Research Methods In Neurochemistry

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Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577519
Total Pages : 422 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section I Ultrastructure and Fragmentation of Neural Tissue.- 1 Bulk Separation of Neuronal Cell Bodies and Glial Cells in the Absence of Added Digestive Enzymes.- I. Introduction.- II. Bulk Isolation Procedures Requiring No Added Digestive Enzyme(s).- A. The Procedure Developed in the Authors' Laboratory.- B. The Procedure of Nagata et al. (1971).- C. The Procedure of Iqbal and Tellez-Nagel (1972).- D. The Procedure of Jones et al. (1971).- III. General Procedural Comments.- IV. Cell Yield and Biochemical Characterization.- V. Applications in Cellular Neurochemistry.- A. Centrifugal Fractiona.

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577489
Total Pages : 376 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: On picking up this first volume of a new series of books the reader may ask the two questions: (a) why research methods? and (b) why in neurochem istry? The answers to these questions are easy - they more than justify the volumes to come and show the strong need for their existence. It is customary to think of methods as a necessary but unexciting means to an end - to relegate advances in methodology to a minor role in the creative, original portion of advances in science. This is not the case; the pace-setting function of methodology is well illustrated in most areas of neurobiology. To formulate our questions to Nature (which is the essence of experimental design), methodology is needed; to get answers to our ques tions we have to devise yet new methods. The chapters of the present volume fully illustrate how the development of a new method can cut a new path how it can open new fields, just as the microscope founded histology. Heter ogeneity of structures presents a formidable challenge for methodology in the nervous system, yet methods for separating the structures are essential if we ever want to decipher the enigma of functional contribution of the ele ments to the whole. The problem is not only physical separation-clearly methods are essential to study complex structures in situ.

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577608
Total Pages : 381 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Research methods in neurochemistry

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (761 download)

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Download or read book Research methods in neurochemistry written by and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461344581
Total Pages : 476 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the continued rapid expansion of neurochemical research, there has been no shortage of new developments in methodology for this third volume of Research Methods in Neurochemistry. As in previous volumes we have again tried to provide some balance in the subjects represented. The wisdom of this policy may be questioned since it can lead to delay in publica tion, but there are many approaches to the chemical study of the nervous system and a methods book needs to stand on its own as well as be part of a series. In one respect, however, the present volume departs from this policy, in that we have included two chapters on micromethods for analyzing amines and amino acids, both giving special emphasis to dansylation techniques. These chapters are complementary and we feel justified in publishing them in one volume in view of the importance of such micromethods for the study of neural systems. At the other end of the scale, particular attention may be drawn to the chapter by D. D. Gilboe and colleagues describing their remarkable procedures for studying metabolism in the isolated canine brain. We were fortunate also in persuading S. S. Oja to extend the general prin ciples of transport systems he described in Volume 2 to amino acids in brain slices. In addition, there are the usual chapters on components of neural tissues, which once again we have found convenient to divide into enzymes, macromolecules, and other constituents.

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer. This book was released on 1978-06 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth volume of Research Methods in Neurochemistry includes chapters on different aspects of topics touched on in previous volumes and develops a number of new themes as well. The bias, though not entirely intended, is directed toward studies of macromolecules, both at the meta bolic level in relation to protein synthesis and at the structural level in rela tion to specific proteins and lipids. The new departures concern subjects in Section I with marked applied bias: biochemical studies of nervous system tumors and of the cerebrospinal fluid, both of which we hope will be of value to clinical as well as basic scientists. Biogenic amines and the enzymes involved in their metabolism figure again in Section II, where the powerful tool of mass spectrometry receives further treatment in relation to the analysis of dansyl derivatives of trace amines in the brain. Once again we remain grateful to the individual authors, both for their contributions and patience, and to Plenum Press for their continued interest and cooperation. Thanks are also due to colleagues and friends for their comments and criticisms on the series as a whole; suggestions for future volumes will always be welcome and should be sent to one of the editors. Richard Rodnight, London Neville Marks, New York March 1978 ix Contents Section I PROPERTIES OF INTACT NEURAL TISSUES Chapter 1 Biochemical Study of Tumors of the Nervous System. . . . . . . . . . . . . . . . 3 Norman Allen I. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II. Human Brain Tumors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 A. Autopsy Specimens. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer Science & Business Media
ISBN 13 : 1461577578
Total Pages : 325 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fifth volume of Research Methods in Neurochemistry represents a milestone in that it marks almost a decade since the inception of the series. Over these ten years there has been an almost exponential growth in neuro chemistry accompanied by numerous technical developments. This is the justification for our series; inevitably we have only been able to cover a frac tion of the methodological innovations of the last decade, but we have tried as much as possible to create a balance between the different approaches and philosophies in the study of the chemical basis of brain function. Thus our original format of grouping chapters under various headings-for instance, studies in intact tissues as distinct from studies describing constituents and isolated enzymes-appears to be justified. Studies on whole animals or tissues retaining cellular organization are vital in providing insights into the neurochemical mechanism underlying functional processes; at the same time, the eventual understanding of function can only be attained on the basis of knowledge of the molecular architecture of the tissue. In the present volume, Oldendorfs chapter on the transport of radiolabeled metabolites across the blood-brain barrier illustrates one side of this equation, whereas Poduslo's chapter on the separation of oligo dendroglia! cells provides new information on the role of these cells in myelogenesis and the distinctive chemical composition of glia as compared to neurons.

Research Methods in Neurochemistry

Author : Neville Marks
Publisher :
ISBN 13 : 9781461577522
Total Pages : 436 pages
Book Rating : 4.5/5 (775 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by . This book was released on 2014-09-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methods in Neurochemistry, Vol 1

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Download or read book Research Methods in Neurochemistry, Vol 1 written by and published by . This book was released on 1972 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methods in Neurochemistry

Author : Neville Marks
Publisher : Springer
ISBN 13 : 9780306360015
Total Pages : 368 pages
Book Rating : 4.3/5 (6 download)

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Book Synopsis Research Methods in Neurochemistry by : Neville Marks

Download or read book Research Methods in Neurochemistry written by Neville Marks and published by Springer. This book was released on 1995-12-31 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: On picking up this first volume of a new series of books the reader may ask the two questions: (a) why research methods? and (b) why in neurochem istry? The answers to these questions are easy - they more than justify the volumes to come and show the strong need for their existence. It is customary to think of methods as a necessary but unexciting means to an end - to relegate advances in methodology to a minor role in the creative, original portion of advances in science. This is not the case; the pace-setting function of methodology is well illustrated in most areas of neurobiology. To formulate our questions to Nature (which is the essence of experimental design), methodology is needed; to get answers to our ques tions we have to devise yet new methods. The chapters of the present volume fully illustrate how the development of a new method can cut a new path how it can open new fields, just as the microscope founded histology. Heter ogeneity of structures presents a formidable challenge for methodology in the nervous system, yet methods for separating the structures are essential if we ever want to decipher the enigma of functional contribution of the ele ments to the whole. The problem is not only physical separation-clearly methods are essential to study complex structures in situ.

Guide to Research Techniques in Neuroscience

Author : Matt Carter
Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Research Methods in Neurochemistry, V.6

Author : Neville Marks
Publisher :
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.:/5 (117 download)

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Book Synopsis Research Methods in Neurochemistry, V.6 by : Neville Marks

Download or read book Research Methods in Neurochemistry, V.6 written by Neville Marks and published by . This book was released on 1985 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methods in Neurochemistry, Vol. 5

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Download or read book Research Methods in Neurochemistry, Vol. 5 written by and published by . This book was released on 1981 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

RESEARCH METHODS IN NEUROCHEMISTRY. 1972

Author : ED MARKS
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (143 download)

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Book Synopsis RESEARCH METHODS IN NEUROCHEMISTRY. 1972 by : ED MARKS

Download or read book RESEARCH METHODS IN NEUROCHEMISTRY. 1972 written by ED MARKS and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Basic Neurochemistry

Author : R. Wayne Albers
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1121 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Basic Neurochemistry by : R. Wayne Albers

Download or read book Basic Neurochemistry written by R. Wayne Albers and published by Academic Press. This book was released on 2011-11-02 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475

Principles of Neurochemistry

Author : Bijo Mathew
Publisher : Springer Nature
ISBN 13 : 9811551677
Total Pages : 198 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Principles of Neurochemistry by : Bijo Mathew

Download or read book Principles of Neurochemistry written by Bijo Mathew and published by Springer Nature. This book was released on 2020-09-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the book addresses topics that transcend the borders between disciplines, and presents a wealth of investigations into and discussions on critical questions relevant to the entire field of CNS drug research. It summarizes the available data on the fundamentals of neurotransmitters, treatment of and advanced care for neurodegenerative diseases; and outlines current and future research directions in this field. Combining both conventional and innovative approaches to the topic, the book offers a valuable guide for readers working in medicinal chemistry, the life sciences and allied fields.

Focus on Neurochemistry Research

Author : Robert M. Coleman
Publisher : Nova Publishers
ISBN 13 : 9781594544170
Total Pages : 270 pages
Book Rating : 4.5/5 (441 download)

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Book Synopsis Focus on Neurochemistry Research by : Robert M. Coleman

Download or read book Focus on Neurochemistry Research written by Robert M. Coleman and published by Nova Publishers. This book was released on 2005 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is an enormously dynamic organ. Even when we sleep connections are made, signals sent and messages delivered. One of the key ways that the brain operates is via chemical stimuli which permits different parts of the brain to communicate between themselves and with the rest of the body. Determining what these chemicals, proteins and molecules are is an important way to not only discover how the brain works, but provide novel targets that may be useful in the treatment of disease, for instance in dealing with memory loss in dementia. This new book brings together international research in a broad range of topics, including molecular and cellular neurochemistry, neuropharmacology and genetic aspects of CNS function, neuroimmunology, metabolism, as well as the neurochemistry of neurological and psychiatric disorders of the CNS.