The Biology And Therapeutic Application Of Mesenchymal Cells 2 Volume Set

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The Biology and Therapeutic Application of Mesenchymal Cells, 2 Volume Set

Author : Kerry Atkinson
Publisher : John Wiley & Sons
ISBN 13 : 1118907515
Total Pages : 1080 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis The Biology and Therapeutic Application of Mesenchymal Cells, 2 Volume Set by : Kerry Atkinson

Download or read book The Biology and Therapeutic Application of Mesenchymal Cells, 2 Volume Set written by Kerry Atkinson and published by John Wiley & Sons. This book was released on 2017-01-17 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues Written and edited by leaders in the field The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine.

The Biology and Therapeutic Application of Mesenchymal Cells

Author : Kerry Atkinson
Publisher :
ISBN 13 : 9781118907818
Total Pages : 967 pages
Book Rating : 4.9/5 (78 download)

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Book Synopsis The Biology and Therapeutic Application of Mesenchymal Cells by : Kerry Atkinson

Download or read book The Biology and Therapeutic Application of Mesenchymal Cells written by Kerry Atkinson and published by . This book was released on 2017 with total page 967 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Mesenchymal Stromal Cells

Author : Peiman Hematti
Publisher : Springer Science & Business Media
ISBN 13 : 1461457114
Total Pages : 697 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Mesenchymal Stromal Cells by : Peiman Hematti

Download or read book Mesenchymal Stromal Cells written by Peiman Hematti and published by Springer Science & Business Media. This book was released on 2013-01-16 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells. However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs. This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs. Features include: Coverage of the biology of MSCs, latest understanding of mechanisms of action, and role in tissue homeostasis and regeneration Identifying the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues.

Mesenchymal Stem Cells in Human Health and Diseases

Author : Ahmed El-Hashash
Publisher : Academic Press
ISBN 13 : 0128205334
Total Pages : 230 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Mesenchymal Stem Cells in Human Health and Diseases by : Ahmed El-Hashash

Download or read book Mesenchymal Stem Cells in Human Health and Diseases written by Ahmed El-Hashash and published by Academic Press. This book was released on 2020-01-07 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Stem Cells: Current Challenges and New Directions

Author : Kursad Turksen
Publisher : Springer Science & Business Media
ISBN 13 : 1461480663
Total Pages : 379 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Stem Cells: Current Challenges and New Directions by : Kursad Turksen

Download or read book Stem Cells: Current Challenges and New Directions written by Kursad Turksen and published by Springer Science & Business Media. This book was released on 2013-09-24 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume looks at the state-of-the-science in stem cells, discusses the current challenges, and examines the new directions the field is taking. Dr. Turksen, editor-in-chief of the journal "Stem Cell Reviews and Reports," has assembled a volume of internationally-known scientists who cover topics that are both clinically and research-oriented. The contents range from sources of stem cells through their physiological role in health and disease, therapeutic applications in regenerative medicine, and ethics and society. An initial overview and a final summary bookend the contents into a cohesive and invaluable volume.

Mesenchymal Stem Cells

Author : Darwin J. Prockop
Publisher : Humana Press
ISBN 13 : 9781588297716
Total Pages : 0 pages
Book Rating : 4.2/5 (977 download)

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Book Synopsis Mesenchymal Stem Cells by : Darwin J. Prockop

Download or read book Mesenchymal Stem Cells written by Darwin J. Prockop and published by Humana Press. This book was released on 2008-03-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Cutting edge and easy to use, this book is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.

Mesenchymal Stem Cell Assays and Applications

Author : Mohan C Vemuri
Publisher : Humana Press
ISBN 13 : 9781493957798
Total Pages : 534 pages
Book Rating : 4.9/5 (577 download)

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Book Synopsis Mesenchymal Stem Cell Assays and Applications by : Mohan C Vemuri

Download or read book Mesenchymal Stem Cell Assays and Applications written by Mohan C Vemuri and published by Humana Press. This book was released on 2017-05-04 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal Stem Cells have seen an unprecedented level of interest in the last decade, primarily due to their relative ease of isolation, the large numbers of cells present in the adult, and the ability to propagate these cells in culture. In Mesenchymal Stem Cell Assays and Applications, expert researchers from across the globe explore the latest techniques to propagate, characterize, and engineer this special cell type. Chapters outline a set of protocols and assays used by leading investigators in the field, providing standards that can be applied by all researchers to the population of cells used in their experiments. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Ground-breaking and current, Mesenchymal Stem Cell Assays and Applications is a necessary handbook for all researchers working with this ambiguous population of cells.

