The Neurobiology of Schizophrenia

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Author :
Publisher : Academic Press
ISBN 13 : 0128018771
Total Pages : 470 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Neurobiology of Schizophrenia by : Ted Abel

Download or read book The Neurobiology of Schizophrenia written by Ted Abel and published by Academic Press. This book was released on 2016-07-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Neurological, Psychiatric, and Developmental Disorders

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Publisher : National Academies Press
ISBN 13 : 0309170931
Total Pages : 458 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neurological, Psychiatric, and Developmental Disorders by : Institute of Medicine

Download or read book Neurological, Psychiatric, and Developmental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.

The Neurology of Schizophrenia

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Author :
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Neurology of Schizophrenia by : Henry A. Nasrallah

Download or read book The Neurology of Schizophrenia written by Henry A. Nasrallah and published by Elsevier Publishing Company. This book was released on 1986 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting the handbook series with a volume on the neurology of schizophrenia is obviously an appropriate choice. The volume presents the scientific evidence for the neurological basis of the schizophrenia syndrome. Not only are facts presented, but also many conceptual frameworks for defining subtypes of schizophrenia and relating clinical phenomenological findings to disorders of brain structure and function in schizophrenia. Chapters 1 to 8 flow in roughly the same sequence as a neurologist examining a schizophrenic patient: history, physical examination, differential diagnosis, laboratory tests, EEG, evoked potentials, neuropsychological testing etc. are dealt with. Chapters 9 to 13 cover the state of the art in brain imaging findings in schizophrenia using the various techniques available to us. Other chapters cover theoretical models of schizophrenia based on current neuropathological findings and provide a framework for future direction in research.

The Neuropathology of Schizophrenia

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Publisher :
ISBN 13 :
Total Pages : 402 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis The Neuropathology of Schizophrenia by : Paul J. Harrison

Download or read book The Neuropathology of Schizophrenia written by Paul J. Harrison and published by . This book was released on 2000-08-24 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.

Neurobiology of Mental Illness

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Publisher : Oxford University Press, USA
ISBN 13 : 0199934959
Total Pages : 1259 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Neurobiology of Mental Illness by : Dennis S. Charney

Download or read book Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press, USA. This book was released on 2013-07-04 with total page 1259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Secondary Schizophrenia

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Publisher : Cambridge University Press
ISBN 13 : 1139485229
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Secondary Schizophrenia by : Perminder S. Sachdev

Download or read book Secondary Schizophrenia written by Perminder S. Sachdev and published by Cambridge University Press. This book was released on 2010-02-04 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.

Mind, Brain, and Schizophrenia

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Publisher : Oxford University Press
ISBN 13 : 0195176375
Total Pages : 293 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Mind, Brain, and Schizophrenia by : Peter Williamson

Download or read book Mind, Brain, and Schizophrenia written by Peter Williamson and published by Oxford University Press. This book was released on 2006 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, molecular genetics and brain imaging have guided efforts to find the causes of schizophrenia. It is becoming increasingly clear that many genes are involved in schizophrenia and that they interact with other factors in very complex ways, which have not yet been elucidated. Neuroimaging techniques have allowed scientists and physicians to examine brain structure, function, and chemistry in living patients with schizophrenia but results so far have been disappointing. No two patients seem to share exactly the same combination of clinical symptoms or physical findings. Yet all have the syndrome recognized as schizophrenia. The author of this accessible, well-written book argues that it is time to set aside the search for a single cause of schizophrenia and focus on the disease's final common pathway. He highlights clues from a wide range of research, including neurotransmitter, psychophysiological, and brain imaging studies. He then describes possibilities for the final common pathway at an understandable level in the context of what is already known about schizophrenia. While there are no preferred models of schizophrenia, a pattern is emerging which implicates those structures in the brain known to be important in integrating perception, cognition, and affect. A better understanding of these processes will be critical for developing more effective treatments. This book will help advance that effort. It will be of great value to psychiatrists, psychologists, neurologists, neuroimagers, and basic scientists working in the field of schizophrenia research, and to their students and trainees. It will also be of interest to clinicians and scientists concerned with other neuropsychiatric disorders, and to the families of those diagnosed with schizophrenia.

Charney & Nestler's Neurobiology of Mental Illness

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Author :
Publisher : Oxford University Press
ISBN 13 : 019068142X
Total Pages : 1025 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Charney & Nestler's Neurobiology of Mental Illness by : Dennis S. Charney

Download or read book Charney & Nestler's Neurobiology of Mental Illness written by Dennis S. Charney and published by Oxford University Press. This book was released on 2018 with total page 1025 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text. In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit. Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress. The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.

Schizophrenia

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Publisher :
ISBN 13 : 9780198525967
Total Pages : 438 pages
Book Rating : 4.5/5 (259 download)

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Book Synopsis Schizophrenia by : Stephen M. Lawrie

Download or read book Schizophrenia written by Stephen M. Lawrie and published by . This book was released on 2004 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging techniques have made a huge contribution to our understanding of schizophrenia and other neuropsychiatric disorders. Until now however, texts on both schizophrenia and neuroimaging have paid little attention to the overlap between these areas. This new volume is the first dedicated to unravelling how these techniques can help us better understand this complex disorder. Each chapter focuses on a particular research method, describing the nature of the findings, the main technological problems, and future possibilities. Though including sufficient methodological detail to be of value to imaging researchers, the emphasis throughout is on providing information of value to clinicians. Written and edited by leaders in schizophrenia research, this book details what structural and functional brain imaging studies have already established about schizophrenia and what developments are likely in the foreseeable future.

Neuroimaging in Schizophrenia

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Publisher : Springer Nature
ISBN 13 : 3030352064
Total Pages : 432 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Neuroimaging in Schizophrenia by : Marek Kubicki

Download or read book Neuroimaging in Schizophrenia written by Marek Kubicki and published by Springer Nature. This book was released on 2020-02-18 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.

Cognitive and Behavioral Dysfunction in Schizophrenia

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Publisher : Academic Press
ISBN 13 : 0323903061
Total Pages : 218 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Cognitive and Behavioral Dysfunction in Schizophrenia by : Ahmed A. Moustafa

Download or read book Cognitive and Behavioral Dysfunction in Schizophrenia written by Ahmed A. Moustafa and published by Academic Press. This book was released on 2021-06-13 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, schizophrenia affects more than 21 million people worldwide, causing distortions in thinking, perception, emotions, language, sense of self, behavior, and hallucinations. Cognitive and Behavioral Dysfunction in Schizophrenia provides an overview of topics and theories related to cognitive dysfunction in schizophrenia. This book discusses what schizophrenia is and its relationship with the cognitive domains including, but not limited to, learning, working memory, attention, and both deductive and inductive reasoning. This book also reviews theories as to why some individuals develop schizophrenia following cannabis and amphetamine abuse and how these relate to additional cognitive problems. The book further discusses recent topics related to religious delusions in psychotic patients, impact of sleep on psychosis, how urban life increases the likelihood of developing schizophrenia, as well as sexual dysfunction in schizophrenia patients. Unlike other books, Cognitive and Behavioral Dysfunction in Schizophrenia covers many cognitive domains related to the occurrence and development of positive and negative symptoms of schizophrenia. Advanced students and researchers in cognitive and behavioral neuroscience, psychology, psychiatry, and psychotherapy will find it useful for a well-rounded understanding of the subject. Covers neural and behavioral studies addressing the symptomology of schizophrenia Discusses recent studies of the relationship between cognition and schizophrenia symptoms Reviews the development of schizophrenia due to genetic and environmental factors

Advances in the Neurobiology of Schizophrenia

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Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Advances in the Neurobiology of Schizophrenia by : Johan A. den Boer

