Recoding Expansion Of Decoding Rules Enriches Gene Expression

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Recoding: Expansion of Decoding Rules Enriches Gene Expression

Author : John F. Atkins
Publisher : Springer Science & Business Media
ISBN 13 : 0387893822
Total Pages : 473 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Recoding: Expansion of Decoding Rules Enriches Gene Expression by : John F. Atkins

Download or read book Recoding: Expansion of Decoding Rules Enriches Gene Expression written by John F. Atkins and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Recoding: Expansion of Decoding Rules Enriches Gene Expression

Author : John F. Atkins
Publisher : Springer
ISBN 13 : 9780387893815
Total Pages : 466 pages
Book Rating : 4.8/5 (938 download)

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Book Synopsis Recoding: Expansion of Decoding Rules Enriches Gene Expression by : John F. Atkins

Download or read book Recoding: Expansion of Decoding Rules Enriches Gene Expression written by John F. Atkins and published by Springer. This book was released on 2009-12-16 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Recoding

Author : John F. Atkins
Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.:/5 (935 download)

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Book Synopsis Recoding by : John F. Atkins

Download or read book Recoding written by John F. Atkins and published by . This book was released on 2010 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic code is dynamic - it, or its readout, can be specifically changed by mRNA signals that modify the behavior of on-board ribosomes. This book describes specific recoding examples to understand the mechanisms and the mRNA signals.

Frontiers in Clinical Drug Research: HIV

Author : Atta-ur-Rahman
Publisher : Bentham Science Publishers
ISBN 13 : 1608058964
Total Pages : 300 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Frontiers in Clinical Drug Research: HIV by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research: HIV written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2015-04-02 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – HIV is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the eBook series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research. The first volume of this series features 7 chapters that cover a variety of topics including: -Antiretroviral drug development -HIV-1 genomics -HIV drug targets such as ribosomes and HIV Integrase -HAART associated nephrotoxicity

Innovations in Biotechnology

Author : Eddy C. Agbo
Publisher : BoD – Books on Demand
ISBN 13 : 9535100963
Total Pages : 478 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Innovations in Biotechnology by : Eddy C. Agbo

Download or read book Innovations in Biotechnology written by Eddy C. Agbo and published by BoD – Books on Demand. This book was released on 2012-02-17 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innovations in Biotechnology provides an authoritative crystallization of some of the evolving leading-edge biomedical research topics and developments in the field of biotechnology. It is aptly written to integrate emerging basic research topics with their biotechnology applications. It also challenges the reader to appreciate the role of biotechnology in society, addressing clear questions relating to biotech policy and ethics in the context of the research advances. In an era of interdisciplinary collaboration, the book serves an excellent indepth text for a broad range of readers ranging from social scientists to students, researchers and policy makers. Every topic weaves back to the same bottom line: how does this discovery impact society in a positive way?

mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation

Author : Daniel L. Kiss
Publisher : Frontiers Media SA
ISBN 13 : 2889765903
Total Pages : 135 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation by : Daniel L. Kiss

Download or read book mRNA Translational Control as a Mechanism of Post-transcriptional Gene Regulation written by Daniel L. Kiss and published by Frontiers Media SA. This book was released on 2022-07-25 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Relevance of Translational Regulation on Plant Growth and Environmental Responses

Author : Alejandro Ferrando
Publisher : Frontiers Media SA
ISBN 13 : 2889454134
Total Pages : 138 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Relevance of Translational Regulation on Plant Growth and Environmental Responses by : Alejandro Ferrando

Download or read book Relevance of Translational Regulation on Plant Growth and Environmental Responses written by Alejandro Ferrando and published by Frontiers Media SA. This book was released on 2018-02-19 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, as sessile organisms, are exposed to a large array of challenging external and internal alterations that may restrict plant growth. These limiting growth conditions activate plant signalling responses which eventually target the protein synthesis machinery to rapidly reprogram plant metabolism to adapt to the new situation. Thus, the control of mRNA translation is one key regulatory step of gene expression and it is an essential molecular mechanism used by plants to bring about impressive growth plasticity. Compared to the vast number of studies aimed to identify plant transcriptional changes upon hormonal or environmental cues, the subsequent steps of mRNA transport, stability, storage, and eventually translational regulation, have been less studied in plants. This lack of knowledge concerns not only the fate of protein-coding transcripts in plants, but also the biogenesis and maturation of rRNAs, tRNAs and the plant translation factors involved. In this eBook we have focused on how internal cues and external signals of either biotic or abiotic origin impact translation to adjust plant growth and development. We have collected altogether ten scientific contributions to extend the knowledge on plant post-transcriptional and translational events that regulate the production of proteins that execute the required cellular functions. We hope that this compilation of original research articles and reviews will provide the readers with a detailed update on the state of knowledge in this field, and also with additional motivation to improve plant growth adaptation to future environmental challenges.

Archaeal Ribosomes: Biogenesis, Structure and Function

Author : Paola Londei
Publisher : Frontiers Media SA
ISBN 13 : 2889741419
Total Pages : 164 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Archaeal Ribosomes: Biogenesis, Structure and Function by : Paola Londei

Download or read book Archaeal Ribosomes: Biogenesis, Structure and Function written by Paola Londei and published by Frontiers Media SA. This book was released on 2022-01-24 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fidelity and Quality Control in Gene Expression

Author : Assen Marintchev
Publisher : Academic Press
ISBN 13 : 0123864976
Total Pages : 267 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Fidelity and Quality Control in Gene Expression by : Assen Marintchev

Download or read book Fidelity and Quality Control in Gene Expression written by Assen Marintchev and published by Academic Press. This book was released on 2012-01-27 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting. Provides a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation Special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting

Short Views on Insect Genomics and Proteomics

Author : Chandrasekar Raman
Publisher : Springer
ISBN 13 : 331924244X
Total Pages : 251 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Short Views on Insect Genomics and Proteomics by : Chandrasekar Raman

Download or read book Short Views on Insect Genomics and Proteomics written by Chandrasekar Raman and published by Springer. This book was released on 2015-12-10 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entomology is a super science, embracing interdisciplinary approaches in genomics, proteomics, and interdependent fields of biochemistry, physiology, molecular entomology, and biotechnology. An urgent need to manage available resources for the benefit of the planet and humankind has led to remarkable progress since publication of the fruit fly genome in 2000. “Short Views on Insect Genomics and Proteomics” presents multiple perspectives of recognized experts from around the world in genomics, bioinformatics, molecular biology, biochemistry, physiology, and immunology, emphasizing fast-moving areas of current research on insects and other arthropods. Concise, accessible, topical reviews include body lice and white fly genome projects, aphid phenotypic plasticity, insect regulatory genomics, the complex tick sialome, protein expression systems, therapeutic potential of insect antimicrobial peptides, nanoparticle insecticides, and novel uses for recombinant and synthetic spider silks.

Prokaryotic Systems Biology

Author : Nevan J. Krogan, PhD
Publisher : Springer
ISBN 13 : 3319236032
Total Pages : 319 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Prokaryotic Systems Biology by : Nevan J. Krogan, PhD

Download or read book Prokaryotic Systems Biology written by Nevan J. Krogan, PhD and published by Springer. This book was released on 2015-11-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species. The first part of the volume consists of nine chapters, focusing on biochemical and genetics and genomics approaches including yeast two hybrid, metagenomics, affinity purification in combination with mass spectrometry, chromatin-immunoprecipitation coupled with sequencing, large-scale synthetic genetic screens, and quantitative-based mass spectrometry strategies for mapping the bacterial physical, functional, substrate, and regulatory interaction networks needed for interpreting biological networks, inferring gene function, enzyme discovery, and identifying new drug targets. The second part comprises five chapters, covering the network of participants for protein folding and complex enzyme maturation. It also covers the structural approaches required to understand bacterial intramembrane proteolysis and the structure and function of bacterial proteins involved in surface polysaccharides, outer membrane, and envelope assembly. This volume concludes with a focus on computational and comparative genomics approaches, especially network-based methods for predicting physical or functional interactions, and integrative analytical approaches for generating more reliable information on bacterial gene function. This book provides foundational knowledge in the understanding of prokaryotic systems biology by illuminating how bacterial genes f unction within the framework of global cellular processes. The book will enable the microbiology community to create substantive resources for addressing many pending unanswered questions, and facilitate the development of new technologies that can be applied to other bacterial species lacking experimental data.

