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The Biogenesis Of Cellular Organelles
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Book Synopsis The Biogenesis of Cellular Organelles by : Chris Mullins
Download or read book The Biogenesis of Cellular Organelles written by Chris Mullins and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the endoplasmic reticulum, Golgi, lysosome, nucleus, mitochondria, and peroxisome.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cell Organelles by : Reinhold G. Herrmann
Download or read book Cell Organelles written by Reinhold G. Herrmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The compartmentation of genetic information is a fundamental feature of the eukaryotic cell. The metabolic capacity of a eukaryotic (plant) cell and the steps leading to it are overwhelmingly an endeavour of a joint genetic cooperation between nucleus/cytosol, plastids, and mitochondria. Alter ation of the genetic material in anyone of these compartments or exchange of organelles between species can seriously affect harmoniously balanced growth of an organism. Although the biological significance of this genetic design has been vividly evident since the discovery of non-Mendelian inheritance by Baur and Correns at the beginning of this century, and became indisputable in principle after Renner's work on interspecific nuclear/plastid hybrids (summarized in his classical article in 1934), studies on the genetics of organelles have long suffered from the lack of respectabil ity. Non-Mendelian inheritance was considered a research sideline~ifnot a freak~by most geneticists, which becomes evident when one consults common textbooks. For instance, these have usually impeccable accounts of photosynthetic and respiratory energy conversion in chloroplasts and mitochondria, of metabolism and global circulation of the biological key elements C, N, and S, as well as of the organization, maintenance, and function of nuclear genetic information. In contrast, the heredity and molecular biology of organelles are generally treated as an adjunct, and neither goes as far as to describe the impact of the integrated genetic system.
Book Synopsis Biochemistry and Structure of Cell Organelles by : Robert A. Reid
Download or read book Biochemistry and Structure of Cell Organelles written by Robert A. Reid and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: THIS BOOK HAS BEEN WRITTEN BECAUSE WE FEEL THAT THERE IS A NEED FOR AN up-to-date compact book on cell organelles that transmits the excitement and challenge of modern subcellular biology. We hope that the book will be interesting and useful to students of the biological sciences and medicine, and to those in the teaching professions who do not have ready access to research papers. Since space is at a premium, we have denied ourselves the luxury of a philosophical discussion of the problems of defining organelles. Rather we have chosen to include all those intracellular structures which have limiting membranes and definable compartments. The separate chapters consider nuclei, plastids, mitochondria, microbodies, endoplasmic and sarcoplasmic reticulum; Golgi bodies, lysosomes and various secretory vesicles, including chromaffin granules and synaptic vesicles. Nucleoli, ribosomes, and centrioles are included in the chapter on nuclei. New and exciting informatioIi about all these structures has emerged in recent years-for example; the nUcleosome, interrupted genes, signal sequences on proteins destined. for the bioenergetic organelles, mapping and sequencing of organelle genes, and consolidation of chemiosmosis as a unifying principle in energy transduction. We have outlined as many of these developments as possible and pointed out some areas of controversy. The literature on subcellular biology is so extensive that it would have been easier to have written a separate book on each organelle.
Book Synopsis Cells and Organelles by : Alex Benjamin Novikoff
Download or read book Cells and Organelles written by Alex Benjamin Novikoff and published by . This book was released on 1970 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of the diverse facts of modern cytology & cell biology.
Book Synopsis Formation and Fate of Cell Organelles by : Katherine Brehme Warren
Download or read book Formation and Fate of Cell Organelles written by Katherine Brehme Warren and published by Elsevier. This book was released on 2012-12-02 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formation and Fate of Cell Organelles presents the proceedings of the symposia of the International Society for Cell Biology. Contributors offer their views on various aspects of the problem of spontaneous assembly, particularly how cellular structures arise from the component molecules. They consider whether all cellular organelles and cells, themselves, can arise by spontaneous assembly, or whether some regulation is involved and the mechanisms underlying such regulation. This book is organized into 16 chapters and begins with an overview of self-assembling systems of equal units and how they can be built efficiently, focusing on quasi-equivalence and helical waves on bacterial flagella. This text also discusses the differences in free energy of the molecules in their various states and the use of the free energy of a particular array of molecules to predict what arrays will form. The reader is introduced to intermolecular forces and how macromolecular lipid structures assemble in vitro, along with developments in the resolution of the spindle fibers of the mitotic apparatus. The book also looks into the mechanisms underlying the disposition of microtubules in plant cells during interphase and mitosis, and then concludes with a chapter on some studies dealing with cytoplasmic genes and cytoplasmic inheritance. This book is a valuable source of information for scientists and researchers engaged in fields ranging from cytology and biology to chemistry, pathology, and biophysics.
Book Synopsis Cellular Organelles and the Extracellular Matrix by : Edward Bittar
Download or read book Cellular Organelles and the Extracellular Matrix written by Edward Bittar and published by Elsevier. This book was released on 1996-01-04 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is in two parts. The first contains the remaining chapters on cellular organelles and several chapters relating to organelle disorders. An account of mitochondriopathis is given in the chapter on the mitochondrion rather than in a separate one. The subject matter of this part of the volume shows quite clearly that the interdisciplinary approach to the study of organelles has shed considerable light on the nature of the mechanisms underlying the etiology and pathobiology of many of these disorders. As an example, mutations in the genes encoding integral membrane proteins are found to lead to disturbances in peroxisome assembly. It is also interesting and significant that mistargeting of protein is now thought to be another cause. It will be revealing to see whether mistargeting is the result of mutations in the genes encoding chaperones. The second part of the volume is concerned with the extracellular matrix. It sets out to show that a vast body of new knowledge of the extracellular matrix is available to us. Take for example the integrin family of cell adhesion receptors. It turns out that integrins play a key role not only in adhesion but also in coupling signals to the nucleus via the cytoskeleton. As for fibronectins, they seem to link the matrix with the cytoskeleton by interacting with integrins. Collagen molecules are dealt with in the last two chapters. The boundaries of collagen in disease are defined by drawing a clear line of demarcation between systemic connective tissue disorders (e.g., scleroderma), better known as autoimmune diseases, and the heritable, and the heritable diseases such as osteogenesis imperfect and the Marfan syndrome. This classification takes into account a second group of acquired disorders of collagen forming tissues in which regional fibrosis is the hallmark. Liver cirrhosis and pulmonary fibrosis are prime examples. The decision to place Volumes 2 and 3 before those dealing with cell chemistry was not easily made. It was based on the view that most students will have had an undergraduate course in biochemistry of cell biology or both courses, and that they could go to Volumes 4-7 in which the subject of cell chemistry is covered, and then return to Volumes 2 and 3.
Book Synopsis Membrane Biogenesis by : Doron Rapaport
Download or read book Membrane Biogenesis written by Doron Rapaport and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane proteins and membrane lipids form complex interactive systems that are highly dynamic and able to be studied only by combinations of different in vivo and in vitro techniques. In Membrane Biogenesis: Methods and Protocols, experts in the field present a broad collection of methods to study the biogenesis and function of cellular membranes. Beginning with how membrane lipids or membrane proteins can be studied, this detailed volume continues with sections covering different procedures to investigate the interaction of membrane proteins among each other or with membrane lipids, methods to study the biogenesis of membrane proteins and the dynamics of organelles, as well as protocols for the analyses of the functions or complex organization of membrane proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Extensive and easily applicable, Membrane Biogenesis: Methods and Protocols provides readers with a comprehensive but still concise collection including both basic protocols of rather general application and more specialized methods for specific and novel techniques.
Book Synopsis Membrane Biogenesis by : Jos A.F. Op den Kamp
Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.
