Report on the Advancements of Pharmaceutical Chemistry and Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 222 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Report on the Advancements of Pharmaceutical Chemistry and Therapeutics by :

Download or read book Report on the Advancements of Pharmaceutical Chemistry and Therapeutics written by and published by . This book was released on 1903 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics, 1912, Vol. 25 (Classic Reprint)

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Publisher : Forgotten Books
ISBN 13 : 9780484444903
Total Pages : 518 pages
Book Rating : 4.4/5 (449 download)

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Book Synopsis E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics, 1912, Vol. 25 (Classic Reprint) by : E. Merck

Download or read book E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics, 1912, Vol. 25 (Classic Reprint) written by E. Merck and published by Forgotten Books. This book was released on 2017-12-22 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics, 1912, Vol. 25 As far back as 1870 I undertook to furnish my friends and customers with short reports on recent therapeutic preparations, as at that time the professional journals did not contain as detailed and complete accounts of recent discoveries in the field of pharmaco therapy as is now the case. These communications, which appeared at irregular intervals, developed in the course of years into the regular Annual Report. Its aim from the first was to collect the most important items from the entire international literature, all the information that was likely to prove of interest to physicians and pharmacists, and to present it in a perfectly, impartial manner, leaving the reader to examine the information and to decide upon its actual value. I have therefore scrupulously avoided expressing my own views upon the results obtained by others, provided these communications did not conceal some actual danger, to which it was absolutely necessary to draw attention. On account of this impartiality, combined with as comprehensive a report as possible, the Annual Report has been so highly appreciated that the number of copies printed has had to be increased from year to year. At the present time it is published in four languages (german, English, French and Russian), the total annual edition amounting to copies. This steady increase of the annual edition is evidence that the Annual Report supplies a real want. 'further, it bears elo quent testimony that the Annual Report has succeeded in satis tying its readers. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

Recent Advances in Medicinal Chemistry, Volume 1

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Publisher : Elsevier
ISBN 13 : 0128039620
Total Pages : 487 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Recent Advances in Medicinal Chemistry, Volume 1 by : Atta-ur Rahman

Download or read book Recent Advances in Medicinal Chemistry, Volume 1 written by Atta-ur Rahman and published by Elsevier. This book was released on 2015-06-16 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. Edited and written by leading experts in medicinal chemistry research Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health

E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics by :

Download or read book E. Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics written by and published by . This book was released on 1912 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Research on Medicinal Chemistry

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Publisher : Taylor & Francis
ISBN 13 : 135180023X
Total Pages : 460 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Handbook of Research on Medicinal Chemistry by : Debarshi Kar Mahapatra

Download or read book Handbook of Research on Medicinal Chemistry written by Debarshi Kar Mahapatra and published by Taylor & Francis. This book was released on 2017-11-20 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and nutraceuticals. The editors keep the drug molecule as the central component of the volume and aim to explain the associated features essential to exhibiting pharmacological activity. With a unique combination of chapters in biology, clinical aspects, biochemistry, synthetic chemistry, medicine and technology, the volume provides broad exposure to the essential aspect of pharmaceuticals. The volume many important aspects of medicinal chemistry, including techniques in drug discovery pharmacological aspects of natural products chemical mediators: druggable targets advances in medicinal chemistry The field of medicinal chemistry is growing at an unprecedented pace, and this volume takes an interdisciplinary approach, covering a range of new research and new practices in the field. The volume takes into account the latest therapeutic guidelines put forward by the World Health Organization and the U.S Food and Drug Administration.. Topics include: drug design drug discovery natural products and supplements and nutraceuticals pharmaceutical approaches to sexual dysfunction drug resistance parasites new natural compounds and identification of new targets stereochemistry aspects in medicinal chemistry common drug interactions in daily practices Handbook of Research on Medicinal Chemistry: Innovations and Methodologies will be a valuable addition to the bookshelves of pharmaceutical scientists and faculty as well as for industry professionals.

Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics by :

Download or read book Merck's Annual Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics written by and published by . This book was released on 1912 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics

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Publisher :
ISBN 13 :
Total Pages : 1154 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics by :

Download or read book Report of Recent Advances in Pharmaceutical Chemistry and Therapeutics written by and published by . This book was released on 1904 with total page 1154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

E. Merck, Darmstadt. Annual Report on the Year 1893[-1902]. [On the Advancements of Pharmaceutical Chemistry and Therapeutics.].

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (562 download)

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Book Synopsis E. Merck, Darmstadt. Annual Report on the Year 1893[-1902]. [On the Advancements of Pharmaceutical Chemistry and Therapeutics.]. by : Heinrich Emanuel MERCK

Download or read book E. Merck, Darmstadt. Annual Report on the Year 1893[-1902]. [On the Advancements of Pharmaceutical Chemistry and Therapeutics.]. written by Heinrich Emanuel MERCK and published by . This book was released on 1894 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Medicinal Chemistry Research

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Publisher :
ISBN 13 : 9781536163681
Total Pages : 366 pages
Book Rating : 4.1/5 (636 download)

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Book Synopsis Advances in Medicinal Chemistry Research by : Edeildo Ferreira Da Silva, Jr.

Download or read book Advances in Medicinal Chemistry Research written by Edeildo Ferreira Da Silva, Jr. and published by . This book was released on 2019-10-15 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting points for the design of drugs against obesity, multidrug-resistant bacteria, neglected tropical diseases, Alzheimer, and cancer. From the prediction of promising hits and identification of active compounds to the extraction of more complex molecules, this book explores a range of essential topics to support the development of novel, economical, and efficacious therapeutics for these diseases, which currently affect a billion people worldwide. Beginning with an overview of obesity, showing the current research landscape, the books shows the importance of natural and synthetic products as promising anti-obesity agents. Subsequently, the medicinal chemistry of modulation of bacterial resistance is presented, focusing on the MFS, RND, ABC, and MATE superfamilies. The book goes on to discuss such topics as antituberculosis, antileishmanial, and anti-hepatitis thiophene-containing compounds, under the medicinal chemistry point of view. Also, potent human glutaminyl cyclase inhibitors are deeply discussed and displayed as hopeful anti-Alzheimer's agents. The last three chapters are focused on the development of researches involving new anticancer agents, initializing with LBDD, SBDD, QSAR, and QM/MM methods applied to the identification of novel promising anticancer compounds. Moreover, IDO1 inhibitors are exhaustively explored and analyzed as a new promise for the immunotherapy of cancer. Finally, a great update on Eg5 kinesin inhibitors is provided, exploring different chemical classes of synthetic and natural compounds, including miscellanea as a new approach for Eg5 inhibition. Combining the expertise of researchers from around the world, this volume aims to support and encourage researches for the development of novel, safe, and active agents against lipase enzyme, bacteria, neglected tropical diseases, Alzheimer, and cancer. The clear narrative truly engages the reader, holding their attention right from the opening of a chapter, and maintaining interest and understanding as a chapter leads into more complex material. Advances in Medicinal Chemistry Research is a book that reviews ongoing developments and recent cutting-edge advances in medicinal chemistry of the most relevant diseases found nowadays, underlining how medicinal chemistry research continues to make significant contributions to the discovery and development of new therapeutic entities. Key Features â¢Chapters written by active specialists and leading experts deeply engaged in the research field of most deadly and limiting diseases for drug discovery. â¢Draws together cutting-edge research advances in medicinal chemistry focused at the obesity, multidrug-resistant microorganisms, Alzheimer, and cancer in a single volume. â¢Highlights the future potential of researches for the medicinal chemistry of most impactful diseases today. â¢Contents addressed to medicinal chemistry, biochemistry, biology, and pharmacy students, professors, and researchers.

Advances and Challenges in Pharmaceutical Technology

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Publisher : Academic Press
ISBN 13 : 0128203005
Total Pages : 572 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Advances and Challenges in Pharmaceutical Technology by : Amit Kumar Nayak

Download or read book Advances and Challenges in Pharmaceutical Technology written by Amit Kumar Nayak and published by Academic Press. This book was released on 2021-02-09 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology Includes contributions from global leaders and experts in academia, industry and regulatory agencies Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

The Role of NIH in Drug Development Innovation and Its Impact on Patient Access

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Publisher : National Academies Press
ISBN 13 : 0309498511
Total Pages : 103 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Role of NIH in Drug Development Innovation and Its Impact on Patient Access by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.

Improving and Accelerating Therapeutic Development for Nervous System Disorders

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Publisher : National Academies Press
ISBN 13 : 0309292492
Total Pages : 107 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine

Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Discoveries in Pharmacological Sciences

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Publisher : World Scientific
ISBN 13 : 9814355089
Total Pages : 793 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Discoveries in Pharmacological Sciences by : Popat N. Patil

Download or read book Discoveries in Pharmacological Sciences written by Popat N. Patil and published by World Scientific. This book was released on 2012 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1805 pure, active, therapeutic constituents were isolated and chemically characterized. Parallel to these developments, the science of human anatomy, physiology, biochemistry, genetics and pharmacology has advanced. New synthetic drugs were discovered. The chemistry of perfumes and sensory functions including memory were elucidated. The history of fascinating discoveries made by scientists of Nobel repute was documented. Better testing methods were developed. The causes of many diseases were better understood. Drug laws were instituted a century ago. The pharmaceutical industry flourished. The text provides a panoramic view of the understanding of when, where, who, how and why drugs were developed. Educational aspects of teaching pharmacological sciences are reviewed. The historical account will be invaluable to graduate students and creative scientists, who can prepare for the future.

E. Merck's Annual Report

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Publisher :
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis E. Merck's Annual Report by : Emanuel Merck

Download or read book E. Merck's Annual Report written by Emanuel Merck and published by . This book was released on 1904 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Medicinal Chemistry

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Publisher : Elsevier
ISBN 13 : 0080526373
Total Pages : 338 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Medicinal Chemistry by : B.E. Maryanoff

Download or read book Advances in Medicinal Chemistry written by B.E. Maryanoff and published by Elsevier. This book was released on 1999-04-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.

Pharmaceutical Formulation and Medicinal Chemistry

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Publisher :
ISBN 13 : 9781634840828
Total Pages : 0 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis Pharmaceutical Formulation and Medicinal Chemistry by : Bruce Moore

Download or read book Pharmaceutical Formulation and Medicinal Chemistry written by Bruce Moore and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews research on pharmaceutical formulation and medicinal chemistry. It begins with a summary of old and new discoveries on therapeutic applications of the A3 adenosine receptor in inflammation and cancer, and highlights the most important agonists and antagonists developed for the A3 adenosine receptor, explicitly those in clinical trials for the treatment of inflammation and/or cancer. The next chapter addresses and highlights the different inhibitions against metastases in vivo and molecular mechanisms of action in vitro of Biz compounds especially relating to the inhibitory efficacies against tumor metastasis and other important clinical utilisations including inhibitory pathways against angiogenesis, topoisomerase II, calmodulin, sialic acid, fibrinogen, drug combinations, medicinal chemistry, cell-movement and so on. Chapter three focuses on concepts of isosterism and bioisosterism in modern medicinal chemistry. The final chapter discusses the determination of L-Dopa in pharmaceutical formulations with a glassy carbon electrode (GCE) modified with cobalt phthalocyanine (CoPc) adsorbed on multi-walled carbon nanotubes (MWCN).

Original Papers

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Publisher :
ISBN 13 :
Total Pages : 1322 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Original Papers by : Henry Kraemer

Download or read book Original Papers written by Henry Kraemer and published by . This book was released on 1908 with total page 1322 pages. Available in PDF, EPUB and Kindle. Book excerpt: