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Author : Ernest Frederick Gale
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.:/5 (43 download)
Download or read book The Molecular Basis of Antibiotic Action written by Ernest Frederick Gale and published by John Wiley & Sons. This book was released on 1981 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : T. J. Franklin
Publisher : Springer Science & Business Media
ISBN 13 : 1475745990
Total Pages : 173 pages
Book Rating : 4.4/5 (757 download)
Download or read book Biochemistry and Molecular Biology of Antimicrobial Drug Action written by T. J. Franklin and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.
Author : Trevor J. Franklin
Publisher : Springer Science & Business Media
ISBN 13 : 0387225544
Total Pages : 188 pages
Book Rating : 4.3/5 (872 download)
Download or read book Biochemistry and Molecular Biology of Antimicrobial Drug Action written by Trevor J. Franklin and published by Springer Science & Business Media. This book was released on 2005-03-03 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309030447
Total Pages : 393 pages
Book Rating : 4.3/5 (9 download)
Download or read book The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds written by National Research Council and published by National Academies Press. This book was released on 1980-02-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Boyan B. Bonev
Publisher : John Wiley & Sons
ISBN 13 : 1119558204
Total Pages : 288 pages
Book Rating : 4.1/5 (195 download)
Download or read book Bacterial Resistance to Antibiotics written by Boyan B. Bonev and published by John Wiley & Sons. This book was released on 2019-03-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
Author : Jun Lin
Publisher : Frontiers Media SA
ISBN 13 : 2889195260
Total Pages : 226 pages
Book Rating : 4.8/5 (891 download)
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Author : Douglas L. Mayers
Publisher : Springer
ISBN 13 : 3319467182
Total Pages : 773 pages
Book Rating : 4.3/5 (194 download)
Download or read book Antimicrobial Drug Resistance written by Douglas L. Mayers and published by Springer. This book was released on 2017-06-19 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes included in Antimicrobial Drug Resistance, Second Edition is an updated, comprehensive and multidisciplinary reference covering the area of antimicrobial drug resistance in bacteria, fungi, viruses, and parasites from basic science, clinical, and epidemiological perspectives. This newly revised compendium reviews the most current research and development on drug resistance while still providing the information in the accessible format of the first edition. The first volume, Antimicrobial Drug Resistance: Mechanisms of Drug Resistance, is dedicated to the biological basis of drug resistance and effective avenues for drug development. With the emergence of more drug-resistant organisms, the approach to dealing with the drug resistance problem must include the research of different aspects of the mechanisms of bacterial resistance and the dissemination of resistance genes as well as research utilizing new genomic information. These approaches will permit the design of novel strategies to develop new antibiotics and preserve the effectiveness of those currently available. The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. Although there is evidence that restricted use of a specific antibiotic can be followed by a decrease in drug resistance to that agent, drug resistance control is not easily achieved. Thus, the infectious diseases physician requires input from the clinical microbiologist, antimicrobial stewardship personnel, and infection control specialist to make informed choices for the effective management of various strains of drug-resistant pathogens in individual patients. This 2-volume set is an important reference for students in microbiology, infectious diseases physicians, medical students, basic scientists, drug development researchers, microbiologists, epidemiologists, and public health practitioners.
Author : G.G. Gallo
Publisher : Springer Science & Business Media
ISBN 13 : 147579200X
Total Pages : 283 pages
Book Rating : 4.4/5 (757 download)
Download or read book Antibiotics written by G.G. Gallo and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this translation of the Italian second edition, the authors provide a comprehensive account of the current knowledge on antibiotics. They concisely describe how various scientific disciplines are involved in antibiotics research, development, and use. Their work also discusses the industrial and clinical development of new antibiotics, as well as the questions and controversies related to the function of antibiotics in nature. Antibiotics is richly illustrated with clear chemical structures, drawings, diagrams, and synoptical tables.
Author : Christine Zuchora-Walske
Publisher : ABDO
ISBN 13 : 1617839019
Total Pages : 114 pages
Book Rating : 4.6/5 (178 download)
Download or read book Antibiotics written by Christine Zuchora-Walske and published by ABDO. This book was released on 2014-09-01 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amazing medical breakthroughs are made every day. In the past decades, medical researchers have cured diseases that were once deadly and devised new methods to heal that were once unimaginable. This title follows the development of antibiotics, including premodern forerunners to antibiotics, groundbreaking discoveries and the doctors who made them, and where the science is heading in the future. Learn how antibiotics work and why scientists need to continually discover new drugs. Sidebars, full-color photos, a glossary, and well-placed graphs, charts, and maps, enhance this engaging title. Aligned to Common Core Standards and correlated to state standards. Essential Library is an imprint of ABDO Publishing Company.
Author : José-Luis Capelo-Martínez
Publisher : John Wiley & Sons
ISBN 13 : 1119282527
Total Pages : 730 pages
Book Rating : 4.1/5 (192 download)
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Author : Carlos F. Amábile-Cuevas
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 ( download)
Download or read book Antibiotic Resistance written by Carlos F. Amábile-Cuevas and published by Landes Bioscience. This book was released on 1996 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Allan Denver Russell
Publisher : Ellis Horwood Limited
ISBN 13 : 9780131248274
Total Pages : 292 pages
Book Rating : 4.2/5 (482 download)
Download or read book Understanding Antibacterial Action and Resistance written by Allan Denver Russell and published by Ellis Horwood Limited. This book was released on 1996-01-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Henri Grosjean
Publisher : CRC Press
ISBN 13 : 1498713157
Total Pages : 682 pages
Book Rating : 4.4/5 (987 download)
Download or read book DNA and RNA Modification Enzymes written by Henri Grosjean and published by CRC Press. This book was released on 2009-06-11 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a short ‘conclusion and future prospect’ section and an exhaustive list of 35 to up to 257 references (in average 87). Contributors are geneticists, structural enzymologists and molecular biologists working at the forefront of this exciting, fast-moving and diverse field of researches. This book will be a major interest to PhD students and University teachers alike. It will also serve as an invaluable reference tool for new researchers in the field, as well as for specialists of RNA modification enzymes generally not well informed about what is going on in similar processes acting on DNA and vice-versa for specialists of the DNA modification-editing and repair processes usually not much acquainted with what is going on in the RNA maturation field. The book is subdivided into 41 chapters (740 pages). The common links between them are mainly the enzymatic aspects of the different modification-editing and repair machineries: structural, mechanistic, functional and evolutionary aspects. It starts with two general and historical overview of the discovery of modified nucleosides in DNA and RNA and corresponding modification-editing enzymes. Then follows eleven chapters on DNA modification and editing (mechanistic and functional aspects). Two additional chapters cover problems related to DNA/RNA repair and base editing by C-to-U deaminases, followed by three chapters on RNA editing by C-to-U and A-to-I type of deamination. Discussions about interplay between DNA and RNA modifications and the emergence of DNA are covered in two independent chapters, followed by twenty chapters on different but complementary aspects of RNA modification enzymes and their cellular implications. The last chapter concerns the description of the present state-of-the art for incorporating modified nucleosides by in vitro chemical synthesis. At the end of the book, six appendicies give useful details on modified nucleosides, modification-editing enzymes and nucleosides analogs. This information is usually difficult to obtain from current scientific literature.
Author : Trevor John Franklin
Publisher : Springer
ISBN 13 : 148993412X
Total Pages : 235 pages
Book Rating : 4.4/5 (899 download)
Download or read book Biochemistry of Antimicrobial Action written by Trevor John Franklin and published by Springer. This book was released on 2013-11-11 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division. The use of antimicrobial agents as highly specific inhibitors has in turn substantially assisted the investigation of complex biochemical processes. The literature in this field is so extensive however, that we considered an attempt should be made to draw together in an introductory book the more significant studies of recent years. This book, which is in fact based on lecture courses given by us to undergraduates at Liverpool and Manchester Universities, is therefore intended as an introduction to the biochemistry of antimicrobial action for advanced students in many disciplines. We hope that it may also be useful to established scientists who are new to this area of research. The book is concerned with a discussion of medically important antimicrobial compounds and also a number of agents that, although having no medical uses, have proved invaluable as research tools in biochemistry. Our aim has been to present the available information in a simple and readable way, emphasizing the established facts rather than more controversial material. Whenever possible, however, we have indicated the gaps in the present knowledge of the subject where further information is required.
Author : M.I. Page
Publisher : Springer
ISBN 13 : 9789401053006
Total Pages : 0 pages
Book Rating : 4.0/5 (53 download)
Download or read book The Chemistry of β-Lactams written by M.I. Page and published by Springer. This book was released on 2012-10-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309131219
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)
Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Author : Claudio O. Gualerzi
Publisher : John Wiley & Sons
ISBN 13 : 3527659706
Total Pages : 549 pages
Book Rating : 4.5/5 (276 download)
Download or read book Antibiotics written by Claudio O. Gualerzi and published by John Wiley & Sons. This book was released on 2013-09-05 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.
