Targeting Leukocyte Trafficking: Insights and Future Directions

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Publisher : Frontiers Media SA
ISBN 13 : 2889742857
Total Pages : 172 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Targeting Leukocyte Trafficking: Insights and Future Directions by : Helen Michelle McGettrick

Download or read book Targeting Leukocyte Trafficking: Insights and Future Directions written by Helen Michelle McGettrick and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroimmune Diseases

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Publisher : Springer
ISBN 13 : 3030195155
Total Pages : 822 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Neuroimmune Diseases by : Hiroshi Mitoma

Download or read book Neuroimmune Diseases written by Hiroshi Mitoma and published by Springer. This book was released on 2019-08-13 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

Leukocyte Trafficking in Homeostasis and Disease

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Leukocyte Trafficking in Homeostasis and Disease by : Joaquin Teixidó

Download or read book Leukocyte Trafficking in Homeostasis and Disease written by Joaquin Teixidó and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Leukocyte Trafficking

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Publisher : John Wiley & Sons
ISBN 13 : 9783527312283
Total Pages : 568 pages
Book Rating : 4.3/5 (122 download)

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Book Synopsis Leukocyte Trafficking by : Alf Hamann

Download or read book Leukocyte Trafficking written by Alf Hamann and published by John Wiley & Sons. This book was released on 2005-11-07 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kochman (scientific group leader, Institute of Microsystems Engineering, U. of Freiburg, Germany) presents 16 papers exploring the state of the art in micro process engineering. The text begins with fundamentals, including chapters on methods and technology; momentum and heat transfer; transport processes and exchange equipment; multiphase flow, evaporation, and condensation at the microscale; generation and multiphase flow of emulsions in microchannels; and chemical reactions in continuous-flow microstructured reactors. Next come discussions of design process and project management, simulation and analytical modeling for microreactor design, and integration of sensors and process-analytical techniques. Fabrication technologies and materials are considered in chapters on microfabrication in metals and polymers, silicon microfabrication for microfluidics, and microfabrication in ceramics and glass. The remaining papers look at industrial applications in the US, Europe, and Japan; as well as laboratory applications of microstructured devices in student education. Annotation :2006 Book News, Inc., Portland, OR (booknews.com).

New insights of immune cells in cardiovascular and metabolic disorders

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Publisher : Frontiers Media SA
ISBN 13 : 2832536972
Total Pages : 430 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis New insights of immune cells in cardiovascular and metabolic disorders by : Yingmei Feng

Download or read book New insights of immune cells in cardiovascular and metabolic disorders written by Yingmei Feng and published by Frontiers Media SA. This book was released on 2023-10-26 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New insights into mucosal-associated lymphoid tissues in fish

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Publisher : Frontiers Media SA
ISBN 13 : 2832524486
Total Pages : 312 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis New insights into mucosal-associated lymphoid tissues in fish by : Umasuthan Navaneethaiyer

Download or read book New insights into mucosal-associated lymphoid tissues in fish written by Umasuthan Navaneethaiyer and published by Frontiers Media SA. This book was released on 2023-06-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeting the Microenvironment Niche in Solid Tumors

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Publisher : Frontiers Media SA
ISBN 13 : 2889747727
Total Pages : 155 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Targeting the Microenvironment Niche in Solid Tumors by : Cirino Botta

Download or read book Targeting the Microenvironment Niche in Solid Tumors written by Cirino Botta and published by Frontiers Media SA. This book was released on 2022-04-29 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Perspectives on the Future of the Sociology of Aging

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Publisher : National Academies Press
ISBN 13 : 0309262453
Total Pages : 200 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Perspectives on the Future of the Sociology of Aging by : Panel on New Directions in Social Demography, Social Epidemiology, and the Sociology of Aging

Download or read book Perspectives on the Future of the Sociology of Aging written by Panel on New Directions in Social Demography, Social Epidemiology, and the Sociology of Aging and published by National Academies Press. This book was released on 2013-02-14 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The population of the United States is growing inexorably older. With birth rates historically low and life expectancy continuing to rise, the age distribution of the population in the United States is growing steadily older. This demographic shift is occurring at a time of major economic and social changes, which have important implications for the growing elderly population. Other changes, such as the move away from defined-benefit toward defined-contribution retirement plans, changes in some corporate and municipal pension plans as a result of market pressures, and the 2008 financial crisis precipitated by the crash of the housing market, all have economic implications for older people. They are also likely to make it more difficult for certain groups of future retirees to find their retirements at the level that they had planned and would like. To deal effectively with the challenges created by population aging, it is vital to first understand these demographic, economic, and social changes and, to the extent possible, their causes, consequences, and implications. Sociology offers a knowledge base, a number of useful analytic approaches and tools, and unique theoretical perspectives that can be important aids to this task. The Panel on New Directions in Social Demography, Social Epidemiology, and the Sociology of Aging was established in August 2010 under the auspices of the Committee on Population of the National Research Council to prepare a report that evaluates the recent contributions of social demography, social epidemiology, and sociology to the study of aging and seeks to identify promising new research in these fields. Perspectives on the Future of the Sociology of Aging provides candid and critical comments that will assist the institution in making the final published volume as sound as possible and to ensure that the volume meets institutional standards for objectivity, evidence, and responsiveness to the study charge.

Rutherford's Vascular Surgery and Endovascular Therapy, E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323581307
Total Pages : 2736 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Rutherford's Vascular Surgery and Endovascular Therapy, E-Book by : Anton N Sidawy

Download or read book Rutherford's Vascular Surgery and Endovascular Therapy, E-Book written by Anton N Sidawy and published by Elsevier Health Sciences. This book was released on 2018-04-03 with total page 2736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through nine outstanding editions, Rutherford's Vascular Surgery and Endovascular Therapy has been the gold standard text in this fast-changing, complex field. Published in association with the Society for Vascular Surgery, this state-of-the-art reference by Drs. Anton N. Sidawy and Bruce A. Perler is a must-have for vascular surgeons, interventionalists, vascular medicine specialists, and trainees, as well as general surgeons, interventional radiologists, and cardiologists that depend upon "Rutherford’s" in their practice. It offers authoritative guidance from the most respected and innovative global thought leaders and clinical and basic science experts in the diagnosis and treatment of circulatory disease. Incorporates medical, endovascular, and surgical treatment, as well as diagnostic techniques, decision making, and fundamental vascular biology. Features all vascular imaging techniques, offering a non-invasive evaluation of both the morphology and hemodynamics of the vascular system. Provides unparalleled insight from multidisciplinary leaders worldwide, who share their expertise on the most appropriate contemporary and future treatment of circulatory disease. Employs a full-color layout and images so you can view clinical and physical findings and operative techniques more vividly. Includes 40 new chapters incorporating a shorter, more focused format with a summary for each chapter that provides a quick access to key information – ideal for consultation situations as well as daily practice. Some of these chapters are organized in new sections dedicated to open operative exposure and vessel dissection techniques, diabetic foot, Pediatric Vascular Disease, and practice management issues; areas in the specialty that clinicians frequently face but seldom detailed in other vascular texts nor in earlier Rutherford editions. Covers hot topics such as endovascular therapy of aortic arch and thoracoabdominal aortic aneurysm disease, including the evolving management of aortic dissections.

Leucocyte Trafficking

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Publisher : Springer Science & Business Media
ISBN 13 : 3662053977
Total Pages : 258 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Leucocyte Trafficking by : A. Hamann

Download or read book Leucocyte Trafficking written by A. Hamann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Molecular and Functional Insights Into the Pulmonary Vasculature

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Publisher : Springer
ISBN 13 : 9783319684826
Total Pages : 86 pages
Book Rating : 4.6/5 (848 download)

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Book Synopsis Molecular and Functional Insights Into the Pulmonary Vasculature by : Kaushik Parthasarathi

Download or read book Molecular and Functional Insights Into the Pulmonary Vasculature written by Kaushik Parthasarathi and published by Springer. This book was released on 2018-01-09 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.

Adhesion Molecules: Function and Inhibition

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Publisher : Springer Science & Business Media
ISBN 13 : 376437974X
Total Pages : 314 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Adhesion Molecules: Function and Inhibition by : Klaus Ley

Download or read book Adhesion Molecules: Function and Inhibition written by Klaus Ley and published by Springer Science & Business Media. This book was released on 2007-08-16 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided. The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.

