Global Sensitivity Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 9780470725177
Total Pages : 304 pages
Book Rating : 4.7/5 (251 download)

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Book Synopsis Global Sensitivity Analysis by : Andrea Saltelli

Download or read book Global Sensitivity Analysis written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex mathematical and computational models are used in all areas of society and technology and yet model based science is increasingly contested or refuted, especially when models are applied to controversial themes in domains such as health, the environment or the economy. More stringent standards of proofs are demanded from model-based numbers, especially when these numbers represent potential financial losses, threats to human health or the state of the environment. Quantitative sensitivity analysis is generally agreed to be one such standard. Mathematical models are good at mapping assumptions into inferences. A modeller makes assumptions about laws pertaining to the system, about its status and a plethora of other, often arcane, system variables and internal model settings. To what extent can we rely on the model-based inference when most of these assumptions are fraught with uncertainties? Global Sensitivity Analysis offers an accessible treatment of such problems via quantitative sensitivity analysis, beginning with the first principles and guiding the reader through the full range of recommended practices with a rich set of solved exercises. The text explains the motivation for sensitivity analysis, reviews the required statistical concepts, and provides a guide to potential applications. The book: Provides a self-contained treatment of the subject, allowing readers to learn and practice global sensitivity analysis without further materials. Presents ways to frame the analysis, interpret its results, and avoid potential pitfalls. Features numerous exercises and solved problems to help illustrate the applications. Is authored by leading sensitivity analysis practitioners, combining a range of disciplinary backgrounds. Postgraduate students and practitioners in a wide range of subjects, including statistics, mathematics, engineering, physics, chemistry, environmental sciences, biology, toxicology, actuarial sciences, and econometrics will find much of use here. This book will prove equally valuable to engineers working on risk analysis and to financial analysts concerned with pricing and hedging.

Sensitivity Analysis in Practice

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Publisher : John Wiley & Sons
ISBN 13 : 047087094X
Total Pages : 232 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Sensitivity Analysis in Practice by : Andrea Saltelli

Download or read book Sensitivity Analysis in Practice written by Andrea Saltelli and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitivity analysis should be considered a pre-requisite for statistical model building in any scientific discipline where modelling takes place. For a non-expert, choosing the method of analysis for their model is complex, and depends on a number of factors. This book guides the non-expert through their problem in order to enable them to choose and apply the most appropriate method. It offers a review of the state-of-the-art in sensitivity analysis, and is suitable for a wide range of practitioners. It is focussed on the use of SIMLAB – a widely distributed freely-available sensitivity analysis software package developed by the authors – for solving problems in sensitivity analysis of statistical models. Other key features: Provides an accessible overview of the current most widely used methods for sensitivity analysis. Opens with a detailed worked example to explain the motivation behind the book. Includes a range of examples to help illustrate the concepts discussed. Focuses on implementation of the methods in the software SIMLAB - a freely-available sensitivity analysis software package developed by the authors. Contains a large number of references to sources for further reading. Authored by the leading authorities on sensitivity analysis.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

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Publisher : Government Printing Office
ISBN 13 : 1587634236
Total Pages : 236 pages
Book Rating : 4.5/5 (876 download)

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Book Synopsis Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide by : Agency for Health Care Research and Quality (U.S.)

Download or read book Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Sensitivity Analysis

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Publisher : Springer
ISBN 13 : 3319522590
Total Pages : 291 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Sensitivity Analysis by : Emanuele Borgonovo

Download or read book Sensitivity Analysis written by Emanuele Borgonovo and published by Springer. This book was released on 2017-04-19 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an expository introduction to the methodology of sensitivity analysis of model output. It is primarily intended for investigators, students and researchers that are familiar with mathematical models but are less familiar with the techniques for performing their sensitivity analysis. A variety of sensitivity methods have been developed over the years. This monograph helps the analyst in her/his first exploration of this world. The main goal is to foster the recognition of the crucial role of sensitivity analysis methods as the techniques that allow us to gain insights from quantitative models. Also, exercising rigor in performing sensitivity analysis becomes increasingly relevant both to decision makers and modelers. The book helps the analyst in structuring her/his sensitivity analysis quest properly, so as to obtain the correct answer to the corresponding managerial question. The first part of the book covers Deterministic Methods, including Tornado Diagrams; One-Way Sensitivity Analysis; Differentiation-Based Methods and Local Sensitivity Analysis with Constraints. The second part looks at Probabilistic Methods, including Regression-Based methods, Variance-Based Methods, and Distribution-Based methods. The final section looks at Applications, including capital budgeting, sensitivity analysis in climate change modelling and in the risk assessment of a lunar space mission.

Statistical Methods for Environmental Pollution Monitoring

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Publisher : John Wiley & Sons
ISBN 13 : 9780471288787
Total Pages : 354 pages
Book Rating : 4.2/5 (887 download)

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Book Synopsis Statistical Methods for Environmental Pollution Monitoring by : Richard O. Gilbert

Download or read book Statistical Methods for Environmental Pollution Monitoring written by Richard O. Gilbert and published by John Wiley & Sons. This book was released on 1987-02-15 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses a broad range of statistical design and analysis methods that are particularly well suited to pollution data. It explains key statistical techniques in easy-to-comprehend terms and uses practical examples, exercises, and case studies to illustrate procedures. Dr. Gilbert begins by discussing a space-time framework for sampling pollutants. He then shows how to use statistical sample survey methods to estimate average and total amounts of pollutants in the environment, and how to determine the number of field samples and measurements to collect for this purpose. Then a broad range of statistical analysis methods are described and illustrated. These include: * determining the number of samples needed to find hot spots * analyzing pollution data that are lognormally distributed * testing for trends over time or space * estimating the magnitude of trends * comparing pollution data from two or more populations New areas discussed in this sourcebook include statistical techniques for data that are correlated, reported as less than the measurement detection limit, or obtained from field-composited samples. Nonparametric statistical analysis methods are emphasized since parametric procedures are often not appropriate for pollution data. This book also provides an illustrated comprehensive computer code for nonparametric trend detection and estimation analyses as well as nineteen statistical tables to permit easy application of the discussed statistical techniques. In addition, many publications are cited that deal with the design of pollution studies and the statistical analysis of pollution data. This sourcebook will be a useful tool for applied statisticians, ecologists, radioecologists, hydrologists, biologists, environmental engineers, and other professionals who deal with the collection, analysis, and interpretation of pollution in air, water, and soil.

Risk Assessment Methods for Biological and Chemical Hazards in Food

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Publisher : CRC Press
ISBN 13 : 1498762034
Total Pages : 547 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Risk Assessment Methods for Biological and Chemical Hazards in Food by : Fernando Pérez-Rodríguez

Download or read book Risk Assessment Methods for Biological and Chemical Hazards in Food written by Fernando Pérez-Rodríguez and published by CRC Press. This book was released on 2020-10-28 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has been extensively developed in several scientific fields, such as environmental science, economics, and civil engineering, among others. In the aftermath of the SPS and GATT agreements on the use of risk analysis framework in food trade, signed in the 1990s, international organisations and governments adopted risk assessment as a science-based process to ensure food safety along the food chain. The food industry can also benefit from the use of this approach for food process optimisation and quality assurance. Risk Assessment Methods for Biological and Chemical Hazards in Food introduces the reader to quantitative risk assessment methods encompassing general concepts to specific applications to biological and chemical hazards in foods. In the first section, the book presents food risk assessment as methodology and addresses, more specifically, new trends and approaches such as the development of risk rating methods, risk metrics, risk-benefit assessment studies and quality assessment methods. Section II is dedicated to biological hazards. This section identifies the most relevant biological hazards along the food chain and provides an overview on the types of predictive microbiology models used to describe the microbial response along the food chain. Chapter 12 specifically deals with cross contamination and the quantitative methods that can be applied to describe this relevant microbial process. The development and application of dose-response models (i.e. mathematical function describing the relationship between pathogen dose and health response) are also covered in this section. In Section III, the book translates risk assessment concepts into the area of chemical hazards, defining the process steps to determine chemical risk and describing the uncertainty and variability sources associated with chemicals. Key Features: Presents new trends and approaches in the field of risk assessment in foods Risk assessment concepts are illustrated by practical examples in the food sector Discusses how quantitative information and models are integrated in a quantitative risk asssment framework Provides examples of applications of quantitative chemical risk assessment in risk management The book, written by renowned experts in their field, is a comprehensive collection of quantitative methods and approaches applied to risk assessment in foods. It can be used as an extensive guide for food safety practitioners and researchers to perform quantitative risk assessment in foods

Safety, Reliability and Risk Analysis

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Publisher : CRC Press
ISBN 13 : 1315815591
Total Pages : 3422 pages
Book Rating : 4.3/5 (158 download)

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Book Synopsis Safety, Reliability and Risk Analysis by : R.D.J.M. Steenbergen

Download or read book Safety, Reliability and Risk Analysis written by R.D.J.M. Steenbergen and published by CRC Press. This book was released on 2013-09-18 with total page 3422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of risk and reliability analysis are becoming increasingly important as decision support tools in various fields of engineering. Safety, Reliability and Risk Analysis: Beyond the Horizon covers a wide range of topics for which risk analysis forms an indispensable field of knowledge to ensure sufficient safety.

Probabilistic Risk Analysis

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Publisher : Cambridge University Press
ISBN 13 : 9780521773201
Total Pages : 228 pages
Book Rating : 4.7/5 (732 download)

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Book Synopsis Probabilistic Risk Analysis by : Tim Bedford

Download or read book Probabilistic Risk Analysis written by Tim Bedford and published by Cambridge University Press. This book was released on 2001-04-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic risk analysis aims to quantify the risk caused by high technology installations. Increasingly, such analyses are being applied to a wider class of systems in which problems such as lack of data, complexity of the systems, uncertainty about consequences, make a classical statistical analysis difficult or impossible. The authors discuss the fundamental notion of uncertainty, its relationship with probability, and the limits to the quantification of uncertainty. Drawing on extensive experience in the theory and applications of risk analysis, the authors focus on the conceptual and mathematical foundations underlying the quantification, interpretation and management of risk. They cover standard topics as well as important new subjects such as the use of expert judgement and uncertainty propagation. The relationship of risk analysis with decision making is highlighted in chapters on influence diagrams and decision theory. Finally, the difficulties of choosing metrics to quantify risk, and current regulatory frameworks are discussed.

Goodness-of-Fit-Techniques

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Publisher : Routledge
ISBN 13 : 1351444565
Total Pages : 585 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Goodness-of-Fit-Techniques by : RalphB. D'Agostino

Download or read book Goodness-of-Fit-Techniques written by RalphB. D'Agostino and published by Routledge. This book was released on 2017-10-19 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conveniently grouping methods by techniques, such as chi-squared and empirical distributionfunction , and also collecting methods of testing for specific famous distributions, this usefulreference is the fust comprehensive.review of the extensive literature on the subject. It surveysthe leading methods of testing fit . .. provides tables to make the tests available . .. assessesthe comparative merits of different test procedures . .. and supplies numerical examples to aidin understanding these techniques.Goodness-of-Fit Techniques shows how to apply the techniques . .. emphasizes testing for thethree major distributions, normal, exponential, and uniform . .. discusses the handling of censoreddata .. . and contains over 650 bibliographic citations that cover the field.Illustrated with tables and drawings, this volume is an ideal reference for mathematical andapplied statisticians, and biostatisticians; professionals in applied science fields, including psychologists,biometricians , physicians, and quality control and reliability engineers; advancedundergraduate- and graduate-level courses on goodness-of-fit techniques; and professional seminarsand symposia on applied statistics, quality control, and reliability.

The Uncertainty Analysis of Model Results

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Publisher : Springer
ISBN 13 : 3319762974
Total Pages : 355 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Uncertainty Analysis of Model Results by : Eduard Hofer

Download or read book The Uncertainty Analysis of Model Results written by Eduard Hofer and published by Springer. This book was released on 2018-05-02 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide to the uncertainty analysis of computer model applications. Used in many areas, such as engineering, ecology and economics, computer models are subject to various uncertainties at the level of model formulations, parameter values and input data. Naturally, it would be advantageous to know the combined effect of these uncertainties on the model results as well as whether the state of knowledge should be improved in order to reduce the uncertainty of the results most effectively. The book supports decision-makers, model developers and users in their argumentation for an uncertainty analysis and assists them in the interpretation of the analysis results.

Science and Judgment in Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 030904894X
Total Pages : 668 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Science and Judgment in Risk Assessment by : National Research Council

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

The Owner's Role in Project Risk Management

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Publisher : National Academies Press
ISBN 13 : 0309181615
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Owner's Role in Project Risk Management by : National Research Council

Download or read book The Owner's Role in Project Risk Management written by National Research Council and published by National Academies Press. This book was released on 2005-02-25 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective risk management is essential for the success of large projects built and operated by the Department of Energy (DOE), particularly for the one-of-a-kind projects that characterize much of its mission. To enhance DOE's risk management efforts, the department asked the NRC to prepare a summary of the most effective practices used by leading owner organizations. The study's primary objective was to provide DOE project managers with a basic understanding of both the project owner's risk management role and effective oversight of those risk management activities delegated to contractors.

Hayes' Principles and Methods of Toxicology, Sixth Edition

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Publisher : CRC Press
ISBN 13 : 1842145363
Total Pages : 2186 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Hayes' Principles and Methods of Toxicology, Sixth Edition by : A. Wallace Hayes

Download or read book Hayes' Principles and Methods of Toxicology, Sixth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2014-10-10 with total page 2186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.

Basics and Trends in Sensitivity Analysis: Theory and Practice in R

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Publisher : SIAM
ISBN 13 : 1611976693
Total Pages : 307 pages
Book Rating : 4.6/5 (119 download)

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Book Synopsis Basics and Trends in Sensitivity Analysis: Theory and Practice in R by : Sébastien Da Veiga

Download or read book Basics and Trends in Sensitivity Analysis: Theory and Practice in R written by Sébastien Da Veiga and published by SIAM. This book was released on 2021-10-14 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of global sensitivity analysis methods and algorithms, including their theoretical basis and mathematical properties. The authors use a practical point of view and real case studies as well as numerous examples, and applications of the different approaches are illustrated throughout using R code to explain their usage and usefulness in practice. Basics and Trends in Sensitivity Analysis: Theory and Practice in R covers a lot of material, including theoretical aspects of Sobol’ indices as well as sampling-based formulas, spectral methods, and metamodel-based approaches for estimation purposes; screening techniques devoted to identifying influential and noninfluential inputs; variance-based measures when model inputs are statistically dependent (and several other approaches that go beyond variance-based sensitivity measures); and a case study in R related to a COVID-19 epidemic model where the full workflow of sensitivity analysis combining several techniques is presented. This book is intended for engineers, researchers, and undergraduate students who use complex numerical models and have an interest in sensitivity analysis techniques and is appropriate for anyone with a solid mathematical background in basic statistical and probability theories who develops and uses numerical models in all scientific and engineering domains.

Probabilistic Techniques in Exposure Assessment

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306459573
Total Pages : 294 pages
Book Rating : 4.4/5 (595 download)

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Book Synopsis Probabilistic Techniques in Exposure Assessment by : Alison C. Cullen

Download or read book Probabilistic Techniques in Exposure Assessment written by Alison C. Cullen and published by Springer Science & Business Media. This book was released on 1999-07-31 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this text, experts provide a complete sourcebook on methods for addressing variability and uncertainty in exposure analysis.

Sensitivity Analysis in Earth Observation Modelling

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Publisher : Elsevier
ISBN 13 : 0128030313
Total Pages : 448 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Sensitivity Analysis in Earth Observation Modelling by : George P. Petropoulos

Download or read book Sensitivity Analysis in Earth Observation Modelling written by George P. Petropoulos and published by Elsevier. This book was released on 2016-10-07 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensitivity Analysis in Earth Observation Modeling highlights the state-of-the-art in ongoing research investigations and new applications of sensitivity analysis in earth observation modeling. In this framework, original works concerned with the development or exploitation of diverse methods applied to different types of earth observation data or earth observation-based modeling approaches are included. An overview of sensitivity analysis methods and principles is provided first, followed by examples of applications and case studies of different sensitivity/uncertainty analysis implementation methods, covering the full spectrum of sensitivity analysis techniques, including operational products. Finally, the book outlines challenges and future prospects for implementation in earth observation modeling. Information provided in this book is of practical value to readers looking to understand the principles of sensitivity analysis in earth observation modeling, the level of scientific maturity in the field, and where the main limitations or challenges are in terms of improving our ability to implement such approaches in a wide range of applications. Readers will also be informed on the implementation of sensitivity/uncertainty analysis on operational products available at present, on global and continental scales. All of this information is vital in the selection process of the most appropriate sensitivity analysis method to implement. - Outlines challenges and future prospects of sensitivity analysis implementation in earth observation modeling - Provides readers with a roadmap for directing future efforts - Includes case studies with applications from different regions around the globe, helping readers to explore strengths and weaknesses of the different methods in earth observation modeling - Presents a step-by-step guide, providing the principles of each method followed by the application of variants, making the reference easy to use and follow

Uncertainty

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Publisher : Cambridge University Press
ISBN 13 : 9780521427449
Total Pages : 354 pages
Book Rating : 4.4/5 (274 download)

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Book Synopsis Uncertainty by : Millett Granger Morgan

Download or read book Uncertainty written by Millett Granger Morgan and published by Cambridge University Press. This book was released on 1990 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A risk analysis textbook which is intended as a basic text for students as well as a reference for practitioners and researchers. It provides a basis for policy analysis and draws upon a variety of case studies.