Rna Tumor Viruses Oncogenes Human Cancer And Aids On The Frontiers Of Understanding

Download Rna Tumor Viruses Oncogenes Human Cancer And Aids On The Frontiers Of Understanding full books in PDF, epub, and Kindle. Read online Rna Tumor Viruses Oncogenes Human Cancer And Aids On The Frontiers Of Understanding ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding

Author : Philip Furmanski
Publisher : Springer Science & Business Media
ISBN 13 : 1461325838
Total Pages : 430 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding by : Philip Furmanski

Download or read book RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding written by Philip Furmanski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic significance, their role in cancer was proposed and hotly debated. The critical early discoveries, even those made as recently as 25 years ago, were met with rejection; not skepticism or cautious restraint, but outright rejection. During the 60's, there was a gradual acceptance of the association between viruses and cancer, the result of landmark studies in experimental systems, and this led to a frenzy of activity in the field. There followed another period of doubt and uncertainty, due to the difficulty in attempting to apply directly, and in retrospect inappropriately, the tenets of infectious disease to human cancers, only to have the field resurrected, revitalized and redirected by the explosion of progress in molecular biology and genetics.

Oncogenes, Aneuploidy, and AIDS

Author : Harvey Bialy
Publisher : North Atlantic Books
ISBN 13 : 9781556435317
Total Pages : 332 pages
Book Rating : 4.4/5 (353 download)

DOWNLOAD NOW!

Book Synopsis Oncogenes, Aneuploidy, and AIDS by : Harvey Bialy

Download or read book Oncogenes, Aneuploidy, and AIDS written by Harvey Bialy and published by North Atlantic Books. This book was released on 2004 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to author Harvey Bialy, the work of molecular biologist Peter Duesberg has been grossly distorted by the media and scientific establishments. Until recently, the scientific community--and most notably, those from the National Institute for Health--have been unwilling to look at his provocative theories of different causes for cancer and HIV/AIDS. Inspired by UC Berkeley's rare creation of an archive for Duesberg's papers, this book explores Duesberg's early groundbreaking work with viruses and oncogenes, his contentious fights with other scientists, and the profound influence of his life's work.

Biology of Carcinogenesis

Author : M.J. Waring
Publisher : Springer Science & Business Media
ISBN 13 : 9400932138
Total Pages : 229 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Biology of Carcinogenesis by : M.J. Waring

Download or read book Biology of Carcinogenesis written by M.J. Waring and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is no shonage of books on cancer. Why publish another? Simply because the subject is important: possibly the most important challenge facing medicine today, and consequently the focus of one of the faslest-growing areas of fundamental biological research. The quest to understand and control cancer is so absorbing that from time 10 time we really need to pause for a moment and try to take stock of the situation. Given the sheer breadth of cancer-related research that is not an easy task. This book, together with its planned successors in the series Cancer Biology and Medicine. represents our attempt to draw back from the bench or the bedside for a moment and take a slightly longer look at what we are doing, what we are trying to do, and where we stand. It is impossible to be comprehensive or even representative of more than a fraction of relevant knowledge. but that is no excuse for not trying to see things in perspective. Accordingly we set out to persuade a number of our colleagues to join us in writing a book which might admit a little fresh air into the confined atmosphere within which we mostly work: a glimpse, perhaps. of fresh vistas.

Scientific Directory and Annual Bibliography

Author : National Institutes of Health (U.S.)
Publisher :
ISBN 13 :
Total Pages : 690 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Scientific Directory and Annual Bibliography by : National Institutes of Health (U.S.)

Download or read book Scientific Directory and Annual Bibliography written by National Institutes of Health (U.S.) and published by . This book was released on 1986 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Science as Practice and Culture

Author : Andrew Pickering
Publisher : University of Chicago Press
ISBN 13 : 0226668207
Total Pages : 484 pages
Book Rating : 4.2/5 (266 download)

DOWNLOAD NOW!

Book Synopsis Science as Practice and Culture by : Andrew Pickering

Download or read book Science as Practice and Culture written by Andrew Pickering and published by University of Chicago Press. This book was released on 2010-11-15 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science as Practice and Culture explores one of the newest and most controversial developments within the rapidly changing field of science studies: the move toward studying scientific practice—the work of doing science—and the associated move toward studying scientific culture, understood as the field of resources that practice operates in and on. Andrew Pickering has invited leading historians, philosophers, sociologists, and anthropologists of science to prepare original essays for this volume. The essays range over the physical and biological sciences and mathematics, and are divided into two parts. In part I, the contributors map out a coherent set of perspectives on scientific practice and culture, and relate their analyses to central topics in the philosophy of science such as realism, relativism, and incommensurability. The essays in part II seek to delineate the study of science as practice in arguments across its borders with the sociology of scientific knowledge, social epistemology, and reflexive ethnography.

Ecologies of Knowledge

Author : Susan Leigh Star
Publisher : State University of New York Press
ISBN 13 : 1438420978
Total Pages : 438 pages
Book Rating : 4.4/5 (384 download)

DOWNLOAD NOW!

Book Synopsis Ecologies of Knowledge by : Susan Leigh Star

Download or read book Ecologies of Knowledge written by Susan Leigh Star and published by State University of New York Press. This book was released on 1995-07-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecologies of Knowledge provides a comprehensive overview of issues relating to work, politics, and the latest perspectives on the role of materials, feminism, "nonhumans," and work practices as shaping scientific and technical knowledge. In addition to theoretical contributions, the authors cover biotechnology, computing, representations and space, aerospace engineering, and a variety of ethical perspectives and controversies in these domains.

Retrovirus Biology and Human Disease

Author : Robert C. Gallo
Publisher : CRC Press
ISBN 13 : 1040277888
Total Pages : 442 pages
Book Rating : 4.0/5 (42 download)

DOWNLOAD NOW!

Book Synopsis Retrovirus Biology and Human Disease by : Robert C. Gallo

Download or read book Retrovirus Biology and Human Disease written by Robert C. Gallo and published by CRC Press. This book was released on 2024-11-01 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book captures some of the essential developments, both historical and current, relating to the human retroviruses and the diseases they cause. It describes detailed molecular biology and epidemiology of human T-leukemia virus type 1 (HTLV-1).

Grounded Theory in Practice

Author : Anselm L. Strauss
Publisher : SAGE
ISBN 13 : 9780761907480
Total Pages : 296 pages
Book Rating : 4.9/5 (74 download)

DOWNLOAD NOW!

Book Synopsis Grounded Theory in Practice by : Anselm L. Strauss

Download or read book Grounded Theory in Practice written by Anselm L. Strauss and published by SAGE. This book was released on 1997-03-11 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Grounded Theory in Practice presents a series of readings that emphasises different aspects of grounded theory methodology and methods. The selections are written by former students of the late Anselm Strauss.

Application of Monoclonal Antibodies in Tumor Pathology

Author : Dirk J. Ruiter
Publisher : Springer Science & Business Media
ISBN 13 : 9400932995
Total Pages : 387 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Application of Monoclonal Antibodies in Tumor Pathology by : Dirk J. Ruiter

Download or read book Application of Monoclonal Antibodies in Tumor Pathology written by Dirk J. Ruiter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of monoclonal antibodies to human tumor associated antigens has greatly facilitated the application of immunohistochemical techniques to analyze surgically removed tissues. During the last few years this approach has been utilized by a progressively increasing number of investigators to analyze malignant cells. Although monoclonal antibodies to tumor associated antigens have not become yet routine reagents in immunopathology, they have provided new information which could not be obtained with conventional antisera or histochemical procedures. The following are representative examples. TUmor associated antigens have been identified which display a restricted distribution in normal tissues and therefore may represent useful markers for radio imaging and appropriate targets for immunotherapy. In spite of undetec table differences with conventional histopathological approaches hetero geneity has been found in the antigenic profile of tumor cells within a lesion, in autologous lesions removed from different anatomic sites from a given patient and in lesions removed from different patients. Phenotypes of tumor cells have been identified which correlate with the biology of tumor cells and with the clinical course of the disease. From a practical view point the use of monoclonal antibodies in immunopathology has enhanced interactions between pathologists and immunologists, as exemplified by the present book. Such interactions have contributed to the application of basic research to clinical problems. The chapter of this book discuss investigations performed with monoclonal antibodies to antigens expressed by various types of normal and malignant human cells.

Crafting Science

Author : Joan H. Fujimura
Publisher : Harvard University Press
ISBN 13 : 9780674175532
Total Pages : 344 pages
Book Rating : 4.1/5 (755 download)

DOWNLOAD NOW!

Book Synopsis Crafting Science by : Joan H. Fujimura

Download or read book Crafting Science written by Joan H. Fujimura and published by Harvard University Press. This book was released on 1996 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the late 1970s and 1980s, "cancer" underwent a remarkable transformation. In one short decade, what had long been a set of heterogeneous diseases marked by uncontrolled cell growth became a disease of our genes. How this happened and what it means is the story Joan Fujimura tells in a rare inside look at the way science works and knowledge is created. A dramatic study of a new species of scientific revolution, this book combines a detailed ethnography of scientific thought, an in-depth account of science practiced and produced, a history of one branch of science as it entered the limelight, and a view of the impact of new genetic technologies on science and society. The scientific enterprise that Fujimura unfolds for us is proto-oncogene cancer research--the study of those segments of DNA now thought to make normal cells cancerous. Within this framework, she describes the processes of knowledge construction as a social enterprise, an endless series of negotiations in which theories, material technologies, and practices are co-constructed, incorporated, and refashioned. Along the way, Fujimura addresses long-standing questions in the history and philosophy of science, culture theory, and sociology of science: How do scientists create "good" problems, experiments, and solutions? What are the cultural, institutional, and material technologies that have to be in place for new truths and new practices to succeed? Portraying the development of knowledge as a multidimensional process conducted through multiple cultures, institutions, actors, objects, and practices, this book disrupts divisions among sociology, history, anthropology, and the philosophy of science, technology, and medicine.

Fundamental Problems in Breast Cancer

Author : Alexander H.G. Paterson
Publisher : Springer Science & Business Media
ISBN 13 : 1461320496
Total Pages : 392 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis Fundamental Problems in Breast Cancer by : Alexander H.G. Paterson

Download or read book Fundamental Problems in Breast Cancer written by Alexander H.G. Paterson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters in this book are those presented at the Second International Symposium on Fundamental Problems in Breast Cancer held at Banff, Alberta, April 26-29, 1986. This is, therefore, the second volume in the series of symposia held in the Canadian Rockies. The aim of these symposia is to provide a supportive atmosphere for the development of new concepts as well as for the presentation of high quality scientific data. This is reflected in the chapters presented here. Many of the chapters put forward new hypotheses which will be tested in the clinic or laboratory in the next few years. In choosing the subjects for discourse, we preferred to tackle areas where controversy existed, and in this book we have grouped the chapters around discussion themes. The relative merits of mammography and physical examination in the detection of small lesions within the breast and the natural history of these lesions were important topics at the symposium, and the results of early detection studies will have a major effect on health care costs. We have devoted a large section of this book to this subject. The mechanism of growth and response of endocrine sensitive tumors and current concepts of the statistics and cost-benefit assessment of adjuvant chemotherapy trials comprise two other sections of the book where original and stimulating ideas were presented.

Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

Author : Marino Nicolini
Publisher : Springer Science & Business Media
ISBN 13 : 1461317177
Total Pages : 813 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy by : Marino Nicolini

Download or read book Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy written by Marino Nicolini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 813 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fifth International Symposium, held in Abano Terme (Padova), italy, June 29-July 2, 1987

Pointers to Cancer Prognosis

Author : B.A. Stoll
Publisher : Springer Science & Business Media
ISBN 13 : 940093291X
Total Pages : 377 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Pointers to Cancer Prognosis by : B.A. Stoll

Download or read book Pointers to Cancer Prognosis written by B.A. Stoll and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last 30 years have seen little improvement in the age-adjusted mortality rates for most common types of cancer, and until we develop more effective and less damaging treatment modalities for these tumours, selection of each patient's treatment must depend on prognostic pointers. These lead to a calculated trade off between our estimate of likely benefit to the patient, as against cost in terms of quality of life. But changes have occurred recently in our understanding of the traditional prognostic pointers used for selecting such individualised treatment. First, it is increasingly recognised that the stage at which a tumour presents is more related to the chromo logical age of the tumour (how far it has progressed before diagnosis) than to its biological characteristics. While advanced chronological age of the tumour may predict a greater likelihood of early death, only biological criteria can predict the tumour growth rate, the likelihood of prolonged survival, the likely course of the disease after the first recurrence or the likehood of response to systemic therapy. Second, there is increasing use of failure analysis in relating the clinical and biological characteristics of tumours to their response to standard treatments. In the past, the relationship was interpreted mainly in terms of survival rate, but the site and timing of first recurrence and the pattern and timing of subsequent spread provide a better assessment of the control possible from local or systemic therapy.

Diagnosis and Management of Malignant Solid Tumors in Infants and Children

Author : Daniel M. Green
Publisher : Springer Science & Business Media
ISBN 13 : 1461326230
Total Pages : 531 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis Diagnosis and Management of Malignant Solid Tumors in Infants and Children by : Daniel M. Green

Download or read book Diagnosis and Management of Malignant Solid Tumors in Infants and Children written by Daniel M. Green and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pediatric oncology encompasses four groups of malignancies - acute leukemias, brain tumors, lymphomas and solid tumors. 1'he history, diagnosis and management of children with acute leukemias and lymphomas has been thoroughly examined in several excellent textbooks of pediatric hematology and oncology. Bl"ain tumors have historically been managed by neurosurgeons and radiation therapists. 1'he role of the pediatric oncologist in the management of these patients is evolving. This book was written to provide a thorough historical evaluation of the most frequent solid tumors of children. A detailed examination of the natural history of these tumors is essential to the design and evaluation of therapeutic trials. The highly lethal nature of many of these tumors, the occurrence of some of them at several different primary sites and the rarity of these tumors have made systematic study of them difficult. Conclusions regarding the efficacy of a particular modification of the therapeutic strategy can be strongly influenced by the assumed natural history of the tumor. I have tried to develop as accurateJy as the literature would allow a picture of the natural history of the common malignant solid tumors, knowing that the image would be imperfect. I adopted a convention which was employed in all graphs constructeil from case reports summarized from the literature.

