The Drug Crisis

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Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Medications for Opioid Use Disorder Save Lives

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309486483
Total Pages : 175 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Medications for Opioid Use Disorder Save Lives by : National Academies of Sciences, Engineering, and Medicine

Download or read book Medications for Opioid Use Disorder Save Lives written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-06-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Facing Addiction in America: the Surgeon General's Spotlight on Opioids

Author :
Publisher :
ISBN 13 :
Total Pages : 35 pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Facing Addiction in America: the Surgeon General's Spotlight on Opioids by :

Download or read book Facing Addiction in America: the Surgeon General's Spotlight on Opioids written by and published by . This book was released on 2018 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Overdose

Author : Chris McGreal
Publisher : PublicAffairs
ISBN 13 : 1541773772
Total Pages : 381 pages
Book Rating : 4.5/5 (417 download)

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Book Synopsis American Overdose by : Chris McGreal

Download or read book American Overdose written by Chris McGreal and published by PublicAffairs. This book was released on 2018-11-13 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

Death in Mud Lick

Author : Eric Eyre
Publisher : Simon and Schuster
ISBN 13 : 198210533X
Total Pages : 304 pages
Book Rating : 4.9/5 (821 download)

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Book Synopsis Death in Mud Lick by : Eric Eyre

Download or read book Death in Mud Lick written by Eric Eyre and published by Simon and Schuster. This book was released on 2020-03-31 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Critics’ Top Ten Book of the Year * 2021 Edgar Award Winner Best Fact Crime * A Lit Hub Best Book of The Year From a Pulitzer Prize–winning investigative reporter at the Charleston Gazette-Mail, a “powerful,” (The New York Times) urgent, and heartbreaking account of the corporate greed that pumped millions of pain pills into small Appalachian towns, decimating communities. In a pharmacy in Kermit, West Virginia, 12 million opioid pain pills were distributed in just three years to a town with a population of 382 people. One woman, after losing her brother to overdose, was desperate for justice. Debbie Preece’s fight for accountability for her brother’s death took her well beyond the Sav-Rite Pharmacy in coal country, ultimately leading to three of the biggest drug wholesalers in the country. She was joined by a crusading lawyer and by local journalist, Eric Eyre, who uncovered a massive opioid pill-dumping scandal that shook the foundation of America’s largest drug companies—and won him a Pulitzer Prize. Part Erin Brockovich, part Spotlight, Death in Mud Lick details the clandestine meetings with whistleblowers; a court fight to unseal filings that the drug distributors tried to keep hidden, a push to secure the DEA pill-shipment data, and the fallout after Eyre’s local paper, the Gazette-Mail, the smallest newspaper ever to win a Pulitzer Prize for investigative reporting, broke the story. Eyre follows the opioid shipments into individual counties, pharmacies, and homes in West Virginia and explains how thousands of Appalachians got hooked on prescription drugs—resulting in the highest overdose rates in the country. But despite the tragedy, there is also hope as citizens banded together to create positive change—and won. “A product of one reporter’s sustained outrage [and] a searing spotlight on the scope and human cost of corruption and negligence” (The Washington Post) Eric Eyre’s intimate portrayal of a national public health crisis illuminates the shocking pattern of corporate greed and its repercussions for the citizens of West Virginia—and the nation—to this day.

The Prescription Drug Problem

Author : Ryan D. Schroeder
Publisher : Bloomsbury Publishing USA
ISBN 13 :
Total Pages : 175 pages
Book Rating : 4.2/5 (161 download)

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Book Synopsis The Prescription Drug Problem by : Ryan D. Schroeder

Download or read book The Prescription Drug Problem written by Ryan D. Schroeder and published by Bloomsbury Publishing USA. This book was released on 2019-02-15 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an indispensable resource for undergraduate students, graduate students, and policymakers interested in the prescription drug abuse crisis in the United States, this book summarizes the current state of prescription drug abuse and its growth over the past 20 years. The Prescription Drug Problem analyzes the growth of the prescription drug abuse problem from 1994 to 2014 and includes comparisons to marijuana and hard drug use during the same period. Specific attention is given to prescription opiate abuse and the transition from prescription opiates to heroin. The book begins with a broad overview of the prescription drug problem in the U.S., while the text presents stories of celebrities who have struggled with prescription drug abuse, highlights a handful of ordinary Americans who are battling prescription drug abuse, and examines as case studies a few communities that have been ravaged by prescription drug abuse. Drawing upon demographic patterns of abuse to identify causes of and factors contributing to prescription drug abuse as well as possible solutions to the problem, the book is designed to provide a broad overview of the prescription drug abuse problem in the U.S. and stimulate additional research.

Dopesick

Author : Beth Macy
Publisher : Bloomsbury Publishing
ISBN 13 : 1788549368
Total Pages : 495 pages
Book Rating : 4.7/5 (885 download)

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Book Synopsis Dopesick by : Beth Macy

Download or read book Dopesick written by Beth Macy and published by Bloomsbury Publishing. This book was released on 2018-08-09 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now a major TV series on Disney+ 'A shocking investigation... Dopesick is essential' The Times 'Unfolds with all the pace of a thriller' Observer 'A deep – and deeply needed – look into the troubled soul of America' Tom Hanks 'Essential reading' New York Times Beth Macy reveals the disturbing truth behind America's opioid crisis and explains how a nation has become enslaved to prescription drugs. This powerful and moving story explains how a large corporation, Purdue, encouraged small town doctors to prescribe OxyContin to a country already awash in painkillers. The drug's dangerously addictive nature was hidden, whilst many used it as an escape, to numb the pain of of joblessness and the need to pay the bills. Macy tries to answer a grieving mother's question – why her only son died – and comes away with a harrowing tale of greed and need.

The Hard Sell

Author : Evan Hughes
Publisher : Doubleday
ISBN 13 : 038554491X
Total Pages : 227 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis The Hard Sell by : Evan Hughes

Download or read book The Hard Sell written by Evan Hughes and published by Doubleday. This book was released on 2022-01-18 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inside story of a band of entrepreneurial upstarts who made millions selling painkillers—until their scheme unraveled, putting them at the center of a landmark criminal trial. • SOON TO BE THE MAJOR MOTION PICTURE PAIN HUSTLERS STARRING EMILY BLUNT AND CHRIS EVANS "Unfolds with the velocity and verve of a Scorsese film…A tour de force."—Patrick Radden Keefe, New York Times bestselling author of Empire of Pain and Say Nothing John Kapoor had already amassed a small fortune in pharmaceuticals when he founded Insys Therapeutics. It was the early 2000s, a boom time for painkillers, and he developed a novel formulation of fentanyl, the most potent opioid on the market. Kapoor, a brilliant immigrant scientist with relentless business instincts, was eager to make the most of his innovation. He gathered around him an ambitious group of young lieutenants. His head of sales—an unstable and unmanageable leader, but a genius of persuasion—built a team willing to pull every lever to close a sale, going so far as to recruit an exotic dancer ready to scrape her way up. They zeroed in on the eccentric and suspect doctors receptive to their methods. Employees at headquarters did their part by deceiving insurance companies. The drug was a niche product, approved only for cancer patients in dire condition, but the company’s leadership pushed it more widely, and together they turned Insys into a Wall Street sensation. But several insiders reached their breaking point and blew the whistle. They sparked a sprawling investigation that would lead to a dramatic courtroom battle, breaking new ground in the government’s fight to hold the drug industry accountable in the spread of addictive opioids. In The Hard Sell, National Magazine Award–finalist Evan Hughes lays bare the pharma playbook. He draws on unprecedented access to insiders of the Insys saga, from top executives to foot soldiers, from the patients and staff of far-flung clinics to the Boston investigators who treated the case as a drug-trafficking conspiracy, flipping cooperators and closing in on the key players. With colorful characters and true suspense, The Hard Sell offers a bracing look not just at Insys, but at how opioids are sold at the point they first enter the national bloodstream—in the doctor’s office.

Pain Killer

Author : Barry Meier
Publisher : Rodale
ISBN 13 : 9781579546380
Total Pages : 348 pages
Book Rating : 4.5/5 (463 download)

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Book Synopsis Pain Killer by : Barry Meier

Download or read book Pain Killer written by Barry Meier and published by Rodale. This book was released on 2003-10-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines OxyContin, the so-called miracle prescription drug that swept the nation but led to overdoes and addiction, providing a look at the multi-billion-dollar pain managment business, its excesses and its abuses.

Dreamland (YA edition)

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
ISBN 13 : 1547601418
Total Pages : 225 pages
Book Rating : 4.5/5 (476 download)

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Book Synopsis Dreamland (YA edition) by : Sam Quinones

Download or read book Dreamland (YA edition) written by Sam Quinones and published by Bloomsbury Publishing USA. This book was released on 2019-07-16 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: As an adult book, Sam Quinones's Dreamland took the world by storm, winning the NBCC Award for General Nonfiction and hitting at least a dozen Best Book of the Year lists. Now, adapted for the first time for a young adult audience, this compelling reporting explains the roots of the current opiate crisis. In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital center of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America. How that happened is the riveting story of Dreamland. Quinones explains how the rise of the prescription drug OxyContin, a miraculous and extremely addictive painkiller pushed by pharmaceutical companies, paralleled the massive influx of black tar heroin--cheap, potent, and originating from one small county on Mexico's west coast, independent of any drug cartel. Introducing a memorable cast of characters--pharmaceutical pioneers, young Mexican entrepreneurs, narcotics investigators, survivors, teens, and parents--Dreamland is a revelatory account of the massive threat facing America and its heartland.

