Spinal Cord Injury (SCI) Repair Strategies

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Author :
Publisher : Woodhead Publishing
ISBN 13 : 0081028083
Total Pages : 346 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Spinal Cord Injury (SCI) Repair Strategies by : Giuseppe Perale

Download or read book Spinal Cord Injury (SCI) Repair Strategies written by Giuseppe Perale and published by Woodhead Publishing. This book was released on 2019-10-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. Covers current and future repair strategies for spinal cord injury repair Focuses on key research trends, clinics, biology and engineering Provides fundamentals on regenerative engineering and tissue engineering

Indwelling Neural Implants

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Publisher : CRC Press
ISBN 13 : 9781420009309
Total Pages : 296 pages
Book Rating : 4.0/5 (93 download)

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Book Synopsis Indwelling Neural Implants by : William M. Reichert

Download or read book Indwelling Neural Implants written by William M. Reichert and published by CRC Press. This book was released on 2007-12-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

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Author :
Publisher : Academic Press
ISBN 13 : 0128198362
Total Pages : 646 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma by : Michael Fehlings

Download or read book Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma written by Michael Fehlings and published by Academic Press. This book was released on 2022-02-17 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Textbook of Neural Repair and Rehabilitation

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Publisher : Cambridge University Press
ISBN 13 : 1107011671
Total Pages : 693 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Neural Repair and Rehabilitation by : Michael Selzer

Download or read book Textbook of Neural Repair and Rehabilitation written by Michael Selzer and published by Cambridge University Press. This book was released on 2014-04-24 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Therapeutic Strategies to Spinal Cord Injury

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Author :
Publisher : MDPI
ISBN 13 : 3038974064
Total Pages : 239 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Therapeutic Strategies to Spinal Cord Injury by : Pavla Jendelova

Download or read book Therapeutic Strategies to Spinal Cord Injury written by Pavla Jendelova and published by MDPI. This book was released on 2018-11-29 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Therapeutic Strategies to Spinal Cord Injury" that was published in IJMS

Neuroprotection

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Publisher : BoD – Books on Demand
ISBN 13 : 1838804390
Total Pages : 350 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Neuroprotection by : Matilde Otero-Losada

Download or read book Neuroprotection written by Matilde Otero-Losada and published by BoD – Books on Demand. This book was released on 2020-11-26 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.

Paraplegia

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Publisher : BoD – Books on Demand
ISBN 13 : 1789855411
Total Pages : 216 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Paraplegia by : José Juan Antonio Ibarra Arias

Download or read book Paraplegia written by José Juan Antonio Ibarra Arias and published by BoD – Books on Demand. This book was released on 2021-05-12 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, diverse research areas have developed novel approaches to overcome dysfunctions after a spinal cord injury (SCI). Even though motor restoration attracts the most clinical attention, sensory, autonomic, and mental health are also aspects fundamental to improving the quality of life of SCI patients. Over four sections of therapeutic, rehabilitation, and technological approaches, this book examines preclinical and clinical studies using mesenchymal stem cells and pharmacological or electrical stimulation strategies. Chapters also address the impact of paraplegia and associated loss of autonomic functions, including bowel and sexual dysfunction, as well as the convergence of new technologies aimed at providing postural support and enhancing mobility.

Locomotor Training

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0195342089
Total Pages : 200 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Locomotor Training by : Susan J. Harkema

Download or read book Locomotor Training written by Susan J. Harkema and published by Oxford University Press, USA. This book was released on 2011 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Locomotor training is aiming to promote recovery after spinal cord injury via activation of the neuromuscular system below the level of the lesion

Spinal Cord Injury Therapy

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789841615
Total Pages : 173 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Spinal Cord Injury Therapy by : José Juan Antonio Ibarra Arias

Download or read book Spinal Cord Injury Therapy written by José Juan Antonio Ibarra Arias and published by BoD – Books on Demand. This book was released on 2019-11-27 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal cord injury (SCI) is one of the main pathologies causing significant loss of neurological function. Therefore, a variety of pharmacological and non-pharmacological therapies are the aims of several studies. To provide the best care, it is important to know and understand the therapeutic approaches that have shown important progress in this topic. This book contains eight chapters that are divided into three sections: Introduction, Pharmacological Therapies, and Non-Pharmacological Therapies. The authors of the chapters deal with the pathophysiology of SCI, the effect of antioxidant and immunosuppressive agents, stem cell-based therapies, the use of cultured cells for transference or transplantation, and the application of non-invasive modalities (transcutaneous electrical spinal cord stimulation, etc.) for SCI rehabilitation.

CNS Regeneration

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Author :
Publisher : Elsevier
ISBN 13 : 9780080556987
Total Pages : 526 pages
Book Rating : 4.5/5 (569 download)

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Book Synopsis CNS Regeneration by : Jeffrey Kordower

Download or read book CNS Regeneration written by Jeffrey Kordower and published by Elsevier. This book was released on 2011-04-28 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS

Recovery of Motor Function Following Spinal Cord Injury

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535124978
Total Pages : 332 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Recovery of Motor Function Following Spinal Cord Injury by : Heidi Fuller

Download or read book Recovery of Motor Function Following Spinal Cord Injury written by Heidi Fuller and published by BoD – Books on Demand. This book was released on 2016-08-17 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restoration of motor function following spinal cord injury is a complex and challenging task. By reviewing emerging cellular, pharmacological, rehabilitative, as well as surgical approaches, this book seeks to highlight promising therapeutic strategies for the repair and regeneration of motor circuitry. The multidisciplinary nature of these approaches illustrates various routes to bridging the gap between the bench and the bedside and to identify the challenges that must be overcome in order to bring about a viable therapeutic strategy for spinal cord injury patients.

Spinal Cord Medicine

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451154275
Total Pages : 1899 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Spinal Cord Medicine by : Denise I. Campagnolo

Download or read book Spinal Cord Medicine written by Denise I. Campagnolo and published by Lippincott Williams & Wilkins. This book was released on 2011-12-07 with total page 1899 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and practical reference is the perfect resource for the medical specialist treating persons with spinal cord injuries. The book provides detail about all aspects of spinal cord injury and disease. The initial seven chapters present the history, anatomy, imaging, epidemiology, and general acute management of spinal cord injury. The next eleven chapters deal with medical aspects of spinal cord damage, such as pulmonary management and the neurogenic bladder. Chapters on rehabilitation are followed by nine chapters dealing with diseases that cause non-traumatic spinal cord injury. A comprehensive imaging chapter is included with 30 figures which provide the reader with an excellent resource to understand the complex issues of imaging the spine and spinal cord.

Spinal Cord Injury

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Author :
Publisher : Newnes
ISBN 13 : 0444535071
Total Pages : 656 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Spinal Cord Injury by : Joost Verhaagen

Download or read book Spinal Cord Injury written by Joost Verhaagen and published by Newnes. This book was released on 2012-12-31 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological approaches, molecular target discovery, and the use of olfactory ensheathing cells, stem cells, and precursor cells. Organized in five sections, the book begins with an overview of the development, maturation, biomechanics, and anatomy of the spinal cord before proceeding with a discussion of clinical diagnosis and prognosis as well as natural recovery, ambulation, and function following spinal cord injury. It then examines clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; medical, surgical and rehabilitative management of spinal cord trauma; and some new approaches for improving recovery in patients, including restoration of function by electrical stimulation, locomotor training, and the use of robotics. Other chapters cover cell transplantation, artificial scaffolds, experimental pharmacological interventions, and molecular and combinatorial strategies for repairing the injured spinal cord. This volume should be of interest to neuroscience and clinical neurology research specialists and practicing neurologists. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities

Spinal Cord Injury

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Author :
Publisher : National Academies Press
ISBN 13 : 0309165202
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Spinal Cord Injury by : Institute of Medicine

Download or read book Spinal Cord Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2005-07-27 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are still no cures and the challenge of restoring function in the wake of spinal cord injuries remains extremely complex. Spinal Cord Injury examines the future directions for research with the goal to accelerate the development of cures for spinal cord injuries. While many of the recommendations are framed within the context of the specific needs articulated by the New York Spinal Cord Injury Research Board, the Institute of Medicine's panel of experts looked very broadly at research priorities relating to future directions for the field in general and make recommendations to strengthen and coordinate the existing infrastructure. Funders at federal and state agencies, academic organizations, pharmaceutical and device companies, and non-profit organizations will all find this book to be an essential resource as they examine their opportunities.

Therapeutic Strategies to Spinal Cord Injury

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Author :
Publisher :
ISBN 13 : 9783038974079
Total Pages : pages
Book Rating : 4.9/5 (74 download)

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Book Synopsis Therapeutic Strategies to Spinal Cord Injury by : Pavla Jendelova

Download or read book Therapeutic Strategies to Spinal Cord Injury written by Pavla Jendelova and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue gathers eight research articles covering a broad range of strategies on how to combat spinal cord injuries, from searching for therapeutic target molecules, tackling inflammatory reactions, utilizing cell therapy or cell-based products, combined strategies for axonal plasticity assessment, and prevention of post-surgical epidural adhesions. Moreover, four reviews cover recent findings about the role of stress-activated protein kinases in SCI; progress in stem cell therapies; the mechanisms and benefits of activity-based physical rehabilitation therapies with adjuvant testosterone; and, finally, translational regenerative therapies for chronic spinal cord injury.

Mesenchymal Stem Cell Derived Exosomes

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Publisher : Academic Press
ISBN 13 : 0128004975
Total Pages : 288 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mesenchymal Stem Cell Derived Exosomes by : Yaoliang Tang

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Neural Regeneration

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Author :
Publisher : Academic Press
ISBN 13 : 0128018348
Total Pages : 444 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neural Regeneration by : Kwok Fai So

Download or read book Neural Regeneration written by Kwok Fai So and published by Academic Press. This book was released on 2015-02-03 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebrates Neural regeneration in the peripheral nervous system Neural regeneration in the central nervous system Transplantation-mediated neural regeneration Clinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research. Provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration Highly translational and clinically-relevance International authors who are leaders in their respective fields Vivid art work making the chapters easily understood