Rna The Epicenter Of Genetic Information

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RNA, the Epicenter of Genetic Information

Author : John Mattick
Publisher : CRC Press
ISBN 13 : 1000623114
Total Pages : 879 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis RNA, the Epicenter of Genetic Information by : John Mattick

Download or read book RNA, the Epicenter of Genetic Information written by John Mattick and published by CRC Press. This book was released on 2022-09-20 with total page 879 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

RNA - a Genetic Messenger

Author : Edited by T. M. Jefferson
Publisher :
ISBN 13 : 9781533541840
Total Pages : 506 pages
Book Rating : 4.5/5 (418 download)

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Book Synopsis RNA - a Genetic Messenger by : Edited by T. M. Jefferson

Download or read book RNA - a Genetic Messenger written by Edited by T. M. Jefferson and published by . This book was released on 2016-05-30 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribonucleic acid (RNA) is a polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes. RNA and DNA are nucleic acids, and, along with proteins and carbohydrates, constitute the three major macromolecules essential for all known forms of life. Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA it is more often found in nature as a single-strand folded onto itself, rather than a paired double-strand. Cellular organisms use messenger RNA (mRNA) to convey genetic information (using the letters G, U, A, and C to denote the nitrogenous bases guanine, uracil, adenine, and cytosine) that directs synthesis of specific proteins. Many viruses encode their genetic information using an RNA genome.Some RNA molecules play an active role within cells by catalyzing biological reactions, controlling gene expression, or sensing and communicating responses to cellular signals. One of these active processes is protein synthesis, a universal function wherein mRNA molecules direct the assembly of proteins on ribosomes. This process uses transfer RNA (tRNA) molecules to deliver amino acids to the ribosome, where ribosomal RNA (rRNA) then links amino acids together to form proteins.This book gives a comprehensive overview of the various functions of RNA.

DNA and RNA

Author : Jenny Chen
Publisher : Cavendish Square Publishing, LLC
ISBN 13 : 1502619555
Total Pages : 130 pages
Book Rating : 4.5/5 (26 download)

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Book Synopsis DNA and RNA by : Jenny Chen

Download or read book DNA and RNA written by Jenny Chen and published by Cavendish Square Publishing, LLC. This book was released on 2016-07-15 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA and RNA explores Friedrich Miescher's major scientific discovery in 1944 when he isolated DNA for the first time, forever changing our understanding of the building blocks of the human body. The book looks at Miescher's path to isolating DNA and the ways that his work influenced James Watson and Francis Crick, who discovered the double helix in 1957. DNA and RNA describes the many ways that these discoveries are relevant to our lives, as well as the numerous ethical implications of the discoveries.

RNA

Author : Henrik Nielsen
Publisher : Humana Press
ISBN 13 : 9781493956432
Total Pages : 329 pages
Book Rating : 4.9/5 (564 download)

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Book Synopsis RNA by : Henrik Nielsen

Download or read book RNA written by Henrik Nielsen and published by Humana Press. This book was released on 2017-04-30 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent insight into the transcripts generated from the mammalian genome (i.e. the transcriptome) has revealed that transcription is a far more complex phenomenon than previously thought. In RNA: Methods and Protocols, expert researchers provide the procedures and methods used to describe the structure of messenger RNAs and non-coding RNAs that are transcribed by RNA polymerase II as the immediate gene products in mammalian cells. Focused on the structure of the RNA products of “gene X” and the mapping of proteins associated with these RNAs, the volume presents appropriate information for non-specialists in RNA biology. Written in the highly successful Methods in Molecular BiologyTM series format, many chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, RNA: Methods and Protocols views the transcriptional landscape with an appreciation for the role that proteins play in the processing and interpretation of genetic information in an attempt to further our crucial knowledge of the many products and sophisticated regulatory networks that result from it.

Inside DNA and RNA

Author : Howard Phillips
Publisher : 'The Rosen Publishing Group, Inc'
ISBN 13 : 1499470398
Total Pages : 82 pages
Book Rating : 4.4/5 (994 download)

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Book Synopsis Inside DNA and RNA by : Howard Phillips

Download or read book Inside DNA and RNA written by Howard Phillips and published by 'The Rosen Publishing Group, Inc'. This book was released on 2021-12-15 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells are the basic units of life, but within them are even smaller structures that act as the machinery that keeps us alive. This include the key molecules in cellular biology, deoxyribonucleic acid and ribonucleic acid—better known as DNA and RNA. These teammates have essential jobs and they work together to make life possible. DNA stores and transfers genetic information, while RNA codes for amino acids and acts as a messenger in the making of proteins. This enlightening book erases much of the mystique surrounding the science of genetics, thanks to thorough explanations of DNA and RNA at work within the body. Numerous diagrams help make this potentially difficult topic more accessible.

DNA, RNA, and the Inheritance of Traits

Author : Don Rauf
Publisher : Enslow Publishing, LLC
ISBN 13 : 0766099431
Total Pages : 82 pages
Book Rating : 4.7/5 (66 download)

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Book Synopsis DNA, RNA, and the Inheritance of Traits by : Don Rauf

Download or read book DNA, RNA, and the Inheritance of Traits written by Don Rauf and published by Enslow Publishing, LLC. This book was released on 2018-07-15 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do people have certain traits and talents? We are all who we are because cells in our bodies grow and respond according to instructions from DNA molecules. RNA carries the DNA details from the cell nucleus to other parts of the cell. Engaging language and detailed, colorful images and diagrams simplify complicated scientific principles into pieces of information students can comprehend more easily. They will gain a deeper understanding of how DNA and RNA work together to make all the individual humans, animals, and plants on our planet.

Molecular Biology of RNA

Author : David Elliott
Publisher : Oxford University Press
ISBN 13 : 0199671397
Total Pages : 437 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Molecular Biology of RNA by : David Elliott

Download or read book Molecular Biology of RNA written by David Elliott and published by Oxford University Press. This book was released on 2016 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and in catalysis.This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. For the secondedition of Molecular Biology of RNA more introductory material has been incorporated at the beginning of the text, while new material has been included throughout - particularly in relation to RNA bindingdomains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

RNA Genetics

Author : Esteban Domingo
Publisher : CRC Press
ISBN 13 : 1351093347
Total Pages : 266 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis RNA Genetics by : Esteban Domingo

Download or read book RNA Genetics written by Esteban Domingo and published by CRC Press. This book was released on 2018-01-18 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 2018. Routledge is an imprint of Taylor & Francis, an Informa company.

The origin of genetic information

Author : Manfred Eigen
Publisher :
ISBN 13 :
Total Pages : 17 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis The origin of genetic information by : Manfred Eigen

Download or read book The origin of genetic information written by Manfred Eigen and published by . This book was released on 1991 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RNA

Author : James E. Darnell
Publisher :
ISBN 13 : 9781936113194
Total Pages : 0 pages
Book Rating : 4.1/5 (131 download)

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Book Synopsis RNA by : James E. Darnell

Download or read book RNA written by James E. Darnell and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA molecules could function as catalysts. --

RNA Biology

Author : Gunter Meister
Publisher : Wiley-VCH
ISBN 13 : 9783527322787
Total Pages : 0 pages
Book Rating : 4.3/5 (227 download)

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Book Synopsis RNA Biology by : Gunter Meister

Download or read book RNA Biology written by Gunter Meister and published by Wiley-VCH. This book was released on 2011-05-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998. Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts, adopting instead a modern approach in both concept and scope. The text is divided into three parts, on mRNA, non-coding RNA, and RNomics, and the author addresses the traditional roles of RNA in the transmission and regulation of genetic information, as well as the recently discovered functions of small RNA species in pathogen defense, cell differentiation and higher-level genomic regulation. All set to become the standard for teaching molecular science to biologists and biochemists.

RNA Worlds: New Tools for Deep Exploration

Author : Thomas R. Cech
Publisher :
ISBN 13 : 9781621822240
Total Pages : 580 pages
Book Rating : 4.8/5 (222 download)

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Book Synopsis RNA Worlds: New Tools for Deep Exploration by : Thomas R. Cech

Download or read book RNA Worlds: New Tools for Deep Exploration written by Thomas R. Cech and published by . This book was released on 2018-12-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A Subject Collection from Cold Spring Harbor Perspectives in Biology."

Epigenetics in Biological Communication

Author : Guenther Witzany
Publisher : Springer Nature
ISBN 13 : 3031592867
Total Pages : 441 pages
Book Rating : 4.0/5 (315 download)

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Book Synopsis Epigenetics in Biological Communication by : Guenther Witzany

Download or read book Epigenetics in Biological Communication written by Guenther Witzany and published by Springer Nature. This book was released on with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Diagnostics of Cancer

Author : Pier Paolo Piccaluga
Publisher : BoD – Books on Demand
ISBN 13 : 1837694346
Total Pages : 286 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Molecular Diagnostics of Cancer by : Pier Paolo Piccaluga

Download or read book Molecular Diagnostics of Cancer written by Pier Paolo Piccaluga and published by BoD – Books on Demand. This book was released on 2024-04-10 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision medicine, also known as personalized medicine, is an innovative approach to medical treatment and diagnosis that takes into account individual variability in genes, environment, and lifestyle for each person. In the context of cancer, precision medicine aims to tailor medical care to the specific genetic and molecular characteristics of each patient's tumor. This allows for more targeted and effective treatments, minimizing side effects and improving outcomes. The first step in precision medicine, especially in oncology, is represented by an accurate diagnosis, including molecular and genetic data. A comprehensive assessment in molecular pathology includes conventional and more innovative techniques, including polymerase chain reaction (PCR)-based approaches, Sanger sequencing, and next-generation sequencing for genomic profiling. Precision medicine relies on the analysis of the patient's genomic information, including the DNA mutations present in their tumor. Genomic profiling helps identify specific genetic alterations that are driving the growth of cancer cells. This information is crucial for selecting targeted therapies that directly interfere with these specific molecular abnormalities. In addition, molecular diagnostics provide: • biomarker identification • tumor heterogeneity assessment In turn, this translates into direct treatment decision support. The information obtained through molecular tests guides oncologists in making more informed decisions about the most appropriate treatments for individual patients. This can include targeted therapies, immunotherapies, or other interventions based on the specific molecular profile of the tumor. Prognostication becomes treatment-specific (prediction) and predictive models can be developed by integrating genetic and molecular data with clinical information, to estimate the likelihood of treatment response, recurrence, and overall prognosis. Overall, molecular pathology has significantly advanced cancer diagnostics and treatment, leading to improved outcomes and a shift toward more personalized and effective care. The integration of molecular diagnostics and genomic information has transformed how cancer is understood and managed, offering new hope for patients and providing oncologists with powerful tools to combat the complexity of the disease.

The Fundamentals of Biophysics

Author :
Publisher : Cybellium
ISBN 13 : 1836790643
Total Pages : 224 pages
Book Rating : 4.8/5 (367 download)

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Book Synopsis The Fundamentals of Biophysics by :

Download or read book The Fundamentals of Biophysics written by and published by Cybellium. This book was released on with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

Introduction to Genetics: A Molecular Approach

Author : T A Brown
Publisher : Garland Science
ISBN 13 : 1136665358
Total Pages : 554 pages
Book Rating : 4.1/5 (366 download)

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Book Synopsis Introduction to Genetics: A Molecular Approach by : T A Brown

Download or read book Introduction to Genetics: A Molecular Approach written by T A Brown and published by Garland Science. This book was released on 2012-03-22 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics.

RNA Structure and Function

Author : Jan Barciszewski
Publisher : Springer Nature
ISBN 13 : 3031363906
Total Pages : 662 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis RNA Structure and Function by : Jan Barciszewski

Download or read book RNA Structure and Function written by Jan Barciszewski and published by Springer Nature. This book was released on 2023-12-05 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved. RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine. In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases. This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry.