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Author : Francesco De Matteis
Publisher : Springer
ISBN 13 : 1349087599
Total Pages : 305 pages
Book Rating : 4.3/5 (49 download)
Download or read book Selectivity and Molecular Mechanisms of Toxicity written by Francesco De Matteis and published by Springer. This book was released on 1987-06-18 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Adrien Albert
Publisher : Chapman & Hall
ISBN 13 : 9780412260100
Total Pages : 750 pages
Book Rating : 4.2/5 (61 download)
Download or read book Selective Toxicity written by Adrien Albert and published by Chapman & Hall. This book was released on 1985 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Urs A. Boelsterli
Publisher : CRC Press
ISBN 13 : 9780849372728
Total Pages : 424 pages
Book Rating : 4.3/5 (727 download)
Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Author : H. Rašková
Publisher : Elsevier
ISBN 13 : 1483157202
Total Pages : 113 pages
Book Rating : 4.4/5 (831 download)
Download or read book Mechanisms of Drug Toxicity written by H. Rašková and published by Elsevier. This book was released on 2013-10-22 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)
Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Author :
Publisher :
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Toxicological Profile for Acrolein written by and published by . This book was released on 2007 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alan H. Hall
Publisher : John Wiley & Sons
ISBN 13 : 1118628942
Total Pages : 369 pages
Book Rating : 4.1/5 (186 download)
Download or read book Toxicology of Cyanides and Cyanogens written by Alan H. Hall and published by John Wiley & Sons. This book was released on 2015-10-13 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic and applied toxicology of cyanides and cyanogens has widespread commercial, occupational, environmental, clinical, forensic, military, and public health implications. This book provides a detailed and updated reference describing the properties, uses, general and human toxicology, clinical recognition, diagnosis and medical management, and countermeasures is therefore required in academic, medical, occupational, environmental, medico-legal, regulatory, emergency response, and military arenas. Edited by a world-renowned team of experts from academia, defense and industry, this book will be an invaluable reference for professionals, researchers and students in cyanide and cyanogens.
Author : Simon J. Yu
Publisher : CRC Press
ISBN 13 : 1420059769
Total Pages : 294 pages
Book Rating : 4.4/5 (2 download)
Download or read book The Toxicology and Biochemistry of Insecticides written by Simon J. Yu and published by CRC Press. This book was released on 2011-03-05 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research
Author : Bill Carlile
Publisher : Cambridge University Press
ISBN 13 : 113945756X
Total Pages : 282 pages
Book Rating : 4.1/5 (394 download)
Download or read book Pesticide Selectivity, Health and the Environment written by Bill Carlile and published by Cambridge University Press. This book was released on 2006-09-28 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effects of artificial (and natural) pesticides on organisms other than the target organisms and on the environment in general have become increasingly important in recent years. This has been accentuated by the concerns over the damage these products can do to human health. This book considers pesticides from their fundamental properties as selective control agents. In the first part of this book, the mechanisms of action and basis of selectivity are considered for herbicides including plant growth regulators, fungicides, insecticides, vertebrate control agents and the dose rates required to achieve the desired effects. The second part of the book uses these factors to address environmental and health concerns about pesticides. Key features include descriptions of modern pesticides, modern risk assessments for both environment and public health, and a final comparative chapter on relative risk analysis of pesticides.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309045312
Total Pages : 167 pages
Book Rating : 4.3/5 (9 download)
Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Author : R. Navanietha Krishnaraj
Publisher : John Wiley & Sons
ISBN 13 : 1119617197
Total Pages : 420 pages
Book Rating : 4.1/5 (196 download)
Download or read book Microbial Interactions at Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-11-02 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.
Author : Dharmendra K. Gupta
Publisher : Springer Science & Business Media
ISBN 13 : 3642384692
Total Pages : 245 pages
Book Rating : 4.6/5 (423 download)
Download or read book Heavy Metal Stress in Plants written by Dharmendra K. Gupta and published by Springer Science & Business Media. This book was released on 2013-08-04 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants possess a range of potential cellular mechanisms that may be involved in the detoxification of heavy metals and thus tolerance to metal stress. Metal toxicity causes multiple direct and indirect effects in plants that concern practically all physiological functions. The main purpose of this book is to present comprehensive and concise information on recent advances in the field of metal transport and how genetic diversity affects heavy metal transport in plants. Other key futures of the book are related to metal toxicity and detoxification mechanisms, biochemical tools for HM remediation processes, molecular mechanisms for HM detoxification, how metallomics and metalloproteomics are affected by heavy metal stress in plants, and the role of ROS metabolism in the alleviation of heavy metals. Some chapters also focus on recent developments in the field of phytoremediation. Overall the book presents in-depth information and the most essential advances in the field of heavy metal toxicity in plants in recent years.
Author : Hugh MacPherson
Publisher : Elsevier Health Sciences
ISBN 13 : 0443100292
Total Pages : 288 pages
Book Rating : 4.4/5 (431 download)
Download or read book Acupuncture Research written by Hugh MacPherson and published by Elsevier Health Sciences. This book was released on 2007-10-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to set out a full range of research strategies for evaluating the clinical practice of acupuncture. Leading acupuncturists and researchers with international reputations share their expertise. They illustrate their descriptions with practical examples of what has worked and what has not. It outlines many of the key challenges in the field. These challenges relate to the nature of acupuncture and the gap between current research evidence and the actual experiences of acupuncturists in the field. By focusing the chapters on key research questions, rather than methods, the book has a user-friendly feel. Each chapter is easily accessible with brief explanations of research designs as well as vignettes of relevant past research. The book is based on a deep understanding of acupuncture, with its inherent complexity in practice, whether based on traditional principles or more modern concepts. By incorporating a more sophisticated understanding of the field, this book details a range of strategies aiming to develop the evidence base with the utmost rigour. It is the first book on acupuncture research to take this unique view, integrating the very best of evidence-based medicine with a genuine sensitivity to the discipline of acupuncture, from its traditional and holistic roots to its more modern interpretations.
Author : W. Norman Aldridge
Publisher : CRC Press
ISBN 13 : 9780748404131
Total Pages : 270 pages
Book Rating : 4.4/5 (41 download)
Download or read book Mechanisms and Concepts in Toxicology written by W. Norman Aldridge and published by CRC Press. This book was released on 1996-02-15 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.
Author :
Publisher :
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.3/5 ( download)
Download or read book Molecular Mechanisms of Metal Toxicity and Carcinogenicity written by and published by . This book was released on 1994 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
