RNA Chaperones

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Publisher :
ISBN 13 : 9781071602317
Total Pages : 314 pages
Book Rating : 4.6/5 (23 download)

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Book Synopsis RNA Chaperones by : Tilman Heise

Download or read book RNA Chaperones written by Tilman Heise and published by . This book was released on 2020 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a wide spectrum of methods to study RNA chaperones in vitro, at the single molecule level, and protocols useful for cell-based assays. Beginning with a section on a number of bacterial proteins for study, the volume also explores proteins from eukaryotic cells and how to delve into the complex interactions between RNA chaperones and the folding and unfolding of proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Chaperones: Methods and Protocols serves as an ideal guide for scientists and students interested in RNA biology and RNA chaperones. Chapter 3 is available Open Access under a CC-BY 4.0 license via link.springer.com.

Mechanisms of Transcription

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Publisher : CSHL Press
ISBN 13 : 9780879695507
Total Pages : 724 pages
Book Rating : 4.6/5 (955 download)

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Book Synopsis Mechanisms of Transcription by : Bruce Stillman

Download or read book Mechanisms of Transcription written by Bruce Stillman and published by CSHL Press. This book was released on 1998 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a summer 1998 meeting, presenting results of recent studies in gene transcription. Covers events ranging from activation, through promoter recognition, repression, chromosome structure, chromatin remodeling, initiation and elongation, and regulatory complexes and pathways. Subjects include targeting sir proteins to sites of action, the yeast RNA polymerase III transcription machinery, nuclear matrix attachment regions to confer long-range function on immunoglobulin, ATP-dependent remodeling of chromatin, and the transcriptional basis of steroid physiology. Annotation copyrighted by Book News, Inc., Portland, OR.

Integrating Timescales from Molecules Up

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Publisher : Frontiers Media SA
ISBN 13 : 2889668606
Total Pages : 83 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Integrating Timescales from Molecules Up by : Rene A. Nome

Download or read book Integrating Timescales from Molecules Up written by Rene A. Nome and published by Frontiers Media SA. This book was released on 2021-06-04 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA Folding

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Publisher : Humana
ISBN 13 : 9781493960583
Total Pages : 0 pages
Book Rating : 4.9/5 (65 download)

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Book Synopsis RNA Folding by : Christina Waldsich

Download or read book RNA Folding written by Christina Waldsich and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on in vitro and intracellular RNA structure formation, RNA Folding: Methods and Protocols provides a comprehensive collection of experimental protocols which are suitable to dissect RNA folding pathways and to characterize the structure of RNA folding intermediates at nucleotide or even atomic resolution. The presented techniques include powerful tools with a long tradition in RNA research as well as more advanced, novel methods, thus the methods span multiple disciplines, including molecular biology, biochemistry, biophysics, and computational biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, RNA Folding: Methods and Protocols serves as a vital reference for researchers attempting to gain insights into the secrets of this astounding macromolecule.

Structures of Large RNA Molecules and Their Complexes

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Publisher : Academic Press
ISBN 13 : 0128019360
Total Pages : 675 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Structures of Large RNA Molecules and Their Complexes by :

Download or read book Structures of Large RNA Molecules and Their Complexes written by and published by Academic Press. This book was released on 2015-06-06 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in RNA folding and dynamics, RNA-protein interactions and large RNPs. - Continues the legacy of this premier serial with quality chapters on structures of large RNA molecules and their complexes

Biophysics of Infection

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Publisher : Springer
ISBN 13 : 3319321897
Total Pages : 364 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Biophysics of Infection by : Mark C. Leake

Download or read book Biophysics of Infection written by Mark C. Leake and published by Springer. This book was released on 2016-05-18 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.

In-cell NMR Spectroscopy

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839160934
Total Pages : 322 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis In-cell NMR Spectroscopy by : Yutaka Ito

Download or read book In-cell NMR Spectroscopy written by Yutaka Ito and published by Royal Society of Chemistry. This book was released on 2019-12-09 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.

RNA Nanotechnology

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Publisher : CRC Press
ISBN 13 : 9814411647
Total Pages : 468 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis RNA Nanotechnology by : Bin Wang

Download or read book RNA Nanotechnology written by Bin Wang and published by CRC Press. This book was released on 2014-04-02 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals. The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.

Artificial Riboswitches

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Publisher : Humana
ISBN 13 : 9781493963300
Total Pages : 0 pages
Book Rating : 4.9/5 (633 download)

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Book Synopsis Artificial Riboswitches by : Atsushi Ogawa

Download or read book Artificial Riboswitches written by Atsushi Ogawa and published by Humana. This book was released on 2016-09-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial riboswitches and other ligand-responsive gene regulators make it possible to switch protein synthesis ON or OFF with arbitrary ligand molecules. Artificial Riboswitches: Methods and Protocols focuses on the state-of-the-art methods developed in recent years for creating artificial riboswitches, therefore this volume could be regarded as a collection of recipes for the gene circuit elements in synthetic biology and metabolic engineering. Chapters cover topics such as screening or rational design methods for obtaining artificial riboswitches that function in either bacterial or eukaryotic translational systems, protocols for evaluating the activities of the resultant riboswitches, as well as protocols for construction of ligand-dependent, trans-acting gene regulators. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Artificial Riboswitches: Methods and Protocols seeks to serve not only bioengineers who aim to reprogram cell behaviors and molecular biologists who leverage these regulators for genetic studies, but to all researchers interested in this fascinating field.

Biophysics of RNA-Protein Interactions

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Publisher : Springer Nature
ISBN 13 : 1493997262
Total Pages : 249 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Biophysics of RNA-Protein Interactions by : Chirlmin Joo

Download or read book Biophysics of RNA-Protein Interactions written by Chirlmin Joo and published by Springer Nature. This book was released on 2019-09-19 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more. The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.

Recoding: Expansion of Decoding Rules Enriches Gene Expression

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Publisher : Springer Science & Business Media
ISBN 13 : 0387893822
Total Pages : 473 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Recoding: Expansion of Decoding Rules Enriches Gene Expression by : John F. Atkins

Download or read book Recoding: Expansion of Decoding Rules Enriches Gene Expression written by John F. Atkins and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Riboswitch Discovery, Structure and Function

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Publisher : Academic Press
ISBN 13 : 0128013354
Total Pages : 595 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Riboswitch Discovery, Structure and Function by :

Download or read book Riboswitch Discovery, Structure and Function written by and published by Academic Press. This book was released on 2014-11-21 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in riboswitch discovery and validation, synthesis and sample prep methods for large RNAs, riboswitch structure and function methods, folding pathways and dynamics, and ligand interactions and thermodynamics. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in riboswitch discovery, structure and function - Contains sections on such topics as riboswitch discovery and validation, synthesis and sample prep methods for large RNAs, riboswitch structure and function methods, folding pathways and dynamics, ligand interactions and thermodynamics

Computational Methods for Understanding Riboswitches

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Publisher : Academic Press
ISBN 13 : 0128016183
Total Pages : 449 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Computational Methods for Understanding Riboswitches by :

Download or read book Computational Methods for Understanding Riboswitches written by and published by Academic Press. This book was released on 2015-02-24 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers computational prediction RNA structure and dynamics, including such topics as computational modeling of RNA secondary and tertiary structures, riboswitch dynamics, and ion-RNA, ligand-RNA and DNA-RNA interactions. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers computational methods and applications in RNA structure and dynamics - Contains chapters with emerging topics such as RNA structure prediction, riboswitch dynamics and thermodynamics, and effects of ions and ligands.

Isotope labeling in Biomolecular NMR

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Publisher : Springer Science & Business Media
ISBN 13 : 9400749546
Total Pages : 219 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Isotope labeling in Biomolecular NMR by : Hanudatta S. Atreya

Download or read book Isotope labeling in Biomolecular NMR written by Hanudatta S. Atreya and published by Springer Science & Business Media. This book was released on 2012-10-18 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Nucleic Acids

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Publisher : Sterling Publishing Company
ISBN 13 : 9780935702491
Total Pages : 854 pages
Book Rating : 4.7/5 (24 download)

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Book Synopsis Nucleic Acids by : Victor A. Bloomfield

Download or read book Nucleic Acids written by Victor A. Bloomfield and published by Sterling Publishing Company. This book was released on 2000-04-17 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.

Nanotechnology Tools for the Study of RNA

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Publisher : Academic Press
ISBN 13 : 0128045744
Total Pages : 242 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanotechnology Tools for the Study of RNA by :

Download or read book Nanotechnology Tools for the Study of RNA written by and published by Academic Press. This book was released on 2016-02-23 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Molecular Biology and Translational Science introduces emerging strategies of studying RNA structure and function using nanotechnological tools. The volume aims to provide the readers with a novel view and give them opportunities to think about how to incorporate the new technologies into their own research. - This book informs and updates on strategies to take advantages of nanotechnological tools to answer to fundamental questions in RNA science - Collection of reviews written by the leading scientists from the field - The book covers a range of topics, from single molecule analyses using nanomaterials to gene regulation using RNA nanostructures

Simulation Algorithms for Computational Systems Biology

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Publisher : Springer
ISBN 13 : 3319631136
Total Pages : 245 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Simulation Algorithms for Computational Systems Biology by : Luca Marchetti

Download or read book Simulation Algorithms for Computational Systems Biology written by Luca Marchetti and published by Springer. This book was released on 2017-09-27 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies. This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.