Nijkamp and Parnham's Principles of Immunopharmacology

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Publisher : Springer Nature
ISBN 13 : 3030108112
Total Pages : 888 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Nijkamp and Parnham's Principles of Immunopharmacology by : Michael J. Parnham

Download or read book Nijkamp and Parnham's Principles of Immunopharmacology written by Michael J. Parnham and published by Springer Nature. This book was released on 2019-12-10 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Universes in Delicate Balance: Chemokines and the Nervous System

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Publisher : Elsevier
ISBN 13 : 9780080520193
Total Pages : 404 pages
Book Rating : 4.5/5 (21 download)

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Book Synopsis Universes in Delicate Balance: Chemokines and the Nervous System by : R.M. Ransohoff

Download or read book Universes in Delicate Balance: Chemokines and the Nervous System written by R.M. Ransohoff and published by Elsevier. This book was released on 2002-04-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is commonly acknowledged that the nervous system and the immune system, those most complex of networks, share attributes beyond their intricacy. Elements common to the two systems include memory, connectivity, flexibility and developmental selection of cellular composition by a rigorous process involving widespread programmed cell death. There is one salient difference: the cells of the immune system are predominantly in constant motion, while post-mitotic neurons and glia are largely fixed in place. Therefore, chemokines, initially characterized as leukocyte chemoattractants, have for the last one and one-half decades been intensely and productively studied in the contexts of inflammation, immunity and hematopoietic development. Only recently have the two fields, neurobiology and immunology, displayed mutual interests in chemokines. This convergence of the two tribes of investigators was catalyzed by the finding that SDF-1 (now known as CXCL12) and its receptor, CXCR4, exerted significant and similar functions in development of both nervous and immune systems. Indeed CXCL12 and CXCR4 were required, in an uncannily similar fashion, for retention of pre-B lymphocytes at sites of maturation in the bone marrow and of neuronal progenitors in the external granule cell layer of the developing cerebellum. Recent reports indicate that chemoattraction of cerebellar granule cells through CXCR4 can be suppressed by reverse signaling initiated by binding of soluble eph receptors to transmembrane ephrin B, thereby establishing a link between chemokine action and a cardinal patterning system of the developing nervous system. As may be anticipated when a dam breaks, a massive influx of correlative observations in the nervous and immune systems is likely to ensue. This volume represents the state of current knowledge. To this end, introductory material for both systems is provided. Basic and advanced 'chemokinology' are presented. The recipe for making a nervous system (both ingredients and instructions for preparation) is described, as are the roles of chemokines and their receptors in making an immune system. Given their importance and complexity, CXCL12/CXCR4 interactions are separately treated in varying contexts. The field of 'neurobiology of chemokines' has not lain fallow during the last ten years. During much of this time the principal focus has been on neuroinflammation. Linking the immune and nervous systems are explanations of the functions of chemokines and their receptors for resident brain macrophages, the microglia, the unique cerebrovascular endothelium and angiogenesis. Understanding human disease is the goal of much of this research. New discoveries are being made and reported at a gratifying rate. It is expected that this volume will promote the steady production and application of useful new knowledge in this developing field. It provides a unique single-source database for basic neurobiology highlighting the fundamental aspects of chemokines and discussing the relations of chemokine science to animal models and human disease.

Lipid Rafts and Caveolae

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Publisher : John Wiley & Sons
ISBN 13 : 3527607501
Total Pages : 294 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Lipid Rafts and Caveolae by : Christopher J. Fielding

Download or read book Lipid Rafts and Caveolae written by Christopher J. Fielding and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail. Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include: Historical background Distinct structures and functions Structural basis Signaling Viral entry and virion budding Cholesterol transport Caveolins Lipid shells Cell polarity and intracellular trafficking Cancer cells Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.

Nuclear Cardiac Imaging

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Publisher : Oxford University Press, USA
ISBN 13 : 0199392099
Total Pages : 769 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Nuclear Cardiac Imaging by : Ami E. Iskandrian

Download or read book Nuclear Cardiac Imaging written by Ami E. Iskandrian and published by Oxford University Press, USA. This book was released on 2015-10-22 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive resource for nuclear cardiologists and nuclear clinicians on the technical, physiological, diagnostic and prognostic considerations of cardiac diagnostic techniques performed with the aid of radiopharmaceuticals.

Reviews in Gastrointestinal Cancers

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Publisher : Frontiers Media SA
ISBN 13 : 2832531458
Total Pages : 428 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Reviews in Gastrointestinal Cancers by : Fabrizio Bronte

Download or read book Reviews in Gastrointestinal Cancers written by Fabrizio Bronte and published by Frontiers Media SA. This book was released on 2023-08-02 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: