Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Systems Biology Of Cell Signaling
Download Systems Biology Of Cell Signaling full books in PDF, epub, and Kindle. Read online Systems Biology Of Cell Signaling ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Systems Biology of Cell Signaling by : James Ferrell
Download or read book Systems Biology of Cell Signaling written by James Ferrell and published by Garland Science. This book was released on 2021-09-28 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download
Book Synopsis Systems Biology of Cell Signaling by : Zhike Zi
Download or read book Systems Biology of Cell Signaling written by Zhike Zi and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Prof. Xing is in collaboration with ATCC (https://www.atcc.org/) on testing some of their cell lines in research. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
Book Synopsis Systems Biology for Signaling Networks by : Sangdun Choi
Download or read book Systems Biology for Signaling Networks written by Sangdun Choi and published by Springer Science & Business Media. This book was released on 2010-08-09 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.
Book Synopsis Understanding Cell Signaling by : James Ellsworth Ferrell
Download or read book Understanding Cell Signaling written by James Ellsworth Ferrell and published by Garland Science. This book was released on 2021 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: "All living cells continually detect and respond to external signals. This is true of prokaryotes, whether they are living alone or in biofilms, and it is even more manifestly true in multicellular eukaryotes, where communication between cells and coordination of the cells' behavior enables the organism to function as a unified whole. In large multicellular organisms like us humans, cells receive signals from their immediate neighbors through short-range signals like neurotransmitters and cell-surface molecules. They receive signals from more distant neighbors via longer-range diffusible molecules like morphogens, and from still-more distant neighbors by means of hormones that flow through the circulatory system. And they receive signals from the outside world via sense organs. Cells also monitor their own internal status, and there is a great deal of overlap between the cellular components involved in cell-cell communication and internal monitoring"--
Book Synopsis Systems Biology of Metabolic and Signaling Networks by : Miguel A. Aon
Download or read book Systems Biology of Metabolic and Signaling Networks written by Miguel A. Aon and published by Springer Science & Business Media. This book was released on 2013-10-22 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comprehensive. Essentially, they unravel the spatio-temporal unfolding of interacting mass-energy and information networks at the cellular and organ levels, as well as its modulation through activation or repression by signaling networks to produce a certain phenotype or (patho)physiological response. Starting with the historical roots, in thirteen chapters this work explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Book Synopsis A First Course in Systems Biology by : Eberhard Voit
Download or read book A First Course in Systems Biology written by Eberhard Voit and published by Garland Science. This book was released on 2017-09-05 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes. The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.
Book Synopsis Cellular Signal Processing by : Friedrich Marks
Download or read book Cellular Signal Processing written by Friedrich Marks and published by Garland Science. This book was released on 2017-05-17 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Book Synopsis An Introduction to Systems Biology by : Uri Alon
Download or read book An Introduction to Systems Biology written by Uri Alon and published by CRC Press. This book was released on 2006-07-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
Book Synopsis Control Theory and Systems Biology by : Pablo A. Iglesias
Download or read book Control Theory and Systems Biology written by Pablo A. Iglesias and published by MIT Press. This book was released on 2010 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.
Book Synopsis Computational Systems Biology by : Andres Kriete
Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Book Synopsis Immuno Systems Biology by : Kumar Selvarajoo
Download or read book Immuno Systems Biology written by Kumar Selvarajoo and published by Springer Science & Business Media. This book was released on 2013-10-01 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immuno Systems Biology aims to study the immune system in the more integrated manner on how cells and molecules participate at different system levels to the immune function. Through this book Kumar Selvarajoo introduces to physicists, chemists, computer scientists, biologists and immunologists the idea of an integrated approach to the understanding of mammalian immune system. Geared towards a researcher with limited immunological and computational analytical experience, the book provides a broad overview to the subject and some instruction in basic computational, theoretical and experimental approaches. The book links complex immunological processes with computational analysis and emphasizes the importance of immunology to the mammalian system.
Download or read book Cell Signalling written by John Hancock and published by Oxford University Press. This book was released on 2010-01-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Cell Signalling' presents a carefully structured introduction to this subject, introducing those conserved features which underlie many different extra-and intracellular signalling systems.
Book Synopsis Fundamentals of Systems Biology by : Markus W. Covert
Download or read book Fundamentals of Systems Biology written by Markus W. Covert and published by CRC Press. This book was released on 2017-10-19 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades biology has focused on decoding cellular processes one gene at a time, but many of the most pressing biological questions, as well as diseases such as cancer and heart disease, are related to complex systems involving the interaction of hundreds, or even thousands, of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on, carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book’s second half, where much more complicated network models are addressed—including transcriptional, signaling, metabolic, and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates, medical students, and biologists new to mathematical modeling) while still having much to offer experienced modelers--whether their interests are microbes, organs, whole organisms, diseases, synthetic biology, or just about any field that investigates living systems.
Book Synopsis Molecular Biology - Not Only for Bioinformaticians by : Wiesława Widłak
Download or read book Molecular Biology - Not Only for Bioinformaticians written by Wiesława Widłak and published by Springer. This book was released on 2013-12-05 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore indispensable for bioinformaticians. This book addresses beginners in molecular biology, especially computer scientists who would like to work as bioinformaticians. It presents basic processes in living organisms in a condensed manner. Additionally, principles of several high-throughput technologies in molecular biology, which need the assistance of bioinformaticians, are explained from a biological point of view. It is structured in the following 9 chapters: cells and viruses; protein structure and function; nucleic acids; DNA replication, mutations, and repair; transcription and posttranscriptional processes; synthesis and posttranslational modifications of proteins; cell division; cell signaling pathways; and high-throughput technologies in molecular biology.
Download or read book Systems Biology written by Edda Klipp and published by John Wiley & Sons. This book was released on 2016-03-28 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced textbook is tailored for an introductory course in Systems Biology and is well-suited for biologists as well as engineers and computer scientists. It comes with student-friendly reading lists and a companion website featuring a short exam prep version of the book and educational modeling programs. The text is written in an easily accessible style and includes numerous worked examples and study questions in each chapter. For this edition, a section on medical systems biology has been included.
Book Synopsis Computational Systems Biology by : Christina Kiel
Download or read book Computational Systems Biology written by Christina Kiel and published by Elsevier Inc. Chapters. This book was released on 2013-11-26 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter brings mammalian signal transduction to the center of quantitative and integrative sciences. Historically imbedded within human physiology, thanks to proteomics, interactomics, and molecular biology approaches, signaling is now far beyond the “black box” principle. However, despite the large amount of data available, we still have only limited insight into general design principles, and we lack knowledge on how cell type-specific signaling is achieved. Here, we summarize recent efforts in elucidating cell type-specific signaling, and in particular the role of protein abundances, signaling complexes and modules. We further discuss the potential of using synthetic biology approaches to decipher signaling networks. All of this is discussed in light of complementary quantitative mathematical modeling approaches. Signaling, more than any other discipline, needs computational biology to capture the dynamic systems behavior, and to reach its final goal: to be truly predictive for both the physiological and disease perturbed cellular conditions.
Download or read book Cell Signaling written by Wendell Lim and published by Taylor & Francis. This book was released on 2014-06-16 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa
