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Structure Function Relationships Of Human Pathogenic Viruses
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Book Synopsis Structure-Function Relationships of Human Pathogenic Viruses by : Andreas Holzenburg
Download or read book Structure-Function Relationships of Human Pathogenic Viruses written by Andreas Holzenburg and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions. The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Furthermore Structure-Function Relationships of Human Pathogenic Viruses illustrates in a single volume the fundamental processes involved in viral life cycles using up-to-date information from research laboratories around the world. Knowledge of these processes is crucial to develop rationales for the design of future drugs. The timeliness of the data and the comprehensive yet concise approach this book takes in order to present the world of viral pathogens should make it a frontrunner in higher education and R&D.
Book Synopsis Structure and Physics of Viruses by : Mauricio G. Mateu
Download or read book Structure and Physics of Viruses written by Mauricio G. Mateu and published by Springer Science & Business Media. This book was released on 2013-06-04 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Structural Virology by : Mavis Agbandje-McKenna
Download or read book Structural Virology written by Mavis Agbandje-McKenna and published by Royal Society of Chemistry. This book was released on 2010-11-11 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic design. Structural Virology covers a wide range of topics and is split into three sections. The first discusses the vast biophysical methodologies used in structural virology, including sample production and purification, confocal microscopy, mass spectrometry, negative-stain and cryo-electron microscopy, X-ray crystallography and nuclear magnetic resonance spectroscopy. The second discusses the role of virus capsid protein structures in determining the functional roles required for receptor recognition, cellular entry, capsid assembly, genome packaging and mechanisms of host immune system evasion. The last section discusses therapeutic strategies based on virus protein structures, including the design of antiviral drugs and the development of viral capsids as vehicles for foreign gene delivery. Each topic covered will begin with a review of the current literature followed by a more detailed discussion of experimental procedures, a step in the viral life cycle, or strategies for therapeutic development. With contributions from experts in the field of structural biology and virology this exceptional monograph will appeal to biomedical scientists involved in basic and /or applied research on viruses. It also provides up-to-date reference material for students entering the field of structural virology as well as scientists already familiar with the area.
Download or read book Virus Structure written by and published by Elsevier. This book was released on 2003-10-02 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses. Covers viral assembly using heterologous expression systems and cell extracts Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment Includes information on structural studies on antibody/virus complexes
Book Synopsis Viruses: Essential Agents of Life by : Günther Witzany
Download or read book Viruses: Essential Agents of Life written by Günther Witzany and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.
Book Synopsis Human Retroviruses by : Bryan Cullen
Download or read book Human Retroviruses written by Bryan Cullen and published by Oxford University Press. This book was released on 1993 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Book Synopsis Molecular Virology of Human Pathogenic Viruses by : Wang-Shick Ryu
Download or read book Molecular Virology of Human Pathogenic Viruses written by Wang-Shick Ryu and published by Academic Press. This book was released on 2016-03-30 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control
Book Synopsis Physical Virology by : Urs F. Greber
Download or read book Physical Virology written by Urs F. Greber and published by Springer. This book was released on 2019-07-17 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores a new challenge in virology: to understand how physical properties of virus particles (virions) and viruses (infected cells) affect the course of an infection. Insights from the emerging field of physical virology will contribute to understanding of the physical nature of viruses and cells, and will open new ways for anti-viral interference. Nine chapters and an editorial written by physicists, chemists, biologists and computational experts describe how virions serve as trail blazers in uncharted territory of cells. The authors outline how particles change in composition as they interact with host cells. Such virus dynamics are crucial for virus entry into cells and infection. It influences the modern concepts of virus-host interactions, viral lineages and evolution. The volume gives numerous up-to-date examples of modern virology and provides a fascinating read for researchers, clinicians and students in the field of infectious diseases.
Book Synopsis Human Cytomegalovirus by : Thomas E. Shenk
Download or read book Human Cytomegalovirus written by Thomas E. Shenk and published by Springer Science & Business Media. This book was released on 2008-05-09 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease.
Book Synopsis Fenner and White's Medical Virology by : Christopher J. Burrell
Download or read book Fenner and White's Medical Virology written by Christopher J. Burrell and published by Academic Press. This book was released on 2016-11-09 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. Features updated and expanded coverage of pathogenesis and immunity Contains the latest laboratory diagnostic methods Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control
Book Synopsis Cell Biology of Herpes Viruses by : Klaus Osterrieder
Download or read book Cell Biology of Herpes Viruses written by Klaus Osterrieder and published by Springer. This book was released on 2017-05-20 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herpes viruses are widely distributed in nature, causing disease in organisms as diverse as bivalves and primates, including humans. Each virus appears to have established a long-standing relationship with its host, and the viruses have the ability to manipulate and control the metabolism of host cells, as well as innate and adaptive antiviral immune responses. Herpes viruses maintain themselves within hosts in a latent state resulting in virus persistence for years – usually for the life span of the hosts. Herpes viruses comprise a large number of pathogens with diverse cellular targets and biological consequences of infection. What they have in common is their structure and the fact that they establish a dormant (latent) infection in their hosts that usually persists for life. The reviews here will highlight the general principles of herpes virus infection, with equal attention to overall principle and important difference. Also, the cell type- and life-style dependent differences in the establishment and maintenance of virus persistence will be covered.