Fentanyl, Inc.

Author : Ben Westhoff
Publisher : Atlantic Monthly Press
ISBN 13 : 080214795X
Total Pages : 365 pages
Book Rating : 4.8/5 (21 download)

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Book Synopsis Fentanyl, Inc. by : Ben Westhoff

Download or read book Fentanyl, Inc. written by Ben Westhoff and published by Atlantic Monthly Press. This book was released on 2019-09-03 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: A four-year investigation into the world of synthetic drugs—from black market factories to users & dealers to harm reduction activists—and what it revealed. A deeply human story, Fentanyl, Inc. is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. “A whole new crop of chemicals is radically changing the recreational drug landscape,” writes Ben Westhoff. “These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs” —and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice—and those with arcane acronyms like 25i-NBOMe—were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs’ effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China’s vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the United States and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many. “Timely and agonizing. . . . An impressive work of investigative journalism.” —USA Today “Westhoff explores the many-tentacled world of illicit opioids, from the streets of East St. Louis to Chinese pharmaceutical companies, from music festivals deep in the Michigan woods to sanctioned ‘shooting up rooms’ in Barcelona, in this frank, insightful, and occasionally searing exposé. . . . Westhoff’s well-reported and researched work will likely open eyes, slow knee-jerk responses, and start much needed conversations.” —Publishers Weekly “Our 25 Favorite Books of 2019” —St. Louis Post-Dispatch “Best Books of 2019” —Buzzfeed “Best Nonfiction of 2019” —Kirkus Reviews “50 Best Books of 2019” —Daily Telegraph “Best Nonfiction Books of 2019” —Tyler Cowen “Best Books of 2019” —Yahoo Finance

Light Up the Night

Author : Travis Lupick
Publisher : The New Press
ISBN 13 : 1620976870
Total Pages : 286 pages
Book Rating : 4.6/5 (29 download)

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Book Synopsis Light Up the Night by : Travis Lupick

Download or read book Light Up the Night written by Travis Lupick and published by The New Press. This book was released on 2022-01-04 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revelatory, moving narrative that offers a harrowing critique of the war on drugs from voices seldom heard in the conversation: drug users who are working on the front lines to reduce overdose deaths Media coverage has established a clear narrative of the overdose crisis: In the 1990s, pharmaceutical corporations flooded America with powerful narcotics while lying about their risk; many patients developed addictions to prescription opioids; then, as access was restricted, waves of people turned to the streets and began using heroin and, later, the dangerous synthetic opioid fentanyl. But that’s not the whole story. It fails to acknowledge how the war on drugs has exacerbated the crisis and leaves out one crucial voice: that of drug users themselves. Across the country, people who use drugs are organizing in response to a record number of overdose deaths. They are banding together to save lives and demanding equal rights. Set against the backdrop of the overdose crisis, Light Up the Night provides an intimate look at how users navigate the policies that criminalize them. It chronicles a rising movement that’s fighting to save lives, end stigma, and inspire commonsense policy reform. Told through embedded reporting focused on two activists, Jess Tilley in Massachusetts and Louise Vincent in North Carolina, this is the story of the courageous people stepping in where government has failed. They are standing on the front lines of an underground effort to help people with addictions use drugs safely, reduce harms, and live with dignity.

The Least of Us

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
ISBN 13 : 1635578582
Total Pages : 433 pages
Book Rating : 4.6/5 (355 download)

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Book Synopsis The Least of Us by : Sam Quinones

Download or read book The Least of Us written by Sam Quinones and published by Bloomsbury Publishing USA. This book was released on 2021 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Warrior

Author : Jack Riley
Publisher : Hachette Books
ISBN 13 : 1602865841
Total Pages : 256 pages
Book Rating : 4.6/5 (28 download)

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Book Synopsis Drug Warrior by : Jack Riley

