Analysis of Clinical Trials Using SAS

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Publisher : SAS Institute
ISBN 13 : 1635261449
Total Pages : 455 pages
Book Rating : 4.6/5 (352 download)

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Book Synopsis Analysis of Clinical Trials Using SAS by : Alex Dmitrienko

Download or read book Analysis of Clinical Trials Using SAS written by Alex Dmitrienko and published by SAS Institute. This book was released on 2017-07-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Clinical Trials Using SAS®: A Practical Guide, Second Edition bridges the gap between modern statistical methodology and real-world clinical trial applications. Tutorial material and step-by-step instructions illustrated with examples from actual trials serve to define relevant statistical approaches, describe their clinical trial applications, and implement the approaches rapidly and efficiently using the power of SAS. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials. Commonly used methods are covered, including dose-escalation and dose-finding methods that are applied in Phase I and Phase II clinical trials, as well as important trial designs and analysis strategies that are employed in Phase II and Phase III clinical trials, such as multiplicity adjustment, data monitoring, and methods for handling incomplete data. This book also features recommendations from clinical trial experts and a discussion of relevant regulatory guidelines. This new edition includes more examples and case studies, new approaches for addressing statistical problems, and the following new technological updates: SAS procedures used in group sequential trials (PROC SEQDESIGN and PROC SEQTEST) SAS procedures used in repeated measures analysis (PROC GLIMMIX and PROC GEE) macros for implementing a broad range of randomization-based methods in clinical trials, performing complex multiplicity adjustments, and investigating the design and analysis of early phase trials (Phase I dose-escalation trials and Phase II dose-finding trials) Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience and the ready-to-use SAS macros compiled in this book.

SAS Software

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Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis SAS Software by : SAS Institute

Download or read book SAS Software written by SAS Institute and published by . This book was released on 1993 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Common Statistical Methods for Clinical Research with SAS Examples, Third Edition

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Publisher : SAS Institute
ISBN 13 : 1607644258
Total Pages : 553 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Common Statistical Methods for Clinical Research with SAS Examples, Third Edition by : Glenn Walker

Download or read book Common Statistical Methods for Clinical Research with SAS Examples, Third Edition written by Glenn Walker and published by SAS Institute. This book was released on 2010-02-15 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glenn Walker and Jack Shostak's Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is a thoroughly updated edition of the popular introductory statistics book for clinical researchers. This new edition has been extensively updated to include the use of ODS graphics in numerous examples as well as a new emphasis on PROC MIXED. Straightforward and easy to use as either a text or a reference, the book is full of practical examples from clinical research to illustrate both statistical and SAS methodology. Each example is worked out completely, step by step, from the raw data. Common Statistical Methods for Clinical Research with SAS Examples, Third Edition, is an applications book with minimal theory. Each section begins with an overview helpful to nonstatisticians and then drills down into details that will be valuable to statistical analysts and programmers. Further details, as well as bonus information and a guide to further reading, are presented in the extensive appendices. This text is a one-source guide for statisticians that documents the use of the tests used most often in clinical research, with assumptions, details, and some tricks--all in one place. This book is part of the SAS Press program.

Clinical Trial Data Analysis Using R and SAS

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Publisher : CRC Press
ISBN 13 : 1351651145
Total Pages : 385 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Clinical Trial Data Analysis Using R and SAS by : Ding-Geng (Din) Chen

Download or read book Clinical Trial Data Analysis Using R and SAS written by Ding-Geng (Din) Chen and published by CRC Press. This book was released on 2017-06-01 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it ...The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."—Journal of Statistical Software Clinical Trial Data Analysis Using R and SAS, Second Edition provides a thorough presentation of biostatistical analyses of clinical trial data with step-by-step implementations using R and SAS. The book’s practical, detailed approach draws on the authors’ 30 years’ experience in biostatistical research and clinical development. The authors develop step-by-step analysis code using appropriate R packages and functions and SAS PROCS, which enables readers to gain an understanding of the analysis methods and R and SAS implementation so that they can use these two popular software packages to analyze their own clinical trial data. What’s New in the Second Edition Adds SAS programs along with the R programs for clinical trial data analysis. Updates all the statistical analysis with updated R packages. Includes correlated data analysis with multivariate analysis of variance. Applies R and SAS to clinical trial data from hypertension, duodenal ulcer, beta blockers, familial andenomatous polyposis, and breast cancer trials. Covers the biostatistical aspects of various clinical trials, including treatment comparisons, time-to-event endpoints, longitudinal clinical trials, and bioequivalence trials.

Pharmaceutical Statistics Using SAS

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Publisher : SAS Institute
ISBN 13 : 1629590304
Total Pages : 464 pages
Book Rating : 4.6/5 (295 download)

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Book Synopsis Pharmaceutical Statistics Using SAS by : Alex Dmitrienko, Ph.D.