Book Synopsis Classifying Drinking Water Contaminants for Regulatory Consideration by : National Research Council
Download or read book Classifying Drinking Water Contaminants for Regulatory Consideration written by National Research Council and published by National Academies Press. This book was released on 2001-08-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Americans drink many gallons of tap water every day, but many of them question the safety of tap water every day as well. In fact, devices have been created to filter tap water directly before reaching cups. It's true; however, that the provision and management of safe drinking water throughout the United States have seen triumphs in public health since the beginning of the 20th century. Although, advances in water treatment, source water protection efforts, and the presence of local, state, and federal regulatory protection have developed over the years, water in the United States still contain chemical, microbiological, and other types of contaminants at detectable and at times harmful levels. This in addition to the growth of microbial pathogens that can resist traditional water treatment practices have led to the question: Where and how should the U.S. government focus its attention and limited resources to ensure safe drinking water supplies for the future? To deal with these issues the Safe Drinking Water Act (SDWA) Amendments of 1996 Safe included a request that the U.S. Environmental Protection Agency (EPA) publish a list of unregulated chemical and microbial contaminants and contaminant groups every five years that are or could pose risks in the drinking water of public water systems. The first list, called the Drinking Water Contaminant Candidate List (CCL), was published in March 1998. The main function of the CCL is to provide the basis for deciding whether to regulate at least five new contaminants from the CCL every five years. However, since additional research and monitoring need to be conducted for most of the contaminants on the 1998 CCL, the list is also used to prioritize these related activities. Classifying Drinking Water Contaminants for Regulatory Consideration is the third report by the Committee on Dinking Water Contaminants with the purpose of providing advice regarding the setting of priorities among drinking water contaminants in order to identify those contaminants that pose the greatest threats to public health. The committee is comprised of 14 volunteer experts in water treatment engineering, toxicology, public health, epidemiology, water and analytical chemistry, risk assessment, risk communication, public water system operations, and microbiology and is jointly overseen by the National Research Council's (NRC'S) Water Science and Technology Board and Board on Environmental Studies and Toxicology. In this report the committee needed to readdress its second report as well as explore the feasibility of developing and using mechanisms for identifying emerging microbial pathogens for research and regulatory activities. The promotion of public health remains the guiding principle of the committee's recommendations and conclusions in this report.
Book Synopsis The Epstein-Barr Virus by : M. A. Epstein
Download or read book The Epstein-Barr Virus written by M. A. Epstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's lymphoma and probably to nasopharyngeal carcinoma. In addition, continuous human lymphoid cell lines initiated and maintained by the transform ing function of the virus genome provide a laboratory tool with wide and ever-growing applications. Innumerable papers on the Epstein-Barr virus have ap peared over recent years and reports of work with this agent now constitute a veritable flood. The present book provides the first and only comprehensive, authoritative over-view of all aspects of the virus by authors who have been the original and major contributors in their particular disciplines. A complete and up-to-date survey of this unique and important agent is thus provided which should be of great interest to experts, teachers, and students engaged in cancer research, virology, immunology, molecular biology, epide miology, and cell culture. Where topics have been dealt with from more than one of these viewpoints, some inevitable overlap and duplication has resulted; although this has been kept to a minimum, it has been retained in some places because of positive usefulness.
Book Synopsis Viral Pathogenesis by : Michael G. Katze
Download or read book Viral Pathogenesis written by Michael G. Katze and published by Academic Press. This book was released on 2015-12-30 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis Provides a fresh perspective on the approaches used to understand how viruses cause disease Features molecular profiling techniques, whole genome sequencing, and innovative computational methods Highlights the use of contemporary approaches and the insights they provide to the field
Book Synopsis Varicella-zoster Virus by : Ann M. Arvin
Download or read book Varicella-zoster Virus written by Ann M. Arvin and published by Springer Nature. This book was released on 2022-11-01 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume provides insights about the molecular virology, pathoenesis of infection and host responses to varicella-zoster virus, which is a medically important human herpesvirus. The chapters not only discuss genetics and molecular evolution of the virus, but also new structure-based knowledge on the functions of viral glycoproteins. Further, the authors illustrate how mechanisms from the virus are used to take over and remodel host cells during pathogeneis. These mechanisms also enable viral modulation of host cells and evasion of the host immune response. Part of these evasion and survival strategies, is the reaction to triggered host cell responses like autophagy, the stress response, modulation of apoptosis and other cell death pathways. This hands-on knowledge is crucial for students and clinicians in Virology, Immunology, and Infectious Diseases. Chapter "Common features between stroke following varicella in children and stroke following herpes zoster in adults" is available open access under a Creative Commons Attribution 4.0 International License via Springerlink.com.
