Hayes Principles And Methods Of Toxicology Sixth Edition

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Hayes' Principles and Methods of Toxicology, Sixth Edition

Author : A. Wallace Hayes
Publisher : CRC Press
ISBN 13 : 1842145363
Total Pages : 2186 pages
Book Rating : 4.8/5 (421 download)

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Book Synopsis Hayes' Principles and Methods of Toxicology, Sixth Edition by : A. Wallace Hayes

Download or read book Hayes' Principles and Methods of Toxicology, Sixth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2014-10-10 with total page 2186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.

Hayes' Principles and Methods of Toxicology

Author : A. Wallace Hayes
Publisher : CRC Press
ISBN 13 : 1000875776
Total Pages : 2143 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Hayes' Principles and Methods of Toxicology by : A. Wallace Hayes

Download or read book Hayes' Principles and Methods of Toxicology written by A. Wallace Hayes and published by CRC Press. This book was released on 2023-07-03 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.

Hayes' Principles and Methods of Toxicology

Author : A Wallace Hayes
Publisher :
ISBN 13 : 9780367611545
Total Pages : 0 pages
Book Rating : 4.6/5 (115 download)

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Book Synopsis Hayes' Principles and Methods of Toxicology by : A Wallace Hayes

Download or read book Hayes' Principles and Methods of Toxicology written by A Wallace Hayes and published by . This book was released on 2023-04-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes' Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. Principles of Toxicology), major classes of established chemical hazards (Section II. Agents), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. Methods), as well as toxicology of specific target systems and organs (Section IV. Organ- and System-Specific Toxicology). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.

Principles and Methods of Toxicology, Fifth Edition

Author : A. Wallace Hayes
Publisher : CRC Press
ISBN 13 : 9780849337789
Total Pages : 2304 pages
Book Rating : 4.3/5 (377 download)

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Book Synopsis Principles and Methods of Toxicology, Fifth Edition by : A. Wallace Hayes

Download or read book Principles and Methods of Toxicology, Fifth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2007-09-25 with total page 2304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Loomis's Essentials of Toxicology

Author : Ted A. Loomis
Publisher : Elsevier
ISBN 13 : 0080535631
Total Pages : 282 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Loomis's Essentials of Toxicology by : Ted A. Loomis

Download or read book Loomis's Essentials of Toxicology written by Ted A. Loomis and published by Elsevier. This book was released on 1996-03-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under discussion. This text is an invaluable resource for toxicologists as well as a comprehensive introduction to the topic for graduate and advanced undergraduate students in toxicology and public health. The "classic textbook" in toxicology Completely revised and updated Includes both principles and methods Requires minimal background in chemistry and biology

Principles and Methods of Toxicology (student Edition)

Author : A. W. Hayes
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (636 download)

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Book Synopsis Principles and Methods of Toxicology (student Edition) by : A. W. Hayes

Download or read book Principles and Methods of Toxicology (student Edition) written by A. W. Hayes and published by . This book was released on 1986 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles and Methods of Toxicology

Author : A. Wallace Hayes
Publisher :
ISBN 13 : 9780881674392
Total Pages : 445 pages
Book Rating : 4.6/5 (743 download)

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Book Synopsis Principles and Methods of Toxicology by : A. Wallace Hayes

Download or read book Principles and Methods of Toxicology written by A. Wallace Hayes and published by . This book was released on 1995 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Loomis's Essentials of Toxicology

Author : A. Wallace Hayes
Publisher : Academic Press
ISBN 13 : 9780128159217
Total Pages : 0 pages
Book Rating : 4.1/5 (592 download)

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Book Synopsis Loomis's Essentials of Toxicology by : A. Wallace Hayes

Download or read book Loomis's Essentials of Toxicology written by A. Wallace Hayes and published by Academic Press. This book was released on 2019-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health.

Principles and Methods of Toxicology

Author : A. Wallace Hayes
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780881670028
Total Pages : 750 pages
Book Rating : 4.6/5 (7 download)

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Book Synopsis Principles and Methods of Toxicology by : A. Wallace Hayes

Download or read book Principles and Methods of Toxicology written by A. Wallace Hayes and published by Lippincott Williams & Wilkins. This book was released on 1984-01 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hefty and authoritative, the new edition of this reference and text (suitable for graduate level teaching) contains 37 contributed chapters arranged in sections on principles, agents, and methods of toxicology. They provide a state-of-the-art exposition of information related to the task of identifying whether or not a causal relationship exists between specific doses of a chemical and an alleged adverse effect. Current testing procedures, guidelines on data interpretation, and areas of current controversy are covered; new chapters in this edition expand coverage of epidemiology, exposure assessment, and repeat dosing. Editor Hayes is an executive in charge of product integrity at The Gillette Company; contributors are from companies and institutions all over the US. c. Book News Inc.

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Author : Steve Gilbert
Publisher : Academic Press
ISBN 13 : 0128137258
Total Pages : 1055 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Information Resources in Toxicology, Volume 1: Background, Resources, and Tools by : Steve Gilbert

Download or read book Information Resources in Toxicology, Volume 1: Background, Resources, and Tools written by Steve Gilbert and published by Academic Press. This book was released on 2020-05-16 with total page 1055 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals Explores recent internet trends, web-based databases, and software tools in a section on the online environment Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

Hayes' Handbook of Pesticide Toxicology

Author :
Publisher : Academic Press
ISBN 13 : 0080922015
Total Pages : 2407 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Hayes' Handbook of Pesticide Toxicology by :

Download or read book Hayes' Handbook of Pesticide Toxicology written by and published by Academic Press. This book was released on 2010-02-15 with total page 2407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

History of Food and Nutrition Toxicology

Author : Esther Haugabrooks
Publisher : Academic Press
ISBN 13 : 0128212624
Total Pages : 350 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis History of Food and Nutrition Toxicology by : Esther Haugabrooks

Download or read book History of Food and Nutrition Toxicology written by Esther Haugabrooks and published by Academic Press. This book was released on 2023-08-25 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: History of Food and Nutrition Toxicology, part of the History of Toxicology and Environmental Health series, provides an overview of history in the field to help readers better understand future applications for evaluating newer and valuable approaches and their impacts on human health. The book explores issues associated with chemical contaminants, toxicants, the use of dietary supplements and pharmaceuticals, and increasing concerns surrounding food toxicity and safety. The addition of historical case studies and end-of chapter questions make the book ideal for toxicologists, food scientists, pharmaceutical scientists, and other researchers who want to understand current state and future challenges in the field. Offers thought-provoking, forward thinking end-of-chapter questions Provides illustrations of historical products, individuals and processes Discusses case studies that help provide historical perspectives

Toxicological Risk Assessment for Beginners

Author : José A. Torres
Publisher : Springer
ISBN 13 : 3319127519
Total Pages : 250 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Toxicological Risk Assessment for Beginners by : José A. Torres

Download or read book Toxicological Risk Assessment for Beginners written by José A. Torres and published by Springer. This book was released on 2015-03-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypothetical case studies. Toxicological Risk Assessment for Beginners aims not to create an expert, but rather to provide readers with their first understanding of the risk assessment topic. This book was designed with the student in mind. We simplify a complex process for beginners and balance theory with practical aspects, but remain fluid enough to increase difficulty with case studies. By incorporating an action based, step by step approach to learning the risk assessment process, this book provides its readers with an elementary understanding of how the risk assessment process is initiated, developed and finished, making it a valuable guide for graduate students, post-doctoral fellows and early career scientists in industry.

Aerobiology

Author : Harry Salem
Publisher : Royal Society of Chemistry
ISBN 13 : 1849737916
Total Pages : 518 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Aerobiology by : Harry Salem

Download or read book Aerobiology written by Harry Salem and published by Royal Society of Chemistry. This book was released on 2016-04-19 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aerobiology is the study of airborne organic particulates in the environment, such as bacteria or fungal spores. These can be either naturally occurring or artificially introduced into the air. Some of the toxicological, pharmacological, and physiological effects of bioaerosols include infections, allergies, and cancer. Research efforts in aerobiology range from remediating household mould to combating bioterrorism. This book focusses on the toxicological aspects of aerobiology, considering the adverse health effects associated with the inhalation of specific bioaerosols, such as anthrax and ricin. Additionally, chapters cover techniques for generating, sampling and characterizing airborne biological materials as well as methods for establishing standards of exposure. Moreover, mitigation of exposure and protection against exposure are described. Bringing together the contemporary status of information in the area, this book will be a valuable reference book for pulmonary specialists, general practitioners of medicine, public health and public safety officers, first responders, military personnel, and students studying toxicology and related disciplines.

Chemical Warfare Agents

Author : Brian J. Lukey
Publisher : CRC Press
ISBN 13 : 0429632967
Total Pages : 826 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Chemical Warfare Agents by : Brian J. Lukey

Download or read book Chemical Warfare Agents written by Brian J. Lukey and published by CRC Press. This book was released on 2019-04-11 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11, 2001. The second edition titled, Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, included new epidemiological and clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment. Since the second edition, the chemical warfare agent community has worked hard to advance research for protection and treatment and develop/improve response approaches for individuals and definitive care. Consequently, in addition to updating previous chapters, Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response, Third Edition features several new chapters that address the Syrian War, chemical destruction, the Organisation for the Prohibition of Chemical Weapons, biomarkers for chemical warfare agent exposure, field sensors, aircraft decontamination, lung/human on a chip, chemical warfare response decision making, and other research advancements. Features: Describes the newest medical interventions, and the latest technologies deployed in the field, as well as developments in the international response to CW usage highlighting recent events in the Middle East Discusses the latest in organizational/interagency partitioning in terms of responsibilities for emergency response, not just in the United States but at the international level—whether prevention, mitigation, medical care, reclamation, or medico-legal aspects of such response Contains the most current research from bench-level experts The third edition contains the most up-to-date and comprehensive coverage of the question of chemical warfare agent employment on the battlefield or in terrorism. Edited by workers that have been in the field for 35+ years, it remains faithful to the scientific "constants," while evaluating and crediting the advances by the industry that have made us safer.

Hazardous Wastes

Author : Richard J. Watts
Publisher : John Wiley & Sons
ISBN 13 : 1119634059
Total Pages : 724 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Hazardous Wastes by : Richard J. Watts

Download or read book Hazardous Wastes written by Richard J. Watts and published by John Wiley & Sons. This book was released on 2023-05-09 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hazardous Wastes An illuminating, problem-solving approach to source area analysis, environmental chemodynamics, risk assessment, and remediation In the newly revised second edition of Hazardous Wastes: Assessment and Remediation, a team of distinguished researchers delivers a foundational and comprehensive treatment of all aspects of hazardous waste problems. The book offers two sections—one on assessment and the following on remediation—while exploring topics crucial to the study of environmental science and engineering at the senior or master’s level. This latest edition includes a new emphasis on the chemistry of emerging contaminants, including perfluorinated compounds, 1,4-dioxane, methyl tert-butyl ether, and personal care products. It also offers updated data on contaminant Threshold Limit Value, Reference Dose, Slope Factor, Reference Concentration, and Inhalation Unit Risk. New remediation chapters also provide many design problems, incorporating economic analyses and the selection of various design alternatives. Approximately 200 new end-of-chapter problems—with solutions—have been added as well. Readers will also find: A thorough introduction to hazardous wastes, including discussion of pre-regulatory disposal and hazardous waste legislation Comprehensive discussions of common hazardous wastes, including their nomenclature, industrial uses, and disposal histories In-depth explorations of partitioning, sorption, and exchange at surfaces, as well as volatilization Extensive descriptions of the concepts of hazardous waste toxicology and quantitative toxicology Perfect for senior- and masters-level college courses in hazardous wastes in Environmental Science, Environmental Engineering, Civil Engineering, or Chemical Engineering programs, Hazardous Wastes: Assessment and Remediation will also earn a place in the libraries of professional environmental scientists and engineers.

Loomis's Essentials of Toxicology

Author : A. Wallace Hayes
Publisher : Academic Press
ISBN 13 : 0128159227
Total Pages : 272 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Loomis's Essentials of Toxicology by : A. Wallace Hayes

Download or read book Loomis's Essentials of Toxicology written by A. Wallace Hayes and published by Academic Press. This book was released on 2019-10-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health. Provides a revised and updated edition of one of the "gold" works in the field Includes both principles and methods Requires minimal background in chemistry and biology Expanded Information Sources in Toxicology