Principles of Stem Cell Biology and Cancer

Author : Tarik Regad
Publisher : John Wiley & Sons
ISBN 13 : 1118670620
Total Pages : 378 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Principles of Stem Cell Biology and Cancer by : Tarik Regad

Download or read book Principles of Stem Cell Biology and Cancer written by Tarik Regad and published by John Wiley & Sons. This book was released on 2015-05-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

Principles of Regenerative Medicine

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0123814235
Total Pages : 1203 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Mesenchymal Stem Cell in Veterinary Sciences

Author : Mudasir Bashir Gugjoo
Publisher : Springer Nature
ISBN 13 : 9811560374
Total Pages : 347 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Mesenchymal Stem Cell in Veterinary Sciences by : Mudasir Bashir Gugjoo

Download or read book Mesenchymal Stem Cell in Veterinary Sciences written by Mudasir Bashir Gugjoo and published by Springer Nature. This book was released on 2020-11-09 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications. After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs. Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.

Perinatal Stem Cells

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0128120630
Total Pages : 418 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Perinatal Stem Cells by : Anthony Atala

Download or read book Perinatal Stem Cells written by Anthony Atala and published by Academic Press. This book was released on 2018-06-14 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells

Tissue Barriers in Disease, Injury and Regeneration

Author : Nikolai V. Gorbunov
Publisher : Elsevier
ISBN 13 : 0128227567
Total Pages : 208 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Tissue Barriers in Disease, Injury and Regeneration by : Nikolai V. Gorbunov

Download or read book Tissue Barriers in Disease, Injury and Regeneration written by Nikolai V. Gorbunov and published by Elsevier. This book was released on 2021-06-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Barriers in Disease, Injury and Regeneration focuses on the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers, covering the damaging impacts and exposure to pathogens and engineered nanomaterials. Sections emphasize the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells, along with reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and metabolic status. Other sections cover the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and more. Includes special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid and reticuloendothelial cells in the development of reactions that bridge the effects of ambient factors, medical treatments, drag delivery systems with alterations in barrier integrity, tissue/organ functions, and in metabolic status Examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and mucosa and external epithelium

Tissue Engineering and Regenerative Medicine

Author : Phuc Van Pham
Publisher : Springer
ISBN 13 : 303019857X
Total Pages : 225 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Tissue Engineering and Regenerative Medicine by : Phuc Van Pham

Download or read book Tissue Engineering and Regenerative Medicine written by Phuc Van Pham and published by Springer. This book was released on 2019-08-14 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Tissue Engineering and Regenerative Medicine is a proceedings volume which reflects papers presented at the 3rd bi-annual Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Stem Cells: Biology and Engineering it provides a complete overview of the papers from that meeting of international experts.

Stromal Cells

Author : Mani T. Valarmathi
Publisher : BoD – Books on Demand
ISBN 13 : 1789849845
Total Pages : 262 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Stromal Cells by : Mani T. Valarmathi

Download or read book Stromal Cells written by Mani T. Valarmathi and published by BoD – Books on Demand. This book was released on 2019-01-23 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and interactions in physiological (epithelial-stromal interactions) as well as pathophysiological (stromal-cancer interactions) contexts. In addition, stromal cells are also utilized more and more as a therapeutic tool not only in the field of gene therapy but also in the translational field of tissue engineering and regenerative medicine. Therefore, the goal of this book is to consolidate the recent advances in the area of stromal/stromal stem cell biology covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough overview of stromal cell structure, function, and its therapeutic implications.

Concepts and Applications of Stem Cell Biology

Author : Gabriela Rodrigues
Publisher : Springer Nature
ISBN 13 : 3030439399
Total Pages : 267 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Concepts and Applications of Stem Cell Biology by : Gabriela Rodrigues

Download or read book Concepts and Applications of Stem Cell Biology written by Gabriela Rodrigues and published by Springer Nature. This book was released on 2020-06-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook will support graduate students with learning materials rich in the basic concepts of stem cell biology, in its most widespread and updated perspective. The chapters are conceived in a way for students to understand the meaning of pluripotency, the definition of embryonic stem cells and the formation of multicellular structures such as organoids together with the underlying principles of their epigenetic. This textbook also discusses adult stem cells and the potential use of these cells, in particular neural, mesenchymal, and several types of muscular cells, in biomedical research and clinical applications. This textbook represents a vital complement to the text on Essential Current Concepts of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Mesenchymal Stem Cell Derived Exosomes

Author : Yaoliang Tang
Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 287 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies