Colonic Motility

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Colonic Motility

Author : Sushil K. Sarna
Publisher : Biota Publishing
ISBN 13 : 1615041516
Total Pages : 159 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Colonic Motility by : Sushil K. Sarna

Download or read book Colonic Motility written by Sushil K. Sarna and published by Biota Publishing. This book was released on 2010-11-01 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.

Colonic Motility

Author : Sushil K. Sarna
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041508
Total Pages : 158 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Colonic Motility by : Sushil K. Sarna

Download or read book Colonic Motility written by Sushil K. Sarna and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood. Table of Contents: Introduction / Regulatory Mechanisms / Colonic Motility in Health / Colonic Motility Dysfunction / References

Clinical and Basic Neurogastroenterology and Motility

Author : Satish S.C. Rao
Publisher : Academic Press
ISBN 13 : 0128130385
Total Pages : 660 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Clinical and Basic Neurogastroenterology and Motility by : Satish S.C. Rao

Download or read book Clinical and Basic Neurogastroenterology and Motility written by Satish S.C. Rao and published by Academic Press. This book was released on 2019-12-01 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field. First of its kind text that covers both basic and clinical aspects, bridging the knowledge gap, and providing a bench to bedside approach for management of common disorders Discusses the latest concepts and basic principles of neurogastroenterology and motility, and how the gut and brain interact in the genesis of functional gastrointestinal and motility disorders Provides an illustrated and practical text on hot topics written by leading adult and pediatric gastroenterology experts across the globe Includes an accompanying more detailed web version of the text with free access to future podcasts

Evaluation of Gastrointestinal Motility and its Disorders

Author : Uday C. Ghoshal
Publisher : Springer
ISBN 13 : 8132208226
Total Pages : 143 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Evaluation of Gastrointestinal Motility and its Disorders by : Uday C. Ghoshal

Download or read book Evaluation of Gastrointestinal Motility and its Disorders written by Uday C. Ghoshal and published by Springer. This book was released on 2016-10-24 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multi-authored book covers most aspects of evaluation of gastrointestinal motility – a field that has been expanding in recent times largely due to advances in diagnostic modalities; coupled with this, new evidences supporting best practices have increased the interest among clinical gastroenterologists, researchers, teachers and trainees in gastrointestinal motility and its disorders. New advances in the field of evaluation of functional bowel diseases and motility disorders, such as high-resolution manometry, 24-h pH impedance monitoring, Bravo capsule pH-metry, barostat, balloon expulsion test, barium and MR defecography, biofeedback, hydrogen breath tests, motility capsule (smartpill) etc. have significantly expanded the scope and outcome of treating these disorders. The chapters have been contributed by a well-conversant group of experts from the global academia, including India, Singapore, Thailand, Korea and Australia, integrating the body of knowledge on evaluation methods with evidence of best practices for the management of motility disorders. A chapter on how to set-up a manometry laboratory provides key information for clinicians and researchers who are planning to start working in this area. With 11 chapters in the book supported with numerous tables, flow charts, schematic diagrams and images, professionals will find it an essential reading.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Gastrointestinal Motility Disorders

Author : Henry P. Parkman
Publisher : W B Saunders Company
ISBN 13 : 9781416050728
Total Pages : 14 pages
Book Rating : 4.0/5 (57 download)

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Book Synopsis Gastrointestinal Motility Disorders by : Henry P. Parkman

Download or read book Gastrointestinal Motility Disorders written by Henry P. Parkman and published by W B Saunders Company. This book was released on 2007 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Gastroenterology Clinics of North America is on Gastrointestinal Motility Disorders. GI motility disorders are common reasons for patients to see gastroenterologists. Knowledge of the pathophysiology, evaluation and treatment of these disorders is important to appropriately care for patients with gastrointestinal motility disorders in clinical practice. The chapters of this issue will discuss key aspects of gastrointestinal motility disorders focusing on how they relate to practicing gastroenterologists and other health care providers. Current knowledge in the area as well as evolving concepts from clinical investigations and translational research from basic sciences will be discussed. The rapid explosion of new technology used in the evaluation of patients will be covered.

Anorectal and Colonic Diseases

Author : Jean-Claude Givel
Publisher : Springer Science & Business Media
ISBN 13 : 3540694196
Total Pages : 818 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Anorectal and Colonic Diseases by : Jean-Claude Givel

Download or read book Anorectal and Colonic Diseases written by Jean-Claude Givel and published by Springer Science & Business Media. This book was released on 2009-11-14 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised new edition focuses on the clinical, diagnostic, and therapeutic aspects of conditions encountered by the coloproctologist and gastroenterological surgeon, who are faced with an increasing number of precise and specific treatment modalities.

Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

GI Motility Testing

Author : Henry P. Parkman
Publisher : SLACK Incorporated
ISBN 13 : 1556429584
Total Pages : 506 pages
Book Rating : 4.5/5 (564 download)

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Book Synopsis GI Motility Testing by : Henry P. Parkman

Download or read book GI Motility Testing written by Henry P. Parkman and published by SLACK Incorporated. This book was released on 2011 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some Chapter Topics Include:

Functional and Motility Disorders of the Gastrointestinal Tract

Author : Brian E. Lacy
Publisher : Springer
ISBN 13 : 1493914987
Total Pages : 285 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Functional and Motility Disorders of the Gastrointestinal Tract by : Brian E. Lacy

Download or read book Functional and Motility Disorders of the Gastrointestinal Tract written by Brian E. Lacy and published by Springer. This book was released on 2014-10-29 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the myriad of functional and motility gastrointestinal disorders in a comprehensive manner. The book is divided into seven major sections, with each section beginning with a brief case presentation highlighting the specific disorder to be reviewed. Appropriate criteria is highlighted, followed by a brief review on the epidemiology, etiology, pathophysiology, diagnosis and treatment of each specific disorder. 2-3 key teaching “pearls”, test questions and key references are also provided for each chapter. The book is organized so that each chapter can stand on its own and be used as a quick reference source in the clinic. Alternatively, it can be read cover to cover as an authoritative textbook on gastrointestinal functional and motility disorders. Written by international experts in the field of motility disorders, Functional and Motility Disorders of the Gastrointestinal Tract: A Case Study Approach is an invaluable resource for experienced physicians, students, residents, fellows, nurse practitioners and physician assistants.

Gastrointestinal Motility

Author : Satish S.C. Rao
Publisher : Springer Science & Business Media
ISBN 13 : 1461548039
Total Pages : 310 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Gastrointestinal Motility by : Satish S.C. Rao

Download or read book Gastrointestinal Motility written by Satish S.C. Rao and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal motility has evolved from an esoteric laboratory tool into a sophisti cated diagnostic technique that is now widely used clinically to guide in management of complex gastrointestinal problems. Today, it is the most rapidly growing subspecialty within gastroenterology. Previously, many of the gastrointestinal motility problems were either ignored or attributed to a disturbance of "psyche." But with the growing knowledge and understanding of how a dysfunction of the gastrointestinal muscle and nerves can cause disease, we are at the threshold of a revolution in our approach to the diagnosis and treatment of gastrointestinal motility disorders. The purpose of this book is to serve as a useful, up-to-date reference manual and guide for the diagnostic and therapeutic approach towards common adult and pediatric gastrointestinal motility problems. In order to enhance the understanding of these disor ders, a problem-oriented approach has been chosen, and wherever possible the authors have provided clinical case scenarios to illustrate their message. The emphasis has been on how to diagnose and treat motility disorders rather than to provide an encyclopedic infor mation. The reference list at the end of each chapter should enable the enthusiast to seek further information. Some of the material presented in this book has been derived from the proceedings of the annual University ofIowa College of Medicine GI Motility Symposia.

The Enteric Nervous System

Author : John Barton Furness
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Enteric Nervous System by : John Barton Furness

Download or read book The Enteric Nervous System written by John Barton Furness and published by . This book was released on 1987 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

GI Surgery Annual

Author : Peush Sahni
Publisher : Springer
ISBN 13 : 9811020108
Total Pages : 237 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis GI Surgery Annual by : Peush Sahni

Download or read book GI Surgery Annual written by Peush Sahni and published by Springer. This book was released on 2017-03-15 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twenty-second volume of GI Surgery Annual covers a gamut of topics from oesophageal adenocarcinoma, to motility disorders of the colon and rectum, mesenteric tumours as well as the contemporary technique of ALPPS, acute portal vein thrombosis and small for size syndrome in live donor liver transplant. The chapter on advances in gastrointestinal surgery as every year reviews the important new information in the field in an easy to understand manner.

