Splines And Compartment Models: An Introduction

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Publisher : World Scientific
ISBN 13 : 9814522244
Total Pages : 349 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Splines And Compartment Models: An Introduction by : Karl-ernst Erich Biebler

Download or read book Splines And Compartment Models: An Introduction written by Karl-ernst Erich Biebler and published by World Scientific. This book was released on 2013-07-23 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given.In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.

Splines and Compartment Models

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Author :
Publisher : World Scientific
ISBN 13 : 9814522236
Total Pages : 349 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Splines and Compartment Models by : Karl-Ernst Biebler

Download or read book Splines and Compartment Models written by Karl-Ernst Biebler and published by World Scientific. This book was released on 2013 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given. In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.

Geometric Modeling

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Publisher : Springer Science & Business Media
ISBN 13 : 3642764045
Total Pages : 291 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Geometric Modeling by : Hans Hagen

Download or read book Geometric Modeling written by Hans Hagen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on lectures presented at an international workshop on geometric modeling held at Hewlett Packard GmbH in Boblingen, FRG, in June 1990. International experts from academia and industry were selected to speak on the most interesting topics in geometric modeling. The resulting papers, published in this volume, give a state-of-the-art survey of the relevant problems and issues. The following topics are discussed: - Methods for constructing surfaces on surfaces: four different solutions to the multidimen sional problem of constructing an interpolant from surface data are provided. - Surfaces in solid modeling: current results on the implementation of free-fonn solids in three well established solid models are reviewed. - Box splines and applications: an introduction to box spline methods for the representation of surfaces is given. Basic properties of box splines are derived, and refinement and evaluation methods for box splines are presented in detail. Shape preserving properties, the construction of non-rectangular box spline surfaces, applications to surface modeling, and imbedding problems, are discussed. - Advanced computer graphics techniques for volume visualization: the steps to be executed in the visualization process of volume data are described and tools are discussed that assist in handling this data. - Rational B-splines: an introduction to the representation of curves and surfaces using rational B-splines is given, together with a critical evaluation of their potential for industrial application.

Spline Functions

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Publisher : SIAM
ISBN 13 : 1611973902
Total Pages : 420 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis Spline Functions by : Larry L. Schumaker

Download or read book Spline Functions written by Larry L. Schumaker and published by SIAM. This book was released on 2015-01-01 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes in detail the key algorithms needed for computing with spline functions and illustrates their use in solving several basic problems in numerical analysis, including function approximation, numerical quadrature, data fitting, and the numerical solution of PDE's. The focus is on computational methods for bivariate splines on triangulations in the plane and on the sphere, although both univariate and tensor-product splines are also discussed. The book contains numerous examples and figures to illustrate the methods and their performance. All of the algorithms in the book have been coded in a separate MATLAB package available for license. The package can be used to run all of the examples in the book and also provides readers with the essential tools needed to create software for their own applications. In addition to the included bibliography, a list of over 100 pages of additional references can be found on the book's website.

Modelling and Control in Biomedical Systems

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Publisher : Pergamon
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Modelling and Control in Biomedical Systems by : Claudio Cobelli

Download or read book Modelling and Control in Biomedical Systems written by Claudio Cobelli and published by Pergamon. This book was released on 1989 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. This volume provides a complete and up-to-date review of the recent developments and trends relating to modelling and control in biomedical systems in research, diagnosis and therapy. Focus is placed on methodological issues relevant to modelling and control as well as to the various physiological systems of the organism visited from a control viewpoint. Contains 98 papers.

13th International Symposium on Process Systems Engineering – PSE 2018, July 1-5 2018

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Publisher : Elsevier
ISBN 13 : 0444642420
Total Pages : 2620 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis 13th International Symposium on Process Systems Engineering – PSE 2018, July 1-5 2018 by : Mario R. Eden

Download or read book 13th International Symposium on Process Systems Engineering – PSE 2018, July 1-5 2018 written by Mario R. Eden and published by Elsevier. This book was released on 2018-07-19 with total page 2620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Process Systems Engineering brings together the international community of researchers and engineers interested in computing-based methods in process engineering. This conference highlights the contributions of the PSE community towards the sustainability of modern society and is based on the 13th International Symposium on Process Systems Engineering PSE 2018 event held San Diego, CA, July 1-5 2018. The book contains contributions from academia and industry, establishing the core products of PSE, defining the new and changing scope of our results, and future challenges. Plenary and keynote lectures discuss real-world challenges (globalization, energy, environment and health) and contribute to discussions on the widening scope of PSE versus the consolidation of the core topics of PSE. - Highlights how the Process Systems Engineering community contributes to the sustainability of modern society - Establishes the core products of Process Systems Engineering - Defines the future challenges of Process Systems Engineering

Population Pharmacokinetic Models with Time Dependent Covariates

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Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Population Pharmacokinetic Models with Time Dependent Covariates by : Lang Li

Download or read book Population Pharmacokinetic Models with Time Dependent Covariates written by Lang Li and published by . This book was released on 2001 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Energy metabolism

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Publisher : Frontiers E-books
ISBN 13 : 288919308X
Total Pages : 133 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Energy metabolism by : Patrick Christian Even

Download or read book Energy metabolism written by Patrick Christian Even and published by Frontiers E-books. This book was released on 2014-11-03 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.

