Sodium Channels, Pain, and Analgesia (2005).

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (785 download)

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Download or read book Sodium Channels, Pain, and Analgesia (2005). written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sodium Channels, Pain, and Analgesia

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 376437411X
Total Pages : 204 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Sodium Channels, Pain, and Analgesia by : Kevin Coward

Download or read book Sodium Channels, Pain, and Analgesia written by Kevin Coward and published by Springer Science & Business Media. This book was released on 2006-01-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme. Authors from the pharmaceutical industry discuss pharmacological approaches to the drug targeting of sodium channels, and in particular Nav1.8, exclusively expressed in nociceptive neurons. The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology.

The Essence of Analgesia and Analgesics

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Publisher : Cambridge University Press
ISBN 13 : 1139491989
Total Pages : 551 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Essence of Analgesia and Analgesics by : Raymond S. Sinatra

Download or read book The Essence of Analgesia and Analgesics written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2010-10-14 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Pain Management and the Opioid Epidemic

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Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Acute Pain Management

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Publisher : Cambridge University Press
ISBN 13 : 0521874912
Total Pages : 729 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Acute Pain Management by : Raymond S. Sinatra

Download or read book Acute Pain Management written by Raymond S. Sinatra and published by Cambridge University Press. This book was released on 2009-04-27 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.

Ion Channels

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Publisher : Humana Press
ISBN 13 : 9781493960095
Total Pages : 456 pages
Book Rating : 4.9/5 (6 download)

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Book Synopsis Ion Channels by : Nikita Gamper

Download or read book Ion Channels written by Nikita Gamper and published by Humana Press. This book was released on 2016-05-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Methods in Molecular Biology book offers strategies and protocols for studying a large group of proteins that form ionic channels in the plasma membrane and intracellular membranes of cells. Includes step-by-step protocols, materials lists, tips and more."

Mechanisms of Vascular Disease

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Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Voltage Gated Sodium Channels

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Publisher : Springer Science & Business Media
ISBN 13 : 3642415881
Total Pages : 328 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Voltage Gated Sodium Channels by : Peter C. Ruben

Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Magnesium in the Central Nervous System

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Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Chronic Postsurgical Pain

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Publisher : Springer Science & Business Media
ISBN 13 : 3319043226
Total Pages : 175 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Chronic Postsurgical Pain by : Gérard Mick

Download or read book Chronic Postsurgical Pain written by Gérard Mick and published by Springer Science & Business Media. This book was released on 2014-02-20 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

Pharmacology of Pain

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331915
Total Pages : 978 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pharmacology of Pain by : Pierre Beaulieu

Download or read book Pharmacology of Pain written by Pierre Beaulieu and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain. Who should buy this book? Pharmacology of Pain is a particularly useful resource for: Basic researchers and clinicians, including physicians, dentists, pharmacists, nurses, and physical therapists Other professionals in the field of pain research and treatment Students and trainees

Oxford Textbook of Palliative Medicine

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Publisher : Oxford University Press, USA
ISBN 13 : 0199656096
Total Pages : 1281 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Palliative Medicine by : Nathan I. Cherny

Download or read book Oxford Textbook of Palliative Medicine written by Nathan I. Cherny and published by Oxford University Press, USA. This book was released on 2015 with total page 1281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasising the multi-disciplinary nature of palliative care the fourth edition of this text also looks at the individual professional roles that contribute to the best-quality palliative care.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

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Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Veterinary Anesthesia and Analgesia

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Publisher : John Wiley & Sons
ISBN 13 : 1118526236
Total Pages : 1072 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Veterinary Anesthesia and Analgesia by : Kurt A. Grimm

Download or read book Veterinary Anesthesia and Analgesia written by Kurt A. Grimm and published by John Wiley & Sons. This book was released on 2015-05-11 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images

Pain Models

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331931
Total Pages : 663 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pain Models by : Hermann O. Handwerker

Download or read book Pain Models written by Hermann O. Handwerker and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model.

Pain Relief

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Publisher : BoD – Books on Demand
ISBN 13 : 9535131877
Total Pages : 364 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Pain Relief by : Cecilia Maldonado

Download or read book Pain Relief written by Cecilia Maldonado and published by BoD – Books on Demand. This book was released on 2017-05-24 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the beginning of times, pain treatment has been the motive of research giving birth to multiple groups of pharmacological families and therapies. Pain perception is a construction built over the biological phenomenon of signal transduction surrounded by different factors such as gender, age, and sociocultural status, among others. The concept of pain as the solely biological manifestation of defense is nowadays considered as a narrow-minded view of this topic. In this regard concepts such as newborns feel no pain or older people complain about everything therefore should not be paid attention when referring pain, are being left behind in the understanding that pain alleviation is a human right and everybody feeling pain should be helped for its relief. This book comprises many aspects of pain treatment and the drugs involved in it. From old analgesics with new mechanisms of action for pain alleviation to analgesics potential for diminishing oxidative stress; from pharmacological therapies to electrical ones, going through alternative medicine; and from pain treatment in dentistry to chronic pain therapies, also boarding the treatment of migraine, different experts share their knowledge on the topic.

Acute Pain Management

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Publisher :
ISBN 13 : 9780977517442
Total Pages : 491 pages
Book Rating : 4.5/5 (174 download)

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Book Synopsis Acute Pain Management by : Pamela E. Macintyre

Download or read book Acute Pain Management written by Pamela E. Macintyre and published by . This book was released on 2010-01-01 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: