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Selective Toxicity
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Book Synopsis Selective Toxicity by : Adrien Albert
Download or read book Selective Toxicity written by Adrien Albert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about selectively toxic agents. That is to say, it is about those substances that affect certain cells without harming others, even when they are close neighbours. Toxicity need not be fatal. It can be made easily reversible, as is the case with general anaesthetics. Selective toxicity covers an immense field: most of the drugs used for treating illness in man and his economic animals, as well as all of the fungicides, insecticides, and weed killers that are used in agriculture. Essentially, this book is a discussion of the physical and chemical means which contribute to selectivity, and this is the basis of molecular pharmacology. _Selective Toxicity began as a course of lectures that Professor F. G. Young encouraged me to give in University College London, in 1948 and again in 1949. The first edition appeared in 1951, as a very small book because little was then known about the factors that provide selectivity. Since those early days, the subject has undergone tremendous development. At first, industry was un receptive to the word 'toxicity', however qualified! Yet the market was being supplied with biologically powerful substances of which several had the potential to cause harm. This aspect was brought to light by two events of the early 1960s. The first of these was the discovery that a sedative, thalidomide, administered to expectant mothers, after what was then considered to be adequate testing, had caused permanent deformities in about 10000 children.
Book Synopsis Selective Toxicity by : Adrien Albert
Download or read book Selective Toxicity written by Adrien Albert and published by Springer. This book was released on 2013-11-22 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Selective Toxicity by : Adrien Albert
Download or read book Selective Toxicity written by Adrien Albert and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Jawetz Melnick & Adelbergs Medical Microbiology 28 E by : Karen C. Carroll
Download or read book Jawetz Melnick & Adelbergs Medical Microbiology 28 E written by Karen C. Carroll and published by McGraw Hill Professional. This book was released on 2019-08-25 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Understand the clinically relevant aspects of microbiology with this student-acclaimed, full-color review --- bolstered by case studies and hundreds of USMLE®-style review questions Since 1954, Jawetz, Melnick & Adelberg’s Medical Microbiology has been hailed by students, instructors, and clinicians as the single-best resource for understanding the roles microorganisms play in human health and illness. Concise and fully up to date, this trusted classic links fundamental principles with the diagnosis and treatment of microbial infections. Along with brief descriptions of each organism, you will find vital perspectives on pathogenesis, diagnostic laboratory tests, clinical findings, treatment, and epidemiology. The book also includes an entire chapter of case studies that focuses on differential diagnosis and management of microbial infections. Here’s why Jawetz, Melnick & Adelberg’s Medical Microbiology is essential for USMLE® review: •640+ USMLE-style review questions •350+ illustrations •140+ tables•22 case studies to sharpen your differential diagnosis and management skills •An easy-to-access list of medically important microorganisms •Coverage that reflects the latest techniques in laboratory and diagnostic technologies •Full-color images and micrographs •Chapter-ending summaries •Chapter concept checks Jawetz, Melnick & Adelberg’s Medical Microbiology, Twenty-Eighth Edition effectively introduces you to basic clinical microbiology through the fields of bacteriology, mycology, and parasitology, giving you a thorough yet understandable review of the discipline. Begin your review with it and see why there is nothing as time tested or effective.
Book Synopsis Selective Toxicity by : Adrien Albert
Download or read book Selective Toxicity written by Adrien Albert and published by Springer. This book was released on 2013-11-27 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Selective Toxicity by : Adrien Albert
Download or read book Selective Toxicity written by Adrien Albert and published by . This book was released on 1951 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Antimicrobial Drugs by : Eric Michael Scholar
Download or read book The Antimicrobial Drugs written by Eric Michael Scholar and published by Oxford University Press, USA. This book was released on 2000 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a thorough updating of a classic text that has been published in three editions since Pratt's Chemotherapy of Infection (OUP, 1973). Its treatment of the mechanisms of action, pharmacology and adverse effects of the drugs used to treat bacterial, fungal, parasitic and viral infectionshas been greatly expanded, and this edition includes two completely new chapters on the fluoroquinolones and the drugs used to treat AIDS. the frugs used to treat AIDS.
Author :Diane S. Aschenbrenner Publisher :Lippincott Williams & Wilkins ISBN 13 :9780781765879 Total Pages :1348 pages Book Rating :4.7/5 (658 download)
Book Synopsis Drug Therapy in Nursing by : Diane S. Aschenbrenner
Download or read book Drug Therapy in Nursing written by Diane S. Aschenbrenner and published by Lippincott Williams & Wilkins. This book was released on 2009 with total page 1348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a totally nursing-focused framework for teaching and learning nursing pharmacology, and "places the patient" at the center of all drug administration decisions and considerations. The book presents core drug knowledge using prototypes of different drug classes and emphasizes core patient variables that influence the patient's response to therapy. This thoroughly updated Third Edition covers newly approved drugs, has separate chapters on drugs affecting fungal and viral infections, and includes more pathophysiology information. FDA Black Box warnings have been added to the discussion of each prototype when applicable, and safety alerts have been added to emphasize prevention of common medication errors. A companion Website offers student and instructor ancillaries including NCLEX®-style questions, pathophysiology animations, medication administration videos, and dosage calculation quizzes.
Download or read book Selective toxicity written by A. Albert and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Disinfection, Sterilization, and Preservation by : Seymour Stanton Block
Download or read book Disinfection, Sterilization, and Preservation written by Seymour Stanton Block and published by Lippincott Williams & Wilkins. This book was released on 2001-01-01 with total page 1448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is a comprehensive, practical reference on contemporary methods of disinfection, sterlization, and preservation and their medical, surgical, and public health applications. New topics covered include recently identified pathogens, microbial biofilms, use of antibiotics as antiseptics, synergism between chemical microbicides, pulsed-light sterilization of pharmaceuticals, and new methods for medical waste management. (Midwest).
Book Synopsis Selective Toxicity and Antibiotics by : Society for Experimental Biology (Great Britain)
Download or read book Selective Toxicity and Antibiotics written by Society for Experimental Biology (Great Britain) and published by . This book was released on 1949 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Book Synopsis Toxic Phosphorus Esters by : Richard D. O'Brien
Download or read book Toxic Phosphorus Esters written by Richard D. O'Brien and published by Elsevier. This book was released on 2016-07-29 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.
Book Synopsis Antimicrobial Chemotherapy by : Roger Finch
Download or read book Antimicrobial Chemotherapy written by Roger Finch and published by OUP Oxford. This book was released on 2012-01-05 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.
Book Synopsis Loomis's Essentials of Toxicology by : A. Wallace Hayes
Download or read book Loomis's Essentials of Toxicology written by A. Wallace Hayes and published by Academic Press. This book was released on 2019-10-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health.
Book Synopsis Mechanistic Toxicology by : Urs A. Boelsterli
Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Book Synopsis Selective Toxicity and Related Topics by : Adrien Albert
Download or read book Selective Toxicity and Related Topics written by Adrien Albert and published by . This book was released on 1968 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
