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Selected Papers Of Frederick Sanger
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Book Synopsis Selected Papers of Frederick Sanger by : Frederick Sanger
Download or read book Selected Papers of Frederick Sanger written by Frederick Sanger and published by World Scientific. This book was released on 1996 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume is mainly concerned with the development of methods for ?sequencing? ? that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
Book Synopsis Chemical Biology, Selected Papers Of H G Khorana (With Introductions) by : H Gobind Khorana
Download or read book Chemical Biology, Selected Papers Of H G Khorana (With Introductions) written by H Gobind Khorana and published by World Scientific. This book was released on 2000-05-24 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first two chapters of this invaluable book trace the developments of the chemistry and macromolecular structures, respectively, of proteins and nuclei acids. Similarly, the introductions to the succeeding chapters review, step by step, the historical landmarks in the topics covered. These include discoveries of biological phosphate esters, nucleotides and nucleotide coenzymes (important in intermediary metabolism), the nature of the genetic material and biological synthesis of proteins, formulation of the problem of the genetic code, and perspectives on bioenergetics.The selected papers illustrate the developments of the chemical synthesis of nucleotides and nucleotide coenzymes of ribo- and deoxy-ribo-polynucleotides (RNA, DNA), of the total synthesis of genes in the laboratory, and principles for gene amplification (PCR). Another major section covers studies of enzymes that degrade nucleic acids, the structure of transfer RNA and its role in protein synthesis, and the author's work on the elucidation of the genetic code. Finally, there are descriptions of the studies on biological membranes and the membrane protein bacteriorhodopsin, a biological proton pump. These studies elucidated the mechanism of proton translocation, which is central to bioenergetics.
Book Synopsis Fred Sanger - Double Nobel Laureate by : George G. Brownlee
Download or read book Fred Sanger - Double Nobel Laureate written by George G. Brownlee and published by Cambridge University Press. This book was released on 2020-04-02 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.
Book Synopsis The Discovery of Insulin by : Michael Bliss
Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.
Download or read book International Books in Print written by and published by . This book was released on 1998 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Frederick Sanger by : Joe S. Jeffers
Download or read book Frederick Sanger written by Joe S. Jeffers and published by Springer. This book was released on 2017-03-14 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
Download or read book Forthcoming Books written by Rose Arny and published by . This book was released on 2002 with total page 1752 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bulletin of the Atomic Scientists by :
Download or read book Bulletin of the Atomic Scientists written by and published by . This book was released on 2008 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bibliographic Guide to East Asian Studies 1996 by : G K HALL
Download or read book Bibliographic Guide to East Asian Studies 1996 written by G K HALL and published by Macmillan Reference USA. This book was released on 1997-07 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cumulative Book Index written by and published by . This book was released on 1997 with total page 2312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.
Book Synopsis Basic Science Methods for Clinical Researchers by : Morteza Jalali
Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
Book Synopsis The Margaret Sanger Papers by : Margaret Sanger
Download or read book The Margaret Sanger Papers written by Margaret Sanger and published by . This book was released on 1996 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Nobel Fellow on Every Floor by : John Finch
Download or read book A Nobel Fellow on Every Floor written by John Finch and published by Icon Books. This book was released on 2024-06-07 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Cambridge in the 1950s, several research groups funded by the Medical Research Council were producing exciting results. In the Biochemistry Department, Sanger determined the amino acid sequence of insulin, and was awarded a Nobel Prize for this in 1958. At the Cavendish Laboratory, in the MRC Unit for the Study of the Molecular Structure of Biological Systems, Watson and Crick solved the structure of DNA, and Perutz and Kendrew produced the first three-dimensional maps of protein structures – haemoglobin and myoglobin – for which all four were later awarded Nobel Prizes. This made it timely to create, in 1962, a new Laboratory of Molecular Biology in Cambridge by amalgamating these groups with other MRC-funded groups from London. The Laboratory has become one of the most successful in its field, and the number of Nobel Prizes awarded over the years to scientists at LMB has risen to thirteen. This book follows the development of LMB, through the people who moved into the new Laboratory and their research. It describes events and personalities that have given the Laboratory a friendly, family atmosphere, while continuing to be scientifically productive.
Book Synopsis Biochemistry: A Very Short Introduction by : Mark Lorch
Download or read book Biochemistry: A Very Short Introduction written by Mark Lorch and published by Oxford University Press. This book was released on 2021-05-27 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Very Short Introductions: Brilliant, Sharp, Inspiring From the simplest bacteria to humans, all living things are composed of cells of one type or another, all of which have fundamentally the same chemistry. This chemistry must provide mechanisms that allow cells to interact with the external world, a means to power the cell, machinery to carry out varied processes within the cell, a structure within which everything runs, and also governance through a web of interlocking chemical reactions. Biochemistry is the study of those reactions, the molecules that are created, manipulated, and destroyed as a result of them, and the massive macromolecules (such as DNA, cytoskeletons, proteins and carbohydrates) that form the chemical machinery and structures on which these biochemical reactions take place. It didn't take long for an understanding of the chemistry of life to turn into a desire to manipulate it. Drugs and therapies all aim to modify biochemical processes for good or ill: Penicillin, derived from mould, stops bacteria making their cell walls. Aspirin, with its origins in willow bark, inhibits enzymes involved in inflammatory responses. A few nanograms of botulinum toxin (botox), can kill by preventing the release of neurotransmitters from the ends of nerves and so leads to paralysis and death, or give a wrinkle free forehead (if administered in very tiny quantities).This Very Short Introduction discusses the key concepts of biochemistry, as well as the historical figures in the field and the molecules they studied, before considering the current science and innovations in the field, and the interaction between biochemistry, biotechnology, and synthetic biology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Book Synopsis A Short History of Medical Genetics by : Peter S. Harper
Download or read book A Short History of Medical Genetics written by Peter S. Harper and published by Oxford University Press. This book was released on 2008 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book traces the development of genetics in medicine from the first descriptions of inherited diseases more than 300 years ago to the new applications resulting from mapping and sequencing the human genome. It follows both the scientific and the medical advances, focusing especially on those of the past 50 years, which have seen the field of medical genetics emerge as one of the foremost and most rapidly changing medical specialties, now influencing the whole of medicine. It also examines the ethical challenges faced by those working in the field, and describes some of the past disasters that have resulted from these being ignored, notably the abuses of eugenics and the catastrophic destruction of genetics in Soviet Russia. This is the first book of its kind; it is clearly and simply written, and will be valuable to all those who have an interest or concern in the development of medical genetics, as well as those actually working in the field. Historians and social scientists will likewise find this book an important foundation for future detailed studies, which are urgently needed."--BOOK JACKET.
Book Synopsis The End of Racism by : Dinesh D'Souza
Download or read book The End of Racism written by Dinesh D'Souza and published by Simon and Schuster. This book was released on 1996-09-30 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first conprehensive inquiry into the history, nature and ultimate meaning of racism.
Book Synopsis Molecules and Life by : Joseph Stewart Fruton
Download or read book Molecules and Life written by Joseph Stewart Fruton and published by John Wiley & Sons. This book was released on 1972 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
