Some Mathematical Models From Population Genetics

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Some Mathematical Models from Population Genetics

Author : Alison Etheridge
Publisher : Springer Science & Business Media
ISBN 13 : 3642166318
Total Pages : 129 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Some Mathematical Models from Population Genetics by : Alison Etheridge

Download or read book Some Mathematical Models from Population Genetics written by Alison Etheridge and published by Springer Science & Business Media. This book was released on 2011-01-07 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.

Handbook of Statistical Genomics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 1119429250
Total Pages : 1828 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Handbook of Statistical Genomics by : David J. Balding

Download or read book Handbook of Statistical Genomics written by David J. Balding and published by John Wiley & Sons. This book was released on 2019-07-09 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Mathematical Topics in Population Genetics

Author : Ken-ichi Kojima
Publisher : Springer Science & Business Media
ISBN 13 : 3642462448
Total Pages : 408 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Mathematical Topics in Population Genetics by : Ken-ichi Kojima

Download or read book Mathematical Topics in Population Genetics written by Ken-ichi Kojima and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: A basic method of analyzing particulate gene systems is the proba bilistic and statistical analyses. Mendel himself could not escape from an application of elementary probability analysis although he might have been unaware of this fact. Even Galtonian geneticists in the late 1800's and the early 1900's pursued problems of heredity by means of mathe matics and mathematical statistics. They failed to find the principles of heredity, but succeeded to establish an interdisciplinary area between mathematics and biology, which we call now Biometrics, Biometry, or Applied Statistics. A monumental work in the field of popUlation genetics was published by the late R. A. Fisher, who analyzed "the correlation among relatives" based on Mendelian gene theory (1918). This theoretical analysis over came "so-called blending inheritance" theory, and the orientation of Galtonian explanations for correlations among relatives for quantitative traits rapidly changed. We must not forget the experimental works of Johanson (1909) and Nilsson-Ehle (1909) which supported Mendelian gene theory. However, a large scale experiment for a test of segregation and linkage of Mendelian genes affecting quantitative traits was, prob ably for the first time, conducted by K. Mather and his associates and Panse in the 1940's.

From Genetics to Mathematics

Author : Miroslaw Lachowicz
Publisher : World Scientific
ISBN 13 : 9812837256
Total Pages : 242 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis From Genetics to Mathematics by : Miroslaw Lachowicz

Download or read book From Genetics to Mathematics written by Miroslaw Lachowicz and published by World Scientific. This book was released on 2009 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains pedagogical and elementary introductions to genetics for mathematicians and physicists as well as to mathematical models and techniques of population dynamics. It also offers a physicist''s perspective on modeling biological processes. Each chapter starts with an overview followed by the recent results obtained by authors. Lectures are self-contained and are devoted to various phenomena such as the evolution of the genetic code and genomes, age-structured populations, demography, sympatric speciation, the Penna model, Lotka-Volterra and other predator-prey models, evolutionary models of ecosystems, extinctions of species, and the origin and development of language. Authors analyze their models from the computational and mathematical points of view.

Some Mathematical Questions in Biology

Author : Alan Hastings
Publisher : American Mathematical Soc.
ISBN 13 : 9780821897157
Total Pages : 136 pages
Book Rating : 4.8/5 (971 download)

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Book Synopsis Some Mathematical Questions in Biology by : Alan Hastings

Download or read book Some Mathematical Questions in Biology written by Alan Hastings and published by American Mathematical Soc.. This book was released on 1989-12-31 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Population biology has had a long history of mathematical modeling. The 1920s and 1930s saw major strides with the work of Lotka and Volterra in ecology and Fisher, Haldane, and Wright in genetics. In recent years, much more sophisticated mathematical techniques have been brought to bear on questions in population biology. Simultaneously, advances in experimental and field work have produced a wealth of new data. While this growth has tended to fragment the field, one unifying theme is that similar mathematical questions arise in a range of biological contexts. This volume contains the proceedings of a symposium on Some Mathematical Questions in Biology, held in Chicago in 1987. The papers all deal with different aspects of population biology, but there are overlaps in the mathematical techniques used; for example, dynamics of nonlinear differential and difference equations form a common theme. The topics covered are cultural evolution, multilocus population genetics, spatially structured population genetics, chaos and the dynamics of epidemics, and the dynamics of ecological communities.

Mathematics of Genetic Diversity

Author : J. F. C. Kingman
Publisher : SIAM
ISBN 13 : 9781611970357
Total Pages : 77 pages
Book Rating : 4.9/5 (73 download)

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Book Synopsis Mathematics of Genetic Diversity by : J. F. C. Kingman

Download or read book Mathematics of Genetic Diversity written by J. F. C. Kingman and published by SIAM. This book was released on 1980-01-01 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together some mathematical ideas that are useful in population genetics, concentrating on a few aspects which are both biologically relevant and mathematically interesting.

Mathematical Population Genetics 1

Author : Warren J. Ewens
Publisher : Springer Science & Business Media
ISBN 13 : 038721822X
Total Pages : 435 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Mathematical Population Genetics 1 by : Warren J. Ewens

Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Foundations of Mathematical Genetics

Author : Anthony William Fairbank Edwards
Publisher : Cambridge University Press
ISBN 13 : 9780521775441
Total Pages : 138 pages
Book Rating : 4.7/5 (754 download)

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Book Synopsis Foundations of Mathematical Genetics by : Anthony William Fairbank Edwards

Download or read book Foundations of Mathematical Genetics written by Anthony William Fairbank Edwards and published by Cambridge University Press. This book was released on 2000-01-13 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive account of the origins of modern mathematical population genetics, first published in 2000.

Introduction to Theoretical Population Genetics

Author : Thomas Nagylaki
Publisher : Springer Science & Business Media
ISBN 13 : 364276214X
Total Pages : 381 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Introduction to Theoretical Population Genetics by : Thomas Nagylaki

Download or read book Introduction to Theoretical Population Genetics written by Thomas Nagylaki and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).

Nonlinear PDEs

Author : Marius Ghergu
Publisher : Springer Science & Business Media
ISBN 13 : 3642226647
Total Pages : 394 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Nonlinear PDEs by : Marius Ghergu

Download or read book Nonlinear PDEs written by Marius Ghergu and published by Springer Science & Business Media. This book was released on 2011-10-22 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis throughout the present volume is on the practical application of theoretical mathematical models helping to unravel the underlying mechanisms involved in processes from mathematical physics and biosciences. It has been conceived as a unique collection of abstract methods dealing especially with nonlinear partial differential equations (either stationary or evolutionary) that are applied to understand concrete processes involving some important applications related to phenomena such as: boundary layer phenomena for viscous fluids, population dynamics,, dead core phenomena, etc. It addresses researchers and post-graduate students working at the interplay between mathematics and other fields of science and technology and is a comprehensive introduction to the theory of nonlinear partial differential equations and its main principles also presents their real-life applications in various contexts: mathematical physics, chemistry, mathematical biology, and population genetics. Based on the authors' original work, this volume provides an overview of the field, with examples suitable for researchers but also for graduate students entering research. The method of presentation appeals to readers with diverse backgrounds in partial differential equations and functional analysis. Each chapter includes detailed heuristic arguments, providing thorough motivation for the material developed later in the text. The content demonstrates in a firm way that partial differential equations can be used to address a large variety of phenomena occurring in and influencing our daily lives. The extensive reference list and index make this book a valuable resource for researchers working in a variety of fields and who are interested in phenomena modeled by nonlinear partial differential equations.

Mathematical Population Genetics

Author : Warren J. Ewens
Publisher :
ISBN 13 :
Total Pages : 325 pages
Book Rating : 4.:/5 (79 download)

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Book Synopsis Mathematical Population Genetics by : Warren J. Ewens

Download or read book Mathematical Population Genetics written by Warren J. Ewens and published by . This book was released on 1979 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mathematical Structures in Population Genetics

Author : I︠U︡riĭ Ilʹich Li︠u︡bich
Publisher : Springer
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Mathematical Structures in Population Genetics by : I︠U︡riĭ Ilʹich Li︠u︡bich

Download or read book Mathematical Structures in Population Genetics written by I︠U︡riĭ Ilʹich Li︠u︡bich and published by Springer. This book was released on 1992-03-16 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Very Good,No Highlights or Markup,all pages are intact.

Mathematical Structures in Population Genetics

Author : Yuri I. Lyubich
Publisher : Springer
ISBN 13 : 9783642762116
Total Pages : 0 pages
Book Rating : 4.7/5 (621 download)

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Book Synopsis Mathematical Structures in Population Genetics by : Yuri I. Lyubich

Download or read book Mathematical Structures in Population Genetics written by Yuri I. Lyubich and published by Springer. This book was released on 1992 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical methods have been applied successfully to population genet ics for a long time. Even the quite elementary ideas used initially proved amazingly effective. For example, the famous Hardy-Weinberg Law (1908) is basic to many calculations in population genetics. The mathematics in the classical works of Fisher, Haldane and Wright was also not very complicated but was of great help for the theoretical understanding of evolutionary pro cesses. More recently, the methods of mathematical genetics have become more sophisticated. In use are probability theory, stochastic processes, non linear differential and difference equations and nonassociative algebras. First contacts with topology have been established. Now in addition to the tra ditional movement of mathematics for genetics, inspiration is flowing in the opposite direction, yielding mathematics from genetics. The present mono grapll reflects to some degree both patterns but especially the latter one. A pioneer of this synthesis was S. N. Bernstein. He raised-and partially solved- -the problem of characterizing all stationary evolutionary operators, and this work was continued by the author in a series of papers (1971-1979). This problem has not been completely solved, but it appears that only cer tain operators devoid of any biological significance remain to be addressed. The results of these studies appear in chapters 4 and 5. The necessary alge braic preliminaries are described in chapter 3 after some elementary models in chapter 2.

Understanding Population Genetics

Author : Torbjörn Säll
Publisher : John Wiley & Sons
ISBN 13 : 1119124077
Total Pages : 280 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Understanding Population Genetics by : Torbjörn Säll

Download or read book Understanding Population Genetics written by Torbjörn Säll and published by John Wiley & Sons. This book was released on 2017-07-14 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life – in all its improbable and amazing richness – one must start by understanding population genetics.

Information Geometry and Population Genetics

Author : Julian Hofrichter
Publisher : Springer
ISBN 13 : 3319520458
Total Pages : 320 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Information Geometry and Population Genetics by : Julian Hofrichter

Download or read book Information Geometry and Population Genetics written by Julian Hofrichter and published by Springer. This book was released on 2017-02-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.

Mathematical Population Genetics

Author : W. J. Ewens
Publisher : Springer
ISBN 13 :
Total Pages : 354 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Mathematical Population Genetics by : W. J. Ewens

Download or read book Mathematical Population Genetics written by W. J. Ewens and published by Springer. This book was released on 1979-11 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mathematical Population Genetics 1

Author : Warren J. Ewens
Publisher : Springer
ISBN 13 : 9781468495881
Total Pages : 418 pages
Book Rating : 4.4/5 (958 download)

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Book Synopsis Mathematical Population Genetics 1 by : Warren J. Ewens

Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer. This book was released on 2012-11-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.