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Atkinsons Principles Of Clinical Pharmacology
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Book Synopsis Atkinson's Principles of Clinical Pharmacology by : Shiew-Mei Huang
Download or read book Atkinson's Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2021-10-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Book Synopsis Principles of Clinical Pharmacology by : Arthur J. Atkinson, Jr.
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson, Jr. and published by Elsevier. This book was released on 2011-04-28 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products
Book Synopsis Principles of Clinical Pharmacology by : Arthur J. Atkinson, Jr.
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson, Jr. and published by Academic Press. This book was released on 2012-09-18 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III
Book Synopsis Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition by : Johan Gabrielsson
Download or read book Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition written by Johan Gabrielsson and published by CRC Press. This book was released on 2001-11-30 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.
Book Synopsis Pharmacology and Therapeutics by : Scott A. Waldman
Download or read book Pharmacology and Therapeutics written by Scott A. Waldman and published by Saunders. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everything you need to know about all of today's drugs in a coherent, easy-to-use format - from the underlying science through innovation, translation, regulation, and clinical implementation. This multimedia resource fills a critical need for a more clinically focused, user-friendly pharmacology reference. Evidence-based therapeutic guidelines facilitate decision making; and coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine keeps you at the forefront of the latest developments.
Book Synopsis Geriatric Pharmacology by : Steven Atkinson
Download or read book Geriatric Pharmacology written by Steven Atkinson and published by . This book was released on 2016-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Geriatric Pharmacology: The Principles of Practice & Clinical Recommendations is the optimal guide for anyone seeking straightforward, concise and user-friendly information on medication dynamics for older adults. Fully revised and updated, this invaluable resource has become the go-to favorite for healthcare professionals. Here's what you'll find: Learn to manage medication combinations without causing harm How to safely prescribe opioids Avoiding the top 10 most dangerous geriatric drugs Practical guidelines to stop and start prescriptions Drug-drug interaction charts and strategies
Book Synopsis Basic Pharmacokinetics and Pharmacodynamics by : Sara E. Rosenbaum
Download or read book Basic Pharmacokinetics and Pharmacodynamics written by Sara E. Rosenbaum and published by John Wiley & Sons. This book was released on 2016-11-22 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)
Book Synopsis Brunnstrom's Clinical Kinesiology by : Peggy A Houglum
Download or read book Brunnstrom's Clinical Kinesiology written by Peggy A Houglum and published by F.A. Davis. This book was released on 2011-12-07 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now celebrating its 50 years in print, this text has held onto the foundation of its great success, while also being re-invented for today’s audience. The focus of this text remains the practical instruction of functional anatomy in order to quickly, and convincingly, guide readers to its use in professional performance. This text is filled with modern applications that will show your students the relevance of foundational material to their future careers.
Author :Stephen C. Piscitelli Publisher :Springer Science & Business Media ISBN 13 :9781617792137 Total Pages :692 pages Book Rating :4.7/5 (921 download)
Book Synopsis Drug Interactions in Infectious Diseases by : Stephen C. Piscitelli
Download or read book Drug Interactions in Infectious Diseases written by Stephen C. Piscitelli and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development
Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin
Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government
Book Synopsis Mechanisms of Clinical Signs - EPub3 by : Mark Dennis
Download or read book Mechanisms of Clinical Signs - EPub3 written by Mark Dennis and published by Elsevier Health Sciences. This book was released on 2016-08-31 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2016 BMA Medical Book Awards Highly Commended in the Medicine Category! What causes that condition? What does it mean? Organised by body system, Mechanisms of Clinical Signs, 2nd Edition explains the underlying mechanism and value of the clinical signs you are expected to know, and the conditions they indicate. Each chapter contains descriptions of clinical signs, a list of the conditions they are associated with (what conditions the signs indicate), an explanation of the mechanism and the ‘value’ of those signs (how reliable they are as an indication of a condition). There is a uniform set of subheadings for each sign: Description Condition/s associated with Mechanism/s Sign value The explanations for the mechanisms underlying each sign are brief but accurate and informative, and provide sufficient information for the reader to understand the mechanism: Signs are ordered alphabetically within each chapter outlining a specific body system. Extensive reference lists of up-to-date literature strengthen the authority of the content. Video and audio content presents real life evaluation scenarios of clinical signs. Clinical Pearls highlight the main signs which students and trainees should look out for to help them identify conditions with which the patients present. A Student Consult eBook is available with the purchase of a print book, and provides access to a total of 200 multiple choice questions covering the 7 body systems, to test students and trainees’ knowledge of the content. The eBook contains links to audio and video examples of particular signs which have to be heard or observed over a period of time in order to be identified correctly, e.g. Agonal respiration in Chapter 2 Respiratory Signs. New images are added to depict clinical signs where no images were present in the previous edition.
Book Synopsis Good Research Practice in Non-Clinical Pharmacology and Biomedicine by : Anton Bespalov
Download or read book Good Research Practice in Non-Clinical Pharmacology and Biomedicine written by Anton Bespalov and published by Springer Nature. This book was released on 2020-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Download or read book Pharmaceutics written by Alekha Dash and published by Elsevier. This book was released on 2023-09-13 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students. Facilitates an integrated and extensive coverage of the study of pharmaceutics due to the clear and engaging language used by the authors Includes chapter objectives and summaries to illustrate and reinforce key ideas Meets curricular guidelines for pharmaceutics and laboratory skills mandated by the Accreditation Council for Pharmacy Education (ACPE) Includes new practice questions, answers, and case studies for experiential learning
Book Synopsis MCQs in Clinical Pharmacy by : Lilian M. Azzopardi
Download or read book MCQs in Clinical Pharmacy written by Lilian M. Azzopardi and published by Pharmaceutical Press. This book was released on 2007 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: MCQs in Clinical Pharmacy is an invaluable revision aid for those preparing for multiple choice questions in clinical pharmacy.Questions in this textbook are practice-oriented and are intended to assess students' knowledge of clinical issues, evaluative and analytical skills, and ability to apply their knowledge in clinical practice. Topics covered include:* Therapeutics and rational drug use* Aetiology of disease states* Presentation of conditions* Investigations and diagnostic testing* Drug therapy including adverse drug reactions* Drug interactions* Contra-indicationsThe questions are presented as four practice tests, each consisting of 80 MCQs presented in a variety of formats.MCQs in Clinical Pharmacy is an indispensable aid for anyone preparing to sit a multiple choice question examination in pharmacy and for those carrying out a self-evaluation exercise for continuing professional development.A further 20 MCQs are available online at www.pharmpress.com/onlineresourcesLilian M Azzopardi is Senior Lecturer at the Department of Pharmacy, University of Malta, Malta. Related titles from Pharmaceutical Press: MCQs in Pharmacy PracticeFurther MCQs in Pharmacy Practice
Book Synopsis Linne & Ringsrud's Clinical Laboratory Science - E-Book by : Mary Louise Turgeon
Download or read book Linne & Ringsrud's Clinical Laboratory Science - E-Book written by Mary Louise Turgeon and published by Elsevier Health Sciences. This book was released on 2014-04-14 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and easy-to-use, Linne & Ringsrud's Clinical Laboratory Science: The Basics and Routine Techniques, 6th Edition delivers a fundamental overview of the laboratory skills and techniques essential for success in your classes and your career. Author Mary Louise Turgeon's simple, straightforward writing clarifies complex concepts, and a discipline-by-discipline approach helps you build the knowledge to confidently perform clinical laboratory tests and ensure accurate, effective results. Expert insight from respected educator and author Mary Louise Turgeon reflects the full spectrum of clinical laboratory science. Engaging full-color design and illustrations familiarize you with what you'll see under the microscope. Streamlined approach makes must-know concepts and practices more accessible. Broad scope provides an ideal introduction to clinical laboratory science at various levels, including MLS/MLT and Medical Assisting. Hands-on procedures guide you through the exact steps you'll perform in the lab. Learning objectives help you identify key chapter content and study more effectively. Case studies challenge you to apply concepts to realistic scenarios. Review questions at the end of each chapter help you assess your understanding and identify areas requiring additional study. A companion Evolve website provides convenient online access to procedures, glossary, audio glossary and links to additional information. Updated instrumentation coverage familiarizes you with the latest technological advancements in clinical laboratory science. Perforated pages make it easy for you to take procedure instructions with you into the lab. Enhanced organization helps you study more efficiently and quickly locate the information you need. Convenient glossary provides fast, easy access to definitions of key terms.
Download or read book Medicine for MRCP written by Rupa Bessant and published by Oxford University Press. This book was released on 2020-08-17 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine for MRCP provides a comprehensive review of the material that you need to pass the MRCP Parts 1 and 2 written papers. The twenty-seven chapters mapped out to the RCP syllabus, cover all areas from molecular medicine and genetics, through to medical law and ethics. Written by specialist contributors and educational experts, the content is carefully crafted to build your understanding for both papers. Each chapter begins with the basic science required for Part 1, before covering clinical medicine for Part 1, Part 2 and the PACES examinations. To ensure effective revision, material is presented in short sections with bullet lists, tables, and boxes. Over 150 drawings and photos illustrate key principles and clinical topics making them easier to retain. References to evidence-based protocols and directions to further reading allow for deeper understanding. Candidates can review their progress via the 180 end-of chapter self-assessment questions. Drawing on the authors' expertise, Medicine for MRCP is the ideal companion for the MRCP as well as a useful reference guide for practicing medical doctors.
Book Synopsis Anesthetic Pharmacology by : Alex S. Evers
Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