Organ Directed Toxicities of Anticancer Drugs

Author : Miles P. Hacker
Publisher : Springer Science & Business Media
ISBN 13 : 1461320232
Total Pages : 259 pages
Book Rating : 4.4/5 (613 download)

DOWNLOAD NOW!

Book Synopsis Organ Directed Toxicities of Anticancer Drugs by : Miles P. Hacker

Download or read book Organ Directed Toxicities of Anticancer Drugs written by Miles P. Hacker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: The addition of chemotherapy as an effective means to treat cancer has had a major impact on selected human malignancies. Due to a general inability to dif ferentiate between normal and neoplastic cells, little selectivity exists in currently used oncolytic drugs. Consequently, significant toxicity to the patient is expected when systemic cancer chemotherapy is chosen as an appropriate therapeutic in tervention. Much of this toxicity, such as damage to the bone marrow, gastroin testinal tract, or hair follicles, is predictable based upon the fact that anticancer drugs kill actively dividing cells. These types of toxicities, while serious, are usually manageable and reversible and are, therefore, not often considered to be dose limiting. Unfortunately, several of the most important anticancer drugs also damage tissues in which the growth fraction is relatively small. Such toxicities can not be predicted based on the chemical structure of the drugs, are often not detected in preclinical studies, and are encountered frequently for the first time in clinical studies. Further, unlike most of the proliferative-dependent toxicities, the unpre dicted toxicities are usually irreversible or only partially reversible upon cessation of drug administration. Because of this, the unpredicted toxicities are referred to as dose limiting. They represent a significant barrier to the ultimate efficacy of several of our most important anticancer drugs.

Recent Concepts in Sarcoma Treatment

Author : J.R. Ryan
Publisher : Springer Science & Business Media
ISBN 13 : 940092691X
Total Pages : 348 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Recent Concepts in Sarcoma Treatment by : J.R. Ryan

Download or read book Recent Concepts in Sarcoma Treatment written by J.R. Ryan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been significant advances in the treatment of sarcomas in the past several years. Further, different clini cal treatment programs are being advocated in different areas including surgery alone, surgery with preoperative or post operative chemotherapy, surgery with different radiotherapy modalities, with each investigator espousing his own treat ment program. On the other side, there is the question of whether these treatment programs are offering better results or whether the natural history of sarcomas has changed. The International Symposium on Sarcomas was held at Innisbrook Resort, Tarpon Springs, Florida, October 8-10, 1987. This was the first international symposium to date involving all of the disciplines treating sarcomas including pathologists, orthopaedic surgeons, general surgeons, medical oncologists, pediatric oncologists, and radiation oncol ogists. The Symposium brought together a number of special ists working in the clinical field of sarcomas for a presen tation of their specific treatment programs and their results. The presentations were followed by panel discussions to stimulate educational debate as to the different forms of treatment for sarcomas and to formulate some conformity in control of disease, control of spread, and ultimate function for the patient. James R. Ryan, M.D.

Brain Oncology Biology, diagnosis and therapy

Author : M. Chatel
Publisher : Springer Science & Business Media
ISBN 13 : 9400933479
Total Pages : 428 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Brain Oncology Biology, diagnosis and therapy by : M. Chatel

Download or read book Brain Oncology Biology, diagnosis and therapy written by M. Chatel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Meeting on Brain Oncology in Rennes was organised in honor of Jean Pecker, to pay tribute to his contribution to the development of neurological sciences and to take stock of the current state of knowledge on brain tumors, a domain in which the role of neurosurgery has been and will continue to be primordial. During the two-day conference, the major themes of brain oncology studies, both fundamental and clinical, were examined: oncogenesis, tumoral markers and immunology, metabolic and diagnosis imaging, prognostic factors and therapeutic strategies. The large number and high quality of participations resulted in a genuinely synthetic view of current advances in research, of which this book presents the essentials. We have attempted both to preserve the richness of scientific exchanges which occurred and to publish a great many oral and poster communications. The book respects the organization of conference sessions, and thus reflects the importance accorded to glial tumor studies. This may seem disproportionate given their frequency of occurrence in proportion to total numbers of intracranial tumor processes, but their gravity and quasi-total resistance to current therapeutic methods are ample justification. Moreover, this is the domain in which hopes of progress are beginning to appear, and it is becoming possible to envisage treatment based on recently established fundamental knowledge.