Chemistry and Biological Actions of 4-Nitroquinoline 1-Oxide

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Publisher : Springer Science & Business Media
ISBN 13 : 3642492819
Total Pages : 164 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Chemistry and Biological Actions of 4-Nitroquinoline 1-Oxide by : H. Endo

Download or read book Chemistry and Biological Actions of 4-Nitroquinoline 1-Oxide written by H. Endo and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decade a considerable body of knowledge has come into existence concerning a class of carcinogenic molecules chiefly represented by 4-nitroquinoline i-oxide. Original papers on this subject are numerous and widely scattered over many branches of science; it was felt that these papers should be reviewed and the knowledge brought together in one volume before it became too unwieldy. This we have attempted to do in this monograph. Our aim has been to include all relevant papers published to date, so that it may serve as an epitome of the present status of knowledge on this important subject. We have been fortunate in securing the cooperation of several colleagues who have contributed chapters, each dealing with one aspect of the subject. We have been doubly fortunate in that these contributors, like ourselves, were at one time or another members of the group belonging to the scientific staff of Dr. WARO NAKA HARA, Director of the National Cancer Center Research Institute, Tokyo, Japan.

Chemistry and biological actions of 4-nitroquinoline 1-oxide

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Publisher :
ISBN 13 :
Total Pages : 101 pages
Book Rating : 4.:/5 (7 download)

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Book Synopsis Chemistry and biological actions of 4-nitroquinoline 1-oxide by : H. Endo

Download or read book Chemistry and biological actions of 4-nitroquinoline 1-oxide written by H. Endo and published by . This book was released on 1971 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Nitroquinolines

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Author :
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Nitroquinolines by : Takashi Sugimura

Download or read book The Nitroquinolines written by Takashi Sugimura and published by Raven Press (ID). This book was released on 1981 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Total Synthesis of Natural Products

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Publisher : John Wiley & Sons
ISBN 13 : 047012959X
Total Pages : 720 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Total Synthesis of Natural Products by : John ApSimon

Download or read book The Total Synthesis of Natural Products written by John ApSimon and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemistry's innovative breadth is especially noteworthy in the area of natural products synthesis. Since the early 1970s, this landmark chemical reference has been documenting the newest and most important of these, in a readily understood format, that clearly traces each of their synthetic routes. Volume Eight, the latest in the series, contains a long-awaited look at the synthesis of tri- and tetracyclic diterpenes, along with the synthesis of naturally occurring quinones. Recent interest in the biologically important polysaccharides has led to a detailed consideration of that compound class. Finally, this new volume contains a look at the strategies and methods specific to natural products containing the spiroketal functional group. The Total Synthesis of Natural Products, Volume Eight, continues the meticulous work of the series, providing chemists with an entirely up-to-date and convenient guide to the critical new syntheses essential to organic chemistry's continuing evolution.

Environmental Health Perspectives

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Publisher :
ISBN 13 :
Total Pages : 580 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1986 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Objective

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Publisher :
ISBN 13 :
Total Pages : 310 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis Objective by : National Cancer Institute (U.S.)

Download or read book Objective written by National Cancer Institute (U.S.) and published by . This book was released on 1973 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anticancer Drug Development

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Publisher : Elsevier
ISBN 13 : 0080490441
Total Pages : 411 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Anticancer Drug Development by : Bruce C. Baguley

Download or read book Anticancer Drug Development written by Bruce C. Baguley and published by Elsevier. This book was released on 2001-11-17 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching

Journal of the Chemical Society

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Publisher :
ISBN 13 :
Total Pages : 1188 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Journal of the Chemical Society by : Chemical Society (Great Britain)

Download or read book Journal of the Chemical Society written by Chemical Society (Great Britain) and published by . This book was released on 1892 with total page 1188 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Titles of chemical papers in British and foreign journals" included in Quarterly journal, v. 1-12.

Quarterly Journal of the Chemical Society of London

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Publisher :
ISBN 13 :
Total Pages : 788 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Quarterly Journal of the Chemical Society of London by : Chemical Society (Great Britain)

Download or read book Quarterly Journal of the Chemical Society of London written by Chemical Society (Great Britain) and published by . This book was released on 1890 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Metabolic Activation of 4-nitroquinoline-1-oxide

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Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.:/5 (778 download)

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Book Synopsis The Metabolic Activation of 4-nitroquinoline-1-oxide by : Nancy A. Lorr

Download or read book The Metabolic Activation of 4-nitroquinoline-1-oxide written by Nancy A. Lorr and published by . This book was released on 1981 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reactive Drug Metabolites

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Publisher : John Wiley & Sons
ISBN 13 : 352765576X
Total Pages : 445 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Reactive Drug Metabolites by : Amit S. Kalgutkar

Download or read book Reactive Drug Metabolites written by Amit S. Kalgutkar and published by John Wiley & Sons. This book was released on 2012-09-06 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of herbal constituents and IADRs. The next part covers current strategies and approaches to evaluate the reactive metabolite potential of new drug candidates, both by predictive and by bioanalytical methods. There then follows an in-depth analysis of the toxicological potential of the top 200 prescription drugs, illustrating the power and the limits of the toxicophore concept, backed by numerous case studies. Finally, a risk-benefi t approach to managing the toxicity risk of reactive metabolite-prone drugs is presented. Since the authors carefully develop the knowledge needed, from fundamental considerations to current industry standards, no degree in pharmacology is required to read this book, making it perfect for medicinal chemists without in-depth pharmacology training.

Advances in Heterocyclic Chemistry

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Publisher : Elsevier
ISBN 13 : 0080493610
Total Pages : 369 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Elsevier. This book was released on 2004-04-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area, one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

Journal of the American Chemical Society

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Publisher :
ISBN 13 :
Total Pages : 1602 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Journal of the American Chemical Society by : American Chemical Society

Download or read book Journal of the American Chemical Society written by American Chemical Society and published by . This book was released on 1951-04 with total page 1602 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical & Pharmaceutical Bulletin

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Publisher :
ISBN 13 :
Total Pages : 764 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Chemical & Pharmaceutical Bulletin by :

Download or read book Chemical & Pharmaceutical Bulletin written by and published by . This book was released on 1962 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Quinolines

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Publisher :
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis Quinolines by : Gurnos Jones

Download or read book Quinolines written by Gurnos Jones and published by . This book was released on 1977 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dictionary of Organic Compounds

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Publisher : CRC Press
ISBN 13 : 9780412540905
Total Pages : 1056 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Dictionary of Organic Compounds by :

Download or read book Dictionary of Organic Compounds written by and published by CRC Press. This book was released on 1996 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nitro Compounds: Advances in Research and Application: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464968918
Total Pages : 85 pages
Book Rating : 4.4/5 (649 download)

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Download or read book Nitro Compounds: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-02-14 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitro Compounds: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Nitro Compounds in a concise format. The editors have built Nitro Compounds: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nitro Compounds in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nitro Compounds: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.