Book Synopsis Origin and Continuity of Cell Organelles by : J. Reinert
Download or read book Origin and Continuity of Cell Organelles written by J. Reinert and published by Springer. This book was released on 2014-04-18 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of the series, on "The Stability of the Differentiated State" received many favorable reviews from the scientific community. Many readers seem to agree with us that publication of topical volumes is a worthwhile alternative to periodic compilations of rather unrelated, though up-to-date reviews. Production of topical volumes is however, plagued with one great difficulty, that of "author synchronization". This difficulty explains the lag between volumes 1 and 2 of the series. Nevertheless we hope that the present volume will be appreciated as a valuable source of information on its central topic: How do cell organelles originate, and what mechanisms assure their continuity? Tübingen, Berlin, Zürich, \V. BEERMANN, J. REINERT, H. URSPRUNG, Heidelberg H. -W. HA GENS Contents Assembly, Continuity, and Exchanges in Certain Cytoplasmic Membrane Systems by W. GORDON WHALEY, MARIANNE DAUWALDER, aüd ]OYCE E. KEPHART 1 I. The Nature of the Membrane. . . . . . H. The Assembly of Membranes . . . . . . 5 III. The Growth and Transfer of Membranes. 6 A. The Nuclear Envelopc . . . 6 B. The Endoplasmic Reticulum 13 C. The Golgi Apparatus . 17 D. The Plasma Membrane 28 E. Vacuoles and Vesicles 31 IV. Concluding Remarks 37 References . . . . . 38 Origin and Continuity of Mitochondria by ROBERT BAXTER 1. Introduction . . . . . . . . . . . . . 46 H. Mitochondrial Biogenesis : thc Machincry 46 III. Limitations of Mitochondrial Autonomy 50 IV. The Replication of Mitochondria 53 V. Discussion and Conclusion 58 Referenccs . . . . . . . . . 59 Origin and Continuity of Plastids by \VILFRIED STUBBE 1. Introduction . . . . . . . . . . . . . 65 II. Arguments for the Continuity of Plastids .
Book Synopsis Origin and Continuity of Cell Organelles by : J. Reinert
Download or read book Origin and Continuity of Cell Organelles written by J. Reinert and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of the series, on "The Stability of the Differentiated State" received many favorable reviews from the scientific community. Many readers seem to agree with us that publication of topical volumes is a worthwhile alternative to periodic compilations of rather unrelated, though up-to-date reviews. Production of topical volumes is however, plagued with one great difficulty, that of "author synchronization". This difficulty explains the lag between volumes 1 and 2 of the series. Nevertheless we hope that the present volume will be appreciated as a valuable source of information on its central topic: How do cell organelles originate, and what mechanisms assure their continuity? Tübingen, Berlin, Zürich, \V. BEERMANN, J. REINERT, H. URSPRUNG, Heidelberg H. -W. HA GENS Contents Assembly, Continuity, and Exchanges in Certain Cytoplasmic Membrane Systems by W. GORDON WHALEY, MARIANNE DAUWALDER, aüd ]OYCE E. KEPHART 1 I. The Nature of the Membrane. . . . . . H. The Assembly of Membranes . . . . . . 5 III. The Growth and Transfer of Membranes. 6 A. The Nuclear Envelopc . . . 6 B. The Endoplasmic Reticulum 13 C. The Golgi Apparatus . 17 D. The Plasma Membrane 28 E. Vacuoles and Vesicles 31 IV. Concluding Remarks 37 References . . . . . 38 Origin and Continuity of Mitochondria by ROBERT BAXTER 1. Introduction . . . . . . . . . . . . . 46 H. Mitochondrial Biogenesis : thc Machincry 46 III. Limitations of Mitochondrial Autonomy 50 IV. The Replication of Mitochondria 53 V. Discussion and Conclusion 58 Referenccs . . . . . . . . . 59 Origin and Continuity of Plastids by \VILFRIED STUBBE 1. Introduction . . . . . . . . . . . . . 65 II. Arguments for the Continuity of Plastids .
Download or read book Yeast written by Horst Feldmann and published by John Wiley & Sons. This book was released on 2012-09-06 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.
