Standards for Ocular Toxicology and Inflammation

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Author :
Publisher : Springer
ISBN 13 : 3319783645
Total Pages : 218 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Standards for Ocular Toxicology and Inflammation by : Brian C. Gilger

Download or read book Standards for Ocular Toxicology and Inflammation written by Brian C. Gilger and published by Springer. This book was released on 2018-08-31 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems

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Author :
Publisher : Elsevier
ISBN 13 : 032399282X
Total Pages : 910 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems by : Wanda M. Haschek

Download or read book Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems written by Wanda M. Haschek and published by Elsevier. This book was released on 2024-03-05 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. - Presents updated chapters on systems toxicologic pathology, including new chapter on olfactory - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions to highlight difficult concepts with clear illustrations

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

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Author :
Publisher : Elsevier
ISBN 13 : 0323984622
Total Pages : 1074 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Nonclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy - Includes the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Dermal and Ocular Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1000124886
Total Pages : 664 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Dermal and Ocular Toxicology by : David W. Hobson

Download or read book Dermal and Ocular Toxicology written by David W. Hobson and published by CRC Press. This book was released on 2020-11-25 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.

Crises in Oil, Gas and Petrochemical Industries

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Author :
Publisher : Elsevier
ISBN 13 : 0323951554
Total Pages : 494 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Crises in Oil, Gas and Petrochemical Industries by : Mohammad Reza Rahimpour

Download or read book Crises in Oil, Gas and Petrochemical Industries written by Mohammad Reza Rahimpour and published by Elsevier. This book was released on 2023-07-13 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crises in Oil, Gas and Petrochemical Industries: Disasters and Environmental Challenges provides an overview of both natural and manmade disasters occurring in oil, gas and petrochemical industries while also covering special solutions based on their types. This volume includes the effects of natural disasters such as earthquakes, floods and hurricanes as well as manmade incidents including fire events, explosions and the release of dust and toxic substances on various related units and plants. In addition, the long-term side effects on both humans and the environment resulted from these industries are presented. Problems such as releasing wastes and venting gases into the environment and challenges from overusing the natural resources and producing noise pollutants are also discussed in detail. - Introduces the effects of natural disasters on the oil, gas and petrochemical industries - Describes the effect of manmade disasters on oil, gas and petrochemical industries - Discusses the long-term side effects of oil, gas and petrochemical units on humans and the environments

Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323319858
Total Pages : 425 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book by : Frederick T. Fraunfelder

Download or read book Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book written by Frederick T. Fraunfelder and published by Elsevier Health Sciences. This book was released on 2014-09-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for ophthalmologists, optometrists and busy clinicians, Drug-Induced Ocular Side Effects provides the clinically relevant information you need to diagnose and manage chemical and drug-related ocular problems. An easily accessible format, meticulous revisions and comprehensive coverage of all drugs’ generic and trade names, primary uses, ocular and systemic side effects, and clinical significance make this best-selling resource the ideal reference for quick, on-the-spot consultation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Manage any challenge in ocular toxicology with extensive coverage of principles of therapy; ocular drug delivery; methods to evaluate drug-induced visual side effects; and the role of electrophysiology and psychophysics. Benefit from the masterful guidance and global perspective of world authorities in the field who provide need-to-know information on all aspects of ocular toxicology—all in one concise reference. Confer with the WHO classification system to determine whether a particular side effect is certain, probable, or likely to occur. Zero in on the key information you need to know with highly templated, concise chapters. Apply the latest knowledge and treatments for newly recognized Adverse Drug Reactions (ADR). Identify which ADR’s are clinically relevant and what to do about them. Experience clinical scenarios with vivid clarity through a wealth of new and updated clinical photographs that provide unmatched, visual diagnostic guidance. Recognize and avoid drug-induced ocular side effects with data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden). Stay up to date and provide state-of-the-art care with the latest information on approved medications. Access the complete contents online at Expert Consult.

Toxicology Research Projects Directory

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Author :
Publisher :
ISBN 13 :
Total Pages : 624 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicology Research Projects Directory by :

Download or read book Toxicology Research Projects Directory written by and published by . This book was released on 1980-04 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540898905
Total Pages : 576 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Drug Discovery and Evaluation: Methods in Clinical Pharmacology by : H.Gerhard Vogel

Download or read book Drug Discovery and Evaluation: Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

The impact of clinical and environmental toxicological exposures and eye health

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832550819
Total Pages : 127 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The impact of clinical and environmental toxicological exposures and eye health by : Anat Galor

Download or read book The impact of clinical and environmental toxicological exposures and eye health written by Anat Galor and published by Frontiers Media SA. This book was released on 2024-06-26 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is often times referred to as the ”window to the soul”. This is relevant to the practice of medicine as many systemic disorders can present with eye manifestations that can be detected by routine ophthalmic examination and the findings used to help physicians in the diagnosis and management of an individual patient. Conditions with potential eye manifestations include infections, metabolic disorders, auto-immune diseases, and exposure, to name a few. With respect to the latter, various toxicological exposures, whether environmental or clinical, can manifest with eye findings. Some associations are well characterized, such as crystalline retinal deposits that can occur with prolonged tamoxifen use, while others are less well described or understood.

