Role Of Nonlinear Dynamics In Endocrine Feedback

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Role of Nonlinear Dynamics in Endocrine Feedback

Author : Chinmoy K. Bose
Publisher : Nova Biomedical Books
ISBN 13 : 9781607419488
Total Pages : 0 pages
Book Rating : 4.4/5 (194 download)

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Book Synopsis Role of Nonlinear Dynamics in Endocrine Feedback by : Chinmoy K. Bose

Download or read book Role of Nonlinear Dynamics in Endocrine Feedback written by Chinmoy K. Bose and published by Nova Biomedical Books. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine feedback system may not be appreciated by conventional hormone level estimation at a single point of time. Our body also needs to be looked at as a dynamical system, a dissipative structure. Specifically, the information processing at the neuroendocrine level must be guided by a science that is not random but deterministic. For sustenance of life body environ must always (at the present moment) balance itself delicately and relentlessly. In this dynamical system, feedback control will essentially be mathematical control that has to be understood in the light of physical control theory. Whatever goes around inside the body must be originating from chemical reactions, but factors controlling the nature and rate and limit of those reactions are multi-relation oriented. The outcome of such relationship is not limited to linear reactions but dependent on some "non-material entity", like balancing while cycling or walking on a rope. This non-material entity is described as "feedback" relationship. This book tries to elucidate how and why such kind of relationship must be understood in order to know this reportedly simple subject of endocrine feedback.

Feedback Control in Systems Biology

Author : Carlo Cosentino
Publisher : CRC Press
ISBN 13 : 1439816905
Total Pages : 298 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Feedback Control in Systems Biology by : Carlo Cosentino

Download or read book Feedback Control in Systems Biology written by Carlo Cosentino and published by CRC Press. This book was released on 2011-10-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.

Analysis of Physiological Systems

Author : Vasilis Marmarelis
Publisher : Springer Science & Business Media
ISBN 13 : 1461339707
Total Pages : 495 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Analysis of Physiological Systems by : Vasilis Marmarelis

Download or read book Analysis of Physiological Systems written by Vasilis Marmarelis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: In studying physiological systems bioscientists are continually faced with the problem of providing descriptions of cause-effect relationships. This task is usually carried out through the performance of stimulus-response experiments. In the past, the design of such experiments has been ad hoc, incomplete, and certainly inefficient. Worse yet, bioscientists have failed to take advantage of advances in fields directly related to their problems (specifically, advances in the area of systems analysis). The raison d'etre of this book is to rectify this deficiency by providing the physiologist with methodological tools that will be useful to him or her in everyday labora tory encounters with physiological systems. The book was written so that it would be practical, useful, and up-to date. With this in mind, parts of it give step-by-step descriptions of in the laboratory. It is hoped that this systematic procedures to be followed will increase the usefulness of the book to the average research physiologist and, perhaps, reduce the need for in-depth knowledge of some of the associated mathematics. Even though the material deals with state-of-the art techniques in systems and signal analysis, the mathematical level has been kept low so as to be comprehensible to the average physiologist with no extensive training in mathematics. To this end, mathematical rigor is often sacrificed readily to intuitive simple arguments.

Vertebrate Endocrinology

Author : David O. Norris
Publisher : Academic Press
ISBN 13 : 0123964652
Total Pages : 599 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Vertebrate Endocrinology by : David O. Norris

Download or read book Vertebrate Endocrinology written by David O. Norris and published by Academic Press. This book was released on 2013-05-04 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vertebrate Endocrinology represents more than just a treatment of the endocrine system-it integrates hormones with other chemical bioregulatory agents not classically included with the endocrine system. It provides a complete overview of the endocrine system of vertebrates by first emphasizing the mammalian system as the basis of most terminology and understanding of endocrine mechanisms and then applies that to non-mammals. The serious reader will gain both an understanding of the intricate relationships among all of the body systems and their regulation by hormones and other bioregulators, but also a sense of their development through evolutionary time as well as the roles of hormones at different stages of an animal's life cycle. Includes new full color format includes over 450 full color, completely redrawn image Features a companion web site hosting all images from the book as PPT slides and .jpeg files Presents completedly updated and revitalized content with new chapters, such as Endocrine Disrupters and Behavioral Endocrinology Offers new clinical correlation vignettes throughout

Research Review

Author :
Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Research Review by :