Pearls and Tricks in Pediatric Surgery

Author : Martin Lacher
Publisher : Springer Nature
ISBN 13 : 3030510670
Total Pages : 522 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Pearls and Tricks in Pediatric Surgery by : Martin Lacher

Download or read book Pearls and Tricks in Pediatric Surgery written by Martin Lacher and published by Springer Nature. This book was released on 2020-10-29 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing core information on pediatric surgery, this book serves as a supplement to standard pediatric surgical textbooks. It offers pearls of wisdom that will help those who participate in pediatric surgical care, as well as to provide state-of-the-art insights based on physiological principles, literature reviews, and clinical experience. This book is an ideal tool to help readers prepare for questions they will be asked on ward rounds, in the OR, or in oral exams. The depth of exploration is intended for medical students, residents in pediatrics and pediatric surgery, pediatric surgical trainees, pediatric nurse practitioners, primary care pediatricians, and family practitioners.

Advanced Nutrition and Dietetics in Gastroenterology

Author : Miranda Lomer
Publisher : John Wiley & Sons
ISBN 13 : 0470671327
Total Pages : 354 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Advanced Nutrition and Dietetics in Gastroenterology by : Miranda Lomer

Download or read book Advanced Nutrition and Dietetics in Gastroenterology written by Miranda Lomer and published by John Wiley & Sons. This book was released on 2014-08-25 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Nutrition and Dietetics in Gastroenterology provides informative and broad-ranging coverage of the relation between nutrition and diet and the gastrointestinal tract. It explores dietary factors involved in causation of a variety of gastrointestinal disorders, as well as the effects on diet and the treatments available. It also provides an overview of anatomy and physiology, measurement and assessment of function, and dietary components relevant to gastrointestinal health. ABOUT THE SERIES Dietary recommendations need to be based on solid evidence, but where can you find this information? The British Dietetic Association and the publishers of the Manual of Dietetic Practice present an essential and authoritative reference series on the evidence base relating to advanced aspects of nutrition and diet in selected clinical specialties. Each book provides a comprehensive and critical review of key literature in its subject. Each covers established areas of understanding, current controversies and areas of future development and investigation, and is oriented around six key themes: •Disease processes, including metabolism, physiology, and genetics •Disease consequences, including morbidity, mortality, nutritional epidemiology and patient perspectives •Nutritional consequences of diseases •Nutritional assessment, drawing on anthropometric, biochemical, clinical, dietary, economic and social approaches •Clinical investigation and management •Nutritional and dietary management •Trustworthy, international in scope, and accessible, Advanced Nutrition and Dietetics is a vital resource for a range of practitioners, researchers and educators in nutrition and dietetics, including dietitians, nutritionists, doctors and specialist nurses.

The ASCRS Manual of Colon and Rectal Surgery

Author : David E. Beck
Publisher : Springer Science & Business Media
ISBN 13 : 0387734406
Total Pages : 1042 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis The ASCRS Manual of Colon and Rectal Surgery by : David E. Beck

Download or read book The ASCRS Manual of Colon and Rectal Surgery written by David E. Beck and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ASCRS Textbook of Surgery of the Colon and Rectum offers a comprehensive textbook designed to provide state of the art information to residents in training and fully trained surgeons seeking recertification. The textbook also supports the mission of the ASCRS to be the world’s authority on colon and rectal disease. The combination of junior and senior authors selected from the membership of the ASCRS for each chapter will provide a comprehensive summary of each topic and allow the touch of experience to focus and temper the material. This approach should provide the reader with a very open minded, evidence based approach to all aspects of colorectal disease. Derived from the textbook, The ASCRS Manual of Surgery of the Colon and Rectum offers a “hands on” version of the textbook, written with the same comprehensive, evidence-based approach but distilled to the clinical essentials. In a handy pocket format, readers will find the bread and butter information for the broad spectrum of practice. In a consistent style, each chapter outlines the condition or procedure being discussed in a concise outline format – easy to read, appropriately illustrated and referenced.

Gastrointestinal Motility

Author : N. W. Read
Publisher : Routledge
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gastrointestinal Motility by : N. W. Read

Download or read book Gastrointestinal Motility written by N. W. Read and published by Routledge. This book was released on 1989 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders of gastrointestinal motor function have been the subject of research for almost a century, but it is only in the last 20 years that real advances have been made in the understanding of this important area. Gastrointestinal motility, today, is a science which provides invaluable insights into the mechanisms, diagnosis and management of gastrointestinal disease.