Regulators of G Protein Signaling

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Publisher : Elsevier
ISBN 13 : 0080497276
Total Pages : 560 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Regulators of G Protein Signaling by :

Download or read book Regulators of G Protein Signaling written by and published by Elsevier. This book was released on 2004-11-16 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulators of G Protein Signaling, Part B continues the in-depth treatment of the topic and covers the RSG protein superfamily including RZ, R4, R7, R12, RhoGEF, and GRK, as well as other heterotrimeric G-protein signaling regulators. Table of Contents RZ Subfamily R4 Subfamily R7 Subfamily R12 Subfamily RhoGEF Subfamily GRK Subfamily Other RGS proteins Activators Inhibitors Other Modulators

Regulators of G Protein Signaling

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Author :
Publisher : Elsevier
ISBN 13 : 0080497268
Total Pages : 480 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Regulators of G Protein Signaling by :

Download or read book Regulators of G Protein Signaling written by and published by Elsevier. This book was released on 2004-11-25 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulators of G Protein Signaling, Part A is an in-depth treatment of G-Protein Signaling, and will cover general methods of analysis of RGS protein analysis, including Expression and post-translational modification, Assays of GAP activity and allosteric control, Electrophysiological methods and RGS-insensitive Ga subunits, Mouse models of RGS protein action, Methods of RGS protein inhibition, and G-protein regulators of model organisms. Table of Contents Expression and post-translational modification Assays of GAP activity and allosteric control Electrophysiological methods and RGS-insenstitive Ga subunits Mouse Models of RGS protein action Methods of RGS protein inhibition G-protein regulators of model organisms

Regulators of G-Protein Signaling, Part A.

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (76 download)

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Book Synopsis Regulators of G-Protein Signaling, Part A. by :

Download or read book Regulators of G-Protein Signaling, Part A. written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

G Protein Signaling

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592594301
Total Pages : 246 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis G Protein Signaling by : Alan V. Smrcka

Download or read book G Protein Signaling written by Alan V. Smrcka and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alan V. Smrcka presents a collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry to whole animal studies. Among the readily reproducible techniques presented are those for the purification of G proteins and effectors enzymes, assays of these purified G proteins and effector enzymes, and for the study of G proteins interactions with effectors in intact cells. Additional methods are provided for assaying G protein coupled receptor structure, function, and localization, and for studying the physiological roles for endogenous G proteins.

G Protein-Coupled Receptors in Immune Response and Regulation

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Publisher : Academic Press
ISBN 13 : 0128124040
Total Pages : 398 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis G Protein-Coupled Receptors in Immune Response and Regulation by :

Download or read book G Protein-Coupled Receptors in Immune Response and Regulation written by and published by Academic Press. This book was released on 2017-09-23 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein-Coupled Receptors in Immune Response and Regulation, Volume 136 presents emerging concepts related to the role of GPCRs in immune response and regulation. Users will find updated chapters on a variety of topics, including Beta-adrenergic signaling in the onset and progression of asthma, the Emerging roles of Regulators of G protein signaling (RGS) proteins in the immune system, information on Kinin receptors in immune response and pathogenic infections, and sections on GPCR signaling in C. elegans and its implications in immune response, GPCR Kinases in Inflammatory response and signaling, and GRK2 in Inflammation: Regulation of T cell receptors and IgE signaling. Chapters in this book discuss not only the well-known aspects of GPCR signaling in immunology, but also presents many emerging paradigms that have not yet been reported in classical textbooks. Each chapter presents a forward-looking discussion, providing a glimpse of the tremendous potential associated with the specific receptor systems discussed. Brings together contributions from leading experts in the area of GPCR biology Discusses current paradigms and the future potential of understanding GPCR signaling in immune response and regulation Presents the first of its kind book to focus on specific GPCR systems in various aspects of immunology, all brought together in one volume

RGS Protein Physiology and Pathophysiology

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Publisher : Academic Press
ISBN 13 : 0128029544
Total Pages : 226 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis RGS Protein Physiology and Pathophysiology by :

Download or read book RGS Protein Physiology and Pathophysiology written by and published by Academic Press. This book was released on 2015-06-23 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: RGS Protein Physiology and Pathophysiology describes the current, state-of-the-art research occurring in the laboratories of leaders in the RGS protein field that utilize genetic mouse models to interrogate the function of RGS proteins in vivo. Each chapter describes the elucidated role of a specific RGS protein or family of RGS proteins in normal physiology and/or disease with particular emphasis on how these discoveries inform healthcare and drug discovery. The work is a timely reference as drugs targeting G protein coupled receptors represent 40% of currently marketed therapeutics. Brings together information on the current state of the RGS protein field Contains comprehensive descriptions of the known pathophysiological and physiological functions of RGS proteins, the first such undertaking Gives particular emphasis to the ways these discoveries inform healthcare and drug discovery

Encyclopedia of Signaling Molecules

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Publisher :
ISBN 13 : 9781461464389
Total Pages : pages
Book Rating : 4.4/5 (643 download)

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Book Synopsis Encyclopedia of Signaling Molecules by :

Download or read book Encyclopedia of Signaling Molecules written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

G Protein Pathways, Part A: Receptors

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Publisher : Academic Press
ISBN 13 : 0080884229
Total Pages : 680 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis G Protein Pathways, Part A: Receptors by :

Download or read book G Protein Pathways, Part A: Receptors written by and published by Academic Press. This book was released on 2001-10-09 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences.

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A

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Publisher : Academic Press
ISBN 13 : 0128137738
Total Pages : 182 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A by :

Download or read book G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A written by and published by Academic Press. This book was released on 2018-04-23 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists whose work is drawn from international sources Offers a wide range of perspectives on specific subjects

Molecular Biology of RGS Proteins

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Publisher : Academic Press
ISBN 13 : 9780080911977
Total Pages : 508 pages
Book Rating : 4.9/5 (119 download)

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Book Synopsis Molecular Biology of RGS Proteins by :

Download or read book Molecular Biology of RGS Proteins written by and published by Academic Press. This book was released on 2009-07-21 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of RGS Proteins, a volume of Progress in Molecular Biology and Translational Science, will include historical discussion of RGS proteins, the role of RGS proteins in addiction, depression and Parkinson's disease and the biology and functional regulation of RGS9 isoforms. This publication further discusses RGS proteins in cellular signaling, protein control in lymphocyte function, and alternative splicing of RGS transcripts and nuclear RGS proteins, offering the latest in research of RGS proteins.

Mechanisms and Pathways of Heterotrimeric G Protein Signaling

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Publisher : Academic Press
ISBN 13 : 9780080552699
Total Pages : 290 pages
Book Rating : 4.5/5 (526 download)

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Book Synopsis Mechanisms and Pathways of Heterotrimeric G Protein Signaling by : Stephen Sprang

Download or read book Mechanisms and Pathways of Heterotrimeric G Protein Signaling written by Stephen Sprang and published by Academic Press. This book was released on 2007-10-01 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric Gƒуnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.

Characterization and Cellullar Regulation of the Regulator of G Protein Signaling, RGS14

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Characterization and Cellullar Regulation of the Regulator of G Protein Signaling, RGS14 by : Susanne Hollinger

Download or read book Characterization and Cellullar Regulation of the Regulator of G Protein Signaling, RGS14 written by Susanne Hollinger and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

G Protein-Coupled Receptors - Part A

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Publisher : Elsevier
ISBN 13 : 0323994318
Total Pages : 230 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis G Protein-Coupled Receptors - Part A by :

Download or read book G Protein-Coupled Receptors - Part A written by and published by Elsevier. This book was released on 2022-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes. Covers a broad range of topics related to GPCR activation and signaling Covers several receptor systems with an emphasis on emerging paradigms Covers different processes and model systems with a focus on GPCRs

G Protein-Coupled Receptors - Part B

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Publisher : Elsevier
ISBN 13 : 0323994350
Total Pages : 194 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis G Protein-Coupled Receptors - Part B by :

Download or read book G Protein-Coupled Receptors - Part B written by and published by Elsevier. This book was released on 2023-01-25 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more. Covers a broad range of topics related to GPCR activation and signaling Provides several receptor systems, with an emphasis on emerging paradigms Includes different processes and model systems, with a focus on GPCRs

Handbook of Cell Signaling

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Publisher : Academic Press
ISBN 13 : 0080920918
Total Pages : 3048 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Cell Signaling by : Ralph A. Bradshaw

Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field

Regulation of G Protein-coupled Receptor Function and Expression

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Publisher :
ISBN 13 :
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Regulation of G Protein-coupled Receptor Function and Expression by : Jeffrey L. Benovic

Download or read book Regulation of G Protein-coupled Receptor Function and Expression written by Jeffrey L. Benovic and published by . This book was released on 2000 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text describes many techniques that are used to define the molecular mechanisms involved in receptor regulation. It covers a broad range of important concepts and methodologies in the study of G protein-coupled receptors.

G Protein Signaling

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Publisher :
ISBN 13 : 9783805590532
Total Pages : 0 pages
Book Rating : 4.5/5 (95 download)

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Book Synopsis G Protein Signaling by : Gerd Steding

Download or read book G Protein Signaling written by Gerd Steding and published by . This book was released on 2009-02-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been almost four decades since the discovery of signal transduction by G proteins. Much progress has been made in unraveling their roles in metabolism, cell growth, differentiation and apoptosis. G protein-coupled receptors (GPCRs) now represent a class of important therapeutic targets for drug discovery, and are involved in many different areas including CNS disorders, cardiovascular disease, inflammatory disease, tumor and metabolic disease. This collection of reviews presents the latest findings and perspectives of G protein signaling systems. The focus is placed on the discussion of the regulation and functions of various G protein subunits. New insights into interactions between G proteins and other key players of physiological processes are also put forward to inspire further studies. Researchers in the fields of neuroscience, molecular biology and pharmacology should find this publication useful as it provides an overview of the recent progress in understanding molecular mechanisms of G protein signaling.