Surface Modifications Of Iron Oxide Nanoparticles For Magnetic Imaging And Diagnosis

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Surface Modifications of Iron Oxide Nanoparticles for Magnetic Imaging and Diagnosis

Author : Juanye Zhang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Surface Modifications of Iron Oxide Nanoparticles for Magnetic Imaging and Diagnosis by : Juanye Zhang

Download or read book Surface Modifications of Iron Oxide Nanoparticles for Magnetic Imaging and Diagnosis written by Juanye Zhang and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contrast agents are commonly used in magnetic resonance imaging (MRI) for their ability to selectively highlight or darken image brightness from different tissue components depending on their chemical nature. This work explores and discusses potential of colloidal iron oxide nanoparticles as non-toxic MRI contrast agents for diagnosis. Novel single-nanometer iron oxide (SNIO) nanoparticles exhibited contrast enhancement in T1-weighted MRI superior than commercially used gadolinium-based contrast agents, with unprecedentedly fast and clean renal clearance in inorganic colloidal nanoparticles. An approach for size determination based on small-angle X-ray scattering (SAXS) was developed, and understanding of particle size distribution led to successful development of alkyne-functionalized nanoparticles allowing for conjugation with biological cargos, creating a novel vehicle for drug delivery. SNIO-CBP, product from conjugating functionalized SNIO nanoparticles with a nature-inspired cyclic collagen-binding peptide (CBP) through newly developed preparatory copper-catalyzed alkyne-azide coupling CuAAC, exhibited binding affinity towards type I collagen, a natural indicator of fibrosis abundant in the extracellular matrix. SNIO-CBP was able to quickly detect hepatotoxin-induced and diet-induced non-alcoholic steatohepatitis (NASH) in mice through T1-weighted MRI upon intravenous administration. New formulations of hydrophilic iron oxide nanoparticles were explored. Tailored for quantitative ultra-short time-to-echo contrast-enhanced (QUTE-CE) MRI, catechol-coated iron oxide with 10 nm mean diameter was optimized; carboxymethyl dextran as a new ligand system was developed on SNIO and formation of nanoparticle clusters was observed, implying its potential for the emergent preclinical technique of magnetic particle imaging (MPI).

Magnetic Nanoparticles in Human Health and Medicine

Author : Costica Caizer
Publisher : John Wiley & Sons
ISBN 13 : 1119754747
Total Pages : 512 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Magnetic Nanoparticles in Human Health and Medicine by : Costica Caizer

Download or read book Magnetic Nanoparticles in Human Health and Medicine written by Costica Caizer and published by John Wiley & Sons. This book was released on 2021-09-08 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.

Magnetic Particle Imaging

Author : Tobias Knopp
Publisher : Springer Science & Business Media
ISBN 13 : 364204199X
Total Pages : 211 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Magnetic Particle Imaging by : Tobias Knopp

Download or read book Magnetic Particle Imaging written by Tobias Knopp and published by Springer Science & Business Media. This book was released on 2012-05-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.

Superparamagnetic Nanoparticles for Magnetic Resonance Imaging (MRI) Diagnosis

Author : Yunyu Shi
Publisher :
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.:/5 (749 download)

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Book Synopsis Superparamagnetic Nanoparticles for Magnetic Resonance Imaging (MRI) Diagnosis by : Yunyu Shi

Download or read book Superparamagnetic Nanoparticles for Magnetic Resonance Imaging (MRI) Diagnosis written by Yunyu Shi and published by . This book was released on 2006 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI), based on the nuclear magnetic resonance phenomenon, provides the possibility of detecting early malignant tumors with the assistance of appropriate contrast agents. Surface modification of superparamagnetic nanoparticles towards their use as MRI contrast agents has been the topic for many researchers, but implementation into fully functional in vivo procedures still remains as a challenging task. In the present study, high quality monocrystalline iron oxide nanoparticles have been synthesised and surface-modified with carboxymethylated dextran as well as polyethylene glycol (PEG).

Surface-modified Nanobiomaterials for Electrochemical and Biomedicine Applications

Author : Alain R. Puente-Santiago
Publisher : Springer Nature
ISBN 13 : 303055502X
Total Pages : 255 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Surface-modified Nanobiomaterials for Electrochemical and Biomedicine Applications by : Alain R. Puente-Santiago

Download or read book Surface-modified Nanobiomaterials for Electrochemical and Biomedicine Applications written by Alain R. Puente-Santiago and published by Springer Nature. This book was released on 2020-07-27 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Iron Oxide Nanoparticles for Biomedical Applications

Author : Sophie Laurent
Publisher : Elsevier
ISBN 13 : 9780081019252
Total Pages : 0 pages
Book Rating : 4.0/5 (192 download)

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Book Synopsis Iron Oxide Nanoparticles for Biomedical Applications by : Sophie Laurent

Download or read book Iron Oxide Nanoparticles for Biomedical Applications written by Sophie Laurent and published by Elsevier. This book was released on 2017-10-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine.

Nanostructure Science and Technology

Author : Richard W. Siegel
Publisher : Springer Science & Business Media
ISBN 13 : 9780792358541
Total Pages : 378 pages
Book Rating : 4.3/5 (585 download)

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Book Synopsis Nanostructure Science and Technology by : Richard W. Siegel

Download or read book Nanostructure Science and Technology written by Richard W. Siegel and published by Springer Science & Business Media. This book was released on 1999-09-30 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Timely information on scientific and engineering developments occurring in laboratories around the world provides critical input to maintaining the economic and technological strength of the United States. Moreover, sharing this information quickly with other countries can greatly enhance the productivity of scientists and engineers. These are some of the reasons why the National Science Foundation (NSF) has been involved in funding science and technology assessments comparing the United States and foreign countries since the early 1980s. A substantial number of these studies have been conducted by the World Technology Evaluation Center (WTEC) managed by Loyola College through a cooperative agreement with NSF. The National Science and Technology Council (NSTC), Committee on Technology's Interagency Working Group on NanoScience, Engineering and Technology (CT/IWGN) worked with WTEC to develop the scope of this Nanostucture Science and Technology report in an effort to develop a baseline of understanding for how to strategically make Federal nanoscale R&D investments in the coming years. The purpose of the NSTC/WTEC activity is to assess R&D efforts in other countries in specific areas of technology, to compare these efforts and their results to U. S. research in the same areas, and to identify opportunities for international collaboration in precompetitive research. Many U. S. organizations support substantial data gathering and analysis efforts focusing on nations such as Japan. But often the results of these studies are not widely available. At the same time, government and privately sponsored studies that are in the public domain tend to be "input" studies.

Surface Modifications of Iron Oxide Nanoparticles for Biological Applications

Author : Numpon Insin
Publisher :
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.:/5 (716 download)

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Book Synopsis Surface Modifications of Iron Oxide Nanoparticles for Biological Applications by : Numpon Insin

Download or read book Surface Modifications of Iron Oxide Nanoparticles for Biological Applications written by Numpon Insin and published by . This book was released on 2011 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron oxides magnetic nanoparticles (MPs) of high crystallinity, high magnetization, and size-monodispersity were synthesized with oleic acid as their native ligands. These hydrophobic and non-functionalized MPs have magnetic properties that are suitable for various biological applications. Surface modifications were studied for transferring these MPs into biological environments as well as transforming them into functional nanoparticles. Certain surface modifications of MPs, such as attaching silane groups and silica coating, lead to formation of more complex structures of superparamagnetic and fluorescent silica microspheres and nanostructures. These microspheres and nanostructures comprising MPs and semiconductor quantum dots (QDs) are useful tools for biological applications such as for magnetically controlling with fluorescent tracking of particles and for bimodal imaging. Surface modifications of MPs with hydrophobically-modified polyacrylic acid (mPAA) amphiphilic polymer and catechol-derivative surfactants resulted in hydrophilic MPs that are stable in physiological environment and small in their hydrodynamic size. These MPs are also designed to possess active functional groups that are necessary for further conjugations with proteins and molecules of interest. These hydrophilic and functional MPs are useful in biological applications such as magnetic resonance imaging and sensing applications.

Magnetic Nanoparticles in Biosensing and Medicine

Author : Nicholas J. Darton
Publisher : Cambridge University Press
ISBN 13 : 1107031095
Total Pages : 317 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Magnetic Nanoparticles in Biosensing and Medicine by : Nicholas J. Darton

Download or read book Magnetic Nanoparticles in Biosensing and Medicine written by Nicholas J. Darton and published by Cambridge University Press. This book was released on 2019-02-14 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing together topics from a wide range of disciplines, and featuring up-to-date examples of clinical usage and research applications, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine.

MRI

Author : Brian M. Dale
Publisher : John Wiley & Sons
ISBN 13 : 1119013038
Total Pages : 246 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis MRI by : Brian M. Dale

Download or read book MRI written by Brian M. Dale and published by John Wiley & Sons. This book was released on 2015-08-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

Ultrasound Assisted Non - Seeded Method on Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging Probe

Download Ultrasound Assisted Non - Seeded Method on Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging Probe PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (949 download)

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Book Synopsis Ultrasound Assisted Non - Seeded Method on Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging Probe by :

Download or read book Ultrasound Assisted Non - Seeded Method on Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging Probe written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Magnetic Nanoheterostructures

Author : Surender Kumar Sharma
Publisher : Springer Nature
ISBN 13 : 3030399230
Total Pages : 495 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Magnetic Nanoheterostructures by : Surender Kumar Sharma

Download or read book Magnetic Nanoheterostructures written by Surender Kumar Sharma and published by Springer Nature. This book was released on 2020-03-02 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics

Author : Sudip Mukherjee
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643277863
Total Pages : 50 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics by : Sudip Mukherjee

Download or read book Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics written by Sudip Mukherjee and published by Morgan & Claypool Publishers. This book was released on 2019-10-29 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.

Theranostic Iron-Oxide Based Nanoplatforms in Oncology

Author : Mohammad-Nabil Savari
Publisher : Springer Nature
ISBN 13 : 9819965071
Total Pages : 417 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Theranostic Iron-Oxide Based Nanoplatforms in Oncology by : Mohammad-Nabil Savari

Download or read book Theranostic Iron-Oxide Based Nanoplatforms in Oncology written by Mohammad-Nabil Savari and published by Springer Nature. This book was released on 2023-10-24 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.

Studies of Catechol-functionalized Multidentate Block Copolymer Strategy to Stabilize Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging

Download Studies of Catechol-functionalized Multidentate Block Copolymer Strategy to Stabilize Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging PDF Online Free

Author : Puzhen Li
Publisher :
ISBN 13 :
Total Pages : 95 pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Studies of Catechol-functionalized Multidentate Block Copolymer Strategy to Stabilize Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging by : Puzhen Li

Download or read book Studies of Catechol-functionalized Multidentate Block Copolymer Strategy to Stabilize Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging written by Puzhen Li and published by . This book was released on 2016 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) contrast agents play important roles in diagnosis and clinical applications. Particularly, superparamagnetic iron oxide nanoparticles (SNPs) with appropriate surface modification hold enormous promise as MRI contrast agents owning to their excellent biocompatibility. This thesis describes novel catechol-functionalized multidentate block copolymer (Cat-MDBC) strategy that enables the stabilization of SNPs with diameter ≤3.5 nm as effective MR bright imaging (T1-weighted) contrast agents. Atom transfer radical polymerization and post-modification methods allow for the synthesis of well-controlled Cat-MDBCs. They enable the stabilization of ultrasmall SNPs with diameter ≈3.5 nm (i.e. USNPs) through a biphasic ligand exchange process. The results from surface characteristics, colloidal stability in physiological properties, relaxivity properties, and in vitro MRI suggest that the USNPs coated with Cat-MDBC (Cat-MDBC/USNPs) can be a promising candidate for T1-MRI application. Further, extremely small SNPs with diameter ≈2 nm (i.e. ESNPs) coated with Cat-MDBC (Cat-MDBC/ESNPs) have better relaxivity properties as T1-MRI contrast agents, compared with the Cat-MDBC/USNP colloids; and more promisingly, they have the r2/r1 value comparable to clinically-used Gd3+-based contrast agents.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Author : Yashwant V Pathak
Publisher : Springer
ISBN 13 : 3030061159
Total Pages : 499 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Surface Modification of Nanoparticles for Targeted Drug Delivery by : Yashwant V Pathak

Download or read book Surface Modification of Nanoparticles for Targeted Drug Delivery written by Yashwant V Pathak and published by Springer. This book was released on 2019-03-11 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Nanoscale Magnetic Materials and Applications

Author : J. Ping Liu
Publisher : Springer Science & Business Media
ISBN 13 : 0387856005
Total Pages : 731 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Nanoscale Magnetic Materials and Applications by : J. Ping Liu

Download or read book Nanoscale Magnetic Materials and Applications written by J. Ping Liu and published by Springer Science & Business Media. This book was released on 2010-04-05 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoscale Magnetic Materials and Applications covers exciting new developments in the field of advanced magnetic materials. Readers will find valuable reviews of the current experimental and theoretical work on novel magnetic structures, nanocomposite magnets, spintronic materials, domain structure and domain-wall motion, in addition to nanoparticles and patterned magnetic recording media. Cutting-edge applications in the field are described by leading experts from academic and industrial communities. These include new devices based on domain wall motion, magnetic sensors derived from both giant and tunneling magnetoresistance, thin film devices in micro-electromechanical systems, and nanoparticle applications in biomedicine. In addition to providing an introduction to the advances in magnetic materials and applications at the nanoscale, this volume also presents emerging materials and phenomena, such as magnetocaloric and ferromagnetic shape memory materials, which motivate future development in this exciting field. Nanoscale Magnetic Materials and Applications also features a foreword written by Peter Grünberg, recipient of the 2007 Nobel Prize in Physics.