Chelation Therapy in the Treatment of Metal Intoxication

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Author :
Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Chelation Therapy in the Treatment of Metal Intoxication by : Jan Aaseth

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). Presents all the current findings on the potential for chelation as a therapy for metal intoxication Presents practical guidelines for selecting the most appropriate chelating agent Includes coverage on radionuclide exposure and metal storage diseases Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Metal Chelation in Medicine

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782623892
Total Pages : 336 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Metal Chelation in Medicine by : Robert R Crichton

Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Hepatotoxicity

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Heavy Metal Pollution, Toxication and Chelation

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Author :
Publisher : M.D. Publications Pvt. Ltd.
ISBN 13 : 9788175330764
Total Pages : 422 pages
Book Rating : 4.3/5 (37 download)

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Book Synopsis Heavy Metal Pollution, Toxication and Chelation by : Ram Prakash

Download or read book Heavy Metal Pollution, Toxication and Chelation written by Ram Prakash and published by M.D. Publications Pvt. Ltd.. This book was released on 1998 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has up-to-date literature and research findings on the heavy metals such as, mercury, cobalt, cadmium, managnese, copper, chromium, boron, iron, lead, nickel, selenium, vanadium, zinc, arsenic, silver, gold, etc. The author have discussed their histopathological, biochemical, histochemical and enzymological effects in plants and animals, particularly in liver, kidney, heart, muscles, brain, bones, reproductive organs, intestine, endocrine system, etc.

The Chelation Controversy

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Author :
Publisher : Basic Health Publications, Inc.
ISBN 13 : 9781591200567
Total Pages : 68 pages
Book Rating : 4.2/5 (5 download)

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Book Synopsis The Chelation Controversy by : Gregory Pouls

Download or read book The Chelation Controversy written by Gregory Pouls and published by Basic Health Publications, Inc.. This book was released on 2005 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safely Rid Your Body of Stored Chemicals and Heavy Metals If you live in this modern world of ours, your body is being exposed to oxidizing chemicals and heavy metals such as aluminum, arsenic, cadmium, and lead on a daily basis. When your body starts accumulating toxins faster than it can eliminate them, it begins to store them in your tissues. These stored toxins initiate degenerative processes in your body that can lead to diseases such as cancer, heart disease, and arthritis. Chelating agents--substances that latch on to and carry toxins out of the body--can help you free yourself of this destructive load. In The Chelation Controversy, Drs. Gregory and Maile Pouls discuss the use of chelating agents, including those taken orally and those given intravenously. The authors also familiarize you with some of the controversy surrounding chelation therapy. In addition to a comprehensive guide to the "big six" heavy metals and a discussion on the harmful effects of oxidation, the authors cover the most common prescription IV and oral chelating agents. They also provide guidance on what to look for in an oral chelation formula and describe the nutritional substances and antioxidants that can support your detoxification efforts. If your exposure to toxins is higher than average or if you simply want to preserve, maintain, support, and enhance your health, energy, and vitality in this toxic world, The Chelation Controversy provides the information you need to put this therapy to work for you.

Evidence-Based Clinical Chelation

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 3750428670
Total Pages : 122 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Evidence-Based Clinical Chelation by : Dr. Eleonore Blaurock-Busch, PhD

Download or read book Evidence-Based Clinical Chelation written by Dr. Eleonore Blaurock-Busch, PhD and published by BoD – Books on Demand. This book was released on 2020-06-02 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an easy-to-read manual about chelation therapy. It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the inexperienced and the experienced therapist in selecting the optimal chelating agent for the metal(s) in question. Expert chemists and chelation therapists have contributed invaluable knowledge and experience to this book. Most importantly, this is not a book promoting personal views or preferences. In fact, the information presents and explains different approaches, and allows the reader to draw his own conclusion. All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous treatment plans. The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the detoxification of certain organ system. Also discussed is the importance and effect of treatment pauses. Diagnostic tests are discussed, and which are useful under certain conditions. Shown are tables comparing the average metal binding ability of the various EDTAs, DMPS, DMSA and other chelating agents. Detailed information explains which chelator binds which metal and why, all of which aids the therapist in finding optimal treatment schedules. Novel chelating agents are presented such as MIADMSA, a new oral chelator specifically designed for arsenic intoxication, or how natural Pectin may be used an alternative for gadolinium intoxication, which metals are bound by lipoic acid and why a slightly alkaline environment supports metal binding, even preventing the often-feared metal redistribution. All in all, this evidence-based chelation "cookbook" should be in medical libraries and on the bookshelf of every physician treating environmental disease.

Zinc Signaling

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Author :
Publisher : Springer Nature
ISBN 13 : 9811505578
Total Pages : 412 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Zinc Signaling by : Toshiyuki Fukada

Download or read book Zinc Signaling written by Toshiyuki Fukada and published by Springer Nature. This book was released on 2019-12-13 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.

Iron Chelation Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461505933
Total Pages : 275 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Iron Chelation Therapy by : Chaim Hershko

Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Detox with Oral Chelation

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Author :
Publisher :
ISBN 13 : 9781890572204
Total Pages : 0 pages
Book Rating : 4.5/5 (722 download)

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Book Synopsis Detox with Oral Chelation by : David Jay Brown

Download or read book Detox with Oral Chelation written by David Jay Brown and published by . This book was released on 2007-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: EDTA chelation therapy has been shown to improve blood circulation, lower blood pressure, and remove toxic heavy metals from the body. In a day and age where astonishing new advances in medicine are made almost daily, and our vision of the future of medicine borders on the miraculous, this overlooked, inexpensive, and often misunderstood form of therapy offers us the hope that we can all live longer, healthier, and happier lives right now.

Amalgam Illness

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Author :
Publisher : Andrew Cutler
ISBN 13 : 9780967616803
Total Pages : 240 pages
Book Rating : 4.6/5 (168 download)

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Book Synopsis Amalgam Illness by : Andrew Hall Cutler

Download or read book Amalgam Illness written by Andrew Hall Cutler and published by Andrew Cutler. This book was released on 1999 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chelation Therapy

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Author :
Publisher : Independently Published
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.3/5 (329 download)

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Book Synopsis Chelation Therapy by : Sharon G Brown

Download or read book Chelation Therapy written by Sharon G Brown and published by Independently Published. This book was released on 2024-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revolutionizing Health through Heavy Metal Removal Imagine a treatment that can rid your body of dangerous heavy metals, enhance heart health, and even provide relief for chronic ailments. This is not science fiction; it is the promise of chelation therapy, a medical procedure based on detoxification and rejuvenation. Chelation therapy involves administering chelating agents, which are chemicals that bind to heavy metals and minerals in the body allowing them to be eliminated. Chelation therapy, which was first created to treat heavy metal poisoning, has now evolved to treat a wide range of health concerns, such as atherosclerosis, neurological illnesses (autism spectrum disorders, brain tumors, cerebral palsy and ADD, ), and cardiovascular disease. This guide will provide you with the following: A thorough examination of the history, mechanisms of chelation therapy Several approaches to chelation, such as EDTA, DMSA and natural chelators. Detailed protocols that demonstrate the practical implementation of chelation therapy. Potential advantages, hazards, and the most recent scientific discoveries that substantiate the effectiveness of chelation therapy. The significance of tailored treatment regimens and the influence of diet and lifestyle in optimizing the advantages of detoxification. Whether you are a healthcare practitioner, a patient seeking alternative treatments, or simply inquisitive about the latest medical developments, this book offers useful insights and practical guidance on incorporating chelation therapy into a comprehensive health plan. Acquire the necessary knowledge to make well-informed decisions regarding your health and explore the potential of obtaining optimal well-being via the strategic application of chelation therapy.

Toxic Metal Syndrome

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Publisher : Penguin
ISBN 13 : 9780895296498
Total Pages : 436 pages
Book Rating : 4.2/5 (964 download)

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Book Synopsis Toxic Metal Syndrome by : Herman Richard Casdorph

Download or read book Toxic Metal Syndrome written by Herman Richard Casdorph and published by Penguin. This book was released on 1995 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Toxic Metal Syndrome" exposes the root causes of the wastes that cause debilitating conditions and pollute the environment and explodes the myth that nothing can be done to avoid or treat them.