Download or read book Drug Warrior written by Jack Riley and published by Hachette Books. This book was released on 2019-02-19 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: DEA Agent Jack Riley, "[Chicago's] most famous federal agent since the days of The Untouchables" (-Rolling Stone) tells the inside story of his 30-year hunt for the drug kingpin known as El Chapo, and reveals the true causes of the American opioid epidemic. Jack Riley, grandson of a Chicago cop known for using his fists, was born to be a drug warrior. Joaquín "El Chapo" Guzmán Loera, who farmed marijuana and opium poppies as a teenager in Mexico, was born to be a drug lord. Their worlds collided when Riley, a career special agent with the Drug Enforcement Administration, was promoted to lead the fight against Chapo on the border at El Paso. Drug Warrior is the story of Riley's decades-long hunt for the world's most wanted drug lord, set against the rise of modern international drug trafficking, and America's spiraling opioid epidemic. Jack Riley started his career as an undercover street agent in Chicago busting small-time dealers. By the time he worked his way up to second in command of the DEA-a post few field agents ever reach-he had overseen every major mission to capture foreign drug kingpins since the 1990s, and had witnessed first-hand how El Chapo changed the game. As brilliant as he was lethal, Chapo not only decimated his competition, he foresaw Americans' dependence on opioids and heroin, and manipulated supply to increase demand. Riley's story culminates as he and the DEA win their greatest victory-the capture and extradition of his long-time nemesis-and Chapo faces his darkest fear: U.S. justice. A riveting memoir of life inside the drug wars, and a never-before-seen glimpse of the inner-workings of the DEA, Drug Warrior is a critical examination of how America's opioid crisis came to be, and the extraordinary people fighting it.

The Opioid Fix

Author : Barbara Andraka-Christou
Publisher : JHU Press
ISBN 13 : 142143766X
Total Pages : 289 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis The Opioid Fix by : Barbara Andraka-Christou

Download or read book The Opioid Fix written by Barbara Andraka-Christou and published by JHU Press. This book was released on 2020-04-21 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why medication-assisted treatment, the most effective tool for battling opioid addiction, is significantly underused in the United States. Bronze Winner of the 2021 IPPY Book Award in Health/Medicine/Nutrition, Gold Winner of the 2020 Foreword INDIES Award in Health America's addiction crisis is growing worse. More than 115 Americans die daily from opioid overdoses, with half a million deaths expected in the next decade. Time and again, scientific studies show that medications like Suboxone and methadone are the most reliable and effective treatment, yet more than 60 percent of US addiction treatment centers fail to provide access to them. In The Opioid Fix, Barbara Andraka-Christou highlights both the promise and the underuse of medication-assisted treatment (MAT). Addiction, Andraka-Christou writes, is a chronic medical condition. Why treat it, then, outside of mainstream medicine? Drawing on more than 100 in-depth interviews with people in recovery, their family members, treatment providers, and policy makers, Andraka-Christou reveals a troubling landscape characterized by underregulated treatment centers and unnecessary ideological battles between twelve-step support groups and medication providers. The resistance to MAT—from physicians who won't prescribe it, to drug courts that prohibit it, to politicians who overregulate it—showcases the narrow-mindedness of the system and why it isn't working. Recounting the true stories of people in recovery, this groundbreaking book argues that MAT needs to be available to anyone suffering from opioid addiction. Unlike other books about the opioid crisis, which have largely focused on causal factors like pharmaceutical overprescription and heroin trafficking, this book focuses on people who have already developed an opioid addiction but are struggling to find effective treatment. Validating the experience of hundreds of thousands of Americans, The Opioid Fix sounds a loud call for policy reforms that will help put lifesaving drugs into the hands of those who need them the most.

American Fix

Author : Ryan Hampton
Publisher : Macmillan + ORM
ISBN 13 : 1250196272
Total Pages : 295 pages
Book Rating : 4.2/5 (51 download)

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Book Synopsis American Fix by : Ryan Hampton

Download or read book American Fix written by Ryan Hampton and published by Macmillan + ORM. This book was released on 2018-08-28 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly every American knows someone who has been affected by the opioid crisis. Addiction is a trans-partisan issue that impacts individuals from every walk of life. Millions of Americans, tired of watching their loved ones die while politicians ignore this issue. Where is the solution? Where is the hope? Where's the outrage? Ryan Hampton is a young man who has made addiction and recovery reform his life's mission. Through the wildly successful non-profit organization Facing Addiction, Hampton has been rocketed to the center of America’s rising recovery movement—quickly emerging as the de facto leader of the national conversation on addiction. He understands firsthand how easy it is to develop a dependency on opioids, and how destructive it can quickly become. Now, he is waging a permanent campaign to change our way of thinking about and addressing addiction in this country. In American Fix, Hampton describes his personal struggle with addiction, outlines the challenges that the recovery movement currently faces, and offers a concrete, comprehensive plan of action towards making America’s addiction crisis a thing of the past.

Empire of Pain

Author : Patrick Radden Keefe
Publisher : Anchor
ISBN 13 : 038554569X
Total Pages : 574 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis Empire of Pain by : Patrick Radden Keefe

Download or read book Empire of Pain written by Patrick Radden Keefe and published by Anchor. This book was released on 2021-04-13 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing. "A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. It follows the family’s early success with Valium to the much more potent OxyContin, marketed with a ruthless technique of co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. A masterpiece of narrative reporting, Empire of Pain is a ferociously compelling portrait of America’s second Gilded Age, a study of impunity among the super-elite and a relentless investigation of the naked greed that built one of the world’s great fortunes.