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Author : Guy M. P. Coates
Publisher :
ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (911 download)
Download or read book Structure-function Relationships in Biological Ion Channels written by Guy M. P. Coates and published by . This book was released on 2001 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alfred Maelicke
Publisher : Springer Science & Business Media
ISBN 13 : 364274155X
Total Pages : 670 pages
Book Rating : 4.6/5 (427 download)
Download or read book Molecular Biology of Neuroreceptors and Ion Channels written by Alfred Maelicke and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: This workshop was the second of this series held on the island of santorini in the Cycladic Sea. The first one ("Mechanism of Action of the Nicotinic Acetylcholine Receptor", NATO ASI Se ries H, vol. 10) took place in May 1986 and focused on what was at the time the best studied of all neuroreceptors. This second one, held only two years later, demonstrates the im mense progress achieved since then in the field of neurorecep tors and ion channels. Molecular cloning techniques have now made available the primary structures of a whole array of ion channel proteins, and this in turn has shed light on some gen eral principles of the structure-function relationships of these central elements of intercellular communication. The purpose of this workshop was to explore the common ele ments in gene and protein structure of already cloned ion channel proteins, and to assess the status of other cloning projects in progress. It explicitly focused on very recently published and unpublished results. All participants kept to these goals thereby demonstrating the very value of such work shops for the progress of science.
Author : Osei Kwame Asamoah
Publisher :
ISBN 13 :
Total Pages : 350 pages
Book Rating : 4.:/5 ( download)
Download or read book An Optical Approach to Structure-function Relationships in Voltage-gated Ion Channels written by Osei Kwame Asamoah and published by . This book was released on 2004 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Angel Anne Yanagihara
Publisher :
ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (18 download)
Download or read book A Novel Approach to the Study of Structure-function Relationships in the Sodium Ion Channel written by Angel Anne Yanagihara and published by . This book was released on 1997 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Isabelle Huys
Publisher : Leuven University Press
ISBN 13 : 9789058673534
Total Pages : 240 pages
Book Rating : 4.6/5 (735 download)
Download or read book Structure-function Relationship of K+ Ion Channel Toxins written by Isabelle Huys and published by Leuven University Press. This book was released on 2004 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Many fundamental processes underlying nerve and muscle excitation, hormone secretion, learning and memory, cell proliferation, sensory transduction and regulation of blood pressure and osmotic balance, are attributed to a div"
![Download Probing the Structure - Function Relationships of Ion Channels that Form Large [Beta] Barrels PDF Online Free](https://books.google.com/books/content/images/frontcover/ud8gOAAACAAJ?fife=w200-h370)
Author : Jinming Song
Publisher :
ISBN 13 :
Total Pages : 438 pages
Book Rating : 4.:/5 (397 download)
Download or read book Probing the Structure - Function Relationships of Ion Channels that Form Large [Beta] Barrels written by Jinming Song and published by . This book was released on 1997 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David J. Aidley
Publisher : Cambridge University Press
ISBN 13 : 9780521498821
Total Pages : 324 pages
Book Rating : 4.4/5 (988 download)
Download or read book Ion Channels written by David J. Aidley and published by Cambridge University Press. This book was released on 1996-08-13 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.
Author : James N. C. Kew
Publisher :
ISBN 13 : 0199296758
Total Pages : 586 pages
Book Rating : 4.1/5 (992 download)
Download or read book Ion Channels written by James N. C. Kew and published by . This book was released on 2010 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are intimately involved in the everyday physiological functions that enable us to live a full and varied life. When disease strikes, malfunction of ion channels or their dependent is often involved, either as the cause or the effect of the illness. Thus, billions of dollars have been, and still are being, invested in research to understand the physiological and pathophysiological functions of ion channels in an attempt to develop novel therapeutic treatments for a wide range of diseases. This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts. Part one is an introductory overview of the ion channel superfamily and the generic aspects of ion channel function. This part also reviews the methodologies by which ion channel function can be studied from the perspective of performing detailed biophysical characterization through to the deployment of high throughput approaches for identifying novel ion channel ligands. Part two of the book provides an in-depth review of the individual ion channel subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion Channels, and Polymodal-Gated Ion Channels, with each chapter focused on specific family members. These chapters have been written by world leading experts and provide a detailed overview of the structure, biophysics, localization, pharmacology, physiology, and disease relevance of each particular ion channel subfamily. Reviewing both the basic principles of ion channel function and providing a detailed up-to-date review of the phsyiological and pharmacological aspects of individual ion channel sub-families, this book constitutes both an excellent introduction to the field for non-specialists, as well as a highly valuable reference text for experienced researchers already working in the ion channel area.