Download or read book Research Review written by and published by . This book was released on 1969 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of Nonlinear Dynamics To Developmental Process Modeling

Author : Karl M. Newell
Publisher : Psychology Press
ISBN 13 : 1317779126
Total Pages : 330 pages
Book Rating : 4.3/5 (177 download)

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Book Synopsis Applications of Nonlinear Dynamics To Developmental Process Modeling by : Karl M. Newell

Download or read book Applications of Nonlinear Dynamics To Developmental Process Modeling written by Karl M. Newell and published by Psychology Press. This book was released on 2014-03-05 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been an increasing interest in the application of dynamical systems to the study of development over the last decade. The explosion of the dynamical systems framework in the physical and biological sciences has opened the door to a new Zeitgeist for studying development. This appeal to dynamical systems by developmentalists is natural given the intuitive links between the established fundamental problems of development and the conceptual and operational scope of nonlinear dynamical systems. This promise of a new approach and framework within which to study development has led to some progress in recent years but also a growing appreciation of the difficulty of both fully examining the new metaphor and realizing its potential. Divided into 4 parts, this book is a result of a recent conference on dynamical systems and development held at Pennsylvania State University. The first 3 parts focus on the content domains of development that have given most theoretical and empirical attention to the potential applications of dynamical systems--physical growth and movement, cognition, and communication. These parts show that a range of nonlinear models have been applied to a host of developmental phenomena. Part 4 highlights two particular methodological issues that hold important implications for the modeling of developmental phenomena with dynamical systems techniques.

Nonlinear Dynamic Modeling of Physiological Systems

Author : Professor Vasilis Z. Marmarelis
Publisher : John Wiley & Sons
ISBN 13 : 9780471469605
Total Pages : 564 pages
Book Rating : 4.4/5 (696 download)

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Book Synopsis Nonlinear Dynamic Modeling of Physiological Systems by : Professor Vasilis Z. Marmarelis

Download or read book Nonlinear Dynamic Modeling of Physiological Systems written by Professor Vasilis Z. Marmarelis and published by John Wiley & Sons. This book was released on 2004-09-03 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Control Theory in Biomedical Engineering

Author : Olfa Boubaker
Publisher : Academic Press
ISBN 13 : 0128226218
Total Pages : 396 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Control Theory in Biomedical Engineering by : Olfa Boubaker

Download or read book Control Theory in Biomedical Engineering written by Olfa Boubaker and published by Academic Press. This book was released on 2020-06-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices). Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation

Research Review

Author : United States. Air Force. Office of Aerospace Research
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Research Review by : United States. Air Force. Office of Aerospace Research

Download or read book Research Review written by United States. Air Force. Office of Aerospace Research and published by . This book was released on 1969 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

OAR Research Review

Author : United States. Air Force. Office of Aerospace Research
Publisher :
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis OAR Research Review by : United States. Air Force. Office of Aerospace Research

Download or read book OAR Research Review written by United States. Air Force. Office of Aerospace Research and published by . This book was released on 1968 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Approaching Complex Diseases

Author : Mariano Bizzarri
Publisher : Springer Nature
ISBN 13 : 3030328570
Total Pages : 493 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Approaching Complex Diseases by : Mariano Bizzarri

Download or read book Approaching Complex Diseases written by Mariano Bizzarri and published by Springer Nature. This book was released on 2020-04-17 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.

Practical Numerical Algorithms for Chaotic Systems

Author : Thomas S. Parker
Publisher : Springer Science & Business Media
ISBN 13 : 1461234867
Total Pages : 354 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Practical Numerical Algorithms for Chaotic Systems by : Thomas S. Parker

Download or read book Practical Numerical Algorithms for Chaotic Systems written by Thomas S. Parker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the basic tenets of science is that deterministic systems are completely predictable-given the initial condition and the equations describing a system, the behavior of the system can be predicted 1 for all time. The discovery of chaotic systems has eliminated this viewpoint. Simply put, a chaotic system is a deterministic system that exhibits random behavior. Though identified as a robust phenomenon only twenty years ago, chaos has almost certainly been encountered by scientists and engi neers many times during the last century only to be dismissed as physical noise. Chaos is such a wide-spread phenomenon that it has now been reported in virtually every scientific discipline: astronomy, biology, biophysics, chemistry, engineering, geology, mathematics, medicine, meteorology, plasmas, physics, and even the social sci ences. It is no coincidence that during the same two decades in which chaos has grown into an independent field of research, computers have permeated society. It is, in fact, the wide availability of inex pensive computing power that has spurred much of the research in chaotic dynamics. The reason is simple: the computer can calculate a solution of a nonlinear system. This is no small feat. Unlike lin ear systems, where closed-form solutions can be written in terms of the system's eigenvalues and eigenvectors, few nonlinear systems and virtually no chaotic systems possess closed-form solutions.

