Science Of Synthesis Multicomponent Reactions Vol 1

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Science of Synthesis: Multicomponent Reactions Vol. 1

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Author : Thomas J. J. Müller
Publisher : Thieme
ISBN 13 : 313176581X
Total Pages : 999 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: Multicomponent Reactions Vol. 1 by : Thomas J. J. Müller

Download or read book Science of Synthesis: Multicomponent Reactions Vol. 1 written by Thomas J. J. Müller and published by Thieme. This book was released on 2014-05-14 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving a Carbonyl Compound as Electrophilic Component" covers the following topics: Biginelli Reaction Strecker Reaction Hantzsch Pyridine Synthesis Mannich Reaction Petasis Reaction Willgerodt-Kindler Reaction Kabachnik-Fields Reaction Passerini Reaction Ugi Reaction Gewald Reaction

Multicomponent Reactions in Organic Synthesis

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Author : Jieping Zhu
Publisher : John Wiley & Sons
ISBN 13 : 3527332375
Total Pages : 512 pages
Book Rating : 4.5/5 (273 download)

Book Synopsis Multicomponent Reactions in Organic Synthesis by : Jieping Zhu

Download or read book Multicomponent Reactions in Organic Synthesis written by Jieping Zhu and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a "who's who" in multicomponent reaction chemistry, this is definitely a must-have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies.

Multicomponent Reactions

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Author : Raquel P. Herrera
Publisher : John Wiley & Sons
ISBN 13 : 1118863976
Total Pages : 528 pages
Book Rating : 4.1/5 (188 download)

Book Synopsis Multicomponent Reactions by : Raquel P. Herrera

Download or read book Multicomponent Reactions written by Raquel P. Herrera and published by John Wiley & Sons. This book was released on 2015-04-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a dynamic aspect of organic chemistry, this bookdescribes synthetic strategies and applications for multicomponentreactions – including key routes for synthesizing complexmolecules. • Illustrates the crucial role and theimportant utility of multicomponent reactions (MCRs) to organicsyntheses • Compiles novel and efficient syntheticmulticomponent procedures to give readers a complete picture ofthis class of organic reactions • Helps readers to design efficient andpractical transformations using multicomponent reactionstrategies • Describes reaction background,applications to synthesize complex molecules and drugs, andreaction mechanisms

Multicomponent Reactions

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Author : Thomas J. J. Müller
Publisher : Thieme/Houben-Weyl Series
ISBN 13 : 9783131728616
Total Pages : 652 pages
Book Rating : 4.7/5 (286 download)

Book Synopsis Multicomponent Reactions by : Thomas J. J. Müller

Download or read book Multicomponent Reactions written by Thomas J. J. Müller and published by Thieme/Houben-Weyl Series. This book was released on 2014 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This two volume reference work on multicomponent reactions has been designed to summarized critically the major experimentally relevant synthetic processes in a highly dynamic field, which is of particular interest to synthetic practitioners in both academia and industry" --Back cover.

Multicomponent Reactions, Workbench Edition

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Author : Thomas J. J. Müller
Publisher : Thieme Chemistry
ISBN 13 : 9783131765611
Total Pages : 0 pages
Book Rating : 4.7/5 (656 download)

Book Synopsis Multicomponent Reactions, Workbench Edition by : Thomas J. J. Müller

Download or read book Multicomponent Reactions, Workbench Edition written by Thomas J. J. Müller and published by Thieme Chemistry. This book was released on 2014-03-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes Science of Synthesis: Multicomponent Reactions critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. The following topics are covered: Biginelli Reaction, Strecker Reaction, Hantzsch Pyridine Synthesis, Mannich Reaction, Petasis Reaction, Willgerodt-Kindler Reaction, Kabachnik-Fields Reaction, Passerini Reaction, Ugi Reaction, Gewald Reaction (Vol. 1); Michael Additions, Wittig Reactions, Cycloadditions, Reactions Involving an a,-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles, Reactions with Cycloaddition as the Key Step, Boron-Mediated Multicomponent Reactions, Silicon-Mediated Multicomponent Reactions, Free-Radical Mediated Multicomponent Reactions, Metal-Mediated Multicomponent Reactions (Vol. 2).

Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis

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Author : E. Fernández
Publisher : Thieme
ISBN 13 : 3132429732
Total Pages : 582 pages
Book Rating : 4.1/5 (324 download)

Book Synopsis Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis by : E. Fernández

Download or read book Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis written by E. Fernández and published by Thieme. This book was released on 2020-05-22 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.

Science of Synthesis: Multicomponent Reactions Vol. 2

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Author :
Publisher : Thieme
ISBN 13 : 3131766018
Total Pages : 926 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: Multicomponent Reactions Vol. 2 by :

Download or read book Science of Synthesis: Multicomponent Reactions Vol. 2 written by and published by Thieme. This book was released on 2014-05-14 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component" covers the following topics: Michael Additions Wittig Reactions Cycloadditions Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles Reactions with Cycloaddition as the Key Step Boron-Mediated Multicomponent Reactions Silicon-Mediated Multicomponent Reactions Free-Radical Mediated Multicomponent Reactions Metal-Mediated Multicomponent Reactions

Multicomponent Reactions

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Author : K.L. Ameta, Ph.D.
Publisher : CRC Press
ISBN 13 : 1315352737
Total Pages : 598 pages
Book Rating : 4.3/5 (153 download)

Book Synopsis Multicomponent Reactions by : K.L. Ameta, Ph.D.

Download or read book Multicomponent Reactions written by K.L. Ameta, Ph.D. and published by CRC Press. This book was released on 2017-09-20 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Science of Synthesis: Metal-Catalyzed Cyclization Reactions

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Author : Shuanhu Gao
Publisher : Thieme
ISBN 13 : 3131999012
Total Pages : 914 pages
Book Rating : 4.1/5 (319 download)

Book Synopsis Science of Synthesis: Metal-Catalyzed Cyclization Reactions by : Shuanhu Gao

Download or read book Science of Synthesis: Metal-Catalyzed Cyclization Reactions written by Shuanhu Gao and published by Thieme. This book was released on 2016-12-14 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in metal-catalyzed reactions, especially cyclizations, have dramatically improved the efficiency of organic synthesis over the last three decades. To date these transformations are widely used in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: Metal-Catalyzed Cyclization Reactions" presents the most commonly used and significant metal-catalyzed reactions for modern organic synthesis. The basic principles, the current state of the art, scope, limitations, and mechanism of these reactions are also discussed. Typical examples of target synthesis are provided to help inspire further applications. Volume 1 covers intramolecular coupling reactions (including Heck reactions), intramolecular allylations, and cyclopropane and cyclopropene ring openings. Also included are cyclization reactions of alkenes, alkynes, and allenes, cycloisomerizations, and intramolecular C-N and C-O bond formation.

Multicomponent Reactions towards Heterocycles

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Author : Erik Van der Eycken
Publisher : John Wiley & Sons
ISBN 13 : 3527349081
Total Pages : 626 pages
Book Rating : 4.5/5 (273 download)

Book Synopsis Multicomponent Reactions towards Heterocycles by : Erik Van der Eycken

Download or read book Multicomponent Reactions towards Heterocycles written by Erik Van der Eycken and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 1

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Author : Piet W.N.M. van Leeuwen
Publisher : Thieme
ISBN 13 : 3131765313
Total Pages : 954 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 1 by : Piet W.N.M. van Leeuwen

Download or read book Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 1 written by Piet W.N.M. van Leeuwen and published by Thieme. This book was released on 2014-05-14 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.