Author : Donald Eugene Elmore
Publisher :
ISBN 13 :
Total Pages : 342 pages
Book Rating : 4.:/5 (437 download)
Download or read book Investigations of Ion Channel Structure-function Relationships Using Molecular Modeling and Experimental Biochemistry written by Donald Eugene Elmore and published by . This book was released on 2004 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. Peter Tieleman
Publisher :
ISBN 13 :
Total Pages : 207 pages
Book Rating : 4.:/5 (669 download)
Download or read book Simulation Approaches to Ion Channel Structure-function Relationships written by D. Peter Tieleman and published by . This book was released on 2001 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rob D. Coalson
Publisher :
ISBN 13 : 9781498717830
Total Pages : 350 pages
Book Rating : 4.7/5 (178 download)
Download or read book Modeling Structure-Function Relations in Ion Channels written by Rob D. Coalson and published by . This book was released on with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Shin-Ho Chung
Publisher : Springer Science & Business Media
ISBN 13 : 0387689192
Total Pages : 657 pages
Book Rating : 4.3/5 (876 download)
Download or read book Biological Membrane Ion Channels written by Shin-Ho Chung and published by Springer Science & Business Media. This book was released on 2007-11-13 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and biosensors, as well as advanced undergraduate and graduate students in biology and the physical sciences.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Christopher Ahern
Publisher : Springer
ISBN 13 : 1493928457
Total Pages : 159 pages
Book Rating : 4.4/5 (939 download)
Download or read book Novel Chemical Tools to Study Ion Channel Biology written by Christopher Ahern and published by Springer. This book was released on 2015-09-17 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology. Capturing the contributions and innovations of renowned laboratory researchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. Novel Chemical Tools to Study Ion Channel Biology, part of the bestselling Advances in Experimental Medicine and Biology series is ideal for researchers and advanced students interested in biochemistry, biophysics, fluorometry, electrophysiology, and chemical biology. .
Author : Piero P. Foa
Publisher : Springer Science & Business Media
ISBN 13 : 1461225965
Total Pages : 605 pages
Book Rating : 4.4/5 (612 download)
Download or read book Ion Channels and Ion Pumps written by Piero P. Foa and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omnis cellula e cellula, "every cell from a cell," was dogma to the 19th century cellular physiologist and the cornerstone of Virchow's Cellular pathologie. "Spread out a cell into a layer and you will find that, in ceasing to be a cell, it has ceased to act as such," wrote the British 1 physiologist G . R. Lewes more than a century age. "The cell remains vital as long as its wall remains intact . . . " keeping its content "pure and clear" and thus preserving the "vital principle" within, echoed Claude 2 Bernard a few years later. The notion of the cell membrane as a pro tecting envelope held sway until it became clear that it could not account for the "coalescence" of poorly differentiated embryonic "vesicles" and for their transformation into "cell-like structures" capable of auto regulation and yet subject to what the grandfather of one of us defined as the "federal obligations imposed by the whole organism. ,,3 A new concept was needed, and soon the membrane was described as a structure capable of uniting as well as separating adjacent cells. Morphologic evidence for this dual function was obtained several years later when the electron microscope revealed the existence of tight and gap junc tions which, acting as intercellular bonds and channels, allowed the cells to communicate with one another and thus coordinate their biologic activities.
Author : Valentin K. Gribkoff
Publisher : John Wiley & Sons
ISBN 13 : 0470429895
Total Pages : 505 pages
Book Rating : 4.4/5 (74 download)
Download or read book Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels written by Valentin K. Gribkoff and published by John Wiley & Sons. This book was released on 2008-12-09 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.
Author : James D. Stockand
Publisher : Springer Science & Business Media
ISBN 13 : 1597450952
Total Pages : 208 pages
Book Rating : 4.5/5 (974 download)
Download or read book Ion Channels written by James D. Stockand and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diverse applications in this volume range from the study of allosteric regulation of ion channel activity using a classic mutagenesis approach, to the study of channel subunit stoichiometry using a novel biophysical approach based on fluorescence resonance energy transfer. Highlights include methods for heterologous expression of ion channels in cells, for determining channel structure-function, and for studying channel regulation.