The Lure of Bacterial Genetics

Author : Stanley Maloy
Publisher : American Society for Microbiology Press
ISBN 13 : 1555815383
Total Pages : 557 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis The Lure of Bacterial Genetics by : Stanley Maloy

Download or read book The Lure of Bacterial Genetics written by Stanley Maloy and published by American Society for Microbiology Press. This book was released on 2010-11-01 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique, rigorous scientific approach to understanding bacterial genetics • Provides a complete overview of the entire field of bacterial genetics, helping the reader to understand how the field has evolved. • Inspires readers by providing an opportunity to learn from John Roth’s achievements and contributions to bacterial genetics. • Offers valuable lessons in the history and science of bacterial genetics by providing a behind the scenes look at some of the most important triumphs and mishaps that have occurred on the path to discovery.

Mobile DNA III

Author : Michael Chandler
Publisher : John Wiley & Sons
ISBN 13 : 1555819214
Total Pages : 1321 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Mobile DNA III by : Michael Chandler

Download or read book Mobile DNA III written by Michael Chandler and published by John Wiley & Sons. This book was released on 2020-07-24 with total page 1321 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.

Brenner's Encyclopedia of Genetics

Author : Stanley Maloy
Publisher : Academic Press
ISBN 13 : 0080961568
Total Pages : 4360 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Brenner's Encyclopedia of Genetics by : Stanley Maloy

Download or read book Brenner's Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

Pattern Recognition in Bioinformatics

Author : Matteo Comin
Publisher : Springer
ISBN 13 : 3319091921
Total Pages : 135 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Pattern Recognition in Bioinformatics by : Matteo Comin

Download or read book Pattern Recognition in Bioinformatics written by Matteo Comin and published by Springer. This book was released on 2014-08-13 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 8th IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2014, held in Stockholm, Sweden in August 2014. The 9 revised full papers and 9 revised short papers presented were carefully reviewed and selected from 29 submissions. The focus of the conference was on the latest Research in Pattern Recognition and Computational Intelligence-Based Techniques Applied to Problems in Bioinformatics and Computational Biology.

Fish Physiology: Organic Chemical Toxicology of Fishes

Author : Keith B. Tierney
Publisher : Academic Press
ISBN 13 : 0123982553
Total Pages : 574 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Fish Physiology: Organic Chemical Toxicology of Fishes by : Keith B. Tierney

Download or read book Fish Physiology: Organic Chemical Toxicology of Fishes written by Keith B. Tierney and published by Academic Press. This book was released on 2013-12-04 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish. The book also covers the detection of dissolved organic compounds and methods to assess organic toxicity. Substances addressed in this book include organometallics, hydrocarbons, endocrine disrupting compounds (EDCs), insecticides, herbicides, and pharmaceuticals. Fish are exposed to an ever-increasing array of organic chemicals that find their way into rivers and oceans. Some of these compounds are no longer being produced but nonetheless persist within the environment (persistent organic pollutants, or POPs). The exposure of fish to toxic organic compounds has potential impact on human, fish, and ecosystem health. Yet the regulations that govern environmental water quality vary worldwide, and compliance is never complete. This book provides a crucial resource on these issues for researchers in zoology, fish physiology, and related fields; applied researchers in environmental monitoring, conservation biology, and toxicology; and university-level students and instructors in these areas. Organized by type of toxic organic chemicals Includes metals, POPs, EDCs, herbicides, insecticides, and pharmaceuticals Measures toxicity in a variety of ways aside from lethality Probes the toxic effects of compound mixtures as well as single pollutants

Homeostasis and Toxicology of Essential Metals

Author : Chris M. Wood
Publisher : Academic Press
ISBN 13 : 0123786363
Total Pages : 524 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Homeostasis and Toxicology of Essential Metals by : Chris M. Wood

Download or read book Homeostasis and Toxicology of Essential Metals written by Chris M. Wood and published by Academic Press. This book was released on 2012 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostasis and Toxicology of Essential Metals synthesizes the explosion of new information on the molecular, cellular, and organismal handling of metals in fish in the past 15 years. These elements are no longer viewed by fish physiologists as "heavy metals" that kill fish by suffocation, but rather as interesting moieties that enter and leave fish by specific pathways, which are subject to physiological regulation. The metals featured in this volume are those about which there has been most public and scientific concern, and therefore are those most widely studied by fish researchers. Metals such as Cu, Zn, Fe, Ni, Co, Se, Mo and Cr are either proven to be or are strongly suspected to be essential in trace amounts, yet are toxic in higher doses.