Download or read book Pharmaceutical Statistics Using SAS written by Alex Dmitrienko, Ph.D. and published by SAS Institute. This book was released on 2007-02-07 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.

Validating Clinical Trial Data Reporting with SAS

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Publisher : SAS Institute
ISBN 13 : 1599941287
Total Pages : 229 pages
Book Rating : 4.5/5 (999 download)

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Book Synopsis Validating Clinical Trial Data Reporting with SAS by : Carol I. Matthews

Download or read book Validating Clinical Trial Data Reporting with SAS written by Carol I. Matthews and published by SAS Institute. This book was released on 2008 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This indispensable guide focuses on validating programs written to support the clinical trial process from after the data collection stage to generating reports and submitting data and output to the Food and Drug Administration.

Data Analysis Using SAS

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Publisher : SAGE Publications
ISBN 13 : 1483342794
Total Pages : 641 pages
Book Rating : 4.4/5 (833 download)

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Book Synopsis Data Analysis Using SAS by : C.Y. Joanne Peng

Download or read book Data Analysis Using SAS written by C.Y. Joanne Peng and published by SAGE Publications. This book was released on 2008-08-28 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data Analysis Using SAS offers a comprehensive core text focused on key concepts and techniques in quantitative data analysis using the most current SAS commands and programming language. The coverage of the text is more evenly balanced among statistical analysis, SAS programming, and data/file management than any available text on the market. It provides students with a hands-on, exercise-heavy method for learning basic to intermediate SAS commands while understanding how to apply statistics and reasoning to real-world problems. Designed to be used in order of teaching preference by instructor, the book is comprised of two primary sections: the first half of the text instructs students in techniques for data and file managements such as concatenating and merging files, conditional or repetitive processing of variables, and observations. The second half of the text goes into great depth on the most common statistical techniques and concepts - descriptive statistics, correlation, analysis of variance, and regression - used to analyze data in the social, behavioral, and health sciences using SAS commands. A student study comes replete with a multitude of computer programs, their output, specific details on how to check assumptions, as well as all data sets used in the book. Data Analysis Using SAS is a complete resource for Data Analysis I and II, Statistics I and II, Quantitative Reasoning, and SAS Programming courses across the social and behavioral sciences and health - especially those that carry a lab component.

Modern Approaches to Clinical Trials Using SAS

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Publisher : SAS Institute
ISBN 13 : 1629600822
Total Pages : 496 pages
Book Rating : 4.6/5 (296 download)

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Book Synopsis Modern Approaches to Clinical Trials Using SAS by : Sandeep Menon

Download or read book Modern Approaches to Clinical Trials Using SAS written by Sandeep Menon and published by SAS Institute. This book was released on 2015-12-09 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the tools you need to use SAS® in clinical trial design! Unique and multifaceted, Modern Approaches to Clinical Trials Using SAS: Classical, Adaptive, and Bayesian Methods, edited by Sandeep M. Menon and Richard C. Zink, thoroughly covers several domains of modern clinical trial design: classical, group sequential, adaptive, and Bayesian methods that are applicable to and widely used in various phases of pharmaceutical development. Written for biostatisticians, pharmacometricians, clinical developers, and statistical programmers involved in the design, analysis, and interpretation of clinical trials, as well as students in graduate and postgraduate programs in statistics or biostatistics, the book touches on a wide variety of topics, including dose-response and dose-escalation designs; sequential methods to stop trials early for overwhelming efficacy, safety, or futility; Bayesian designs that incorporate historical data; adaptive sample size re-estimation; adaptive randomization to allocate subjects to more effective treatments; and population enrichment designs. Methods are illustrated using clinical trials from diverse therapeutic areas, including dermatology, endocrinology, infectious disease, neurology, oncology, and rheumatology. Individual chapters are authored by renowned contributors, experts, and key opinion leaders from the pharmaceutical/medical device industry or academia. Numerous real-world examples and sample SAS code enable users to readily apply novel clinical trial design and analysis methodologies in practice.

The Handbook of Software for Engineers and Scientists

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Publisher : CRC Press
ISBN 13 : 9780849325304
Total Pages : 1580 pages
Book Rating : 4.3/5 (253 download)

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Book Synopsis The Handbook of Software for Engineers and Scientists by : Paul W. Ross

Download or read book The Handbook of Software for Engineers and Scientists written by Paul W. Ross and published by CRC Press. This book was released on 1995-10-25 with total page 1580 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Software for Engineers and Scientists is a single-volume, ready reference for the practicing engineer and scientist in industry, government, and academia as well as the novice computer user. It provides the most up-to-date information in a variety of areas such as common platforms and operating systems, applications programs, networking, and many other problem-solving tools necessary to effectively use computers on a daily basis. Specific platforms and environments thoroughly discussed include MS-DOS®, Microsoft® WindowsTM, the Macintosh® and its various systems, UNIXTM, DEC VAXTM, IBM® mainframes, OS/2®, WindowsTM NT, and NeXTSTEPTM. Word processing, desktop publishing, spreadsheets, databases, integrated packages, computer presentation systems, groupware, and a number of useful utilities are also covered. Several extensive sections in the book are devoted to mathematical and statistical software. Information is provided on circuits and control simulation programs, finite element tools, and solid modeling tools. Additional coverage is included on data communications and networking. Many appendices at the end of the book provide useful supplemental information, such as ASCII codes, RS-232 parallel port and pinout information, and ANSI escape sequences. This valuable resource handbook brings together a wide variety of topics and offers a wealth of information at the reader's fingertips.

Health Care Data and the SAS System

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Publisher : SAS Press
ISBN 13 : 9781580258654
Total Pages : 0 pages
Book Rating : 4.2/5 (586 download)

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Book Synopsis Health Care Data and the SAS System by : Marge Scerbo

Download or read book Health Care Data and the SAS System written by Marge Scerbo and published by SAS Press. This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: New and experienced SAS programmers and analysts working in health care data analysis will find this book invaluable in their daily professional life. A terrific primer for new health care analysts and a reference for long-time practitioners, this book defines the types of health care data and explores a wide range of tasks, including reading, validating, and manipulating the health care data, and producing reports.

Risk-Based Monitoring and Fraud Detection in Clinical Trials Using JMP and SAS

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Publisher : SAS Institute
ISBN 13 : 1629592331
Total Pages : 387 pages
Book Rating : 4.6/5 (295 download)

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Book Synopsis Risk-Based Monitoring and Fraud Detection in Clinical Trials Using JMP and SAS by : Richard C. Zink

Download or read book Risk-Based Monitoring and Fraud Detection in Clinical Trials Using JMP and SAS written by Richard C. Zink and published by SAS Institute. This book was released on 2014-07-01 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improve efficiency while reducing costs in clinical trials with centralized monitoring techniques using JMP and SAS. International guidelines recommend that clinical trial data should be actively reviewed or monitored; the well-being of trial participants and the validity and integrity of the final analysis results are at stake. Traditional interpretation of this guidance for pharmaceutical trials has led to extensive on-site monitoring, including 100% source data verification. On-site review is time consuming, expensive (estimated at up to a third of the cost of a clinical trial), prone to error, and limited in its ability to provide insight for data trends across time, patients, and clinical sites. In contrast, risk-based monitoring (RBM) makes use of central computerized review of clinical trial data and site metrics to determine if and when clinical sites should receive more extensive quality review or intervention. Risk-Based Monitoring and Fraud Detection in Clinical Trials Using JMP and SAS presents a practical implementation of methodologies within JMP Clinical for the centralized monitoring of clinical trials. Focused on intermediate users, this book describes analyses for RBM that incorporate and extend the recommendations of TransCelerate Biopharm Inc., methods to detect potential patient-or investigator misconduct, snapshot comparisons to more easily identify new or modified data, and other novel visual and analytical techniques to enhance safety and quality reviews. Further discussion highlights recent regulatory guidance documents on risk-based approaches, addresses the requirements for CDISC data, and describes methods to supplement analyses with data captured external to the study database. Given the interactive, dynamic, and graphical nature of JMP Clinical, any individual from the clinical trial team - including clinicians, statisticians, data managers, programmers, regulatory associates, and monitors - can make use of this book and the numerous examples contained within to streamline, accelerate, and enrich their reviews of clinical trial data. The analytical methods described in Risk-Based Monitoring and Fraud Detection in Clinical Trials Using JMP and SAS enable the clinical trial team to take a proactive approach to data quality and safety to streamline clinical development activities and address shortcomings while the study is ongoing. This book is part of the SAS Press

Revival: The Handbook of Software for Engineers and Scientists (1995)

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Author :
Publisher : CRC Press
ISBN 13 : 1351357050
Total Pages : 1781 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Revival: The Handbook of Software for Engineers and Scientists (1995) by : Paul W Ross

Download or read book Revival: The Handbook of Software for Engineers and Scientists (1995) written by Paul W Ross and published by CRC Press. This book was released on 2018-05-04 with total page 1781 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Software for Engineers and Scientists is a single-volume, ready reference for the practicing engineer and scientist in industry, government, and academia as well as the novice computer user. It provides the most up-to-date information in a variety of areas such as common platforms and operating systems, applications programs, networking, and many other problem-solving tools necessary to effectively use computers on a daily basis. Specific platforms and environments thoroughly discussed include MS-DOS®, Microsoft® WindowsTM, the Macintosh® and its various systems, UNIXTM, DEC VAXTM, IBM® mainframes, OS/2®, WindowsTM NT, and NeXTSTEPTM. Word processing, desktop publishing, spreadsheets, databases, integrated packages, computer presentation systems, groupware, and a number of useful utilities are also covered. Several extensive sections in the book are devoted to mathematical and statistical software. Information is provided on circuits and control simulation programs, finite element tools, and solid modeling tools.

SAS/QC Software

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Publisher :
ISBN 13 :
Total Pages : 876 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis SAS/QC Software by : SAS Institute

Download or read book SAS/QC Software written by SAS Institute and published by . This book was released on 1995 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CAPABILITY procedure; The CUSUM procedure; The FACTEX procedure; The ISHIKAWA procedure; The MACONTROL procedure; The OPTEC procedure; The PARETO procedure; The SHEWHART procedure .

Analysis of Observational Health Care Data Using SAS

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Publisher : SAS Press
ISBN 13 : 9781607642275
Total Pages : 0 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Analysis of Observational Health Care Data Using SAS by : Douglas E. Faries

Download or read book Analysis of Observational Health Care Data Using SAS written by Douglas E. Faries and published by SAS Press. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.

SAS/QC Software

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Publisher :
ISBN 13 :
Total Pages : 862 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis SAS/QC Software by :

Download or read book SAS/QC Software written by and published by . This book was released on 1995 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Learning SAS by Example

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Publisher : SAS Institute
ISBN 13 : 1635266564
Total Pages : 553 pages
Book Rating : 4.6/5 (352 download)

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Book Synopsis Learning SAS by Example by : Ron Cody

Download or read book Learning SAS by Example written by Ron Cody and published by SAS Institute. This book was released on 2018-07-03 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to program SAS by example! Learning SAS by Example, A Programmer’s Guide, Second Edition, teaches SAS programming from very basic concepts to more advanced topics. Because most programmers prefer examples rather than reference-type syntax, this book uses short examples to explain each topic. The second edition has brought this classic book on SAS programming up to the latest SAS version, with new chapters that cover topics such as PROC SGPLOT and Perl regular expressions. This book belongs on the shelf (or e-book reader) of anyone who programs in SAS, from those with little programming experience who want to learn SAS to intermediate and even advanced SAS programmers who want to learn new techniques or identify new ways to accomplish existing tasks. In an instructive and conversational tone, author Ron Cody clearly explains each programming technique and then illustrates it with one or more real-life examples, followed by a detailed description of how the program works. The text is divided into four major sections: Getting Started, DATA Step Processing, Presenting and Summarizing Your Data, and Advanced Topics. Subjects addressed include Reading data from external sources Learning details of DATA step programming Subsetting and combining SAS data sets Understanding SAS functions and working with arrays Creating reports with PROC REPORT and PROC TABULATE Getting started with the SAS macro language Leveraging PROC SQL Generating high-quality graphics Using advanced features of user-defined formats and informats Restructuring SAS data sets Working with multiple observations per subject Getting started with Perl regular expressions You can test your knowledge and hone your skills by solving the problems at the end of each chapter.

SAS Certified Specialist Prep Guide

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Publisher : SAS Institute
ISBN 13 : 1642951765
Total Pages : 665 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis SAS Certified Specialist Prep Guide by : SAS Institute

Download or read book SAS Certified Specialist Prep Guide written by SAS Institute and published by SAS Institute. This book was released on 2019-02-11 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: The SAS® Certified Specialist Prep Guide: Base Programming Using SAS® 9.4 prepares you to take the new SAS 9.4 Base Programming -- Performance-Based Exam. This is the official guide by the SAS Global Certification Program. This prep guide is for both new and experienced SAS users, and it covers all the objectives that are tested on the exam. New in this edition is a workbook whose sample scenarios require you to write code to solve problems and answer questions. Answers for the chapter quizzes and solutions for the sample scenarios in the workbook are included. You will also find links to exam objectives, practice exams, and other resources such as the Base SAS® glossary and a list of practice data sets. Major topics include importing data, creating and modifying SAS data sets, and identifying and correcting both data syntax and programming logic errors. All exam topics are covered in these chapters: Setting Up Practice Data Basic Concepts Accessing Your Data Creating SAS Data Sets Identifying and Correcting SAS Language Errors Creating Reports Understanding DATA Step Processing BY-Group Processing Creating and Managing Variables Combining SAS Data Sets Processing Data with DO Loops SAS Formats and Informats SAS Date, Time, and Datetime Values Using Functions to Manipulate Data Producing Descriptive Statistics Creating Output Practice Programming Scenarios (Workbook)