Multi-component Reactions in Molecular Diversity

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Author : Jean-Philippe Goddard
Publisher : John Wiley & Sons
ISBN 13 : 1786305119
Total Pages : 198 pages
Book Rating : 4.7/5 (863 download)

Book Synopsis Multi-component Reactions in Molecular Diversity by : Jean-Philippe Goddard

Download or read book Multi-component Reactions in Molecular Diversity written by Jean-Philippe Goddard and published by John Wiley & Sons. This book was released on 2020-04-28 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: While very useful for studying syntheses of molecular diversity, multi-component reactions also offer rapid access to a variety of complex molecules that are relevant for biological applications. Multi-component Reactions in Molecular Diversity analyzes these reactions, whether they are realized by organometallic, ionic or even radical processes. It highlights popular methods based on monotype reactions (cascade, tandem, domino) and their efficiency and academic industrial domain are illustrated. This book also investigates the most efficient ways to prepare complex molecules. Multi-component reactions are in tune with the concepts of atom and steps economy, which are of prior importance in all the reported processes ? from the laboratory to the pilot scale. The essential criteria for green chemistry are also examined in the book in detail.

Science of Synthesis: Multicomponent Reactions Vol. 2

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Author : Thomas J. J. Müller
Publisher : Thieme
ISBN 13 : 3131765917
Total Pages : 632 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: Multicomponent Reactions Vol. 2 by : Thomas J. J. Müller

Download or read book Science of Synthesis: Multicomponent Reactions Vol. 2 written by Thomas J. J. Müller and published by Thieme. This book was released on 2014-05-14 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component" covers the following topics: Michael Additions Wittig Reactions Cycloadditions Reactions Involving an alpha,beta-Unsaturated Carbonyl Compound as Electrophilic Component with Electron-Deficient Alkynes as Electrophiles Reactions with Cycloaddition as the Key Step Boron-Mediated Multicomponent Reactions Silicon-Mediated Multicomponent Reactions Free-Radical Mediated Multicomponent Reactions Metal-Mediated Multicomponent Reactions

Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 2

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Author : Piet W.N.M. van Leeuwen
Publisher : Thieme
ISBN 13 : 3131765518
Total Pages : 780 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 2 by : Piet W.N.M. van Leeuwen

Download or read book Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 2 written by Piet W.N.M. van Leeuwen and published by Thieme. This book was released on 2014-05-14 with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.

Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 1

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Author : Kurt Faber
Publisher : Thieme
ISBN 13 : 3131766212
Total Pages : 997 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 1 by : Kurt Faber

Download or read book Science of Synthesis: Biocatalysis in Organic Synthesis Vol. 1 written by Kurt Faber and published by Thieme. This book was released on 2015-03-11 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 1 begins with chapters discussing the historical development of the field, sources of enzymes and appropriate selection of catalysts, and general strategies employed in biocatalysis. This is followed by reviews of the biocatalytic hydrolysis of various substrates. The volume concludes with chapters devoted to biocatalytic isomerizations, and the synthesis of glycosides.

Science of Synthesis: Catalytic Transformations via C-H Activation Vol. 1

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Author : Jin-Quan Yu
Publisher : Thieme
ISBN 13 : 3131766816
Total Pages : 756 pages
Book Rating : 4.1/5 (317 download)

Book Synopsis Science of Synthesis: Catalytic Transformations via C-H Activation Vol. 1 by : Jin-Quan Yu

Download or read book Science of Synthesis: Catalytic Transformations via C-H Activation Vol. 1 written by Jin-Quan Yu and published by Thieme. This book was released on 2016-05-23 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: The reference work Science of Synthesis: Catalytic Transformations via C-H Activation covers the state of the art in C-H activation chemistry. Experts in the field present the best synthetic methods including typical or general experimental procedures. As such, this two volume set can serve as both a basis for the practical application of the techniques discussed, and as an educational resource to lay the foundations for future research. Volume 1 concerns the formation of C-C bonds by both arene and hetarene C-H activation. For the arenes the material is subdivided into arylation (using palladium(0), palladium(II)/palladium(IV), palladium(II), and ruthenium(II) catalysts), vinylation (using various palladium and ruthenium(III) catalysts), and alkylation (using various metal catalysts in combination with either functionalized alkanes or alkenes). For the hetarenes, the related coupling strategies are covered as a single topic using a variety of metal catalysts and coupling partners.

Multicomponent Reactions

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Author :
Publisher :
ISBN 13 :
Total Pages : 507 pages
Book Rating : 4.:/5 (914 download)

Book Synopsis Multicomponent Reactions by :

Download or read book Multicomponent Reactions written by and published by . This book was released on 2015 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: