Structure in Protein Chemistry

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Publisher : Garland Science
ISBN 13 : 1136843515
Total Pages : 832 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis Structure in Protein Chemistry by : Jack Kyte

Download or read book Structure in Protein Chemistry written by Jack Kyte and published by Garland Science. This book was released on 2006-11-01 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure in Protein Chemistry

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Author :
Publisher : Garland Science
ISBN 13 : 1136843507
Total Pages : 1576 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis Structure in Protein Chemistry by : Jack Kyte

Download or read book Structure in Protein Chemistry written by Jack Kyte and published by Garland Science. This book was released on 2006-11-01 with total page 1576 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Protein Chemistry

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110566281
Total Pages : 336 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Protein Chemistry by : Lars Backman

Download or read book Protein Chemistry written by Lars Backman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-12-02 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This class-tested textbook gives an overview of the structure and functions of proteins and explains how amino acids form a defined structural entity with specific properties. The authors also introduce modern methods for purification and separation of proteins as well as different techniques for analyzing their structural and functional properties. A separate part of the book is devoted to enzymes and kinetics of enzymatic reactions.

Principles of Protein Structure

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Publisher : Springer Science & Business Media
ISBN 13 : 1461261376
Total Pages : 328 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Principles of Protein Structure by : G.E. Schulz

Download or read book Principles of Protein Structure written by G.E. Schulz and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses.

Current Research in Protein Chemistry

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Publisher : Academic Press
ISBN 13 : 0323137768
Total Pages : 635 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Current Research in Protein Chemistry by : Villafranc

Download or read book Current Research in Protein Chemistry written by Villafranc and published by Academic Press. This book was released on 1990-04-28 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Research in Protein Chemistry: Techniques, Structure, and Function reviews new techniques and methods for determining the structure and function of proteins. Topics covered include protein folding and stability, chimeric proteins, amino acid and peptide analysis, mass spectrometric methods, and protein sequencing techniques. This book is divided into six sections comprised of 55 chapters. The discussion begins with a description of microwave irradiation that uses Teflon-Pyrex tubes for protein hydrolysis, followed by the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow explore mass spectrometry, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. Chapters focus on the crystal structure of human interleukin-1a, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins. This book will be of value to students and researchers interested in protein chemistry.

Fundamentals of Protein Structure and Function

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Publisher : Springer
ISBN 13 : 331919920X
Total Pages : 521 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Fundamentals of Protein Structure and Function by : Engelbert Buxbaum

Download or read book Fundamentals of Protein Structure and Function written by Engelbert Buxbaum and published by Springer. This book was released on 2015-11-27 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Current Research in Protein Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 0323139442
Total Pages : 635 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Current Research in Protein Chemistry by : Villafranc

Download or read book Current Research in Protein Chemistry written by Villafranc and published by Elsevier. This book was released on 2012-12-02 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Research in Protein Chemistry: Techniques, Structure, and Function focuses on the techniques and methods used for determining the structure and function of proteins. Topics covered range from protein folding and stability to catalysis by chimeric proteins, amino acid and peptide analysis, applications of mass spectrometry to peptide and protein analysis, and protein sequencing. This book is divided into six sections encompassing 55 chapters. The first chapter describes a novel method for protein hydrolysis by means of microwave irradiation that uses Teflon-Pyrex tubes. This is followed by a discussion of the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow focus on mass spectrometric methods, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. The crystal structure of human interleukin-1alpha, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins are considered. The reader is also introduced to peptide mapping and internal sequencing of proteins from acrylamide gels, new approaches to covalent sequence analysis, alkaline denaturation of hemoglobin, and measurements of disulfide bond stabilities in protein folding intermediates. Students and researchers interested in protein chemistry will find this book extremely helpful.

Protein Structure and Function

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Publisher : New Science Press
ISBN 13 : 0878936637
Total Pages : 220 pages
Book Rating : 4.8/5 (789 download)

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Book Synopsis Protein Structure and Function by : Gregory A. Petsko

Download or read book Protein Structure and Function written by Gregory A. Petsko and published by New Science Press. This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Lipoproteins, Apolipoproteins, and Lipases

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Publisher : Academic Press
ISBN 13 : 0080582184
Total Pages : 489 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Lipoproteins, Apolipoproteins, and Lipases by :

Download or read book Lipoproteins, Apolipoproteins, and Lipases written by and published by Academic Press. This book was released on 1994-03-10 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains eight chapters that present both new and reviewed information fundamental to a clear understanding of lipid catabolism and transport at the molecular level. Three-dimensional structures of important serum lipoproteins, apolipoproteins, and lipases, utilizing X-ray data when available, are emphasized, and an attempt is made to relate structures to function. - Amphipathic helix - Apolipoprotein E - Lipophorin - Structure of serum albumin - Lipid binding proteins - Apolipoprotein B - Low-density lipoprotein

Advances in Protein Chemistry and Structural Biology

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Publisher : Academic Press
ISBN 13 : 0123819636
Total Pages : 241 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Advances in Protein Chemistry and Structural Biology by : Alexander McPherson

Download or read book Advances in Protein Chemistry and Structural Biology written by Alexander McPherson and published by Academic Press. This book was released on 2010-09-09 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale. Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission

Techniques in Protein Chemistry

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Publisher :
ISBN 13 : 9780126820010
Total Pages : 636 pages
Book Rating : 4.8/5 (2 download)

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Book Synopsis Techniques in Protein Chemistry by : Tony E. Hugli

Download or read book Techniques in Protein Chemistry written by Tony E. Hugli and published by . This book was released on 1989 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proteins