Bone and Mineral Research

Author : Johannes N. M. Heersche
Publisher :
ISBN 13 : 1483290239
Total Pages : 385 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Bone and Mineral Research by : Johannes N. M. Heersche

Download or read book Bone and Mineral Research written by Johannes N. M. Heersche and published by . This book was released on 1990 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and Mineral Research.

The Quest for Fitness

Author : Mark Michaels
Publisher : iUniverse
ISBN 13 : 0595181333
Total Pages : 242 pages
Book Rating : 4.5/5 (951 download)

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Book Synopsis The Quest for Fitness by : Mark Michaels

Download or read book The Quest for Fitness written by Mark Michaels and published by iUniverse. This book was released on 2000-12 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Quest for Fitness: A rational exploration into the new science of organizations follows the tradition of Frederick Taylor and W. Edwards Deming by rationally applying scientific principles and processes to understanding the nature of organization. The book recognizes that the environment has changed drastically since Taylor applied Newtonian principles to describe the industrial organization. The synthesis forces the reader to change his/her view from considering how an organization can be created to take control of its environment to how one can be created to survive over time in a changing environment. The Quest for Fitness leaves the reader with a vision of organizations as complex adaptive organisms striving to stay fit on an ever-changing landscape. There is an ongoing search to optimize one’s position in an uncharted wilderness. Survival is not dependent upon the strongest but upon the ability to adapt as the landscape changes. The leaders of such organizations are no longer commanders, but explorers, who create network infrastructures enabling information to be received, integrated, and shared throughout the organization so that individual parts can best respond to immediate conditions, without the total system flying apart.

Stability and Oscillations of Nonlinear Pulse-Modulated Systems

Author : Arkadii Kh. Gelig
Publisher : Springer Science & Business Media
ISBN 13 : 1461217601
Total Pages : 367 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Stability and Oscillations of Nonlinear Pulse-Modulated Systems by : Arkadii Kh. Gelig

Download or read book Stability and Oscillations of Nonlinear Pulse-Modulated Systems written by Arkadii Kh. Gelig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two main fields of application of pulse-modulated sys tems, communications and control. Communication is not a subject of our concern in this book. Controlling by a pulse-modulated feed attracted our efforts. The peculiarity of this book is that all back the sampled-data systems are considered in continuous time, so no discrete time schemes are presented. And finally, we pay a little at tention to pulse-amplitude modulation which was treated in a vast number of publications. The primary fields of our interest are pulse width, pulse-frequency, and pulse-phase modulated control systems. The study of such systems meets with substantial difficulties. An engineer, who embarks on theoretical investigations of a pulse-mo dulated control, is often embarrassed by the sophisticated mathe matical tools he needs to know. When a mathematician, who looks for practical applications of his mathematical machinery, meets with these systems, he faces a lot of of complicated technical schemes and terms. Probably this is the reason why publications on pulse modu lation are seldom in scientific journals. As for books on this subject (save on amplitude modulation), the significant part of them is in Russian and hardly available for a non-Russian reader.

Cyclic Nucleotide Signaling

Author : XiaoDong Cheng
Publisher : CRC Press
ISBN 13 : 9780367658809
Total Pages : 288 pages
Book Rating : 4.6/5 (588 download)

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Book Synopsis Cyclic Nucleotide Signaling by : XiaoDong Cheng

Download or read book Cyclic Nucleotide Signaling written by XiaoDong Cheng and published by CRC Press. This book was released on 2021-03-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly informative, as will scientists already actively researching nucleotide signaling.

Endocannabinoids

Author : Emmanuel S Onaivi
Publisher : CRC Press
ISBN 13 : 9781420023640
Total Pages : 592 pages
Book Rating : 4.0/5 (236 download)

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Book Synopsis Endocannabinoids by : Emmanuel S Onaivi

Download or read book Endocannabinoids written by Emmanuel S Onaivi and published by CRC Press. This book was released on 2005-11-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.