
Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
