Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
The Microfluidic Intravital Window
Download The Microfluidic Intravital Window full books in PDF, epub, and Kindle. Read online The Microfluidic Intravital Window ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis CMOS Biomicrosystems by : Krzysztof Iniewski
Download or read book CMOS Biomicrosystems written by Krzysztof Iniewski and published by John Wiley & Sons. This book was released on 2011-10-14 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will address the-state-of-the-art in integrated Bio-Microsystems that integrate microelectronics with fluidics, photonics, and mechanics. New exciting opportunities in emerging applications that will take system performance beyond offered by traditional CMOS based circuits are discussed in detail. The book is a must for anyone serious about microelectronics integration possibilities for future technologies. The book is written by top notch international experts in industry and academia. The intended audience is practicing engineers with electronics background that want to learn about integrated microsystems. The book will be also used as a recommended reading and supplementary material in graduate course curriculum.
Book Synopsis Cell Migration in Three Dimensions by : Coert Margadant
Download or read book Cell Migration in Three Dimensions written by Coert Margadant and published by Springer Nature. This book was released on 2023-01-18 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed collection serves as a unique and excellent collection of state-of-the-art methods and protocols to interrogate cell migration in a wide variety of different contexts and model organisms, as well as advanced image analysis and quantitative assessment of a diverse array of parameters related to cell migration. The book focuses on the cell biology of cell migration, developmental model systems to assess cell migration during morphogenesis, cell migration in cancers and the tumor micro-environment, as well as blood vessel formation and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell Migration in Three Dimensions provides a solid foundation for scientists of different disciplines to investigate cell migration in biological processes. Chapters 7, 12, 16, 17, 19, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis Target Discovery and Validation by : Alleyn T. Plowright
Download or read book Target Discovery and Validation written by Alleyn T. Plowright and published by John Wiley & Sons. This book was released on 2020-02-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.
Book Synopsis Regenerative Medicine Technology by : Sean V. Murphy
Download or read book Regenerative Medicine Technology written by Sean V. Murphy and published by CRC Press. This book was released on 2016-11-30 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miniaturization in the fields of chemistry and molecular biology has resulted in the "lab-on-a-chip." Such systems are micro-fabricated devices capable of handling extremely small fluid volumes facilitating the scaling of single or multiple lab processes down to a microchip-sized format. The convergence of lab-on-a-chip technology with the field of cell biology facilitated the development of "organ-on-a-chip" systems. Such systems simulate the function of tissues and organs, having the potential to bypass some cell and animal testing methods. These technologies have generated high interest as applications for disease modeling and drug discovery. This book, edited by Drs. Sean Murphy and Anthony Atala, provides a comprehensive coverage of the technologies that have been used to develop organ-on-a-chip systems. Known leaders cover the basics to the most relevant and novel topics in the field, including micro-fabrication, 3D bio-printing, 3D cell culture techniques, biosensor design and microelectronics, micro-fluidics, data collection, and predictive analysis. The book describes specific tissue types amenable for disease modeling and drug discovery applications. Lung, liver, heart, skin and kidney "on-a-chip" technologies are included as well as a progress report on designing an entire "body-on-a-chip" system. Additionally, the book covers applications of various systems for modeling tissue-specific cancers, metastasis, and tumor microenvironments; and provides an overview of current and potential applications of these systems to disease modeling, toxicity testing, and individualized medicine.
Book Synopsis Tumor Microenvironment by : Alexander Birbrair
Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer Nature. This book was released on 2021-10-18 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
Book Synopsis Revisiting Seed and Soil: A New Approach to Target Hibernating Dormant Tumor Cells, 2nd edition by : Dalit Barkan
Download or read book Revisiting Seed and Soil: A New Approach to Target Hibernating Dormant Tumor Cells, 2nd edition written by Dalit Barkan and published by Frontiers Media SA. This book was released on 2023-03-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastasis is the major cause of mortality in cancer patients. Metastases can be present at the time of diagnosis or can occur years or decades after the removal of the primary tumor and treatment. This long latency in the manifestation of recurrent metastatic disease is explained clinically by the persistence of quiescent tumor cells that disseminated early in the course of the disease from the primary tumor to select distant organs. These residing disseminated tumor cells (DTCs) at distant organs lay dormant and asymptomatic until reawakened to form overt metastases. Importantly, the quiescent nature of these “hibernating” DTCs facilitates their resistance to conventional therapies that target actively dividing tumor cells. Therefore, unraveling the biology of dormancy and reactivation of the residing DTCs to life-threatening lesions is of utmost importance in order to develop new therapeutic strategies to prevent the recurrent metastatic disease from ever emerging or to better treat these recurrent cancers. The mechanisms underlying the biology of tumor dormancy and their reactivation to overt metastases are just beginning to emerge thanks to a growing appreciation of the potentially chronic nature of some cancers and the development of experimental model systems for their study. In this Research Topic, we will follow the journey of circulating tumor cells (CTCs) dispatching from the primary site until their successful lodging into a new and foreign site to become DTCs. We will explore the intrinsic mechanisms along with microenvironmental cues and niches that they encounter during their journey that may dictate their fate.
Book Synopsis Engineering and Physical Approaches to Cancer by : Ian Y. Wong
Download or read book Engineering and Physical Approaches to Cancer written by Ian Y. Wong and published by Springer Nature. This book was released on 2023-04-11 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry. Describes physical aspects of cancer, including collective cell migration, the aberrant tumor microenvironment, circulating tumor cells, and metastatic colonization. First volume available on the topic of physical aspects of cancer
Book Synopsis Imaging from Cells to Animals In Vivo by : Margarida Barroso
Download or read book Imaging from Cells to Animals In Vivo written by Margarida Barroso and published by CRC Press. This book was released on 2020-12-03 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging from Cells to Animals In Vivo offers an overview of optical imaging techniques developed over the past two decades to investigate biological processes in live cells and tissues. It comprehensively covers the main imaging approaches used as well as the application of those techniques to biological investigations in preclinical models. Among the areas covered are cell metabolism, receptor-ligand interactions, membrane trafficking, cell signaling, cell migration, cell adhesion, cytoskeleton and other processes using various molecular optical imaging techniques in living organisms, such as mice and zebrafish. Features Brings together biology and advanced optical imaging techniques to provide an overview of progress and modern methods from microscopy to whole body imaging. Fills the need for a comprehensive view of application-driven development and use of new tools to ask new biological questions in the context of a living system. Includes basic chapters on key methods and instrumentation, from fluorescence microscopy and imaging to endoscopy, optical coherence tomography and super-resolution imaging. Discusses approaches at different length scales and biomedical applications to the study of single cell, whole organ, and whole organism behavior. Addresses the impact on discovery, such as cellular function as implicated in human disease and translational medicine, for example in cancer diagnosis.
Book Synopsis Revisiting the Metastatic Cascade: Putting Myeloid Cells Into Context by : George S. Karagiannis
Download or read book Revisiting the Metastatic Cascade: Putting Myeloid Cells Into Context written by George S. Karagiannis and published by Frontiers Media SA. This book was released on 2021-02-09 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathobiology of Human Disease written by and published by Elsevier. This book was released on 2014-08-01 with total page 4376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Book Synopsis Pancreas Imaging Across the Spectrum by : Amelia K. Linnemann
Download or read book Pancreas Imaging Across the Spectrum written by Amelia K. Linnemann and published by Frontiers Media SA. This book was released on 2022-02-11 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Advanced Optical Flow Cytometry by : Valery V. Tuchin
Download or read book Advanced Optical Flow Cytometry written by Valery V. Tuchin and published by John Wiley & Sons. This book was released on 2011-03-31 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed look at the latest research in non-invasive in vivo cytometry and its applications, with particular emphasis on novel biophotonic methods, disease diagnosis, and monitoring of disease treatment at single cell level in stationary and flow conditions. This book thus covers the spectrum ranging from fundamental interactions between light, cells, vascular tissue, and cell labeling particles, to strategies and opportunities for preclinical and clinical research. General topics include light scattering by cells, fast video microscopy, polarization, laser-scanning, fluorescence, Raman, multi-photon, photothermal, and photoacoustic methods for cellular diagnostics and monitoring of disease treatment in living organisms. Also presented are discussions of advanced methods and techniques of classical flow cytometry.
Book Synopsis Angiogenesis Assays by : Carolyn A. Staton
Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Book Synopsis Bridging the Gap in Neuroelectronic Interfaces by : Jeffrey R. Capadona
Download or read book Bridging the Gap in Neuroelectronic Interfaces written by Jeffrey R. Capadona and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Actin Cytoskeleton in Cancer Progression and Metastasis – Part C by :
Download or read book Actin Cytoskeleton in Cancer Progression and Metastasis – Part C written by and published by Academic Press. This book was released on 2021-05-04 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Actin Cytoskeleton in Cancer Progression and Metastasis - Part C, Volume 358 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. New chapters cover Actin isoforms in cancer, Actin cytoskeleton regulators at invadopodia, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and more. - Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology - Offers a wide range of perspectives for basic and translational research - Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications
Book Synopsis In Vivo Fluorescence Imaging by : Mingfeng Bai
Download or read book In Vivo Fluorescence Imaging written by Mingfeng Bai and published by Humana. This book was released on 2016-06-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume includes a rich variety of applications using various instrumentations, probes, disease models, and targets in order to account for the multidisciplinary nature of the use of in vivo fluorescence imagine. The book also includes chapters on the emerging fields of cell tracking, image-guided treatment, and fluorescence imaging in the second NIR window, as well as protocols for evaluation methods before and after in vivo imaging. Written for the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, In Vivo Fluorescence Imaging: Methods and Protocols serves as a valuable reference for researchers from numerous fields who wish to become more familiar with in vivo fluorescence imaging techniques.
Download or read book Advances in Applied Mechanics written by and published by Academic Press. This book was released on 2022-11-04 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Applied Mechanics, Volume 55 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Towards stochastic multi-scale methods in continuum solid mechanics, Fracture in soft elastic materials: Continuum description, molecular aspects and applications, Bio-Chemo-Mechanical Coupling Models of Soft Biological Materials: A Review, Viscoelasticity and cell swirling motion, Model selection and sensitivity analysis in the biomechanics of soft tissues: A case study on the human knee meniscus, Oncology and mechanics: Landmark studies and promising clinical. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Applied Mechanics series - Edited by some of the best scientists in the field