Download or read book Advances in the Neurobiology of Schizophrenia written by Johan A. den Boer and published by . This book was released on 1995-07-11 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed major advances in the study of neuroscience which have increased our understanding of the relationship between cerebral processes and behavioural, cognitive and emotional disorders. This series aims to monitor important research developments in the field of biological psychiatry and their relevance to clinical practice. Since the 1950s there has been significant progress in our understanding of the neurobiology of schizophrenia. This important volume illustrates these new developments, particularly in terms of pharmacotherapeutics, pathogenesis and research methodology. Eminent scientists from around the world discuss conceptual issues, epidemiology, genetic analysis of psychotic disturbances, neuropathological changes and brain imaging studies, atypical neuroleptics, psychopharmacology of schizophrenia, neuropeptide involvement, neurophysiology and information processing in schizophrenia. Also highlighted are the similarities between childhood developmental disorders and schizophrenia, as well as the relatively neglected area of biological factors in childhood psychosis and their predictive value in adult psychopathology. Psychiatrists, neuroscientists, pharmacologists, psychologists, physicians and general practitioners will find this authoritative state-of-the-art review important and informative reading.

The Epidemiology of Schizophrenia

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Publisher : Cambridge University Press
ISBN 13 : 9780521121026
Total Pages : 0 pages
Book Rating : 4.1/5 (21 download)

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Book Synopsis The Epidemiology of Schizophrenia by : Robin M. Murray

Download or read book The Epidemiology of Schizophrenia written by Robin M. Murray and published by Cambridge University Press. This book was released on 2009-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.

Arousal in Neurological and Psychiatric Diseases

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Publisher : Academic Press
ISBN 13 : 0128179937
Total Pages : 276 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Arousal in Neurological and Psychiatric Diseases by : Edgar Garcia-Rill

Download or read book Arousal in Neurological and Psychiatric Diseases written by Edgar Garcia-Rill and published by Academic Press. This book was released on 2019-06-18 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism

The Neuroscience of Clinical Psychiatry

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1469802007
Total Pages : 334 pages
Book Rating : 4.4/5 (698 download)

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Book Synopsis The Neuroscience of Clinical Psychiatry by : Edmund S. Higgins

Download or read book The Neuroscience of Clinical Psychiatry written by Edmund S. Higgins and published by Lippincott Williams & Wilkins. This book was released on 2012-11-05 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing the latest breakthroughs in neuroscience to the clinician, this text provides resident and practicing psychiatrists with a comprehensive, clinically relevant overview of the brain mechanisms underlying behavior and mental illness. The book presents an integrated perspective on the structures and workings of the brain, the mechanisms governing behaviors such as pleasure, aggression, and intelligence, and the pathophysiology of mental disorders. More than 200 two-color illustrations clarify key concepts. Questions and answers at the end of each chapter facilitate review and board preparation. Readers will also have online access to the complete, fully searchable text and a quiz bank of over 150 questions at www.neuroscienceofclinicalpsychiatry.com.

Schizophrenia and Psychotic Spectrum Disorders

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Publisher : Oxford University Press
ISBN 13 : 019937807X
Total Pages : 401 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Schizophrenia and Psychotic Spectrum Disorders by : S. Charles Schulz

Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.

In Search of Madness

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Publisher : Oxford University Press
ISBN 13 : 9780195352795
Total Pages : 388 pages
Book Rating : 4.3/5 (527 download)

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Book Synopsis In Search of Madness by : R. Walter Heinrichs

Download or read book In Search of Madness written by R. Walter Heinrichs and published by Oxford University Press. This book was released on 2001-03-29 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, scientific articles on schizophrenia have doubled in number, and prophecies of breakthrough have appeared and receded. The result is a scattered and confusing mass of evidence that is difficult to evaluate. How much progress has really been made? Are the neurological causes of madness truly in sight? This book evaluates the progress of schizophrenia science by summarizing what is known about how patients with the illness differ from healthy people. The tools of meta-analysis are first explained and then employed to make the strength and consistency of these differences explicit. Beginning with the study of symptoms, then moving through the search for objective disease markers, findings on the cognitive functions, structure, physiology, chemistry, and development of the brain, this book is a journey into the enigma of madness and its science. What emerges is an illness that reveals itself most strongly in thought processes, not biology. As evidence actually becomes weaker and harder to reproduce as research moves from mind to molecule, the harvest of dazzling research techniques turns out to be modest or inconsistent. Schizophrenia is an anomaly at the frontier of mind and brain, but In Search of Madness points the way to its solution.