Book Synopsis Origin and Continuity of Cell Organelles by : J Reinert
Download or read book Origin and Continuity of Cell Organelles written by J Reinert and published by Springer. This book was released on 2014-01-15 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Mechanisms and Physiological Significance of Organelle Interactions and Cooperation by : Michael Schrader
Download or read book Molecular Mechanisms and Physiological Significance of Organelle Interactions and Cooperation written by Michael Schrader and published by Frontiers Media SA. This book was released on 2017-02-28 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eukaryotic cells contain distinct membrane-bound organelles, which compartmentalise cellular proteins to fulfil a variety of vital functions. Many organelles have long been regarded as isolated and static entities (e.g., peroxisomes, mitochondria, lipid droplets), but it is now evident that they display dynamic changes, interact with each other, share certain proteins and show metabolic cooperation and cross-talk. Despite great advances in the identification and characterisation of essential components and molecular mechanisms associated with the biogenesis and function of organelles, information on how organelles interact and are incorporated into metabolic pathways and signaling networks is just beginning to emerge. Organelle cooperation requires sophisticated targeting systems which regulate the proper distribution of shared proteins to more than one organelle. Organelle motility and membrane remodeling support organelle interaction and contact. This contact can be mediated by membrane proteins residing on different organelles which can serve as molecular tethers to physically link different organelles together. They can also contribute to the exchange of metabolites and ions, or act in the assembly of signaling platforms. In this regard organelle communication events have been associated with important cellular functions such as apoptosis, antiviral defense, organelle division/biogenesis, ROS metabolism and signaling, and various metabolic pathways such as breakdown of fatty acids or cholesterol biosynthesis. In this research topic we will focus on recent novel findings on the underlying molecular mechanisms and physiological significance of organelle interaction and cooperation with a particular focus on mitochondria, peroxisomes, endoplasmic reticulum, lysosomes and lipid droplets and their impact on the regulation of cellular homeostasis. Our understanding of how organelles physically interact and use cellular signaling systems to coordinate functional networks between each other is still in its infancy. Nevertheless recent discoveries of defined membrane structures such as the mitochondria-ER associated membranes (MAM) are revealing how membrane domains enriched in specific proteins transmit signals across organelle boundaries, allowing one organelle to influence the function of another. In addition to its role as a mediator between mitochondria and the ER, contacts between the MAM and peroxisomes contribute to antiviral signaling, and specialised regions of the ER are supposed to initiate peroxisome biogenesis, whereas intimate contacts between peroxisomes, lipid droplets and the ER mediate lipid metabolism. In line with these observations it is tempting to speculate that further physical contact sites between other organelles exist. Alternatively, novel regulated vesicle trafficking pathways between organelles (e.g., mitochondria to peroxisomes or lysosomes) have been discovered implying another mode of organelle communication. Identifying the key molecular players of such specialised membrane structures will be a prerequisite to understand how organelle communication is physically accomplished and will lead to the identification of new regulatory networks. In addition to the direct transmission of interorganellar information, cytosolic messenger systems (e.g., kinase/phosphatase systems or redox signaling) may contribute to the coordination of organelle functions. This research topic will integrate new findings from both modes of communication and will provide new perspectives for the functional significance of cross-talk among organelles. We would like to thank all the researchers who contributed their valuable work to this research topic. Furthermore, we are grateful to the reviewers and Associate Editors who contributed valuable comments and positive criticism to improve the contributions.
Book Synopsis Lysosomes by : Frederick R. Maxfield
Download or read book Lysosomes written by Frederick R. Maxfield and published by John Wiley & Sons. This book was released on 2016-06-22 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development
Author :Charles E. Bullerwell Publisher :Springer Science & Business Media ISBN 13 :364222380X Total Pages :481 pages Book Rating :4.6/5 (422 download)
Book Synopsis Organelle Genetics by : Charles E. Bullerwell
Download or read book Organelle Genetics written by Charles E. Bullerwell and published by Springer Science & Business Media. This book was released on 2011-10-26 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria and chloroplasts are eukaryotic organelles that evolved from bacterial ancestors and harbor their own genomes. The gene products of these genomes work in concert with those of the nuclear genome to ensure proper organelle metabolism and biogenesis. This book explores the forces that have shaped the evolution of organelle genomes and the expression of the genes encoded by them. Some striking examples of trends in organelle evolution explored here are the reduction in genome size and gene coding content observed in most lineages, the complete loss of organelle DNA in certain lineages, and the unusual modes of gene expression that have emerged, such as the extensive and essential mRNA editing that occurs in plant mitochondria and chloroplasts. This book places particular emphasis on the current techniques used to study the evolution of organelle genomes and gene expression.
