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The Gene Machine
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Book Synopsis Gene Machine by : Venki Ramakrishnan
Download or read book Gene Machine written by Venki Ramakrishnan and published by Basic Books. This book was released on 2018-11-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.
Author :Bonnie Rochman Publisher :Scientific American / Farrar, Straus and Giroux ISBN 13 :0374713960 Total Pages :288 pages Book Rating :4.3/5 (747 download)
Book Synopsis The Gene Machine by : Bonnie Rochman
Download or read book The Gene Machine written by Bonnie Rochman and published by Scientific American / Farrar, Straus and Giroux. This book was released on 2017-02-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.
Book Synopsis The Selfish Gene by : Richard Dawkins
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Download or read book Murder Machine written by Gene Mustain and published by Penguin. This book was released on 1993-07-01 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The inside story of a single Brooklyn gang that killed more Americans than the Iraqi army."—Mike McAlary, columnist, New York Post They were the DeMeo gang—the most deadly hit men in organized crime. Their Mafia higher-ups came to know, use, and ultimately fear them as the Murder Machine. They killed for profit and for pleasure, following cold-blooded plans and wild whims, from the mean streets of New York to the Florida Gold Coast, and from coast to coast. Now complete with personal revelations of one of the key players, this is the savage story that leaves no corpse unturned in its terrifying telling. INCLUDES PHOTOGRAPHS
Book Synopsis The Meme Machine by : Susan Blackmore
Download or read book The Meme Machine written by Susan Blackmore and published by OUP Oxford. This book was released on 2000-03-16 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans are extraordinary creatures, with the unique ability among animals to imitate and so copy from one another ideas, habits, skills, behaviours, inventions, songs, and stories. These are all memes, a term first coined by Richard Dawkins in 1976 in his book The Selfish Gene. Memes, like genes, are replicators, and this enthralling book is an investigation of whether this link between genes and memes can lead to important discoveries about the nature of the inner self. Confronting the deepest questions about our inner selves, with all our emotions, memories, beliefs, and decisions, Susan Blackmore makes a compelling case for the theory that the inner self is merely an illusion created by the memes for the sake of replication.
Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Book Synopsis The Selfish Gene by : Richard Dawkins
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press. This book was released on 2016-05-26 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Download or read book Gene Machines written by Fran Balkwill and published by CSHL Press. This book was released on 2002 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summary: An introduction to how genes work, including basic information about cloning and gene therapy.
Book Synopsis The Exquisite Machine by : Sian E. Harding
Download or read book The Exquisite Machine written by Sian E. Harding and published by MIT Press. This book was released on 2024-02-06 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine. Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have not yet been able to replicate the heart’s perfect engineering. But, as Sian Harding shows us in The Exquisite Machine, new scientific developments are opening up the mysteries of the heart. And this explosion of new science—ultrafast imaging, gene editing, stem cells, artificial intelligence, and advanced sub-light microscopy—has crucial, real-world consequences for health and well-being. Harding—a world leader in cardiac research—explores the relation between the emotions and heart function, reporting that the heart not only responds to our emotions, it creates them as well. The condition known as Broken Heart Syndrome, for example, is a real disorder than can follow bereavement or stress. The Exquisite Machine describes the evolutionary forces that have shaped the heart’s response to damage, the astonishing rejuvenating power of stem cells, how we can avoid heart disease, and why it can be so hard to repair a damaged heart. It tells the stories of patients who have had the devastating experiences of a heart attack, chaotic heart rhythms, or stress-induced acute heart failure. And it describes how cutting-edge technologies are enabling experiments and clinical trials that will lead us to new solutions to the worldwide scourge of heart disease.
Book Synopsis Wilma Jean the Worry Machine by : Julia Cook
Download or read book Wilma Jean the Worry Machine written by Julia Cook and published by National Center for Youth Issues. This book was released on 2012-01-15 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: "My stomach feels like it's tied up in a knot. My knees lock up, and my face feels hot. You know what I mean? I'm Wilma Jean, The Worry Machine." Anxiety is a subjective sense of worry, apprehension, and/or fear. It is considered to be the number one health problem in America. Although quite common, anxiety disorders in children are often misdiagnosed and overlooked. Everyone feels fear, worry and apprehension from time to time, but when these feelings prevent a person from doing what he/she wants and/or needs to do, anxiety becomes a disability. This fun and humorous book addresses the problem of anxiety in a way that relates to children of all ages. It offers creative strategies for parents and teachers to use that can lessen the severity of anxiety. The goal of the book is to give children the tools needed to feel more in control of their anxiety. For those worries that are not in anyone's control (i.e. the weather) a worry hat is introduced. A fun read for Wilmas of all ages! Includes a note to parents and educators with tips on dealing with an anxious child.
Download or read book Junk DNA written by Nessa Carey and published by Icon Books. This book was released on 2015-03-05 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.
Book Synopsis Gene Expression Programming by : Candida Ferreira
Download or read book Gene Expression Programming written by Candida Ferreira and published by Springer. This book was released on 2006-08-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basic ideas of gene expression programming (GEP) and numerous modifications to this powerful new algorithm. It provides all the implementation details of GEP so that anyone with elementary programming skills will be able to implement it themselves. The book includes a self-contained introduction to this new exciting field of computational intelligence. This second edition has been revised and extended with five new chapters.
Book Synopsis Computational Genomics with R by : Altuna Akalin
Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
Book Synopsis DNA Is Not Destiny by : Steven J Heine
Download or read book DNA Is Not Destiny written by Steven J Heine and published by National Geographic Books. This book was released on 2018-08-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: “[An] important book.… Heine’s vibrant writing makes it come alive with personal significance for every reader.”—Carol Dweck, author of Mindset Scientists expect one billion people to have their genomes sequenced by 2025. Yet cultural psychologist Steven J. Heine argues that, in trying to know who we are and where we come from, we’re likely to completely misinterpret what’s “in our DNA.” Heine’s fresh, surprising conclusions about the promise, and limits, of genetic engineering and DNA testing upend conventional thinking and reveal a simple, profound truth: your genes create life—but they do not control it.
Download or read book The Immortal Gene written by Jonas Saul and published by . This book was released on 2018-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PLAYING GOD HAS CONSEQUENCES. Jake Wood has it made. He is a tough homicide detective with a partner who's like a brother, and he's about to marry the girl of his dreams. Then Jake learns a close friend is missing and travels to South America in search of him. After a freak accident in the Amazon Rainforest, Jake wakes up in the hospital--eighteen months later. Long presumed dead, he discovers his fiancée is married and pregnant, his house was sold, his job is gone, and his partner transferred to another city to become lead detective on a serial killer case. Jake buys a cabin in the woods and tries to leave the world behind, until his home is broken into and he discovers he was targeted--but why? When Jake's former partner requests his aid in catching the Blood Eagle Killer, he offers to help find whoever is behind Jake's recent trouble. This leads to Fortech Industries, a pharmaceutical company secretly researching a way to create an immortal gene. Now they intend to destroy their only error--Jake Wood--who has become something more than human.
Book Synopsis The Society of Genes by : Itai Yanai
Download or read book The Society of Genes written by Itai Yanai and published by Harvard University Press. This book was released on 2016-01-11 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since Dawkins popularized the notion of the selfish gene, the question of how these selfish genes work together to construct an organism remained a mystery. Now, standing atop a wealth of new research, Itai Yanai and Martin Lercher—pioneers in the field of systems biology—provide a vision of how genes cooperate and compete in the struggle for life.
Book Synopsis The Strangest Man by : Graham Farmelo
Download or read book The Strangest Man written by Graham Farmelo and published by Basic Books. This book was released on 2009-08-25 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul Dirac was among the great scientific geniuses of the modern age. One of the discoverers of quantum mechanics, the most revolutionary theory of the past century, his contributions had a unique insight, eloquence, clarity, and mathematical power. His prediction of antimatter was one of the greatest triumphs in the history of physics. One of Einstein’s most admired colleagues, Dirac was in 1933 the youngest theoretician ever to win the Nobel Prize in physics. Dirac’s personality is legendary. He was an extraordinarily reserved loner, relentlessly literal-minded and appeared to have no empathy with most people. Yet he was a family man and was intensely loyal to his friends. His tastes in the arts ranged from Beethoven to Cher, from Rembrandt to Mickey Mouse. Based on previously undiscovered archives, The Strangest Man reveals the many facets of Dirac’s brilliantly original mind. A compelling human story, The Strangest Man also depicts a spectacularly exciting era in scientific history.