The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine

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Publisher : Springer
ISBN 13 : 9811053111
Total Pages : 394 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine by : Richard Eugene Frye

Download or read book The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine written by Richard Eugene Frye and published by Springer. This book was released on 2018-09-20 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

Heavy Metal Stress in Plants

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Publisher : Springer Science & Business Media
ISBN 13 : 3662077450
Total Pages : 405 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Heavy Metal Stress in Plants by : M.N.V. Prasad

Download or read book Heavy Metal Stress in Plants written by M.N.V. Prasad and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heavy metal phytotoxicity has been known for more than a century. However, research in the past years has confirmed the immense damage by metal pollution to plants, the soil and ultimately to humans. By reviewing both field and laboratory work, this book deals with the various functional and ecological aspects of heavy metal stress on plants and outlines the scope for future research and the possibilities for remediation.

Poisoning in the Modern World

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Publisher : BoD – Books on Demand
ISBN 13 : 1838807853
Total Pages : 130 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Poisoning in the Modern World by : Ozgur Karcioglu

Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Chelating Agents and Metal Chelates

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Author :
Publisher : Elsevier
ISBN 13 : 0323146414
Total Pages : 547 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Chelating Agents and Metal Chelates by : F Dwyer

Download or read book Chelating Agents and Metal Chelates written by F Dwyer and published by Elsevier. This book was released on 2012-12-02 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelating Agents and Metal Chelates focuses on the structure and properties of metal chelates, as well as bond types, stereochemistry, and optical phenomena. The selection first offers information on historical background and fundamental concepts and the nature of metal-ligand bond. Discussions focus on the structure and stability of metal chelates, bond types and characteristic properties, classes of acceptor metal atoms, and metal-metal bonds in complex compounds. The text also touches on bidentate chelates, design and stereochemistry of multidentate chelating agents, and optical phenomena in metal chelates. The publication ponders on oxidation-reduction potentials as functions of donor atom and ligand and metal chelates of ethylenediaminetetraacetic acid and related substances. Topics include liquid junction potentials, reversibility, measurement of redox potentials, ethylenediaminetetraacetato chelate couples, and metal chelates of ethylenediaminetetraacetic acid. The text also takes a look at metal chelates in biological systems and physical and coordination chemistry of tetrapyrrole pigments. The manuscript is a vital reference for senior students, research workers, biologists, and medical scientists interested in the chemistry of metal chelates.

The Chelation Revolution

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Author :
Publisher : Humanix Books
ISBN 13 : 1630061204
Total Pages : 175 pages
Book Rating : 4.6/5 (3 download)

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Book Synopsis The Chelation Revolution by : Gary Greenberg

Download or read book The Chelation Revolution written by Gary Greenberg and published by Humanix Books. This book was released on 2020-08-04 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Medical Breakthrough of Chelation Therapy: A treatment that uses medicine to remove toxic metals from the body so they don't make you sick. Chelation has long been approved by the FDA to rid the body of lead by using a synthetic amino acid (ethylene diamine tetraacetic acid), which binds to toxic metals and minerals in the bloodstream, allowing a patient to excrete them. When metals like lead, mercury, iron, and arsenic build up in your body, they can be toxic. Alternative medical practitioners have used chelation for nearly 60 years, especially to treat heavy metal contamination that causes or contributes to heart disease. Chelation rids the body of deposits that can lead to atherosclerosis, which causes coronary arteries to narrow, leading to heart attacks. Patients have also found relief through chelation for improving the symptoms of autism. One of the most promising areas of research is in the treatment of Alzheimer’s disease. Because the buildup of metals like copper, iron, and zinc are thought to play a role in Alzheimer's disease, Chelation Therapy might have a place in treating it. Full of hope-inspiring case histories, expert findings and where to find treatment, The Chelation Revolution: Breakthrough Detox Therapy shows how Chelation Therapy can alleviate suffering in numerous medical conditions and lead to a healthier, happier, and longer life. Includes a Foreword by Tammy Born Huizenga, D.O., owner of the internationally recognized Born Clinic in Grand Rapids, MI, an internationally respected organization in preventive medicine with a speciality in Chelation Therapy.