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Publisher : Macmillan
ISBN 13 : 9780716770305
Total Pages : 534 pages
Book Rating : 4.7/5 (73 download)

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Book Synopsis Proteins by : Thomas E. Creighton

Download or read book Proteins written by Thomas E. Creighton and published by Macmillan. This book was released on 1993 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on a combined basis of chronology and of structural and functional hierarchy, This comprehensive text describes all aspects of proteins--biosynthesis, evolution, dynamics, ligand binding, catalysis, and energy transduction--not just their structures. This edition (first was 1984) is thoroughly updated--especially in the area of protein biosynthesis--and features end-of-chapter exercises and problems, many of which require the student to consult the cited literature in order to obtain the answer. Annotation copyright by Book News, Inc., Portland, OR

Fibrous Proteins: Coiled-Coils, Collagen and Elastomers

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780120342709
Total Pages : 588 pages
Book Rating : 4.3/5 (427 download)

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Book Synopsis Fibrous Proteins: Coiled-Coils, Collagen and Elastomers by : David A.D. Parry

Download or read book Fibrous Proteins: Coiled-Coils, Collagen and Elastomers written by David A.D. Parry and published by Gulf Professional Publishing. This book was released on 2005-05-06 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibrous Protein: Coiled-Coils, Collagen and Elastomers is the first of a three-part series on Fibrous Proteins. The books are based on a very successful workshop in Alpbach, Austria on the general topic of Fibrous Proteins that gave rise to the award winning issue of Journal of Structural Biology. Part II will contain an extensive discussion of Molecular Motors and Muscle, Part III on Amyloids, Prions and Beta Proteins. Advances in Protein Chemistry is available online on ScienceDirect - full-text online of volumes 53 onwards. Reveals new structural and functional aspects of fibrous proteins Based on Fibrous Protein workshop in Alpbach, Austria that gave rise to 2003 Nobel Prize winners in Chemistry

Techniques in Protein Chemistry

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Publisher : Elsevier
ISBN 13 : 008054228X
Total Pages : 933 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Techniques in Protein Chemistry by :

Download or read book Techniques in Protein Chemistry written by and published by Elsevier. This book was released on 1997-07-21 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the Series:"The mainly sharp scientific focus of this set of snapshots is a credit to both the contricutors and the editorial team."--Biotechnology and Applied Biochemistry Techniques in Protein Chemistry VIII is the latest volume in this successful series. As a valuable bench-top reference tool for protein chemists, the ten section sof the book are divided by subject area to show the reader which techniques are currently applied to particular problems in protein science. This approach reflects current trends in which specific instruments and methodologies are used in several different areas.* * The book features the latest advances in protein chemistry methodologies in the following areas:* Protein sequencing and amino acid analysis* Mass spectral analysis of peptides and proteins* Posttranslational processing* High-sensitivity protein and peptide separations* Protein folding and NMR* Functional domain analysis* Protein design and engineering* Three-dimensional protein structure

Chemistry of Natural Protein Fibers

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Publisher : Springer Science & Business Media
ISBN 13 : 1461341094
Total Pages : 431 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Chemistry of Natural Protein Fibers by : R. S. Asquith

Download or read book Chemistry of Natural Protein Fibers written by R. S. Asquith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume arose originally from the complaints of the editor's students, both undergraduate and postgraduate, that there was no modern book on protein fibers which told enough about protein science and chemical tech nologies related to fibers. By and large this is probably a reasonable cri de coeur. The undergraduate on a technological course, lacking information on the basic scientific techniques used to carry out the research on which his fiber technology is based, can find it difficult to obtain this information. The pure science undergraduate often lacks knowledge of the application of these techniques in protein fiber technology. The young graduates, com mencing research related to some aspect of protein fibers, are drawn from a wide range of scientific disciplines, having been trained as biochemists, chemists, physicists, technologists, and histologists, to name but a few. Generally these new research workers pass through a preliminary "lost" period in which they have to evaluate their background in relation to the wide and differing fields of research in protein fiber science to which they are now exposed. As time goes on they then either develop a wide knowledge covering science and technology or remain in a specific part of their original discipline, with a narrow knowledge of its application in the field of the research degree they are taking.

Prediction of Protein Structure and the Principles of Protein Conformation

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Publisher : Springer Science & Business Media
ISBN 13 : 1461315719
Total Pages : 796 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Prediction of Protein Structure and the Principles of Protein Conformation by : G.D. Fasman

Download or read book Prediction of Protein Structure and the Principles of Protein Conformation written by G.D. Fasman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prediction of the conformation of proteins has developed from an intellectual exercise into a serious practical endeavor that has great promise to yield new stable enzymes, products of pharmacological significance, and catalysts of great potential. With the application of predic tion gaining momentum in various fields, such as enzymology and immunology, it was deemed time that a volume be published to make available a thorough evaluation of present methods, for researchers in this field to expound fully the virtues of various algorithms, to open the field to a wider audience, and to offer the scientific public an opportunity to examine carefully its successes and failures. In this manner the practitioners of the art could better evaluate the tools and the output so that their expectations and applications could be more realistic. The editor has assembled chapters by many of the main contributors to this area and simultaneously placed their programs at three national resources so that they are readily available to those who wish to apply them to their personal interests. These algorithms, written by their originators, when utilized on pes or larger computers, can instantaneously take a primary amino acid sequence and produce a two-or three-dimensional artistic image that gives satisfaction to one's esthetic sensibilities and food for thought concerning the structure and function of proteins. It is in this spirit that this volume was envisaged.