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Testing Multiple Hypotheses With Common Effect Direction Using The Closure Method
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Book Synopsis Permutation Tests for Stochastic Ordering and ANOVA by : Dario Basso
Download or read book Permutation Tests for Stochastic Ordering and ANOVA written by Dario Basso and published by Springer Science & Business Media. This book was released on 2009-04-20 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Permutation testing for multivariate stochastic ordering and ANOVA designs is a fundamental issue in many scientific fields such as medicine, biology, pharmaceutical studies, engineering, economics, psychology, and social sciences. This book presents new advanced methods and related R codes to perform complex multivariate analyses. The prerequisites are a standard course in statistics and some background in multivariate analysis and R software.
Book Synopsis Multiple Testing Problems in Pharmaceutical Statistics by : Alex Dmitrienko
Download or read book Multiple Testing Problems in Pharmaceutical Statistics written by Alex Dmitrienko and published by CRC Press. This book was released on 2009-12-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple c
Book Synopsis Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials by : Mark Chang
Download or read book Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials written by Mark Chang and published by CRC Press. This book was released on 2019-03-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these strategies are generally being considered on an individual trial basis and not as part of a fully integrated overall development program. Such optimization at the trial level is somewhat near-sighted and does not ensure cost, time, or development efficiency of the overall program. This book seeks to address this imbalance by establishing a statistical framework for overall/global clinical development optimization and providing tactics and techniques to support such optimization, including clinical trial simulations. Provides a statistical framework for achieve global optimization in each phase of the drug development process. Describes specific techniques to support optimization including adaptive designs, precision medicine, survival-endpoints, dose finding and multiple testing. Gives practical approaches to handling missing data in clinical trials using SAS. Looks at key controversial issues from both a clinical and statistical perspective. Presents a generous number of case studies from multiple therapeutic areas that help motivate and illustrate the statistical methods introduced in the book. Puts great emphasis on software implementation of the statistical methods with multiple examples of software code (both SAS and R). It is important for statisticians to possess a deep knowledge of the drug development process beyond statistical considerations. For these reasons, this book incorporates both statistical and "clinical/medical" perspectives.
Book Synopsis Social Science Research by : Anol Bhattacherjee
Download or read book Social Science Research written by Anol Bhattacherjee and published by CreateSpace. This book was released on 2012-04-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.
Book Synopsis Networks, Crowds, and Markets by : David Easley
Download or read book Networks, Crowds, and Markets written by David Easley and published by Cambridge University Press. This book was released on 2010-07-19 with total page 745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are all film stars linked to Kevin Bacon? Why do the stock markets rise and fall sharply on the strength of a vague rumour? How does gossip spread so quickly? Are we all related through six degrees of separation? There is a growing awareness of the complex networks that pervade modern society. We see them in the rapid growth of the internet, the ease of global communication, the swift spread of news and information, and in the way epidemics and financial crises develop with startling speed and intensity. This introductory book on the new science of networks takes an interdisciplinary approach, using economics, sociology, computing, information science and applied mathematics to address fundamental questions about the links that connect us, and the ways that our decisions can have consequences for others.
Book Synopsis Multiple Comparison Procedures by : Larry E. Toothaker
Download or read book Multiple Comparison Procedures written by Larry E. Toothaker and published by SAGE. This book was released on 1993 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you conduct research with more than two groups and want to find out if they are significantly different when compared two at a time, then you need Multiple Comparison Procedures. Using examples to illustrate major concepts, this concise volume is your guide to multiple comparisons. Toothaker thoroughly explains such essential issues as planned vs. post-hoc comparisons, stepwise vs. simultaneous test procedures, types of error rate, unequal sample sizes and variances, and interaction tests vs. cell mean tests.
Download or read book Energy Research Abstracts written by and published by . This book was released on 1994-11 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multiple Comparisons written by Jason Hsu and published by CRC Press. This book was released on 1996-02-01 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Comparisons introduces simultaneous statistical inference and covers the theory and techniques for all-pairwise comparisons, multiple comparisons with the best, and multiple comparisons with a control. The author describes confidence intervals methods and stepwise exposes abuses and misconceptions, and guides readers to the correct method for each problem. Discussions also include the connections with bioequivalence, drug stability, and toxicity studies Real data sets analyzed by computer software packages illustrate the applications presented.
Book Synopsis Scientific and Technical Aerospace Reports by :
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1994 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309377722 Total Pages :473 pages Book Rating :4.3/5 (93 download)
Book Synopsis Improving Diagnosis in Health Care by : National Academies of Sciences, Engineering, and Medicine
Download or read book Improving Diagnosis in Health Care written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2015-12-29 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Download or read book Applied Mechanics Reviews written by and published by . This book was released on 1974 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Research Methods in Human Development by : Paul C. Cozby
Download or read book Research Methods in Human Development written by Paul C. Cozby and published by WCB/McGraw-Hill. This book was released on 1989 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: For undergradute social science majors. A textbook on the interpretation and use of research. Annotation copyright Book News, Inc. Portland, Or.
Book Synopsis Calibration of Watershed Models by : Qingyun Duan
Download or read book Calibration of Watershed Models written by Qingyun Duan and published by John Wiley & Sons. This book was released on 2003-01-10 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published by the American Geophysical Union as part of the Water Science and Application Series, Volume 6. During the past four decades, computer-based mathematical models of watershed hydrology have been widely used for a variety of applications including hydrologic forecasting, hydrologic design, and water resources management. These models are based on general mathematical descriptions of the watershed processes that transform natural forcing (e.g., rainfall over the landscape) into response (e.g., runoff in the rivers). The user of a watershed hydrology model must specify the model parameters before the model is able to properly simulate the watershed behavior.
Book Synopsis Introduction to Property Testing by : Oded Goldreich
Download or read book Introduction to Property Testing written by Oded Goldreich and published by Cambridge University Press. This book was released on 2017-11-23 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extensive and authoritative introduction to property testing, the study of super-fast algorithms for the structural analysis of large quantities of data in order to determine global properties. This book can be used both as a reference book and a textbook, and includes numerous exercises.
Book Synopsis Experimental and Quasi-experimental Designs for Generalized Causal Inference by : William R. Shadish
Download or read book Experimental and Quasi-experimental Designs for Generalized Causal Inference written by William R. Shadish and published by Cengage Learning. This book was released on 2002 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sections include: experiments and generalised causal inference; statistical conclusion validity and internal validity; construct validity and external validity; quasi-experimental designs that either lack a control group or lack pretest observations on the outcome; quasi-experimental designs that use both control groups and pretests; quasi-experiments: interrupted time-series designs; regresssion discontinuity designs; randomised experiments: rationale, designs, and conditions conducive to doing them; practical problems 1: ethics, participation recruitment and random assignment; practical problems 2: treatment implementation and attrition; generalised causal inference: a grounded theory; generalised causal inference: methods for single studies; generalised causal inference: methods for multiple studies; a critical assessment of our assumptions.
Download or read book Fatigue Life written by V. S. Goel and published by . This book was released on 1986 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Neurological Bases of Language Disorders in Children by : Christy L. Ludlow
Download or read book The Neurological Bases of Language Disorders in Children written by Christy L. Ludlow and published by . This book was released on 1980 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