Surface Modeling

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Publisher : CRC Press
ISBN 13 : 9781439817599
Total Pages : 711 pages
Book Rating : 4.8/5 (175 download)

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Book Synopsis Surface Modeling by : Tian-Xiang Yue

Download or read book Surface Modeling written by Tian-Xiang Yue and published by CRC Press. This book was released on 2011-02-04 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although GIS provides powerful functionality for spatial analysis, data overlay and storage, these spatially oriented systems lack the ability to represent temporal dynamics, which is a major impediment to its use in surface modeling. However, rapid development of computing technology in recent years has made real-time spatial analysis and real-time data visualization become realizable. Based on newly developed methods, Surface Modeling: High Accuracy and High Speed Methods explores solutions to big-error and slow-efficiency problems, two critical challenges that have long plagued those working in with geographical information system (GIS) and computer-aided design (CAD). By developing high accuracy and high speed methods for surface modeling, the book builds a bridge between the mathematical-oriented theory of surface modeling and the user-oriented application where the user is actually able to retrieve information on the method itself. The author examines a novel method of high accuracy surface modeling (HASM) in terms of the fundamental theorem of surfaces. He then analyzes the coefficient matrix and develops an adaptive method of HASM (HASM-AM), a multi-grade method of HASM (HASM-MG), and an adjustment method of HASM (HASM-AD). He uses numerical tests and real world studies to demonstrate that HASM-AM, HASM-MG, and HASM-AD have highly accelerated computational speed, especially for simulations with huge computational work. Building on this, the book discusses a HASM-based method for dynamic simulation (HASM-FDS), and then applies HASM methods to simulate terrains, climate change, ecosystem change, land cover, and soil properties. It demonstrates HASM's potential for simulating population distribution, human carrying capacity, ecosystem services, ecological diversity, change detection, and wind velocity. The book concludes with a discussion of the problems that exist in surface modeling on a global level and evaluates possible solutions to these problems.

A Conversation With the Brain: Can We Speak Its Language?

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Publisher : Frontiers Media SA
ISBN 13 : 2889660672
Total Pages : 155 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis A Conversation With the Brain: Can We Speak Its Language? by : Alejandro Barriga-Rivera

Download or read book A Conversation With the Brain: Can We Speak Its Language? written by Alejandro Barriga-Rivera and published by Frontiers Media SA. This book was released on 2020-10-12 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Multicompartment Models of Uptake and Excretion of Chemicals

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Publisher :
ISBN 13 :
Total Pages : 58 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Multicompartment Models of Uptake and Excretion of Chemicals by : V. Zitko

Download or read book Multicompartment Models of Uptake and Excretion of Chemicals written by V. Zitko and published by . This book was released on 1986 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proceedings

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Publisher :
ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 2002 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Journal of the American Statistical Association

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Publisher :
ISBN 13 :
Total Pages : 896 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Journal of the American Statistical Association by :

Download or read book Journal of the American Statistical Association written by and published by . This book was released on 2009 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt:

R for Data Science

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Publisher : "O'Reilly Media, Inc."
ISBN 13 : 1491910364
Total Pages : 521 pages
Book Rating : 4.4/5 (919 download)

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Book Synopsis R for Data Science by : Hadley Wickham

Download or read book R for Data Science written by Hadley Wickham and published by "O'Reilly Media, Inc.". This book was released on 2016-12-12 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how to use R to turn raw data into insight, knowledge, and understanding. This book introduces you to R, RStudio, and the tidyverse, a collection of R packages designed to work together to make data science fast, fluent, and fun. Suitable for readers with no previous programming experience, R for Data Science is designed to get you doing data science as quickly as possible. Authors Hadley Wickham and Garrett Grolemund guide you through the steps of importing, wrangling, exploring, and modeling your data and communicating the results. You'll get a complete, big-picture understanding of the data science cycle, along with basic tools you need to manage the details. Each section of the book is paired with exercises to help you practice what you've learned along the way. You'll learn how to: Wrangle—transform your datasets into a form convenient for analysis Program—learn powerful R tools for solving data problems with greater clarity and ease Explore—examine your data, generate hypotheses, and quickly test them Model—provide a low-dimensional summary that captures true "signals" in your dataset Communicate—learn R Markdown for integrating prose, code, and results

Mixed Effects Models for Complex Data

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Publisher : CRC Press
ISBN 13 : 9781420074086
Total Pages : 431 pages
Book Rating : 4.0/5 (74 download)

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Book Synopsis Mixed Effects Models for Complex Data by : Lang Wu

Download or read book Mixed Effects Models for Complex Data written by Lang Wu and published by CRC Press. This book was released on 2009-11-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.

Comprehensive Biomedical Physics

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Author :
Publisher : Newnes
ISBN 13 : 0444536337
Total Pages : 4052 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Comprehensive Biomedical Physics by :

Download or read book Comprehensive Biomedical Physics written by and published by Newnes. This book was released on 2014-07-25 with total page 4052 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomedical Physics, Ten Volume Set is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Canadian Technical Report of Fisheries and Aquatic Sciences

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Publisher :
ISBN 13 :
Total Pages : 62 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Canadian Technical Report of Fisheries and Aquatic Sciences by :

Download or read book Canadian Technical Report of Fisheries and Aquatic Sciences written by and published by . This book was released on 1986 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes abstracts and introduction in French.