WHO Guidelines for Indoor Air Quality

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Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis WHO Guidelines for Indoor Air Quality by :

Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Primary Care - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323937004
Total Pages : 1618 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Primary Care - E-Book by : Terry Mahan Buttaro

Download or read book Primary Care - E-Book written by Terry Mahan Buttaro and published by Elsevier Health Sciences. This book was released on 2024-03-02 with total page 1618 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Advanced Practice**There's no better preparation for Nurse Practitioners and other adult primary care practitioners! Buttaro's Primary Care: Interprofessional Collaborative Practice, 7th Edition provides the concise yet thorough information that you need in today's fast-paced, interprofessional, collaborative environment. With authorship reflecting both academic and clinical expertise, this comprehensive, evidence-based primary care text/reference shows you how to deliver effective, truly interdisciplinary health care. It covers every major adult disorder seen in the outpatient office setting and features a unique interprofessional collaborative approach with referral and "Red Flag" highlights and more. New to this edition are chapters on health equity, public health preparedness, endocannabinoids, and self-care. - Comprehensive, evidence-based, accurate, and current content provides a complete foundation in the primary care of adults for NP students, including students in Doctor of Nursing Practice (DNP) programs, and reflects the latest research and national and international guidelines. - UNIQUE! Interprofessional collaborative approach equips you for interprofessional collaborative practice in the contemporary healthcare environment. - Consistent chapter format and features reflect the systematic approach used in adult primary care practice to promote improved clinical judgment skills, facilitate learning, and foster quick clinical reference. - UNIQUE! Referral/Consultation highlights indicate when the NP should collaborate with, or refer to, other providers. - UNIQUE! Emergency Referral highlights indicate when the NP should refer the patient for urgent/emergent care. - UNIQUE! Red Flag highlights indicate issues not to be missed. - UNIQUE! Initial Diagnostics boxes provide quick reference to key decision-making content.

A Comprehensive Guide to Toxicology in Preclinical Drug Development

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Author :
Publisher : Academic Press
ISBN 13 : 0123878160
Total Pages : 903 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Comprehensive Guide to Toxicology in Preclinical Drug Development by : Ali S. Faqi

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-10-18 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source

Handbook of Toxicology of Chemical Warfare Agents

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Author :
Publisher : Academic Press
ISBN 13 : 0128190914
Total Pages : 1322 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Toxicology of Chemical Warfare Agents by : Ramesh C Gupta

Download or read book Handbook of Toxicology of Chemical Warfare Agents written by Ramesh C Gupta and published by Academic Press. This book was released on 2020-03-31 with total page 1322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Toxicology of Chemical Warfare Agents, Third Edition, covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the second edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a new chapter on emergency preparedness, coverage of the chemical warfare agents used in Syria, the use of the Novichok agent in the UK, and more. - Unites world-leading experts to bring you cutting-edge, agent-specific information on Chemical Warfare Agents (CWA) and their adverse effects on human and animal health, and the environment - Provides you with all the information you need on CWA modes of action, detection, prevention, therapeutic treatment and countermeasures - New to this edition: a full update to reflect the most recent advances in the field and new chapters on emergency preparedness, the chemical warfare agents used in Syria, and the use of the Novichok agent in the UK

Public Health Consequences of E-Cigarettes

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Author :
Publisher : National Academies Press
ISBN 13 : 030946837X
Total Pages : 775 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Public Health Consequences of E-Cigarettes by : National Academies of Sciences, Engineering, and Medicine

Download or read book Public Health Consequences of E-Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Toxicity Bibliography

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Author :
Publisher :
ISBN 13 :
Total Pages : 916 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Bibliography by :

Download or read book Toxicity Bibliography written by and published by . This book was released on 1975 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1439890145
Total Pages : 1016 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Handbook of Toxicology by : Michael J. Derelanko

Download or read book Handbook of Toxicology written by Michael J. Derelanko and published by CRC Press. This book was released on 2014-03-07 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r

Veterinary and Human Toxicology

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Author :
Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Veterinary and Human Toxicology by :

Download or read book Veterinary and Human Toxicology written by and published by . This book was released on 2001 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: